[Hub]/) : Traits : Neuroticism (Nagel 2018) :

chr11:133,079,948-134,525,648

Best TWAS P=2.21e-08 · Best GWAS P=4.4e-07 conditioned to 0.0248

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Spleen IGSF9B 0.27 0.01 enet 7 -0.01 5.4e-01 -4.6 -5.2 1.7e-07 0.56 0.01 0.68 FALSE
2 GTEx Testis IGSF9B 0.19 0.09 lasso 7 0.10 3.4e-05 -4.9 -5.2 2.3e-07 0.77 0.01 0.97 FALSE
3 GTEx Thyroid IGSF9B 0.28 0.20 enet 9 0.22 1.2e-16 -4.8 -5.4 8.4e-08 0.73 0.00 0.99 FALSE
4 GTEx Whole Blood IGSF9B 0.11 0.03 enet 22 0.06 7.2e-06 -4.9 -5.6 2.2e-08 0.57 0.00 0.99 TRUE
5 The Cancer Genome Atlas Thyroid Carcinoma IGSF9B 0.08 0.10 lasso 2 0.11 3.8e-11 -4.9 -5.4 5.6e-08 0.70 0.01 0.99 FALSE