TWAS hub - PABPC4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1530	0.0470	1.7e-06	0.042	NA	0.037	NA	0.040	2.2e-04	NA	5.4e-04	NA	3.3e-04
2	GTEx	Adrenal Gland	0.2011	0.0652	3.6e-04	0.088	NA	0.023	NA	0.062	4.7e-04	NA	5.2e-02	NA	3.0e-03
3	GTEx	Artery Tibial	0.0985	0.0343	7.7e-06	0.096	NA	0.090	NA	0.099	5.8e-08	NA	1.5e-07	NA	3.3e-08
4	GTEx	Breast Mammary Tissue	0.1290	0.0500	4.4e-04	0.017	NA	0.041	NA	0.032	4.2e-02	NA	3.4e-03	NA	9.2e-03
5	GTEx	Breast Mammary Tissue (Female)	0.0958	0.0587	4.2e-02	-0.003	NA	0.011	NA	-0.010	4.0e-01	NA	1.5e-01	NA	9.2e-01
6	GTEx	Cells Transformed fibroblasts	0.0750	0.0290	6.7e-04	0.088	NA	0.032	NA	0.060	3.8e-07	NA	1.9e-03	NA	2.7e-05
7	GTEx	Esophagus Mucosa	0.0650	0.0250	8.4e-04	0.063	NA	0.062	NA	0.077	5.0e-05	NA	6.0e-05	NA	7.3e-06
8	GTEx	Lung	0.0538	0.0242	3.0e-03	0.027	NA	0.011	NA	0.018	3.6e-03	NA	4.6e-02	NA	1.3e-02
9	GTEx	Nerve Tibial	0.1710	0.0525	7.8e-07	0.078	NA	0.047	NA	0.045	3.6e-06	NA	2.7e-04	NA	3.8e-04
10	GTEx	Skin Not Sun Exposed Suprapubic	0.1220	0.0490	1.0e-03	0.102	NA	0.007	NA	0.049	3.2e-06	NA	1.3e-01	NA	1.1e-03
11	GTEx	Skin Sun Exposed Lower leg	0.1130	0.0390	5.5e-06	0.092	NA	0.076	NA	0.082	4.5e-08	NA	6.9e-07	NA	2.7e-07
12	GTEx	Thyroid	0.0830	0.0330	3.6e-04	0.034	NA	0.038	NA	0.048	1.2e-03	NA	6.9e-04	NA	1.3e-04
13	METSIM	Adipose	0.0483	0.0197	5.7e-05	0.025	0.023	0.023	0.022	0.027	9.8e-05	1.9e-04	2.1e-04	2.3e-04	6.0e-05
14	NTR	Blood	0.0102	0.0054	1.8e-02	0.005	0.003	0.001	0.003	0.003	9.2e-03	2.8e-02	1.3e-01	4.2e-02	3.5e-02
15	YFS	Blood	0.0441	0.0143	1.8e-08	0.031	0.028	0.034	0.033	0.029	1.8e-10	1.6e-09	3.2e-11	6.4e-11	6.8e-10
16	TCGA	Breast Invasive Carcinoma	0.0326	0.0172	2.1e-06	0.030	0.023	0.025	NA	0.039	5.8e-07	1.4e-05	4.7e-06	NA	1.3e-08
17	TCGA	Cervical Squamous Cell Carcinoma	0.0660	0.0400	4.3e-03	0.019	0.043	0.027	NA	0.033	3.9e-02	3.3e-03	1.6e-02	NA	9.1e-03
18	TCGA	Head and Neck Squamous Cell Carcinoma	0.0261	0.0152	2.8e-03	0.011	0.012	0.017	NA	0.014	1.9e-02	1.6e-02	4.3e-03	NA	8.5e-03
