TWAS hub - F2RL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2640	0.0380	0.0e+00	0.273	0.241	0.282	0.284	0.288	3.3e-33	5.1e-29	1.9e-34	1.0e-34	2.7e-35
2	METSIM	Adipose	0.0935	0.0258	4.5e-06	0.039	0.053	0.073	0.059	0.065	1.4e-06	1.8e-08	3.9e-11	2.9e-09	5.6e-10
3	NTR	Blood	0.1045	0.0173	0.0e+00	0.128	0.098	0.130	0.126	0.133	5.3e-39	8.4e-30	1.1e-39	2.5e-38	8.9e-41
4	ROSMAP	Brain Pre-frontal Cortex	0.1562	0.0294	2.4e-13	0.164	0.115	0.154	0.155	0.168	1.6e-20	1.4e-14	2.3e-19	2.1e-19	4.1e-21
5	TCGA	Breast Invasive Carcinoma	0.0245	0.0124	2.7e-03	0.003	0.007	0.009	NA	0.009	8.2e-02	1.2e-02	5.5e-03	NA	4.7e-03
6	TCGA	Brain Lower Grade Glioma	0.0522	0.0230	6.1e-06	0.051	0.048	0.045	NA	0.050	1.8e-06	3.7e-06	7.6e-06	NA	2.4e-06
7	TCGA	Prostate Adenocarcinoma	0.0227	0.0137	7.7e-03	0.009	0.022	0.013	NA	0.016	3.4e-02	2.2e-03	1.5e-02	NA	7.7e-03
8	TCGA	Soft Tissue Sarcoma	0.0820	0.0470	6.5e-03	0.049	0.009	0.007	NA	0.061	7.1e-04	9.0e-02	1.2e-01	NA	1.6e-04
9	TCGA	Thyroid Carcinoma	0.0540	0.0290	5.2e-03	0.035	0.030	0.034	NA	0.033	2.4e-04	6.3e-04	2.7e-04	NA	3.4e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Depression (Nagel 2018)	5.5	8.2	12.8	2.9	2.8	3.2	2.6	2.0	3.2	3.6	1.8	3.4
Birth weight of first child	4.8	8.7	13.2	3.5	2.8	3.3	3.6	2.5	3.3	1.6	2.6	2.6
Ever had stillbirth, spontaneous miscarriage or termination	4.7	5.0	9.1	-2.2	-1.7	-2.3	-2.0	-1.4	-2.3	-2.9	-1.7	-3.0
Blood Platelet Count	4.5	52.8	116.6	7.4	2.5	6.1	7.3	-4.6	7.9	10.8	3.4	10.6
Illnesses of siblings: Diabetes	4.3	5.2	8.5	-2.7	-2.4	-2.5	-2.5	-1.7	-2.7	-2.9	-1.3	-1.0
Medication: Seretide 50 evohaler	3.8	4.3	6.5	-2.3	-1.9	-2.3	-2.3	-1.7	-2.2	-2.5	-2.0	-1.0
Age started oral contraceptive pill	3.8	4.8	7.1	2.5	2.6	2.4	2.6	2.7	2.6	1.6	0.5	0.8
Had other major operations	3.5	4.2	10.5	2.1	2.2	2.0	2.3	1.5	1.6	1.9	3.2	-0.5
Relative age voice broke	3.4	5.2	8.3	2.7	1.7	2.6	2.9	1.8	2.8	2.5	1.3	1.6
Birth weight	3.4	7.4	16.6	3.0	2.3	2.6	3.0	1.7	3.2	2.5	0.7	4.1
Frequency of depressed mood in last 2 weeks	3.2	4.5	8.6	2.1	2.3	2.3	1.8	1.5	2.4	2.3	0.9	2.9
Alcohol usually taken with meals	3.0	4.9	6.6	-2.6	-1.7	-2.3	-2.6	-0.5	-2.3	-2.2	-2.6	-2.6
Average weekly champagne plus white wine intake	2.9	4.0	6.4	-2.3	-1.2	-2.1	-2.5	-0.7	-2.1	-2.4	-2.5	-1.5
Prostate Cancer	2.6	3.6	6.2	-1.9	-2.5	-2.1	-1.8	-1.3	-2.0	-2.3	-1.2	-1.6
Handedness (chirality/laterality): Left-handed	2.5	3.1	4.7	-2.0	-2.1	-1.9	-1.8	-1.4	-1.8	-2.2	-1.5	0.6
Peak expiratory flow (PEF)	2.4	5.6	9.5	-2.5	-2.7	-2.6	-2.4	-3.1	-2.3	-2.4	-1.9	-1.0
Mouth/teeth dental problems: Bleeding gums	2.4	3.1	5.6	-1.8	-1.5	-1.9	-2.0	-1.0	-1.6	-2.4	-2.3	0.5
Medication: Amlodipine	2.3	3.2	7.1	-2.1	-1.6	-2.2	-2.0	-2.7	-2.2	-0.2	-1.0	-0.4
Average weekly beer plus cider intake	2.3	3.4	11.1	2.0	1.1	1.6	2.0	0.5	1.8	1.3	1.6	3.3
Coronary Artery Disease (CAD)	2.2	2.6	6.2	-1.6	-2.0	-1.6	-1.5	0.1	-1.7	0.1	-1.7	-2.5
Headache pain in last month	2.0	3.5	5.5	2.2	1.9	2.1	2.4	2.1	2.2	1.5	1.2	0.5
Other serious medical condition/disability diagnosed by doctor	1.9	2.5	3.9	1.7	1.8	1.7	1.6	2.0	1.7	1.6	0.7	0.7
Number of full brothers	1.9	2.3	6.4	1.8	1.0	1.8	1.4	0.8	2.0	0.7	0.7	2.5
Number of full sisters	1.9	2.3	3.0	1.5	1.3	1.7	1.4	1.5	1.5	1.4	1.6	1.4
Fasting Glucose	1.8	2.1	7.1	0.6	0.9	2.7	1.5	0.7	1.7	1.3	1.9	-0.1
Fed-up feelings	1.8	3.3	6.5	-1.9	-1.4	-2.0	-2.0	-1.5	-1.6	-1.9	-2.5	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.7	11.0	-2.3	-2.8	-2.4	-2.2	-3.3	-2.2	-3.0	-1.0	-1.4
Glaucoma (self-reported)	1.8	2.1	3.3	1.7	1.5	1.7	1.8	1.8	1.8	0.9	0.8	0.5
Forced vital capacity (FVC), Best measure	1.8	6.5	10.8	-2.6	-3.2	-2.7	-2.6	-3.3	-2.6	-2.6	-1.3	-1.4
Blood Red Count	1.7	16.0	38.9	-3.9	-2.5	-3.9	-3.9	-1.3	-4.3	-6.2	-2.0	-5.5
