Best TWAS P=1.22e-08 · Best GWAS P=8.09e-10 conditioned to 0.00247
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | PAM | 0.27 | 0.10 | lasso | 4 | 0.13 | 2.7e-04 | -6.0 | -5.2 | 1.8e-07 | 0.88 | 0.02 | 0.97 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | PPIP5K2 | 0.37 | 0.32 | enet | 22 | 0.37 | 6.6e-13 | -5.2 | -5.7 | 1.2e-08 | 0.70 | 0.50 | 0.50 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PPIP5K2 | 0.01 | 0.01 | blup | 17 | 0.01 | 9.3e-04 | -5.0 | -5.1 | 2.7e-07 | 0.68 | 0.01 | 0.87 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GIN1 | 0.08 | 0.08 | lasso | 5 | 0.09 | 3.1e-10 | -5.0 | -5.1 | 3.0e-07 | 0.60 | 0.01 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GIN1 | 0.03 | 0.03 | blup | 22 | 0.03 | 5.5e-04 | -5.0 | -5.3 | 9.0e-08 | 0.64 | 0.01 | 0.96 | FALSE |