Best TWAS P=2.24e-44 · Best GWAS P=1.66e-73 conditioned to 1.69e-30
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C17orf78 | 0.13 | 0.01 | blup | 383 | 0.02 | 0.00118 | 1.3 | 5.8 | 6.4e-09 | -0.26 | 0.74 | 0.05 | TRUE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | HNF1B | 0.08 | 0.00 | blup | 79 | 0.03 | 0.00269 | -7.5 | 10.7 | 1.6e-26 | -0.17 | 0.02 | 0.06 | TRUE |
| 3 | The Cancer Genome Atlas | Esophageal Carcinoma | HNF1B | 0.45 | 0.00 | enet | 27 | 0.12 | 0.00013 | -1.9 | -5.2 | 2.5e-07 | 0.29 | 0.01 | 0.14 | TRUE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | HNF1B | 0.13 | 0.01 | blup | 79 | 0.04 | 0.00875 | -3.8 | -7.2 | 5.4e-13 | 0.31 | 0.01 | 0.04 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | HNF1B | 0.05 | 0.03 | blup | 79 | 0.01 | 0.03990 | -2.7 | 14.0 | 2.2e-44 | -0.45 | 0.02 | 0.22 | TRUE |