Best TWAS P=1.4e-07 · Best GWAS P=2.11e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | GAPVD1 | 0.17 | 0.08 | lasso | 10 | 0.10 | 9.3e-08 | -5.1 | 5.1 | 2.7e-07 | -0.06 | 0.03 | 0.96 | TRUE |
| 2 | GTEx | Pancreas | NEK6 | 0.40 | 0.26 | lasso | 3 | 0.26 | 1.7e-11 | -5.2 | 5.3 | 1.4e-07 | -0.97 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | NEK6 | 0.14 | 0.02 | blup | 87 | 0.05 | 2.8e-03 | -4.5 | 5.2 | 1.8e-07 | -0.60 | 0.01 | 0.69 | FALSE |