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.7	4.9	1.6	2.2	1.7	1.6	1.7	1.8	1.2	0.5	1.9
Depression (self-reported)	1.7	2.0	3.2	1.5	1.3	1.5	1.3	1.2	1.6	1.5	0.7	1.8
Lung cancer (father)	1.7	2.0	3.9	-1.5	-1.9	-1.5	-1.2	-1.5	-1.6	-2.0	-0.3	-0.5
Exposure to tobacco smoke outside home	1.7	2.2	3.5	1.7	0.9	1.9	1.5	1.2	1.9	1.5	1.4	1.2
Comparative height size at age 10	1.7	9.4	15.7	-3.1	-3.3	-3.3	-2.9	-2.4	-3.3	-3.0	-1.9	-4.0
Commuting to job workplace: Car/motor vehicle	1.7	1.9	4.0	1.0	2.0	1.3	0.8	1.6	0.9	1.7	1.9	0.5
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.6	9.4	-1.6	-2.9	-2.0	-1.3	-3.1	-1.8	-1.2	-0.7	-1.0
Relative age of first facial hair	1.6	3.3	5.7	2.4	1.3	2.2	2.4	1.6	2.3	1.3	1.1	1.0
Medication: Ventolin 100micrograms inhaler	1.6	2.0	5.0	-1.4	-1.2	-1.6	-1.8	-0.8	-1.3	-1.1	-2.2	-0.9
Long-standing illness, disability or infirmity	1.6	2.5	4.8	1.2	2.1	1.5	1.0	1.8	1.0	2.1	2.2	0.1
Smoking Status	1.5	3.6	9.0	-2.0	-2.4	-2.1	-2.0	-1.4	-1.7	-0.6	-3.0	0.2
Number of treatments/medications taken	1.5	2.7	3.7	1.7	1.4	1.6	1.9	1.9	1.4	1.7	1.9	0.4
Pain all over the body in last month	1.5	1.6	2.4	1.4	1.3	1.4	1.3	1.0	1.5	1.5	0.5	1.3
Mean time to correctly identify matches	1.5	2.9	8.3	1.6	2.1	1.8	1.4	2.9	1.7	1.4	0.5	1.0
Triglycerides	1.4	2.4	4.7	1.5	1.8	1.5	1.5	2.2	1.5	1.6	0.6	1.3
Eye problems/disorders: Cataract	1.4	1.7	2.5	1.5	0.9	1.5	1.3	0.5	1.6	1.4	1.2	1.2
Age at First Birth	1.3	2.0	4.1	-1.5	-0.9	-1.4	-1.7	-2.0	-1.8	-1.0	0.2	-1.1
HbA1C	1.3	1.5	2.8	-1.6	-0.8	-1.5	-1.6	-1.5	-1.7	-0.0	-0.4	-0.4
Diabetes (father)	1.3	1.6	5.1	-1.2	-0.3	-1.1	-1.1	0.6	-1.2	-2.3	-1.0	-1.6
Hand grip strength (right)	1.3	3.7	6.8	-2.0	-1.9	-2.3	-1.9	-2.6	-2.0	-1.4	-1.4	-1.3
Noisy workplace	1.3	1.6	2.9	-1.5	-1.0	-1.5	-1.5	0.1	-1.5	-1.7	-1.2	-0.4
Eye problems/disorders: Glaucoma	1.3	1.5	2.4	1.4	1.0	1.3	1.6	1.1	1.2	1.3	1.4	-0.1
Alcohol drinker status: Never	1.3	1.6	2.1	-1.4	-0.9	-1.4	-1.4	-0.7	-1.4	-1.4	-1.3	-1.2
HDL Cholesterol	1.2	2.0	3.8	-1.4	-0.8	-1.5	-1.6	-1.2	-1.1	-1.9	-1.8	-0.8
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	3.0	1.2	1.7	1.3	1.1	1.4	1.3	1.2	0.2	-0.2
Forced expiratory volume in 1-second (FEV1)	1.2	4.1	12.1	-1.9	-2.6	-2.2	-1.7	-3.5	-1.9	-1.7	-0.9	-0.4
High blood pressure (siblings)	1.2	1.7	2.9	-1.7	-0.8	-1.7	-1.4	-1.5	-1.7	-0.7	-0.9	1.0
Had major operations	1.2	1.4	2.0	-1.4	-1.0	-1.4	-1.3	-0.1	-1.4	-1.0	-1.1	-1.3
Bipolar Disorder (2011)	1.1	1.1	3.7	-1.6	-1.2	-1.3	-1.9	0.0	0.0	0.0	0.0	0.0
Supplements: Zinc	1.1	1.2	3.3	-0.9	-0.8	-1.0	-0.9	-1.4	-1.0	-1.8	-0.4	-0.9
Taking other prescription medications	1.1	1.7	4.7	1.2	1.4	1.0	1.2	1.6	1.0	2.2	0.4	0.5
Age when periods started (menarche)	1.1	2.7	4.5	2.0	1.5	1.9	1.9	0.8	2.1	1.7	0.8	1.5
Father’s age at death	1.1	1.4	2.7	1.6	0.7	1.5	1.5	0.6	1.7	1.0	0.8	0.7
Blood clot in the leg (DVT)	1.1	1.5	5.0	-1.0	0.4	-0.9	-0.9	0.4	-0.8	-1.6	-1.4	-2.2
Knee pain experienced in last month	1.1	1.7	4.5	-1.5	-0.3	-1.3	-1.5	-0.6	-1.7	-1.0	0.2	-2.1
Supplements: Calcium	1.1	1.2	2.4	-0.9	-0.9	-1.1	-0.9	-0.9	-0.8	-1.5	-1.6	-0.9
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	4.1	-0.9	0.6	-0.8	-0.9	0.5	-0.7	-1.6	-1.4	-2.0
Body Mass Index (BMI) (2010)	1.0	1.4	3.0	-1.1	-1.7	-1.2	-1.1	-1.2	-1.0	-0.8	-1.5	-0.8
Type 2 Diabetes (T2D) (2012)	1.0	1.1	5.7	-0.6	-0.9	-0.7	0.0	-1.2	-0.8	-0.8	0.2	-2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	3.8	0.9	1.5	1.1	0.6	0.2	1.2	1.5	0.1	1.9
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	2.8	-1.1	-1.4	-1.2	-1.1	-1.5	-0.9	-1.5	-1.7	-0.6
Medication: Paracetamol	1.0	1.6	2.7	1.4	1.6	1.3	1.6	1.1	1.3	1.1	1.2	0.5
Qualifications: nursing, teaching	1.0	1.5	3.6	-1.1	-0.6	-1.3	-0.9	-1.5	-1.4	-1.3	-0.2	-1.9
