[Hub]/) : Traits : Prostate Cancer : ← →

chr10:50,336,129-52,456,629

Best TWAS P=7.17e-68 · Best GWAS P=6.13e-59 conditioned to 0.00303

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue AGAP7 0.50 0.21 enet 27 0.35 5.5e-19 0.49 -5.3 9.4e-08 -0.20 1.00 0.00 FALSE
2 GTEx Breast Mammary Tissue (Female) RP11-592B15.4 0.14 0.06 enet 7 0.09 1.3e-03 -2.50 -7.4 1.8e-13 -0.46 0.03 0.45 FALSE
3 GTEx Breast Mammary Tissue (Female) PARG 0.10 -0.01 enet 21 -0.01 9.5e-01 0.14 5.7 1.1e-08 0.42 0.02 0.13 FALSE
4 GTEx Colon Sigmoid AGAP7 0.36 0.20 enet 13 0.26 6.6e-10 -3.47 -7.0 1.8e-12 -0.24 0.88 0.08 FALSE
5 GTEx Esophagus Muscularis AGAP7 0.26 0.14 enet 21 0.18 3.8e-11 0.49 -5.8 6.7e-09 -0.23 0.98 0.01 FALSE
6 GTEx Liver AGAP7 0.37 0.01 enet 22 0.10 1.1e-03 -3.47 -5.9 3.0e-09 -0.26 0.02 0.06 FALSE
7 GTEx Prostate NCOA4 0.20 0.18 lasso 2 0.16 6.4e-05 17.20 17.4 7.2e-68 0.92 0.00 0.97 TRUE
8 GTEx Whole Blood AGAP7 0.13 0.08 lasso 3 0.10 6.2e-10 14.43 -12.3 1.5e-34 -0.79 0.88 0.09 FALSE
9 NTR Blood NCOA4 0.02 0.01 enet 6 0.01 2.6e-04 14.66 -15.1 3.3e-51 -0.87 0.02 0.97 FALSE
10 YFS Blood AGAP6 0.13 0.10 enet 24 0.10 8.0e-32 14.43 -13.0 9.7e-39 -0.90 0.89 0.11 TRUE
11 YFS Blood AGAP8 0.36 0.32 bslmm 200 0.34 1.1e-116 14.43 -12.9 2.5e-38 -0.87 1.00 0.00 FALSE
12 YFS Blood NCOA4 0.15 0.15 lasso 5 0.18 9.5e-56 14.43 -13.2 1.4e-39 -0.90 1.00 0.00 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma NCOA4 0.05 0.01 enet 2 0.02 1.1e-03 7.10 9.5 2.2e-21 0.36 0.00 0.51 FALSE