19	TCGA	Kidney Renal Clear Cell Carcinoma	0.0388	0.0215	1.0e-04	0.049	0.043	0.040	NA	0.040	3.3e-06	1.2e-05	2.2e-05	NA	2.4e-05
20	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0510	0.0290	2.2e-03	0.051	0.041	0.053	NA	0.047	6.9e-04	2.2e-03	5.5e-04	NA	1.0e-03
21	TCGA	Brain Lower Grade Glioma	0.0165	0.0105	9.8e-03	0.010	0.017	0.011	NA	0.011	2.1e-02	4.7e-03	1.7e-02	NA	1.7e-02
22	TCGA	Lung Adenocarcinoma	0.0434	0.0245	2.5e-04	0.032	0.031	0.036	NA	0.033	1.1e-04	1.4e-04	4.5e-05	NA	7.9e-05
23	TCGA	Prostate Adenocarcinoma	0.1367	0.0602	1.7e-07	0.029	0.060	0.076	NA	0.058	4.8e-04	6.7e-07	2.3e-08	NA	1.1e-06
24	TCGA	Thyroid Carcinoma	0.0900	0.0370	4.6e-06	0.065	0.074	0.079	NA	0.072	6.2e-07	1.2e-07	4.1e-08	NA	1.5e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
HDL Cholesterol	19.1	31.9	43.0	6.1	6.4	6.2	5.8	4.9	6.0	6.5	5.5	5.4	6.3	6.6	4.8	6.2	5.0	6.3	5.0	4.4	6.0	4.8	5.7	4.7	5.6	4.6	5.9
Type 2 Diabetes (T2D) (2018)	18.2	34.1	41.6	-5.6	-6.2	-6.4	-5.7	-4.7	-6.3	-6.4	-6.2	-5.9	-6.2	-6.2	-4.7	-5.9	-4.4	-5.4	-6.2	-5.4	-6.3	-6.2	-5.8	-5.6	-6.5	-5.2	-6.0
Pain experienced in last month	14.4	23.9	36.3	4.9	6.0	5.2	5.1	5.0	5.2	5.3	4.8	4.5	5.3	5.5	5.1	5.2	5.7	4.3	4.8	3.3	4.9	4.7	4.6	3.7	4.8	3.2	5.2
Lung FEV1/FVC ratio	14.3	72.4	93.5	9.0	8.7	9.1	9.1	6.8	8.9	9.1	8.4	8.7	9.0	9.6	7.5	8.9	9.7	9.2	7.7	7.8	8.8	7.2	9.0	8.1	8.3	7.5	7.3
Alcohol intake versus 10 years previously	13.3	19.9	26.2	-3.8	-4.8	-4.6	-5.1	-4.6	-4.5	-4.8	-4.7	-4.9	-4.6	-4.6	-3.0	-4.6	-4.8	-3.5	-5.0	-4.0	-4.4	-4.9	-4.6	-4.2	-4.6	-3.7	-4.2
Diabetes diagnosed by doctor	12.5	20.5	26.3	-4.4	-4.9	-5.1	-4.7	-3.8	-5.0	-4.8	-4.9	-4.9	-4.6	-4.6	-3.7	-4.6	-3.1	-3.8	-4.8	-4.4	-4.8	-4.5	-4.4	-4.5	-4.9	-4.3	-4.3
Triglycerides	11.9	19.4	29.6	-4.6	-5.0	-5.1	-4.5	-3.5	-5.0	-5.0	-4.4	-4.4	-4.9	-5.1	-3.8	-4.4	-3.7	-5.4	-4.0	-3.5	-4.6	-2.9	-4.6	-4.0	-4.1	-4.4	-3.6
Diabetes (self-reported)	11.6	17.8	21.7	-4.3	-4.3	-4.7	-4.3	-3.6	-4.4	-4.4	-4.5	-4.6	-4.2	-4.3	-3.5	-4.4	-3.0	-3.8	-4.3	-4.3	-4.5	-4.0	-4.3	-4.5	-4.5	-4.5	-3.8
