[Hub]/) : Traits : Lupus : ← →

chr3:57,622,089-59,105,913

Best TWAS P=1.81e-08 · Best GWAS P=1.28e-07 conditioned to 0.63

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	ROSMAP	Brain Pre-frontal Cortex	PXK	0.24	0.27	enet	38	0.30	1.1e-39	-5.3	5.6	1.8e-08	-0.90	0.02	0.98	TRUE
9	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	PDHB	0.06	0.01	blup	40	0.04	1.8e-03	3.9	-5.6	2.4e-08	0.83	0.02	0.83	FALSE
1	GTEx	Adipose Subcutaneous	PXK	0.09	0.05	lasso	4	0.04	2.1e-04	-5.1	5.6	2.7e-08	-0.91	0.02	0.98	FALSE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	PDHB	0.11	0.15	lasso	7	0.15	1.3e-15	-5.1	-5.4	6.2e-08	0.94	0.01	0.99	FALSE
5	NTR	Blood	PXK	0.04	0.03	enet	13	0.04	8.5e-13	4.5	5.3	1.0e-07	-0.64	0.31	0.68	FALSE
8	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PDHB	0.05	0.05	lasso	2	0.04	3.7e-03	4.5	-5.3	1.1e-07	0.70	0.02	0.74	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	PDHB	0.04	0.05	enet	7	0.06	8.3e-13	-5.2	-5.2	1.5e-07	0.91	0.01	0.99	FALSE
4	METSIM	Adipose	PXK	0.04	0.02	lasso	14	0.03	8.9e-05	4.6	5.2	1.6e-07	-0.58	0.12	0.86	FALSE
3	GTEx	Spleen	PXK	0.33	0.13	lasso	18	0.18	2.2e-05	4.3	5.2	1.7e-07	-0.65	0.04	0.92	FALSE
11	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PDHB	0.25	0.27	lasso	11	0.29	1.1e-10	4.5	-5.2	2.4e-07	0.67	0.08	0.92	FALSE
12	The Cancer Genome Atlas	Thyroid Carcinoma	PDHB	0.07	0.09	lasso	3	0.09	2.7e-09	4.3	-5.1	2.7e-07	0.72	0.09	0.91	FALSE
2	GTEx	Cells Transformed fibroblasts	PXK	0.12	0.13	lasso	9	0.12	2.6e-09	-5.1	-5.1	2.9e-07	1.00	0.02	0.98	FALSE