Best TWAS P=2.04e-12 · Best GWAS P=6.29e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 8 | GTEx | Skin Sun Exposed Lower leg | AC011526.1 | 0.12 | 0.11 | lasso | 4 | 0.10 | 7.2e-09 | -6.9 | 7.0 | 2.0e-12 | -1.00 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Adipose Subcutaneous | AC011526.1 | 0.33 | 0.21 | lasso | 5 | 0.19 | 3.8e-15 | -6.9 | 6.9 | 4.1e-12 | -0.99 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Breast Mammary Tissue | AC011526.1 | 0.17 | 0.17 | lasso | 1 | 0.15 | 2.5e-08 | -6.9 | 6.9 | 6.3e-12 | -1.00 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Breast Mammary Tissue (Female) | AC011526.1 | 0.20 | 0.07 | lasso | 2 | 0.04 | 2.2e-02 | -6.9 | 6.8 | 9.6e-12 | -1.00 | 0.01 | 0.90 | FALSE |
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100505495 | 0.30 | 0.32 | bslmm | 369 | 0.33 | 1.1e-40 | -6.9 | 6.7 | 2.5e-11 | -0.99 | 0.00 | 1.00 | FALSE |
| 7 | GTEx | Nerve Tibial | AC011526.1 | 0.18 | 0.12 | lasso | 3 | 0.12 | 5.6e-09 | -6.9 | 6.6 | 3.4e-11 | -0.95 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Breast Mammary Tissue (Male) | AC011526.1 | 0.07 | 0.05 | lasso | 2 | -0.01 | 4.4e-01 | -6.9 | 6.6 | 4.8e-11 | -0.98 | 0.01 | 0.63 | FALSE |
| 6 | GTEx | Cells Transformed fibroblasts | AC006129.4 | 0.29 | 0.26 | lasso | 6 | 0.25 | 1.6e-18 | -5.2 | -6.2 | 5.8e-10 | 0.70 | 0.59 | 0.41 | FALSE |