Neck or shoulder pain in last month	11.6	16.5	21.4	-4.4	-4.6	-4.3	-4.2	-3.8	-4.2	-4.1	-4.3	-4.6	-4.1	-4.3	-4.1	-4.4	-3.2	-2.8	-4.1	-3.7	-4.1	-4.0	-4.1	-4.1	-4.0	-3.8	-3.7
Leg fat-free mass (left)	11.5	60.9	93.3	-7.4	-9.7	-8.1	-7.9	-8.9	-8.2	-8.5	-7.5	-7.9	-8.5	-8.2	-7.2	-7.4	-9.4	-6.5	-8.1	-5.2	-7.9	-7.8	-7.1	-5.7	-8.0	-5.8	-8.7
Leg fat-free mass (right)	11.4	60.9	92.9	-7.4	-9.6	-8.1	-7.9	-8.8	-8.2	-8.5	-7.5	-7.7	-8.5	-8.3	-7.1	-7.4	-9.6	-6.6	-8.1	-5.2	-7.9	-7.8	-7.1	-5.7	-8.0	-5.7	-8.8
Leg predicted mass (left)	11.3	59.8	91.8	-7.4	-9.6	-8.0	-7.8	-8.8	-8.1	-8.4	-7.4	-7.8	-8.4	-8.2	-7.1	-7.3	-9.4	-6.4	-8.0	-5.2	-7.8	-7.7	-7.0	-5.6	-7.9	-5.7	-8.6
Leg predicted mass (right)	11.2	59.6	91.6	-7.3	-9.6	-8.0	-7.8	-8.7	-8.1	-8.4	-7.4	-7.6	-8.4	-8.2	-7.1	-7.4	-9.6	-6.5	-8.0	-5.1	-7.8	-7.8	-7.0	-5.6	-7.9	-5.6	-8.7
Impedance of leg (left)	10.6	51.5	88.0	6.8	9.4	7.5	7.2	8.9	7.7	7.5	7.2	7.2	7.4	7.2	7.0	6.3	8.4	4.2	8.1	4.2	7.2	8.1	5.8	4.5	7.5	4.5	9.0
Medication: Metformin	9.9	14.0	16.6	-3.7	-3.8	-4.0	-3.8	-3.6	-3.8	-3.9	-4.1	-3.7	-3.9	-3.9	-3.4	-3.9	-3.4	-3.3	-3.8	-3.7	-3.8	-3.8	-3.8	-3.8	-4.0	-3.2	-3.4
Waist circumference	9.6	35.2	51.0	-5.7	-7.1	-6.2	-6.4	-6.8	-6.3	-6.3	-5.9	-6.2	-6.4	-6.2	-5.0	-5.3	-6.2	-5.0	-6.2	-4.3	-6.1	-5.9	-5.5	-4.7	-6.3	-4.8	-6.5
Impedance of leg (right)	9.4	45.4	78.7	6.3	8.9	6.9	6.6	8.1	7.2	7.1	6.7	6.4	7.0	6.8	6.4	6.0	8.4	4.0	7.6	3.7	6.8	7.8	5.4	4.0	7.1	3.9	8.8
Long-standing illness, disability or infirmity	9.4	14.4	23.1	-3.1	-4.0	-4.0	-3.9	-2.1	-4.0	-4.0	-4.4	-4.1	-3.9	-3.7	-2.8	-3.3	-2.7	-2.8	-4.7	-3.9	-3.8	-4.8	-4.0	-4.0	-4.2	-3.4	-3.9
Pulse rate, automated reading	8.9	28.8	40.7	-5.0	-6.4	-5.9	-5.4	-5.0	-5.8	-5.9	-5.7	-5.2	-5.8	-5.7	-4.7	-5.5	-5.7	-4.6	-5.8	-4.2	-5.5	-5.8	-5.0	-4.4	-5.7	-3.4	-5.8
Knee pain experienced in last month	8.8	13.6	23.2	-3.4	-4.4	-3.9	-3.4	-3.1	-4.1	-4.0	-3.7	-3.3	-4.1	-4.0	-3.3	-3.4	-4.8	-3.9	-3.8	-2.7	-3.9	-3.8	-3.5	-2.7	-3.5	-1.8	-4.6
