[Hub]/) : Traits : Prostate Cancer : ← →

chr10:50,336,129-52,456,629

Best TWAS P=7.17e-68 · Best GWAS P=6.13e-59 conditioned to 0.00303

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Prostate	NCOA4	0.20	0.18	lasso	2	0.16	6.4e-05	17.20	17.4	7.2e-68	0.92	0.00	0.97	TRUE
10	YFS	Blood	AGAP6	0.13	0.10	enet	24	0.10	8.0e-32	14.43	-13.0	9.7e-39	-0.90	0.89	0.11	TRUE
9	NTR	Blood	NCOA4	0.02	0.01	enet	6	0.01	2.6e-04	14.66	-15.1	3.3e-51	-0.87	0.02	0.97	FALSE
12	YFS	Blood	NCOA4	0.15	0.15	lasso	5	0.18	9.5e-56	14.43	-13.2	1.4e-39	-0.90	1.00	0.00	FALSE
11	YFS	Blood	AGAP8	0.36	0.32	bslmm	200	0.34	1.1e-116	14.43	-12.9	2.5e-38	-0.87	1.00	0.00	FALSE
8	GTEx	Whole Blood	AGAP7	0.13	0.08	lasso	3	0.10	6.2e-10	14.43	-12.3	1.5e-34	-0.79	0.88	0.09	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	NCOA4	0.05	0.01	enet	2	0.02	1.1e-03	7.10	9.5	2.2e-21	0.36	0.00	0.51	FALSE
2	GTEx	Breast Mammary Tissue (Female)	RP11-592B15.4	0.14	0.06	enet	7	0.09	1.3e-03	-2.50	-7.4	1.8e-13	-0.46	0.03	0.45	FALSE
4	GTEx	Colon Sigmoid	AGAP7	0.36	0.20	enet	13	0.26	6.6e-10	-3.47	-7.0	1.8e-12	-0.24	0.88	0.08	FALSE
6	GTEx	Liver	AGAP7	0.37	0.01	enet	22	0.10	1.1e-03	-3.47	-5.9	3.0e-09	-0.26	0.02	0.06	FALSE
5	GTEx	Esophagus Muscularis	AGAP7	0.26	0.14	enet	21	0.18	3.8e-11	0.49	-5.8	6.7e-09	-0.23	0.98	0.01	FALSE
3	GTEx	Breast Mammary Tissue (Female)	PARG	0.10	-0.01	enet	21	-0.01	9.5e-01	0.14	5.7	1.1e-08	0.42	0.02	0.13	FALSE
1	GTEx	Breast Mammary Tissue	AGAP7	0.50	0.21	enet	27	0.35	5.5e-19	0.49	-5.3	9.4e-08	-0.20	1.00	0.00	FALSE