Number of self-reported non-cancer illnesses	1.0	1.8	4.5	1.1	2.1	1.1	1.1	2.0	0.9	1.2	1.0	-0.4
Ever depressed for a whole week	1.0	1.3	2.1	-1.2	-1.0	-1.4	-1.1	-0.6	-1.2	-1.5	-1.4	0.1
Commuting to job workplace: Cycle	1.0	1.2	2.9	-1.2	-1.0	-0.9	-1.5	-0.2	-0.8	-1.7	-1.5	-0.2
Rheumatoid Arthritis	0.9	1.2	3.9	1.0	0.3	1.2	0.8	-0.9	1.0	0.8	2.0	1.1
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	1.6	-1.0	-1.3	-1.0	-1.1	-1.0	-1.0	-1.0	-0.4	-1.2
Past tobacco smoking	0.9	1.7	6.1	1.1	1.5	1.5	1.0	0.9	0.9	0.1	2.5	-0.9
Fluid intelligence score	0.9	1.9	5.9	-1.2	-0.6	-1.1	-1.3	-1.0	-0.8	-2.4	-2.3	0.3
Time employed in main current job	0.9	1.1	2.4	1.0	0.9	1.2	1.1	1.6	1.2	1.2	0.2	-0.4
Supplements: Vitamin C	0.9	1.0	2.7	-0.8	-0.6	-0.9	-0.9	-1.0	-0.9	-1.3	-0.5	-1.6
Diabetes diagnosed by doctor	0.9	1.4	2.6	-1.3	-1.2	-1.4	-1.4	-1.6	-1.2	-0.5	-1.2	-0.2
Reaction Time	0.8	1.5	3.0	1.3	1.1	1.5	1.0	1.7	1.3	0.5	0.9	1.2
LDL Cholesterol	0.8	1.2	1.9	1.2	0.8	1.3	1.3	0.7	1.1	1.3	1.4	0.5
Average weekly spirits intake	0.8	1.0	2.0	-1.1	-1.4	-1.2	-0.9	-0.3	-1.0	-0.7	-1.1	-0.9
Townsend deprivation index at recruitment	0.8	1.2	2.0	-1.3	-1.2	-1.1	-1.4	-0.5	-1.1	-1.1	-1.0	0.6
Chronic bronchitis/emphysema (father)	0.8	0.9	4.6	-0.3	-0.7	-0.3	-0.0	1.1	-0.4	-1.2	-0.5	-2.1
High blood pressure (mother)	0.8	1.1	2.1	-1.2	-0.8	-1.4	-0.9	-1.2	-1.4	0.6	-0.7	-0.9
Had menopause	0.8	1.0	4.1	0.9	0.9	1.0	0.9	2.0	1.1	0.3	-0.4	-0.0
Forced vital capacity (FVC)	0.8	3.1	9.0	-1.7	-2.4	-1.9	-1.6	-3.0	-1.7	-1.1	-0.5	0.0
Happiness	0.8	1.0	2.5	-1.1	-1.6	-1.2	-0.8	-0.2	-1.0	-0.5	-1.4	0.2
Prospective memory result	0.8	1.0	3.0	-1.0	-1.2	-1.0	-0.7	-0.3	-1.0	-0.0	-0.8	-1.7
Hair/balding pattern: Pattern 4	0.8	2.0	3.0	-1.7	0.6	-1.6	-1.7	-0.6	-1.6	-1.1	-1.6	-1.5
Overall health rating	0.8	1.7	3.6	1.0	1.6	1.2	0.9	1.4	1.2	1.4	0.5	1.9
Hearing aid user	0.8	0.9	1.3	1.1	0.7	1.1	1.0	0.9	0.9	1.0	1.1	0.7
Ever smoked	0.8	1.4	5.6	-0.8	-1.3	-1.1	-0.7	-0.2	-0.5	-0.3	-2.4	1.7
Alzheimer’s Disease (in father)	0.7	0.7	1.5	0.5	0.9	0.6	0.7	0.8	0.3	1.2	1.2	0.8
Major Depression (MDD)	0.7	0.8	3.1	-0.6	-0.8	-0.6	-0.8	-0.6	-0.3	-0.9	-1.8	1.0
Type 2 Diabetes (T2D) (2018)	0.7	1.3	3.7	-1.0	-1.3	-1.1	-1.3	-1.9	-0.8	-0.5	-1.3	0.5
Severe depression (siblings)	0.7	0.8	2.5	0.3	1.6	0.5	0.0	1.1	0.5	0.8	-0.7	1.4
Number of live births	0.7	1.0	2.5	0.8	1.0	1.0	0.5	1.1	1.1	1.6	-0.1	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	3.4	-0.8	0.6	-0.7	-1.1	0.3	-0.5	-0.8	-1.8	0.9
Heart disease (mother)	0.7	0.8	2.5	0.6	1.2	0.5	0.4	0.3	0.7	1.5	-0.2	1.6
Smoking status: Previous	0.7	1.1	3.3	-0.7	-1.0	-1.1	-0.8	-1.3	-0.6	0.7	-1.8	0.8
Friendships satisfaction	0.7	0.8	1.5	-1.1	-0.5	-1.2	-0.9	-0.9	-1.1	-0.3	-1.1	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	3.6	-0.8	-1.0	-0.7	-0.8	0.2	-0.9	0.3	-0.6	-1.9
Osteoarthritis (self-reported)	0.7	0.9	1.5	1.0	1.2	1.1	0.8	1.2	1.0	0.7	0.8	0.7
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.3	-0.7	-0.6	-0.9	-0.6	-0.8	-0.7	-1.5	-1.1	-0.5
High cholesterol (Self-reported)	0.7	1.2	2.7	-1.0	-1.2	-0.9	-1.2	-1.4	-0.6	-0.6	-1.6	1.0
Medication: Paracetamol	0.7	1.1	2.6	1.3	1.0	1.1	1.3	0.4	1.3	1.6	0.2	0.5
Mean Putamen Volume	0.6	0.7	2.2	-0.7	-0.8	-0.7	-0.7	0.4	-0.7	-1.5	-0.8	-1.0
Hearing difficulty/problems: Yes	0.6	0.9	3.2	0.8	0.1	0.9	0.7	0.4	0.5	1.2	1.8	1.2
Medication: Metformin	0.6	0.9	1.9	-1.1	-1.0	-1.1	-1.1	-1.4	-1.1	-0.4	-0.3	-0.2
Stomach or abdominal pain in last month	0.6	0.8	2.4	0.6	0.7	0.4	0.8	0.5	0.1	1.5	1.5	-0.8
Hearing difficulty/problems with background noise	0.6	1.0	4.1	0.4	1.8	0.5	0.3	2.0	0.2	-0.9	0.4	-0.5
Hayfever/allergic rhinitis (self-reported)	0.6	0.9	2.8	0.9	1.7	0.6	0.8	1.4	0.9	-0.2	-0.4	-0.2