Financial difficulties in last 2 years	8.7	11.7	21.1	-3.4	-4.6	-3.5	-3.7	-3.8	-3.7	-3.9	-3.2	-2.9	-4.0	-3.7	-2.4	-3.5	-3.5	-2.7	-3.4	-1.7	-3.5	-3.4	-3.0	-2.2	-3.9	-2.4	-4.6
Frequency of tiredness / lethargy in last 2 weeks	8.1	13.2	18.1	-2.8	-4.0	-4.0	-4.2	-2.6	-4.2	-4.1	-3.7	-3.5	-4.1	-4.1	-1.0	-3.4	-2.9	-3.5	-4.0	-3.0	-4.3	-3.9	-3.9	-3.1	-3.8	-3.3	-4.0
Illness, injury, bereavement, stress in last 2 years	7.8	9.6	15.3	3.0	3.7	3.2	3.3	3.2	3.3	3.2	3.2	2.8	3.2	2.9	3.0	2.3	3.9	2.4	3.4	2.0	3.0	3.4	2.6	2.4	3.8	2.3	3.6
Diabetes (mother)	7.7	9.9	13.7	-3.6	-3.6	-3.3	-3.1	-3.6	-3.0	-3.5	-2.9	-3.1	-3.3	-3.7	-2.9	-3.4	-3.5	-3.4	-3.0	-2.6	-2.9	-3.0	-3.1	-2.6	-3.0	-2.4	-2.6
Weight	7.4	36.5	56.9	-5.6	-7.5	-6.2	-6.3	-7.5	-6.2	-6.4	-5.7	-6.2	-6.5	-6.2	-5.5	-5.8	-7.5	-5.0	-6.3	-3.9	-6.0	-5.9	-5.3	-4.3	-6.3	-4.6	-6.8
Arm fat mass (right)	7.2	29.7	48.4	-5.0	-7.0	-5.5	-5.8	-6.8	-5.7	-5.8	-5.1	-5.4	-5.9	-5.6	-5.0	-5.4	-6.2	-4.7	-5.6	-3.2	-5.5	-5.2	-4.7	-3.6	-5.7	-4.2	-6.5
Headache pain in last month	7.2	12.4	19.5	-3.9	-4.3	-4.0	-3.7	-3.6	-3.8	-3.7	-3.3	-4.4	-3.3	-3.8	-3.4	-3.7	-3.6	-3.5	-3.1	-2.8	-3.6	-2.6	-3.1	-2.9	-3.0	-3.4	-3.1
BMI	7.1	40.9	69.9	-5.8	-8.4	-6.5	-6.6	-8.2	-6.8	-6.8	-6.2	-6.3	-6.9	-6.3	-5.7	-6.1	-6.6	-4.5	-7.1	-3.3	-6.3	-6.9	-5.2	-4.0	-7.3	-5.1	-7.9
Respiratory disease	6.8	15.0	19.4	-4.2	-4.1	-4.3	-3.9	-3.4	-4.3	-4.1	-3.8	-3.6	-4.0	-4.3	-2.7	-4.2	-4.1	-4.4	-3.4	-3.4	-4.2	-3.3	-3.9	-3.6	-3.7	-3.7	-3.7
Basal metabolic rate	6.8	37.5	63.5	-5.8	-7.7	-6.3	-6.2	-7.5	-6.3	-6.6	-5.7	-6.2	-6.7	-6.4	-5.7	-5.8	-8.0	-5.0	-6.3	-3.8	-6.1	-6.0	-5.4	-4.2	-6.2	-4.4	-6.8
Overall health rating	6.7	14.3	20.9	-2.9	-4.6	-4.3	-4.1	-2.4	-4.6	-4.2	-4.1	-3.9	-4.1	-3.8	-2.0	-3.4	-2.6	-3.3	-4.4	-3.0	-4.4	-4.1	-3.7	-3.1	-4.2	-3.4	-4.6
Back pain experienced in last month	6.7	9.8	12.9	-3.6	-3.0	-3.4	-3.4	-2.3	-3.3	-3.4	-3.5	-2.8	-3.5	-3.6	-2.8	-2.8	-1.7	-2.9	-3.0	-3.4	-3.4	-3.4	-3.5	-3.5	-3.1	-2.1	-2.8
Trunk fat mass	6.5	28.1	42.8	-4.8	-6.5	-5.5	-5.7	-6.2	-5.5	-5.6	-5.1	-5.3	-5.8	-5.5	-4.6	-5.3	-5.9	-5.1	-5.3	-3.5	-5.4	-4.9	-4.8	-4.0	-5.6	-4.6	-5.9
