Best TWAS P=2.51e-11 · Best GWAS P=5.2e-13 conditioned to 0.000203
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | TLR4 | 0.13 | 0.14 | lasso | 2 | 0.13 | 9.8e-12 | 5.8 | -5.8 | 6.3e-09 | -0.61 | 0.92 | 0.08 | FALSE |
| 2 | NTR | Blood | TLR4 | 0.07 | 0.09 | lasso | 4 | 0.09 | 1.1e-26 | 6.0 | -6.7 | 2.5e-11 | -0.67 | 0.85 | 0.15 | TRUE |
| 3 | YFS | Blood | TLR4 | 0.55 | 0.23 | bslmm | 565 | 0.39 | 9.2e-136 | 6.0 | -6.1 | 1.1e-09 | -0.47 | 0.85 | 0.15 | FALSE |