Best TWAS P=6.08e-08 · Best GWAS P=1.1e-05 conditioned to 0.248
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FASTKD5 | 0.07 | 0.00 | enet | 18 | 0.03 | 5.4e-05 | 4.3 | 5.2 | 1.9e-07 | -0.64 | 0.02 | 0.77 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | FASTKD5 | 0.06 | 0.01 | bslmm | 401 | 0.03 | 6.0e-05 | -4.3 | 5.4 | 6.1e-08 | -0.65 | 0.01 | 0.88 | TRUE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | FASTKD5 | 0.04 | 0.02 | blup | 50 | 0.03 | 3.3e-04 | -4.3 | 5.2 | 2.5e-07 | -0.82 | 0.00 | 0.52 | FALSE |