[Hub]/) : Traits : Prostate Cancer : ← →

chr17:3,587-1,381,005

Best TWAS P=3.24e-13 · Best GWAS P=3.15e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	GEMIN4	0.05	0.06	lasso	4	0.05	3.6e-06	7.0	-7.3	3.2e-13	-0.99	0.00	1.00	TRUE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	VPS53	0.03	0.04	lasso	1	0.03	1.1e-04	7.0	-7.0	3.2e-12	-1.00	0.00	0.99	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	VPS53	0.13	0.15	lasso	4	0.15	7.2e-16	6.9	-6.9	5.2e-12	-0.99	0.00	1.00	FALSE
4	GTEx	Colon Transverse	FAM57A	0.31	0.27	lasso	3	0.27	2.3e-13	6.9	-6.7	1.9e-11	-0.97	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	FAM57A	0.17	0.16	enet	8	0.20	8.6e-21	7.0	-6.7	2.7e-11	-0.94	0.00	1.00	FALSE
5	GTEx	Colon Transverse	GEMIN4	0.12	0.06	enet	7	0.02	2.3e-02	5.1	-6.1	8.7e-10	-0.92	0.01	0.96	FALSE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	VPS53	0.09	0.06	blup	110	0.04	1.5e-05	5.1	-5.9	3.9e-09	-0.82	0.02	0.98	FALSE
12	The Cancer Genome Atlas	Lung Adenocarcinoma	VPS53	0.10	0.03	blup	113	0.06	1.9e-07	7.0	-5.9	4.3e-09	-0.71	0.00	1.00	FALSE
3	GTEx	Breast Mammary Tissue (Male)	RP11-1260E13.4	0.22	0.08	lasso	3	0.05	2.6e-02	4.6	5.8	5.1e-09	0.90	0.02	0.48	FALSE
6	GTEx	Pancreas	FAM57A	0.12	0.04	lasso	4	0.05	3.5e-03	4.3	-5.7	9.2e-09	-0.88	0.01	0.94	FALSE
7	GTEx	Testis	RNMTL1	0.39	0.31	enet	24	0.34	1.5e-15	6.0	-5.7	1.6e-08	-0.54	0.34	0.66	FALSE
1	CommonMind	Brain Pre-frontal Cortex	VPS53	0.09	0.05	enet	10	0.08	5.9e-10	5.5	-5.4	7.7e-08	-0.81	0.01	0.99	FALSE
9	The Cancer Genome Atlas	Glioblastoma Multiforme	FAM57A	0.23	0.11	blup	50	0.09	1.3e-03	2.9	5.3	1.0e-07	0.45	0.03	0.26	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	RNMTL1	0.09	0.02	enet	18	0.04	9.3e-05	6.0	5.3	1.2e-07	0.46	0.00	0.99	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	VPS53	0.29	0.17	lasso	6	0.28	9.0e-37	1.6	-5.2	1.7e-07	-0.66	0.08	0.92	FALSE
2	GTEx	Brain Cortex	VPS53	0.31	0.16	enet	22	0.07	6.3e-03	5.9	-5.2	2.0e-07	-0.81	0.01	0.98	FALSE