Arm fat mass (left)	6.5	26.7	44.7	-4.8	-6.7	-5.2	-5.5	-6.6	-5.4	-5.5	-4.8	-5.1	-5.6	-5.4	-4.8	-5.1	-6.0	-4.4	-5.2	-2.9	-5.1	-4.9	-4.3	-3.3	-5.4	-3.9	-6.2
Medication: Ramipril	6.3	8.0	11.5	-3.4	-2.5	-3.3	-2.6	-1.3	-3.2	-3.1	-3.2	-3.1	-3.0	-3.1	-1.3	-2.7	-1.2	-2.5	-2.7	-3.1	-3.2	-2.6	-3.2	-3.3	-3.2	-3.2	-2.3
Average weekly fortified wine intake	6.2	7.3	12.5	2.8	3.0	2.9	2.6	1.8	3.0	2.9	2.8	2.4	2.8	2.7	2.2	3.5	2.6	2.1	2.7	2.6	3.0	2.4	3.0	2.8	2.8	2.5	2.3
Hip circumference	6.2	26.7	41.0	-4.9	-6.4	-5.3	-5.4	-6.3	-5.4	-5.5	-5.1	-5.1	-5.5	-5.1	-4.9	-4.6	-6.2	-3.6	-5.6	-3.6	-5.2	-5.2	-4.5	-3.9	-5.5	-4.3	-5.7
Prostate Cancer	6.1	8.6	13.5	-2.6	-3.3	-3.0	-3.4	-3.7	-2.7	-3.1	-2.7	-2.9	-3.2	-2.6	-3.3	-3.2	-2.7	-2.8	-2.9	-2.8	-2.8	-2.4	-2.8	-3.1	-2.7	-3.0	-2.7
Arm fat percentage (right)	6.1	24.1	39.2	-4.3	-6.3	-5.0	-5.2	-5.7	-5.2	-5.2	-4.7	-4.8	-5.4	-5.1	-4.3	-5.0	-5.0	-4.6	-5.1	-3.0	-5.1	-4.7	-4.2	-3.4	-5.3	-4.1	-6.0
Alcohol intake frequency.	6.1	14.2	19.5	-3.2	-4.4	-4.0	-3.9	-3.4	-3.9	-3.9	-4.1	-3.9	-3.8	-3.7	-3.6	-4.0	-3.8	-2.2	-4.4	-3.1	-3.5	-4.3	-3.3	-3.2	-4.2	-3.6	-4.3
Whole body fat-free mass	6.0	34.5	60.8	-5.7	-7.3	-6.0	-5.8	-7.1	-6.0	-6.4	-5.5	-6.0	-6.4	-6.2	-5.5	-5.6	-7.8	-4.8	-6.0	-3.7	-5.8	-5.8	-5.2	-4.0	-5.9	-4.1	-6.4
Whole body water mass	5.8	33.1	59.3	-5.6	-7.2	-5.9	-5.8	-7.2	-5.9	-6.2	-5.4	-5.9	-6.2	-6.0	-5.5	-5.4	-7.7	-4.6	-5.9	-3.6	-5.6	-5.6	-5.1	-3.9	-5.8	-4.0	-6.2
Qualifications: CSEs or equivalent	5.7	7.5	12.0	-2.6	-2.9	-2.6	-2.9	-2.3	-2.5	-3.0	-2.4	-2.6	-3.0	-2.9	-2.1	-3.1	-3.5	-3.1	-2.6	-2.3	-2.7	-2.7	-3.0	-2.6	-2.7	-2.7	-2.7
Mother’s age at death	5.6	7.0	14.8	2.2	3.0	3.2	2.4	1.1	2.9	2.9	3.0	3.9	2.7	3.0	1.6	2.5	1.5	2.6	2.9	3.0	2.7	2.4	3.1	2.9	2.2	2.7	1.6
Arm fat percentage (left)	5.5	22.1	37.7	-4.2	-6.1	-4.8	-5.0	-5.8	-5.0	-5.0	-4.4	-4.5	-5.2	-4.8	-4.3	-4.8	-4.9	-4.2	-4.8	-2.6	-4.8	-4.4	-4.0	-3.1	-5.0	-3.8	-5.9
Whole body fat mass	5.4	22.7	37.8	-4.2	-6.1	-4.9	-5.0	-5.6	-5.0	-5.1	-4.4	-4.7	-5.2	-4.9	-4.1	-4.6	-5.5	-4.3	-4.8	-2.8	-4.9	-4.5	-4.1	-3.3	-5.0	-4.0	-5.8
