[Hub]/) : Traits : Ovarian Cancer : ← →

chr8:81,971,745-83,365,154

Best TWAS P=1.04e-10 · Best GWAS P=1.25e-09 conditioned to 0.331

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland CHMP4C 0.36 0.30 enet 31 0.28 9.0e-11 -6.1 5.3 9.0e-08 -0.87 0 1.00 FALSE
2 GTEx Colon Transverse CHMP4C 0.59 0.34 lasso 8 0.34 6.5e-17 -6.1 5.9 3.5e-09 -0.99 0 1.00 FALSE
3 GTEx Esophagus Mucosa CHMP4C 0.57 0.42 lasso 4 0.43 3.7e-31 -6.1 6.0 2.4e-09 -0.99 0 1.00 FALSE
4 GTEx Lung CHMP4C 0.37 0.21 lasso 6 0.20 2.4e-15 -6.1 6.1 1.1e-09 -0.99 0 1.00 FALSE
5 GTEx Pancreas CHMP4C 0.59 0.42 lasso 6 0.41 1.3e-18 -6.1 6.2 6.6e-10 -1.00 0 1.00 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic CHMP4C 0.47 0.32 lasso 8 0.32 5.8e-18 -6.1 5.9 3.0e-09 -0.98 0 1.00 FALSE
7 GTEx Skin Sun Exposed Lower leg CHMP4C 0.43 0.27 lasso 7 0.27 7.8e-23 -6.1 5.8 6.0e-09 -0.98 0 1.00 FALSE
8 GTEx Thyroid CHMP4C 0.55 0.41 lasso 3 0.42 5.4e-35 -6.1 6.1 1.3e-09 -0.99 0 1.00 FALSE
9 The Cancer Genome Atlas Bladder Urothelial Carcinoma CHMP4C 0.45 0.17 lasso 1 0.15 5.1e-13 -6.1 6.1 1.3e-09 -1.00 0 1.00 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma CHMP4C 0.47 0.24 lasso 4 0.24 2.3e-48 -6.1 6.0 1.9e-09 -0.99 0 1.00 FALSE
11 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CHMP4C 0.24 0.16 lasso 6 0.16 4.0e-08 -6.1 6.0 2.2e-09 -0.99 0 1.00 FALSE
12 The Cancer Genome Atlas Colon Adenocarcinoma CHMP4C 0.75 0.38 lasso 8 0.36 4.7e-22 -6.1 6.1 1.3e-09 -0.99 0 1.00 FALSE
13 The Cancer Genome Atlas Esophageal Carcinoma CHMP4C 0.46 0.03 enet 13 0.16 1.2e-05 -6.1 6.5 1.0e-10 -0.86 0 0.99 TRUE
14 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CHMP4C 0.35 0.21 lasso 3 0.20 1.7e-22 -6.1 6.1 1.3e-09 -1.00 0 1.00 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CHMP4C 0.54 0.23 lasso 1 0.23 5.8e-26 -6.1 6.1 1.3e-09 -1.00 0 1.00 FALSE
16 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CHMP4C 0.61 0.26 lasso 6 0.27 1.5e-15 -6.1 5.9 3.1e-09 -0.99 0 1.00 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma CHMP4C 0.54 0.27 lasso 2 0.27 6.4e-32 -6.1 6.2 7.0e-10 -1.00 0 1.00 FALSE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CHMP4C 0.15 0.08 lasso 2 0.07 2.3e-08 -6.1 6.1 1.3e-09 -1.00 0 1.00 FALSE
19 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CHMP4C 0.45 0.22 enet 8 0.25 9.0e-17 -6.1 6.1 8.7e-10 -0.90 0 1.00 FALSE
20 The Cancer Genome Atlas Pancreatic Adenocarcinoma CHMP4C 0.57 0.30 lasso 2 0.28 4.6e-12 -6.1 6.0 1.5e-09 -0.99 0 1.00 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma CHMP4C 0.64 0.37 enet 9 0.38 1.1e-41 -6.1 6.1 1.1e-09 -0.98 0 1.00 FALSE
22 The Cancer Genome Atlas Rectum Adenocarcinoma CHMP4C 0.84 0.59 lasso 4 0.63 1.5e-18 -6.1 5.8 7.5e-09 -0.97 0 1.00 FALSE
23 The Cancer Genome Atlas Stomach Adenocarcinoma CHMP4C 0.52 0.28 lasso 8 0.29 1.7e-21 -6.1 6.1 1.1e-09 -0.96 0 1.00 FALSE
24 The Cancer Genome Atlas Thyroid Carcinoma CHMP4C 0.73 0.49 lasso 9 0.50 2.6e-55 -6.1 6.0 1.4e-09 -0.99 0 1.00 FALSE
25 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma CHMP4C 0.48 0.24 lasso 2 0.23 3.9e-07 -6.1 5.4 8.0e-08 -0.98 0 1.00 FALSE