Best TWAS P=1.56e-08 · Best GWAS P=3.47e-08 conditioned to 0.329
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DPY19L3 | 0.07 | 0.05 | lasso | 2 | 0.06 | 8.7e-08 | -5.1 | -5.5 | 3.5e-08 | 0.94 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | DPY19L3 | 0.19 | 0.12 | lasso | 6 | 0.10 | 9.4e-08 | -5.1 | -5.6 | 2.6e-08 | 0.95 | 0.02 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | DPY19L3 | 0.04 | 0.04 | lasso | 1 | 0.03 | 7.5e-05 | -5.5 | -5.5 | 4.5e-08 | 1.00 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DPY19L3 | 0.04 | 0.05 | blup | 60 | 0.03 | 6.1e-04 | -5.1 | -5.2 | 2.2e-07 | 0.88 | 0.03 | 0.95 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | ZNF507 | 0.14 | 0.14 | lasso | 5 | 0.18 | 2.4e-17 | -5.4 | -5.7 | 1.6e-08 | 0.90 | 0.00 | 1.00 | TRUE |