Body mass index (BMI)	5.3	22.5	42.5	-4.1	-6.5	-4.8	-4.9	-6.3	-5.1	-5.0	-4.4	-4.5	-5.1	-4.6	-4.2	-4.5	-5.7	-3.2	-5.1	-2.2	-4.8	-4.9	-3.6	-2.6	-5.1	-3.3	-6.5
Loud music exposure frequency	5.1	5.5	8.9	-2.0	-2.8	-2.8	-1.9	-0.8	-3.0	-2.6	-2.5	-1.6	-2.7	-2.4	-1.0	-2.5	-2.9	-2.5	-2.4	-2.0	-2.9	-2.1	-2.4	-1.8	-2.4	-1.6	-2.9
Had menopause	5.0	6.3	10.4	2.3	3.1	2.8	2.1	1.7	2.9	2.8	2.4	2.3	2.9	2.6	1.5	2.4	2.8	3.2	2.2	1.9	2.9	1.9	2.4	1.9	2.3	2.8	3.0
Wheeze or whistling in the chest in last year	5.0	8.8	12.8	-3.0	-3.5	-3.4	-3.2	-2.1	-3.6	-3.2	-3.2	-3.1	-3.4	-3.6	-1.8	-2.7	-2.8	-3.0	-2.9	-2.3	-3.0	-2.6	-3.2	-2.6	-3.1	-2.4	-2.8
Trunk fat percentage	4.9	19.5	28.8	-4.0	-5.4	-4.6	-4.8	-4.9	-4.6	-4.7	-4.2	-4.4	-4.8	-4.5	-3.7	-4.5	-4.4	-4.6	-4.3	-3.1	-4.6	-3.9	-4.1	-3.5	-4.7	-4.2	-4.9
Crohns Disease (2012)	4.8	7.7	13.1	-3.3	-3.0	-3.0	-2.6	-2.5	-3.1	-2.9	-2.8	-2.1	-2.8	-3.0	-2.2	-2.6	-3.6	-3.0	-2.4	-2.0	-2.9	-2.2	-2.5	-2.4	-3.0	-3.1	-2.8
Exposure to tobacco smoke outside home	4.7	6.3	9.6	-2.1	-2.8	-2.5	-2.6	-1.9	-2.5	-2.8	-2.7	-2.4	-2.9	-2.4	-1.8	-2.5	-1.8	-2.1	-3.0	-2.2	-2.5	-3.1	-2.6	-2.3	-3.1	-2.2	-2.7
Number of full brothers	4.7	5.9	9.6	-3.0	-2.8	-2.5	-2.4	-3.1	-2.4	-2.9	-2.2	-2.4	-2.8	-2.8	-1.9	-2.3	-1.4	-2.3	-2.1	-1.7	-2.5	-2.1	-2.4	-2.1	-2.6	-2.3	-2.3
Illnesses of siblings	4.6	6.5	8.2	2.9	2.7	2.7	2.4	2.5	2.6	2.7	2.8	2.6	2.6	2.7	2.3	2.6	1.0	2.1	2.8	2.7	2.6	2.5	2.7	2.8	2.9	2.4	2.1
Illnesses of mother	4.6	5.7	10.2	2.4	3.2	2.5	2.3	2.1	2.6	2.3	2.3	2.0	2.2	2.3	3.1	2.3	2.9	1.7	2.5	1.7	2.5	2.5	1.9	1.8	2.5	1.7	3.0
HbA1C	4.5	5.0	8.1	-2.6	-2.3	-2.3	-1.6	-1.1	-2.2	-2.6	-2.3	-1.8	-2.5	-2.9	-2.3	-2.6	-2.4	-2.0	-2.2	-1.8	-2.2	-2.2	-2.6	-2.0	-2.7	-1.9	-1.7
Cardiovascular Disease	4.5	14.7	20.9	-4.0	-4.1	-4.3	-4.1	-3.7	-4.1	-4.3	-3.7	-4.0	-4.2	-4.2	-2.1	-3.8	-2.1	-4.6	-3.6	-3.3	-4.1	-3.1	-4.1	-3.7	-4.0	-4.2	-3.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.4	9.4	16.1	3.1	3.2	3.3	2.8	1.8	3.2	3.5	2.8	2.7	3.5	3.5	2.1	3.3	3.3	3.3	2.5	2.7	3.4	2.1	3.4	3.1	3.3	4.0	2.6