Mouth/teeth dental problems: Dentures	0.6	1.1	2.6	-1.2	-1.0	-1.0	-1.3	0.3	-1.3	-0.0	-0.2	-1.6
Pulse wave Arterial Stiffness index	0.6	0.7	2.6	0.5	0.5	0.5	0.3	1.3	0.6	-0.2	-0.5	-1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	2.0	-1.0	-0.5	-1.1	-1.1	-0.8	-0.9	-0.1	-1.4	1.2
Worry too long after embarrassment	0.6	1.0	3.6	0.8	1.0	0.9	0.7	1.9	0.8	0.6	0.3	1.1
Pulse wave peak to peak time	0.6	0.8	2.5	-0.6	-0.7	-0.6	-0.5	-1.5	-0.7	0.1	0.4	1.6
Shortness of breath walking on level ground	0.6	0.7	2.2	0.7	0.7	0.8	0.5	-0.2	0.6	1.5	1.2	0.2
Mouth/teeth dental problems: Loose teeth	0.6	0.8	3.5	0.9	0.3	0.9	0.8	1.9	0.9	0.1	0.1	0.4
Back pain experienced in last month	0.6	0.8	1.7	-1.2	-0.6	-1.0	-1.1	-0.1	-1.1	0.0	-0.7	-1.3
Illnesses of father: None of the above (group 1)	0.6	0.7	3.3	0.7	0.7	0.7	0.5	-0.6	0.9	0.7	-0.1	1.8
Guilty feelings	0.6	0.9	2.2	0.7	1.4	1.0	0.6	1.5	1.0	0.5	0.2	1.0
Ever taken oral contraceptive pill	0.6	0.6	1.4	0.5	1.2	0.5	0.3	0.5	0.9	0.5	-1.2	0.9
Medication: Atorvastatin	0.6	0.7	3.7	0.6	0.6	0.6	0.5	0.4	0.5	1.0	0.5	1.9
Unable to work because of sickness or disability	0.6	0.7	1.8	-1.2	-0.9	-0.9	-1.3	-0.4	-1.1	0.4	-0.0	0.4
Basal cell carcinoma (self-reported)	0.6	0.7	2.5	-0.9	-0.9	-0.8	-0.9	-0.4	-0.7	-1.6	-0.7	-0.4
Bipolar Disorder or Schizophrenia	0.5	1.2	2.7	-1.4	-1.1	-0.7	-1.6	-0.6	-0.9	-1.4	-0.9	-0.8
Schizophrenia (2018)	0.5	1.0	2.2	-1.0	-1.1	-0.8	-1.0	-0.4	-0.9	-1.4	-0.6	-1.5
Worry (Nagel 2018)	0.5	1.1	2.2	1.2	0.8	1.1	1.2	1.3	1.2	-0.2	0.5	1.5
Alzheimer’s Disease (in mother)	0.5	0.6	1.0	0.9	0.1	0.6	1.0	0.2	0.6	0.9	1.0	0.9
Alzheimer’s Disease (including proxy)	0.5	0.8	1.7	1.1	0.5	0.7	1.1	0.2	0.8	1.1	0.6	1.3
Schizophrenia (2014)	0.5	1.1	2.5	-1.0	-1.6	-0.7	-1.1	-1.0	-0.9	-1.2	-0.5	-1.2
Hand grip strength (left)	0.5	1.3	2.2	-1.2	-0.9	-1.3	-1.1	-1.1	-1.0	-1.2	-1.5	-0.8
Leg fat-free mass (left)	0.5	2.4	3.3	-1.8	-1.2	-1.8	-1.6	-1.6	-1.8	-1.5	-0.7	-1.6
Serious illness, injury or assault to yourself	0.5	0.5	2.5	-0.4	-0.4	-0.3	-0.2	-0.7	-0.8	0.9	1.6	0.2
Multivitamins +/- minerals	0.5	0.7	2.8	-0.2	-0.4	-0.4	-0.4	-0.9	-0.4	-1.7	-0.1	-1.3
Hair/balding pattern: Pattern 2	0.5	0.6	2.8	0.4	-0.8	0.1	0.4	-1.0	0.4	0.5	0.0	1.7
Qualifications: None of the above	0.5	1.1	2.6	0.7	0.9	1.1	0.4	1.6	0.8	0.6	1.3	1.3
Mouth/teeth dental problems	0.5	0.7	1.3	1.1	0.6	1.0	1.1	-0.6	1.1	0.3	0.8	0.5
Allergy	0.5	1.1	5.7	0.3	-0.9	0.2	0.4	-0.6	0.6	1.4	-0.8	2.4
Diabetes (self-reported)	0.5	0.8	1.7	-0.7	-1.2	-0.9	-0.8	-1.3	-0.6	-0.3	-1.2	0.1
Illnesses of siblings	0.5	0.6	1.2	1.1	0.4	1.0	1.0	0.2	1.1	0.4	0.8	-0.5
Tense / ‘highly strung’	0.5	0.8	3.1	-0.9	-0.5	-1.0	-0.6	-0.1	-1.0	-1.8	-0.6	-0.5
Comparative body size at age 10	0.5	1.3	4.8	0.9	0.6	1.0	1.1	-0.0	0.7	1.5	2.2	0.9
Number of children fathered	0.5	0.6	1.2	-0.7	-0.3	-0.5	-0.7	-0.8	-0.8	0.7	1.0	-1.1
Emphysema/chronic bronchitis	0.5	0.6	1.5	0.7	1.1	0.6	0.7	0.8	0.5	0.8	1.2	-0.2
Age at last live birth	0.5	0.7	1.6	1.1	1.0	1.1	0.8	0.4	1.3	0.6	0.1	-0.7
Family relationship satisfaction	0.5	0.6	1.3	-0.9	-1.0	-0.9	-0.6	-1.0	-1.1	-0.1	0.7	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.3	-0.8	0.0	-0.9	-0.8	-0.9	-0.7	-0.5	-1.1	-0.3
Illnesses of father: Heart disease	0.5	0.7	1.2	-1.0	-0.9	-1.0	-0.9	-0.2	-1.1	-0.6	-0.3	-0.9
Average weekly red wine intake	0.5	0.8	2.6	-0.8	-1.1	-0.7	-0.7	-0.7	-0.9	-0.7	-0.0	-1.6
Breast cancer (self-reported)	0.5	0.5	1.5	0.6	-0.1	0.5	0.4	-0.8	0.7	1.2	0.1	1.2
Medication: Aspirin	0.5	0.7	1.4	-1.1	-0.3	-1.0	-1.2	-1.1	-1.0	-0.2	-0.6	0.2
Smoking status: Current	0.5	0.8	2.3	-0.9	-1.1	-0.6	-0.9	1.0	-0.6	-0.5	-1.5	0.1
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.3	-0.8	-0.4	-0.7	-0.9	-0.3	-0.8	-1.1	-0.2	-1.1
Neuroticism (Nagel 2018)	0.4	0.9	2.8	0.6	0.9	0.9	0.8	1.5	0.8	0.3	0.2	1.7
