[Hub]/) : Traits : Prostate Cancer : ←

chr22:42,835,727-44,282,307

Best TWAS P=4.97e-34 · Best GWAS P=3.18e-43 conditioned to 8.42e-30

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
16	The Cancer Genome Atlas	Thyroid Carcinoma	BIK	0.11	0.07	lasso	5	0.08	2.8e-08	-12.0	12.2	5.0e-34	-0.22	0.99	0.00	TRUE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	MCAT	0.15	0.09	lasso	2	0.11	6.6e-07	-11.9	11.4	5.3e-30	-0.16	0.92	0.00	FALSE
4	GTEx	Brain Nucleus accumbens basal ganglia	TTLL12	0.29	-0.01	lasso	7	0.02	8.3e-02	-10.8	9.1	6.6e-20	-0.41	0.08	0.07	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TTLL1	0.05	0.00	blup	75	0.01	1.7e-02	-2.1	-8.2	2.9e-16	0.44	0.01	0.07	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	MCAT	0.12	0.09	blup	65	0.09	1.8e-10	-7.6	8.2	3.8e-16	-0.21	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MCAT	0.16	0.09	bslmm	552	0.09	3.9e-11	-7.8	7.9	2.9e-15	-0.21	1.00	0.00	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	MCAT	0.02	0.02	lasso	2	0.02	7.6e-05	-7.8	7.8	5.0e-15	-0.11	0.35	0.02	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	BIK	0.05	0.01	lasso	2	0.01	4.9e-02	-7.8	-7.7	1.3e-14	0.10	0.03	0.09	FALSE
7	YFS	Blood	TSPO	0.22	0.08	bslmm	550	0.11	2.5e-34	6.3	6.5	8.8e-11	-0.30	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	TTLL12	0.07	0.02	blup	83	0.05	9.9e-06	-4.3	6.4	1.9e-10	-0.06	0.15	0.43	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	BIK	0.05	0.02	blup	72	0.05	4.2e-06	-7.6	-6.3	2.7e-10	0.20	0.33	0.02	FALSE
2	GTEx	Adrenal Gland	TSPO	0.38	0.11	lasso	7	0.17	1.3e-06	6.0	-6.1	1.2e-09	0.18	0.88	0.01	FALSE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	MCAT	0.06	0.05	lasso	2	0.05	2.3e-05	-7.6	5.6	1.9e-08	-0.09	0.59	0.03	FALSE
6	GTEx	Testis	TTLL12	0.38	0.20	enet	31	0.28	6.3e-13	-4.3	5.4	8.5e-08	-0.10	1.00	0.00	FALSE
3	GTEx	Brain Frontal Cortex BA9	TTLL12	0.34	0.06	enet	21	0.10	1.6e-03	5.9	5.3	1.4e-07	-0.41	0.07	0.25	FALSE
5	GTEx	Nerve Tibial	TSPO	0.33	0.26	lasso	6	0.28	8.4e-20	-4.9	-5.2	2.4e-07	0.05	1.00	0.00	FALSE