Best TWAS P=6.4e-11 · Best GWAS P=4.82e-28 conditioned to 7.11e-17
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | NKX3-1 | 0.30 | 0.33 | enet | 37 | 0.36 | 6.3e-123 | 4.1 | 6.5 | 6.4e-11 | -0.01 | 1.00 | 0.00 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NKX3-1 | 0.03 | 0.00 | lasso | 3 | 0.02 | 2.0e-04 | -3.1 | 5.4 | 6.0e-08 | 0.61 | 0.03 | 0.57 | TRUE |