Chronotype (morning person)	0.4	0.9	2.0	0.8	1.3	0.7	0.9	0.8	0.5	0.7	1.4	-0.9
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.2	-0.1	0.7	-0.0	-0.1	1.2	-0.1	-0.0	-0.7	-1.5
Current tobacco smoking	0.4	0.7	1.5	-0.8	-1.0	-0.5	-0.9	1.0	-0.5	-0.3	-1.2	0.6
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	1.3	-0.3	0.2	-0.2	-0.4	1.0	-0.2	-1.1	-1.1	-0.6
Supplements: Glucosamine	0.4	0.5	1.1	0.5	0.9	0.8	0.2	0.7	0.4	-0.5	1.0	-1.1
Medication: Atenolol	0.4	0.6	1.4	0.6	0.7	0.4	0.9	0.7	0.3	1.2	1.0	-0.6
Sitting height	0.4	2.6	7.5	-1.6	-2.3	-1.7	-1.3	-2.7	-1.6	-0.2	-0.5	-0.9
Leg predicted mass (left)	0.4	2.3	3.2	-1.7	-1.1	-1.7	-1.6	-1.6	-1.8	-1.6	-0.6	-1.6
Number of incorrect matches in round	0.4	0.6	2.0	0.5	0.8	0.4	0.3	0.2	0.5	1.4	-0.1	1.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.5	-0.6	-0.3	-0.8	-0.6	0.3	-0.5	-0.7	-1.6	-0.0
Impedance of arm (right)	0.4	2.1	3.1	-1.7	-1.4	-1.6	-1.8	-0.8	-1.6	-1.1	-1.5	-1.2
Impedance of arm (left)	0.4	1.7	2.3	-1.5	-1.3	-1.4	-1.5	-0.7	-1.5	-1.0	-1.4	-1.0
Standing height	0.4	4.2	6.1	-2.1	-2.5	-2.3	-1.8	-2.4	-2.1	-1.8	-1.2	-2.0
Pulse rate, automated reading	0.4	1.3	2.7	1.3	0.8	1.5	1.1	1.6	1.5	1.0	0.5	0.5
Medication: Aspirin	0.4	0.5	1.2	-0.9	-0.1	-0.8	-1.0	-1.1	-0.8	-0.0	-0.5	0.2
Leg fat-free mass (right)	0.4	2.3	3.0	-1.6	-1.3	-1.7	-1.5	-1.7	-1.7	-1.6	-0.6	-1.6
Medication for cholesterol	0.4	0.7	1.2	-1.0	-1.0	-0.9	-0.9	-1.1	-0.9	0.3	-0.4	-0.5
Leg predicted mass (right)	0.4	2.3	2.9	-1.6	-1.3	-1.7	-1.4	-1.7	-1.7	-1.6	-0.6	-1.6
Mother’s age at death	0.4	0.4	1.3	0.7	0.6	0.7	0.5	0.8	0.5	-0.1	1.1	-0.2
Commuting to job workplace: Public transport	0.4	0.5	1.7	-0.6	-1.3	-0.6	-0.5	-0.6	-0.5	-0.8	-0.9	0.0
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.3	-0.9	0.0	-0.8	-1.1	-0.9	-0.7	0.6	-0.8	-0.0
Bipolar Disorder (2018)	0.3	0.5	1.9	-0.9	-0.3	-0.2	-1.4	-0.5	-0.4	-0.5	-0.6	0.6
Schizophrenia vs Biploar Disorder	0.3	0.4	0.9	0.6	-0.1	0.1	1.0	-0.9	0.3	0.5	0.7	-0.6
Ovarian Cancer	0.3	0.4	0.9	-0.8	0.0	-0.6	-1.0	-0.5	-0.8	-0.5	-0.2	-0.9
Lupus	0.3	0.4	1.5	0.4	-0.1	0.1	0.3	0.0	0.4	-1.2	-1.0	-0.7
Neuroticism (2016)	0.3	0.5	1.8	-0.5	1.3	-0.2	-0.5	1.1	-0.4	-0.3	-0.1	-0.5
Blood White Count	0.3	1.9	4.6	1.3	1.8	1.4	1.3	2.1	1.3	1.0	0.8	-0.5
Height	0.3	5.8	10.2	-2.5	-2.6	-2.7	-2.2	-3.2	-2.4	-1.9	-1.7	-2.0
Cardiovascular Disease	0.3	1.0	1.7	-1.0	-1.0	-0.9	-0.8	-1.3	-1.2	-0.9	0.9	-0.9
Respiratory disease	0.3	0.7	2.1	0.4	0.9	0.3	0.5	1.3	-0.2	0.7	1.5	-0.9
Neuroticism	0.3	0.6	2.5	0.7	0.4	0.5	0.8	1.6	0.5	-0.6	0.3	0.9
Ever had hysterectomy (womb removed)	0.3	0.4	1.0	-0.6	-0.3	-0.5	-0.7	0.1	-0.6	-0.7	-0.5	-1.0
Qualifications: CSEs or equivalent	0.3	0.4	1.7	-0.0	-0.5	-0.4	0.1	-0.3	-0.0	-1.2	-1.3	-0.4
Hayfever, allergic rhinitis or eczema	0.3	0.7	2.8	-0.5	0.7	-0.3	-0.4	0.1	-0.7	-1.2	0.5	-1.7
Nervous feelings	0.3	0.6	2.0	0.4	0.9	0.6	0.4	1.4	0.4	-0.0	0.4	1.1
Financial difficulties in last 2 years	0.3	0.3	1.9	-0.1	0.5	0.2	-0.3	1.4	0.0	-0.2	-0.4	-0.7
Falls in the last year	0.3	0.4	0.9	-0.6	0.1	-0.2	-0.8	0.9	-0.4	-0.1	-0.3	1.0
Hair/balding pattern: Pattern 3	0.3	0.5	1.6	-0.5	-1.1	-0.3	-0.4	0.6	-0.5	-1.2	-0.2	-0.6
Pulse rate	0.3	0.5	2.3	0.2	-0.4	0.4	-0.2	1.1	0.6	0.2	-1.5	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	2.0	-0.3	-0.4	-0.2	-0.4	-0.3	-0.2	-0.9	-0.4	-1.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.6	-0.4	-0.9	-0.4	-0.1	-0.3	-0.4	0.4	-0.3	-1.3
Medication: Cholesterol lowering	0.3	0.5	2.6	-0.0	0.3	0.1	-0.2	-0.6	0.0	1.6	0.4	1.2
Illnesses of mother	0.3	0.4	0.8	0.6	0.1	0.7	0.6	0.4	0.9	-0.9	-0.2	-0.7
Length of working week for main job	0.3	0.3	1.2	0.4	-0.2	0.4	0.2	0.5	0.3	-0.7	0.3	-1.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.1	-0.1	-0.3	-0.3	-0.2	0.0	0.1	-1.5	-1.3	-0.4
