Best TWAS P=1.23e-07 · Best GWAS P=2.7e-07 conditioned to 0.0698
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | IDUA | 0.09 | 0.09 | lasso | 4 | 0.07 | 1.5e-06 | 5.1 | 5.3 | 1.4e-07 | 1.00 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | DGKQ | 0.32 | 0.23 | enet | 18 | 0.26 | 2.3e-21 | 5.3 | 5.3 | 1.3e-07 | 0.93 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Coronary | SLC26A1 | 0.39 | 0.20 | enet | 13 | 0.23 | 2.4e-08 | -4.2 | -5.2 | 1.8e-07 | -0.83 | 0.02 | 0.97 | FALSE |
| 4 | GTEx | Breast Mammary Tissue (Female) | SLC26A1 | 0.30 | 0.22 | lasso | 6 | 0.22 | 2.9e-07 | -4.3 | -5.3 | 1.5e-07 | -0.56 | 0.15 | 0.61 | FALSE |
| 5 | GTEx | Lung | DGKQ | 0.36 | 0.29 | lasso | 5 | 0.32 | 5.6e-25 | 5.3 | 5.2 | 2.6e-07 | 0.96 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Pancreas | SLC26A1 | 0.38 | 0.26 | lasso | 9 | 0.28 | 3.0e-12 | -4.3 | -5.2 | 2.0e-07 | -0.73 | 0.08 | 0.91 | FALSE |
| 7 | GTEx | Stomach | SLC26A1 | 0.26 | 0.17 | enet | 14 | 0.16 | 4.0e-08 | -4.3 | -5.3 | 1.2e-07 | -0.74 | 0.03 | 0.96 | TRUE |
| 8 | GTEx | Whole Blood | DGKQ | 0.37 | 0.27 | enet | 18 | 0.29 | 5.4e-27 | 5.1 | 5.2 | 1.7e-07 | 0.97 | 0.00 | 1.00 | FALSE |
| 9 | GTEx | Whole Blood | SLC26A1 | 0.07 | 0.05 | enet | 13 | 0.07 | 3.0e-07 | 5.1 | -5.2 | 1.8e-07 | -0.91 | 0.00 | 1.00 | FALSE |