Number of self-reported non-cancer illnesses	4.4	7.6	11.0	-2.8	-3.2	-3.1	-2.7	-1.7	-3.3	-2.9	-2.9	-2.7	-2.8	-3.2	-1.3	-2.4	-2.3	-2.6	-2.8	-2.2	-3.1	-2.8	-2.7	-2.3	-3.2	-2.7	-3.3
High blood pressure (mother)	4.3	6.1	11.8	-2.7	-2.9	-2.4	-2.7	-3.3	-2.2	-2.4	-2.1	-2.5	-2.1	-2.4	-3.4	-3.2	-2.8	-2.0	-2.3	-2.0	-2.2	-2.4	-2.1	-2.0	-2.1	-1.4	-2.1
Chest pain or discomfort	4.2	6.1	9.4	-3.0	-3.1	-2.6	-2.4	-1.9	-2.8	-2.4	-2.6	-2.5	-2.4	-3.0	-2.0	-2.4	-3.0	-2.3	-2.6	-1.8	-2.2	-2.7	-2.4	-1.9	-2.5	-2.0	-2.3
Medication: Blood pressure	4.2	8.0	12.5	-2.3	-2.9	-3.2	-3.0	-1.8	-3.2	-2.9	-3.4	-2.9	-2.8	-2.6	-1.9	-1.9	-1.6	-2.5	-3.5	-2.9	-3.0	-3.3	-2.9	-3.1	-3.5	-2.9	-2.6
Peak expiratory flow (PEF)	4.0	9.3	12.8	3.2	2.8	3.6	3.3	1.5	3.5	3.1	3.6	2.7	3.1	3.2	2.8	2.7	1.6	2.7	3.1	3.5	3.4	2.6	3.3	3.6	3.4	3.6	2.2
Fasting Glucose	3.9	4.7	8.9	-2.3	-2.8	-2.2	-2.0	-2.7	-2.1	-2.4	-1.7	-1.8	-2.1	-2.3	-3.0	-2.8	-2.8	-2.4	-1.8	-0.8	-1.8	-1.8	-1.6	-1.1	-2.4	-1.6	-2.2
Mouth/teeth dental problems: Dentures	3.9	6.6	11.1	1.9	2.8	2.7	2.5	1.4	2.7	2.5	2.9	2.8	2.3	2.1	1.9	2.0	3.0	1.4	3.3	2.5	2.8	3.2	2.6	2.8	2.9	2.7	2.6
Ovarian Cancer	3.8	5.1	8.3	-2.2	-2.4	-2.4	-1.4	-1.8	-2.2	-2.7	-2.0	-2.4	-2.7	-2.5	-1.6	-2.1	-2.1	-2.9	-2.0	-1.6	-2.6	-2.1	-2.2	-1.9	-2.6	-2.3	-2.6
Diabetes (father)	3.8	4.7	7.2	-2.3	-2.1	-2.3	-2.3	-1.7	-2.1	-2.0	-2.4	-2.4	-1.7	-1.8	-2.4	-2.2	-1.5	-0.9	-2.6	-2.4	-2.0	-2.7	-2.1	-2.4	-2.6	-2.5	-1.5
Heart attack	3.8	4.8	10.6	-2.5	-2.4	-2.6	-2.1	-1.3	-2.6	-2.3	-2.3	-2.2	-2.3	-2.3	-0.7	-2.3	-1.8	-2.0	-2.1	-1.8	-2.3	-1.7	-2.2	-2.1	-2.4	-3.2	-1.8
Trunk fat-free mass	3.8	21.7	43.4	-4.6	-5.8	-4.8	-4.6	-6.1	-4.7	-5.0	-4.3	-5.0	-5.0	-4.8	-4.6	-4.3	-6.6	-3.5	-4.8	-2.9	-4.4	-4.5	-4.0	-3.1	-4.6	-3.1	-4.9
Ever taken oral contraceptive pill	3.8	4.3	11.6	-1.4	-3.2	-2.5	-1.4	-0.9	-2.7	-2.3	-2.2	-1.8	-1.9	-2.1	-1.8	-1.6	-2.0	-1.8	-2.6	-0.7	-2.3	-2.6	-1.3	-0.7	-2.2	-1.0	-3.4
