[Hub]/) : Traits : Lupus : ← →

chr3:57,622,089-59,105,913

Best TWAS P=1.81e-08 · Best GWAS P=1.28e-07 conditioned to 0.63

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PXK 0.09 0.05 lasso 4 0.04 2.1e-04 -5.1 5.6 2.7e-08 -0.91 0.02 0.98 FALSE
2 GTEx Cells Transformed fibroblasts PXK 0.12 0.13 lasso 9 0.12 2.6e-09 -5.1 -5.1 2.9e-07 1.00 0.02 0.98 FALSE
3 GTEx Spleen PXK 0.33 0.13 lasso 18 0.18 2.2e-05 4.3 5.2 1.7e-07 -0.65 0.04 0.92 FALSE
4 METSIM Adipose PXK 0.04 0.02 lasso 14 0.03 8.9e-05 4.6 5.2 1.6e-07 -0.58 0.12 0.86 FALSE
5 NTR Blood PXK 0.04 0.03 enet 13 0.04 8.5e-13 4.5 5.3 1.0e-07 -0.64 0.31 0.68 FALSE
6 ROSMAP Brain Pre-frontal Cortex PXK 0.24 0.27 enet 38 0.30 1.1e-39 -5.3 5.6 1.8e-08 -0.90 0.02 0.98 TRUE
7 The Cancer Genome Atlas Breast Invasive Carcinoma PDHB 0.04 0.05 enet 7 0.06 8.3e-13 -5.2 -5.2 1.5e-07 0.91 0.01 0.99 FALSE
8 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PDHB 0.05 0.05 lasso 2 0.04 3.7e-03 4.5 -5.3 1.1e-07 0.70 0.02 0.74 FALSE
9 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PDHB 0.06 0.01 blup 40 0.04 1.8e-03 3.9 -5.6 2.4e-08 0.83 0.02 0.83 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma PDHB 0.11 0.15 lasso 7 0.15 1.3e-15 -5.1 -5.4 6.2e-08 0.94 0.01 0.99 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors PDHB 0.25 0.27 lasso 11 0.29 1.1e-10 4.5 -5.2 2.4e-07 0.67 0.08 0.92 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma PDHB 0.07 0.09 lasso 3 0.09 2.7e-09 4.3 -5.1 2.7e-07 0.72 0.09 0.91 FALSE