[Hub]/) : Traits : Prostate Cancer : ← →

chr1:153,220,716-155,699,118

Best TWAS P=3.37e-09 · Best GWAS P=3.76e-08 conditioned to 0.0373

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere DCST2 0.45 0.10 lasso 6 0.16 6.6e-05 4.3 -5.5 3.4e-08 0.11 0.02 0.84 TRUE
2 GTEx Colon Transverse RP11-422P24.10 0.09 0.12 lasso 8 0.08 1.1e-04 5.3 -5.3 1.2e-07 -0.94 0.04 0.96 FALSE
3 GTEx Heart Left Ventricle CRTC2 0.09 0.00 enet 11 0.00 4.0e-01 4.6 -5.3 1.1e-07 -0.54 0.06 0.58 FALSE
4 GTEx Muscle Skeletal CREB3L4 0.03 0.05 lasso 3 0.04 1.4e-04 5.5 5.5 4.0e-08 0.99 0.03 0.96 FALSE
5 GTEx Muscle Skeletal RP11-422P24.10 0.03 0.02 enet 7 0.01 1.4e-02 5.4 -5.2 1.9e-07 -0.91 0.04 0.93 FALSE
6 NTR Blood SLC39A1 0.02 0.02 lasso 3 0.02 5.8e-06 5.4 5.4 5.9e-08 0.94 0.04 0.96 FALSE
7 NTR Blood TPM3 0.01 0.00 blup 331 0.00 2.6e-02 -2.1 5.5 3.9e-08 0.59 0.08 0.23 FALSE
8 YFS Blood CRTC2 0.01 0.00 blup 301 0.00 7.6e-02 5.4 -5.9 3.4e-09 -0.86 0.04 0.91 TRUE
9 The Cancer Genome Atlas Breast Invasive Carcinoma NUP210L 0.02 0.02 blup 72 0.02 5.2e-05 5.4 5.3 1.4e-07 0.95 0.02 0.98 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma TPM3 0.01 0.01 lasso 3 0.01 9.2e-03 5.4 5.7 1.2e-08 0.90 0.00 0.84 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma SLC39A1 0.02 0.02 blup 35 0.01 3.0e-02 5.3 5.2 1.9e-07 0.94 0.02 0.67 FALSE
12 The Cancer Genome Atlas Skin Cutaneous Melanoma DENND4B 0.10 0.09 enet 2 0.04 2.8e-02 5.4 5.4 8.2e-08 0.94 0.01 0.65 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma NUP210L 0.06 0.04 blup 71 0.05 1.5e-05 5.3 5.2 1.7e-07 0.92 0.03 0.96 FALSE