Best TWAS P=1.09e-09 · Best GWAS P=1.83e-09 conditioned to 0.0808
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PDLIM5 | 0.18 | 0.14 | lasso | 6 | 0.19 | 1.6e-14 | 4.8 | 6.1 | 1.1e-09 | -0.82 | 0.04 | 0.96 | TRUE |
| 2 | GTEx | Nerve Tibial | PDLIM5 | 0.09 | 0.07 | lasso | 2 | 0.03 | 2.3e-03 | -5.9 | 6.1 | 1.4e-09 | -0.96 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | PDLIM5 | 0.10 | 0.07 | lasso | 5 | 0.07 | 2.1e-06 | 4.8 | 5.2 | 1.6e-07 | -0.74 | 0.17 | 0.83 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | PDLIM5 | 0.06 | 0.05 | blup | 121 | 0.04 | 5.4e-04 | 4.5 | 5.1 | 3.1e-07 | -0.63 | 0.47 | 0.49 | FALSE |