[Hub]/) : Traits : Neuroticism (Nagel 2018) : ← →

chr20:32,594,714-34,109,427

Best TWAS P=1.98e-08 · Best GWAS P=7.28e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum NCOA6 0.11 0.10 lasso 10 0.10 4.5e-06 5.2 5.3 8.8e-08 0.92 0.06 0.92 FALSE
2 GTEx Artery Coronary NCOA6 0.20 0.15 enet 27 0.24 1.1e-08 -3.3 5.2 2.5e-07 0.78 0.06 0.93 FALSE
3 GTEx Brain Cortex NCOA6 0.14 0.03 enet 13 0.05 1.6e-02 -3.2 5.2 2.3e-07 0.75 0.06 0.58 FALSE
4 GTEx Colon Sigmoid TP53INP2 0.12 0.09 lasso 3 0.06 2.8e-03 5.0 -5.1 2.8e-07 -0.93 0.04 0.80 FALSE
5 GTEx Colon Transverse NCOA6 0.10 0.06 lasso 8 0.04 4.1e-03 5.4 5.6 2.0e-08 0.96 0.03 0.93 TRUE
6 GTEx Esophagus Gastroesophageal Junction NCOA6 0.24 0.07 lasso 4 0.08 5.9e-04 5.4 5.5 3.0e-08 0.88 0.04 0.90 FALSE
7 GTEx Esophagus Muscularis NCOA6 0.14 0.10 enet 22 0.20 2.6e-12 -3.2 5.1 3.1e-07 0.79 0.05 0.94 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic NCOA6 0.13 0.03 enet 12 0.03 1.5e-02 5.4 5.5 3.2e-08 0.71 0.04 0.88 FALSE
9 GTEx Thyroid TP53INP2 0.09 0.05 lasso 7 0.04 3.7e-04 5.0 -5.4 7.9e-08 -0.96 0.04 0.96 FALSE
10 METSIM Adipose NCOA6 0.05 0.02 bslmm 373 0.02 1.3e-04 4.3 5.1 2.6e-07 0.83 0.06 0.94 FALSE
11 METSIM Adipose TP53INP2 0.05 0.03 lasso 3 0.04 1.3e-06 5.1 -5.2 2.1e-07 -0.91 0.04 0.96 FALSE
12 YFS Blood TP53INP2 0.02 0.02 lasso 15 0.01 1.3e-05 5.0 -5.2 2.0e-07 -0.97 0.04 0.96 FALSE
13 The Cancer Genome Atlas Bladder Urothelial Carcinoma NCOA6 0.05 0.02 blup 66 0.03 1.4e-03 4.7 5.2 1.9e-07 0.91 0.01 0.69 FALSE