Best TWAS P=1.99e-22 · Best GWAS P=7.32e-36 conditioned to 1.23e-15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 9.7 | 9.7 | 2.0e-22 | -0.18 | 1.00 | 0.00 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -7.5 | -7.6 | 3.5e-14 | 0.41 | 1.00 | 0.00 | TRUE |
| 3 | YFS | Blood | MEF2C | 0.16 | 0.09 | enet | 28 | 0.12 | 5.1e-36 | -9.8 | 7.4 | 1.4e-13 | -0.83 | 1.00 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | TMEM161B | 0.03 | 0.01 | blup | 48 | 0.01 | 4.6e-02 | -5.8 | -5.2 | 1.5e-07 | 0.28 | 0.02 | 0.34 | FALSE |