[Hub]/) : Traits : Neuroticism (Nagel 2018) :

chr9:119,768,572-121,177,842

Best TWAS P=2.51e-11 · Best GWAS P=5.2e-13 conditioned to 0.000203

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Whole Blood TLR4 0.13 0.14 lasso 2 0.13 9.8e-12 5.8 -5.8 6.3e-09 -0.61 0.92 0.08 FALSE
2 NTR Blood TLR4 0.07 0.09 lasso 4 0.09 1.1e-26 6.0 -6.7 2.5e-11 -0.67 0.85 0.15 TRUE
3 YFS Blood TLR4 0.55 0.23 bslmm 565 0.39 9.2e-136 6.0 -6.1 1.1e-09 -0.47 0.85 0.15 FALSE