[Hub]/) : Traits : Ovarian Cancer :

chr3:155,768,424-157,456,920

Best TWAS P=4.37e-20 · Best GWAS P=1.12e-38 conditioned to 5.66e-16

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts LINC00886 0.11 0.01 lasso 7 0.01 4.1e-02 1.9 7.7 1.2e-14 -0.69 0.08 0.48 TRUE
2 METSIM Adipose LEKR1 0.09 0.09 lasso 3 0.09 1.7e-13 -5.2 5.2 2.5e-07 -0.42 1.00 0.00 FALSE
3 The Cancer Genome Atlas Bladder Urothelial Carcinoma LEKR1 0.10 0.14 lasso 6 0.12 1.8e-10 -5.2 5.3 1.4e-07 -0.42 1.00 0.00 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma LEKR1 0.13 0.16 lasso 5 0.15 3.6e-30 -5.3 5.4 6.8e-08 -0.42 1.00 0.00 FALSE
5 The Cancer Genome Atlas Colon Adenocarcinoma LEKR1 0.16 0.12 lasso 2 0.09 5.2e-06 -5.3 5.3 1.1e-07 -0.41 0.85 0.09 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC100287227 0.09 0.02 enet 8 0.02 1.3e-03 1.9 8.2 2.7e-16 -0.57 0.01 0.54 TRUE
7 The Cancer Genome Atlas Lung Adenocarcinoma LEKR1 0.09 0.12 lasso 1 0.11 1.2e-12 -5.3 5.3 1.0e-07 -0.42 1.00 0.00 FALSE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LEKR1 0.23 0.27 lasso 2 0.26 1.7e-17 -5.2 5.2 1.7e-07 -0.43 1.00 0.00 FALSE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma LEKR1 0.14 0.15 lasso 1 0.15 9.8e-07 -5.3 5.3 1.0e-07 -0.42 0.40 0.40 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma LEKR1 0.20 0.19 lasso 5 0.19 2.6e-19 -5.3 5.1 3.0e-07 -0.41 1.00 0.00 FALSE
11 The Cancer Genome Atlas Stomach Adenocarcinoma LOC100287227 0.07 0.01 blup 47 0.02 9.8e-03 -9.5 9.2 4.4e-20 -0.71 0.02 0.25 TRUE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors LEKR1 0.12 0.03 blup 114 0.03 2.5e-02 -3.5 5.7 1.1e-08 -0.44 0.02 0.54 FALSE
13 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma LEKR1 0.21 0.14 lasso 4 0.10 8.6e-04 -5.3 5.3 1.0e-07 -0.42 0.08 0.20 FALSE