Best TWAS P=1.23e-11 · Best GWAS P=4.39e-18 conditioned to 3.28e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | CPEB4 | 0.39 | 0.00 | lasso | 6 | 0.03 | 5.0e-02 | -8.1 | 6.6 | 5.2e-11 | 0.55 | 0.06 | 0.31 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CPEB4 | 0.10 | 0.07 | lasso | 2 | 0.06 | 1.3e-08 | -6.9 | 6.8 | 1.2e-11 | 0.55 | 1.00 | 0.00 | TRUE |
| 3 | YFS | Blood | CPEB4 | 0.58 | 0.72 | bslmm | 632 | 0.73 | 0.0e+00 | -6.9 | -6.0 | 1.5e-09 | -0.53 | 1.00 | 0.00 | FALSE |