Gout (self-reported)	0.3	0.4	1.1	-0.3	0.2	-0.3	-0.1	0.8	-0.1	-0.8	-1.1	-0.8
Leg fat percentage (right)	0.3	1.3	3.2	0.9	1.8	1.1	0.7	1.1	0.9	1.2	1.0	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.7	-0.3	-0.2	-0.3	-0.2	-0.5	-0.4	0.6	0.0	-1.3
Health satisfaction	0.3	0.4	2.5	0.2	-0.6	0.2	0.1	0.6	0.2	1.6	-0.0	0.1
Medication: Allopurinol	0.3	0.4	1.8	-0.5	0.3	-0.5	-0.3	0.5	-0.5	-0.6	-0.6	-1.3
Medication: Omeprazole	0.3	0.3	0.9	-0.6	-0.2	-0.5	-0.8	-0.9	-0.5	0.5	-0.3	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.9	0.3	0.1	0.4	0.1	-0.7	0.2	0.4	1.4	0.1
Asthma (self-reported)	0.3	0.5	1.3	-0.9	-0.2	-0.8	-1.1	0.3	-1.1	-0.3	-0.2	-0.5
Osteoporosis (self-reported)	0.3	0.4	1.9	-0.1	0.0	-0.3	-0.3	-0.2	0.0	-0.8	-1.4	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.7	-0.9	-0.3	-1.0	-0.6	-1.3	-1.2	-0.6	0.5	-0.6
Medication: Bendroflumethiazide	0.3	0.5	1.9	0.4	0.6	0.6	0.4	1.4	0.2	0.2	1.1	-0.4
Illnesses of father: High blood pressure	0.3	0.3	0.6	-0.5	0.1	-0.4	-0.5	-0.6	-0.7	-0.4	0.7	-0.8
Leg fat percentage (left)	0.3	1.2	2.6	1.0	1.6	1.1	0.8	0.9	1.0	1.1	0.8	1.2
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.1	-0.4	-0.7	-0.6	-0.3	-0.4	-0.4	-0.3	-1.0	-0.9
Myopia	0.3	0.5	3.1	0.5	0.3	0.6	0.3	0.2	0.7	-0.3	0.0	1.8
Intelligence (Savage-Jansen 2018)	0.2	0.5	2.9	-0.3	0.8	-0.1	-0.5	0.1	-0.1	-1.7	-0.9	0.2
Crohns Disease (2017)	0.2	0.4	2.2	0.0	-0.2	-0.0	0.1	0.5	0.1	1.5	-0.7	1.0
Irritable Bowel Disease (IBD)	0.2	0.4	1.6	-0.2	-0.6	-0.1	-0.3	0.5	-0.1	1.2	-0.4	0.9
Breast Cancer	0.2	0.6	1.8	-0.7	-0.4	-0.6	-0.6	-0.2	-0.8	-1.2	-0.1	-1.4
Systolic Blood Pressure	0.2	0.9	1.7	1.0	0.3	1.0	1.1	0.5	1.0	0.9	0.8	-1.3
Allergy or Eczema	0.2	0.6	1.5	-0.1	1.1	0.0	-0.1	1.2	-0.3	-1.0	0.6	-1.0
Tanning	0.2	3.0	5.3	-1.9	-1.5	-2.0	-2.0	-2.3	-1.6	-0.4	-1.8	-1.4
Systolic blood pressure, automated reading	0.2	0.6	1.2	0.9	0.5	0.9	1.1	0.6	0.9	1.0	0.6	-0.2
Medication for hormone replacement therapy	0.2	0.2	0.6	0.4	0.3	0.5	0.3	0.8	0.3	-0.3	0.4	-0.8
Vitamin and mineral supplements	0.2	0.3	1.2	0.2	0.4	0.2	0.4	0.8	0.2	1.1	0.1	0.6
Medication: Co-codamol	0.2	0.2	0.4	-0.5	-0.4	-0.5	-0.4	-0.4	-0.7	-0.6	0.6	0.1
Diabetes (mother)	0.2	0.2	1.1	-0.2	-0.0	-0.1	-0.2	-0.7	-0.1	0.4	0.1	1.1
Pack years adult smoking proportion	0.2	0.3	1.1	-0.7	-0.2	-0.5	-0.8	0.2	-0.3	0.1	-1.0	-0.4
Average weekly fortified wine intake	0.2	0.3	0.8	0.4	-0.3	0.1	0.8	0.4	0.1	-0.4	0.5	-0.9
High blood pressure	0.2	0.5	1.1	-0.9	-0.6	-0.8	-0.6	-0.6	-1.1	-0.3	0.7	-0.1
Heart attack	0.2	0.3	1.0	0.1	0.8	0.2	0.1	0.4	0.2	0.3	-0.5	1.0
Medication: Ramipril	0.2	0.2	0.7	0.2	-0.4	0.0	0.5	-0.9	0.1	0.5	0.7	-0.1
Medication: Simvastatin	0.2	0.3	1.6	0.0	0.2	-0.1	-0.1	-1.3	0.1	0.2	0.1	0.8
Neuroticism score	0.2	0.4	1.5	0.4	0.5	0.2	0.5	1.2	0.4	-0.8	-0.3	0.3
Trunk fat-free mass	0.2	0.9	2.2	-0.9	-0.7	-1.0	-0.8	-1.5	-1.0	-0.8	0.0	-1.2
Alcohol intake versus 10 years previously	0.2	0.3	1.2	0.4	-0.6	0.2	0.5	-0.1	0.4	0.2	-0.1	1.1
Worrier / anxious feelings	0.2	0.3	1.0	0.0	1.0	0.0	-0.1	0.6	0.3	-0.8	-1.0	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.3	0.3	1.1	0.4	-0.1	-0.2	0.4	1.1	0.3	0.2
Asthma	0.2	0.3	0.9	-0.6	-0.1	-0.5	-0.9	0.6	-0.8	-0.3	-0.0	-0.7
Medication: Lansoprazole	0.2	0.3	0.8	0.5	0.2	0.2	0.9	0.3	0.4	0.8	-0.5	-0.6
Trunk predicted mass	0.2	0.9	2.2	-0.9	-0.7	-1.0	-0.8	-1.5	-1.0	-0.7	0.0	-1.1
Breastfed as a baby	0.2	0.3	0.8	0.0	0.9	-0.1	0.2	0.7	-0.1	0.9	-0.3	0.3
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.6	0.3	0.5	0.4	0.1	0.8	0.3	-0.8	0.4	0.6
Loud music exposure frequency	0.2	0.2	0.6	0.1	-0.7	-0.1	0.5	-0.1	-0.0	-0.3	0.2	-0.7
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.8	-0.0	0.2	-0.2	-0.0	0.4	-0.0	-0.2	-0.9	0.7
Wheeze or whistling in the chest in last year	0.2	0.3	0.8	-0.5	0.0	-0.5	-0.8	0.1	-0.5	0.8	-0.9	0.1
Neck or shoulder pain in last month	0.2	0.2	1.1	-0.4	0.4	-0.1	-0.5	1.1	-0.3	0.3	0.1	-0.5
Medication: Blood pressure	0.2	0.4	2.1	-0.2	0.3	0.0	-0.1	-0.6	-0.4	1.0	1.4	0.5
Alcohol intake frequency.	0.2	0.5	1.8	-0.4	-1.0	-0.4	-0.4	0.1	-0.3	-1.3	-0.3	-0.9
Suffer from ‘nerves’	0.2	0.3	0.6	0.7	0.1	0.6	0.7	0.5	0.7	-0.4	0.4	0.7
Whole body fat-free mass	0.2	1.3	2.2	-1.2	-0.9	-1.3	-1.0	-1.5	-1.3	-1.1	-0.2	-1.3
Mood swings	0.2	0.3	1.1	0.3	0.0	0.2	0.3	1.1	0.4	-0.2	-0.7	0.9
Loneliness, isolation	0.2	0.3	0.7	-0.7	0.5	-0.4	-0.7	0.4	-0.4	-0.7	-0.8	-0.0
Ever had bowel cancer screening	0.2	0.2	0.6	0.2	0.7	0.5	-0.1	-0.2	0.4	0.6	0.8	-0.1
Commuting to job workplace: Walk	0.2	0.2	0.5	0.4	-0.4	0.3	0.4	0.3	0.6	-0.2	-0.7	0.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	0.6	0.4	0.8	0.3	0.7	0.8	0.1	0.7	0.6	-0.7
Mineral and other dietary supplements	0.2	0.3	1.9	0.2	-0.3	0.1	0.3	-0.2	0.2	1.4	-0.1	0.8
Medication: Gliclazide	0.2	0.3	0.4	-0.6	-0.7	-0.6	-0.6	-0.3	-0.6	-0.6	-0.3	-0.2
Whole body water mass	0.2	1.0	1.8	-1.0	-0.7	-1.1	-0.8	-1.4	-1.1	-1.0	-0.1	-1.1
Financial situation satisfaction	0.2	0.2	0.7	0.1	-0.8	-0.1	0.2	0.1	0.1	0.9	-0.4	0.1
Medication: Lisinopril	0.2	0.2	1.0	-0.1	0.3	0.1	-0.2	1.0	-0.1	-0.8	-0.2	-0.3
Basal metabolic rate	0.2	1.2	1.9	-1.1	-0.8	-1.2	-1.0	-1.4	-1.2	-1.1	-0.2	-1.2
Number of operations (self-reported)	0.2	0.2	0.9	0.4	0.9	0.3	0.4	0.4	0.3	0.7	0.3	-0.1
Risk taking	0.2	0.4	1.2	0.3	-0.3	0.2	0.1	-0.9	0.5	1.1	-0.5	-0.6
Fractured/broken bones in last 5 years	0.2	0.2	1.2	-0.2	0.5	-0.0	-0.3	0.3	-0.4	-0.5	1.1	-0.4
Diastolic blood pressure, automated reading	0.2	0.5	1.1	0.9	0.4	1.0	0.9	0.6	1.1	0.3	0.5	0.4
Vascular/heart problems diagnosed by doctor	0.2	0.7	1.6	1.0	0.6	0.9	0.9	0.8	1.3	0.1	-0.8	0.2
Cholesterol lowering medication	0.2	0.3	1.9	0.2	-0.1	0.1	-0.0	-0.5	0.3	-0.3	-0.8	1.4
Pain experienced in last month	0.2	0.4	2.2	0.1	-0.8	-0.1	-0.0	-0.1	0.0	-0.8	-0.5	1.5
Heart disease (siblings)	0.2	0.2	0.8	-0.4	0.4	-0.1	-0.7	0.4	0.0	0.1	-0.9	0.6
Alcohol drinker status: Previous	0.2	0.2	0.6	-0.4	-0.5	-0.4	-0.4	0.1	-0.2	-0.8	-0.6	0.5
Depressed Affect (Nagel 2018)	0.1	0.2	0.8	0.0	0.1	-0.1	0.1	0.9	0.0	-0.3	-0.6	0.7
Ulcerative Colitis (UC)	0.1	0.1	0.3	0.0	-0.6	0.2	-0.2	0.3	-0.0	0.5	0.2	0.4
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.8	0.1	0.7	0.1	-0.0	0.0	0.3	-0.5	-0.9	0.8
Crohns Disease (2012)	0.1	0.1	0.2	0.3	0.1	0.4	0.2	0.4	0.3	0.3	0.5	0.4
Primary Biliary Cirrhosis	0.1	0.2	0.5	0.3	-0.1	0.5	0.4	-0.1	0.5	0.6	0.7	-0.1
Ulcerative Colitis	0.1	0.2	0.7	-0.1	-0.4	0.1	-0.4	0.5	-0.2	0.2	0.4	0.8
Blood Eosinophil Count	0.1	0.9	2.5	-0.7	-0.5	-0.8	-0.8	1.3	-0.9	-1.6	-0.8	-0.9
Heel T-Score	0.1	0.5	1.1	-1.0	-0.5	-0.9	-1.0	-0.5	-0.9	-0.3	-0.8	0.3
Waist Hip Ratio (WHR)	0.1	0.6	2.5	-0.1	0.8	-0.1	0.0	1.0	-0.3	-1.6	0.2	-1.2
Hypothyroidism (self reported)	0.1	0.1	0.6	0.2	0.0	0.1	0.3	0.2	0.2	0.8	-0.1	0.5
Lung FEV1/FVC ratio	0.1	0.7	2.2	0.3	-0.3	-0.2	0.3	-1.2	0.5	-0.4	-1.5	1.2
Lung FVC	0.1	0.6	1.0	-0.7	-1.0	-0.7	-0.7	-0.9	-0.7	0.7	-0.3	0.9
Sensitivity / hurt feelings	0.1	0.2	0.6	-0.3	0.4	-0.5	-0.2	0.7	-0.3	-0.1	-0.8	-0.4
Angina	0.1	0.1	0.5	-0.2	0.1	-0.1	-0.3	-0.0	-0.1	0.7	-0.3	0.3
Maternal smoking around birth	0.1	0.2	0.7	-0.2	0.3	-0.2	-0.1	0.5	-0.1	0.3	-0.5	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.4	0.2	-0.0	-0.0	0.4	-0.0	-0.2	0.8	0.6	1.2
Medication: Levothyroxine sodium	0.1	0.3	0.6	-0.5	-0.6	-0.7	-0.3	0.3	-0.6	-0.0	-0.7	-0.1
Body mass index (BMI)	0.1	0.4	1.5	0.5	1.2	0.6	0.4	0.6	0.4	0.6	0.7	0.3
Impedance of leg (left)	0.1	0.6	1.2	1.0	-0.0	0.9	1.0	0.4	1.0	0.6	0.3	1.1
Waist circumference	0.1	0.4	2.0	0.5	1.4	0.5	0.5	1.0	0.4	0.1	0.4	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.9	0.4	0.4	0.1	0.5	0.1	0.1	0.8	0.5	0.9
Pulse wave reflection index	0.1	0.1	0.7	0.1	0.8	0.3	0.0	0.1	0.2	-0.4	0.4	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.9	0.4	0.3	0.4	0.4	0.9	0.4	0.4	0.1	0.3
Body fat percentage	0.1	0.3	1.3	0.3	1.1	0.4	0.2	0.7	0.2	0.5	0.3	0.6
Age at first live birth	0.1	0.1	0.5	0.3	0.4	0.3	0.2	-0.3	0.4	0.1	0.1	-0.7
Qualifications: College or University degree	0.1	0.3	0.7	0.5	0.8	0.4	0.5	0.3	0.5	0.2	-0.6	-0.8
Eye problems/disorders: None of the above	0.1	0.1	0.4	-0.2	0.6	-0.2	-0.2	0.6	-0.2	-0.2	-0.6	0.0
Medication for pain relief, constipation, heartburn	0.1	0.1	0.8	0.2	0.0	0.2	0.1	-0.1	0.3	-0.9	0.0	0.0
Angina (self-reported)	0.1	0.1	0.7	-0.2	0.1	-0.1	-0.2	-0.0	-0.2	0.9	0.0	0.3
Migraine (self-reported)	0.1	0.2	0.7	-0.3	0.1	-0.5	-0.0	0.2	-0.4	0.4	-0.8	-0.3
Medication: Ibuprofen	0.1	0.1	0.6	0.1	-0.3	0.0	0.4	-0.2	0.1	0.6	-0.0	-0.7
Leg fat mass (right)	0.1	0.4	1.8	0.5	1.3	0.5	0.4	0.6	0.5	0.6	0.4	0.6
Chest pain or discomfort	0.1	0.1	0.5	-0.1	0.3	0.1	-0.5	-0.2	-0.0	0.7	0.4	0.1
Leg pain on walking	0.1	0.2	0.4	-0.5	-0.0	-0.4	-0.5	-0.3	-0.6	0.5	0.3	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.5	0.3	0.3	0.2	0.0	0.5	0.4	0.1	-0.7	-0.2
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.4	-0.1	-0.3	-0.3	-0.1	-0.4	-0.1	-0.2	-0.4	0.7
Hypertension (Self-reported)	0.1	0.4	1.0	-0.8	-0.5	-0.7	-0.6	-0.5	-1.0	-0.2	0.8	-0.2
Arm fat percentage (left)	0.1	0.2	1.3	0.1	1.1	0.3	0.0	0.5	0.1	0.3	0.3	0.3
Miserableness	0.1	0.1	0.3	-0.3	-0.2	-0.5	-0.2	-0.1	-0.4	-0.4	-0.2	0.2
Wears glasses or contact lenses	0.1	0.2	0.4	-0.3	0.4	-0.5	0.1	0.2	-0.3	0.3	-0.5	-0.7
Medication: Blood pressure	0.1	0.1	0.6	0.0	0.1	-0.0	0.2	0.8	-0.2	-0.3	0.5	-0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.4	-0.3	-0.6	0.1	-0.4	0.1	-0.1	0.6	0.1	-0.4
Irritability	0.1	0.1	0.3	-0.2	0.1	-0.3	-0.1	0.4	-0.4	-0.3	0.4	-0.6
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.4	-0.3	0.4	-0.2	-0.3	-0.1	-0.2	-0.2	-0.6	0.6
Pack years of smoking	0.1	0.2	0.5	-0.4	0.4	-0.1	-0.6	0.6	-0.0	0.6	-0.7	-0.1
Leg fat mass (left)	0.1	0.3	1.3	0.4	1.1	0.4	0.3	0.5	0.4	0.4	0.3	0.6
BMI	0.0	0.2	1.0	-0.4	0.4	-0.3	-0.6	-0.3	-0.4	-0.3	-0.0	1.0
Hair Pigment	0.0	1.1	3.5	1.1	0.0	1.0	1.0	1.0	1.2	1.9	-0.0	1.0
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.1	0.1	-0.1	0.1	0.2	-0.1	0.1	-0.1	0.3	0.2
Impedance of leg (right)	0.0	0.2	0.6	0.5	-0.2	0.4	0.3	0.1	0.5	0.4	0.1	0.8
Trunk fat percentage	0.0	0.1	0.4	-0.3	0.6	-0.2	-0.3	0.3	-0.4	-0.1	-0.1	-0.0
Trunk fat mass	0.0	0.1	0.2	-0.3	0.5	-0.3	-0.3	0.0	-0.4	-0.2	-0.2	-0.3
Weight	0.0	0.1	0.4	-0.3	0.2	-0.4	-0.3	-0.4	-0.4	-0.3	0.1	-0.6
Arm fat percentage (right)	0.0	0.2	1.1	-0.0	1.0	0.2	-0.2	0.4	-0.0	0.2	0.3	0.2
Hip circumference	0.0	0.1	0.6	0.2	0.8	0.3	0.2	0.3	0.2	0.2	0.3	-0.3
Qualifications: A levels/AS levels or equivalent	0.0	0.1	0.3	0.1	0.3	0.2	0.2	0.5	0.1	0.0	-0.3	-0.3
Arm fat mass (right)	0.0	0.1	0.7	-0.0	0.8	0.1	-0.1	0.1	0.0	0.0	0.1	0.2
Exposure to tobacco smoke at home	0.0	0.0	0.2	0.0	-0.1	-0.1	0.1	-0.4	-0.1	0.4	-0.1	0.2
Arm fat-free mass (right)	0.0	0.2	0.7	-0.3	-0.4	-0.5	-0.1	-0.8	-0.3	-0.7	-0.0	-0.4
Whole body fat mass	0.0	0.1	0.8	0.1	0.9	0.1	0.1	0.4	0.0	0.2	0.1	0.2
Arm predicted mass (right)	0.0	0.2	0.6	-0.3	-0.2	-0.5	-0.1	-0.8	-0.4	-0.6	0.1	-0.6
Arm fat mass (left)	0.0	0.1	0.6	-0.1	0.8	0.0	-0.1	0.1	-0.1	0.1	0.3	0.1
Arm fat-free mass (left)	0.0	0.2	1.0	-0.4	-0.4	-0.5	-0.3	-1.0	-0.4	-0.5	0.2	-0.3
Impedance of whole body	0.0	0.2	0.8	-0.3	-0.9	-0.4	-0.3	-0.2	-0.3	-0.4	-0.6	0.0
Arm predicted mass (left)	0.0	0.2	0.6	-0.2	-0.2	-0.3	-0.1	-0.7	-0.3	-0.4	0.4	-0.4

Hub : Genes

F2RL1

Models

Trait associations