Diastolic blood pressure, automated reading	3.8	11.8	18.8	-2.8	-4.3	-3.6	-3.4	-2.8	-3.8	-3.8	-3.5	-3.5	-3.8	-3.9	-4.0	-3.6	-3.4	-2.9	-3.9	-2.5	-3.5	-3.4	-3.2	-2.4	-3.4	-1.8	-4.1
LDL Cholesterol	3.7	5.9	8.3	-2.5	-2.2	-2.6	-2.7	-2.2	-2.6	-2.8	-2.4	-2.2	-2.7	-2.7	-1.3	-2.3	-2.5	-2.7	-2.2	-2.0	-2.9	-2.4	-2.6	-2.1	-2.6	-1.7	-2.6
Depression (self-reported)	3.7	4.4	9.3	-1.6	-2.3	-2.3	-2.6	-1.7	-2.3	-2.1	-2.3	-2.9	-1.8	-2.1	-1.2	-1.3	-0.0	-1.8	-2.4	-1.7	-2.4	-3.0	-1.9	-1.8	-2.2	-1.2	-2.9
Leg fat mass (left)	3.7	14.3	27.2	-3.1	-5.2	-3.8	-3.9	-4.8	-4.0	-4.0	-3.3	-3.6	-4.2	-3.8	-3.3	-3.8	-4.6	-3.2	-3.8	-1.7	-3.9	-3.6	-3.0	-2.1	-4.1	-3.0	-5.2
Type 2 Diabetes (T2D) (2012)	3.6	4.1	8.6	-1.8	-2.4	-1.9	-2.0	-2.4	-1.7	-2.5	-1.2	-1.6	-2.5	-2.4	-1.9	-2.4	-2.9	-2.8	-1.4	-1.0	-1.9	-1.5	-2.0	-1.2	-2.1	-1.7	-2.2
Trunk predicted mass	3.6	20.3	41.7	-4.4	-5.7	-4.6	-4.4	-6.0	-4.5	-4.8	-4.2	-4.8	-4.8	-4.7	-4.5	-4.2	-6.5	-3.4	-4.7	-2.8	-4.2	-4.4	-3.8	-2.9	-4.4	-2.9	-4.7
Medication: Ventolin 100micrograms inhaler	3.6	4.7	7.2	-2.2	-2.1	-2.5	-2.2	-1.5	-2.7	-2.2	-2.4	-2.4	-2.1	-2.4	-1.3	-2.1	-2.3	-1.6	-2.2	-2.2	-2.6	-2.0	-2.3	-2.1	-1.9	-1.6	-2.1
High blood pressure (siblings)	3.6	5.2	6.7	-2.4	-2.5	-2.5	-2.3	-2.4	-2.4	-2.5	-2.4	-2.4	-2.4	-2.6	-2.2	-2.6	-0.3	-2.5	-2.3	-2.1	-2.2	-1.7	-2.4	-2.2	-2.3	-2.3	-1.6
Age started oral contraceptive pill	3.6	4.5	11.5	1.6	2.4	2.3	1.8	0.8	2.5	2.5	1.5	1.9	2.7	2.6	-0.5	2.8	1.8	3.4	1.2	0.8	2.6	1.3	2.2	1.1	2.1	2.8	2.7
Medication: Omeprazole (e.g. Zanprol)	3.6	4.4	8.3	-1.7	-2.6	-2.6	-1.7	-0.5	-2.6	-2.1	-2.9	-1.9	-1.8	-2.0	-1.5	-1.0	-1.3	-1.3	-2.9	-2.1	-2.2	-2.8	-1.8	-2.2	-2.4	-2.3	-2.3
Leg fat mass (right)	3.5	13.7	26.0	-3.0	-5.1	-3.7	-3.8	-4.8	-3.9	-3.9	-3.2	-3.7	-4.1	-3.6	-3.3	-3.6	-4.4	-3.0	-3.8	-1.7	-3.8	-3.5	-2.8	-2.1	-4.0	-3.0	-5.0
Heart attack/myocardial infarction (self-reported)	3.5	4.5	10.6	-2.5	-2.4	-2.5	-2.1	-1.4	-2.5	-2.2	-2.2	-2.1	-2.2	-2.2	-0.7	-2.1	-1.6	-2.0	-2.0	-1.8	-2.2	-1.5	-2.0	-2.0	-2.2	-3.3	-1.8
Number of treatments/medications taken	3.4	6.1	10.6	-2.0	-3.2	-2.9	-2.3	-1.7	-3.0	-2.6	-2.7	-2.2	-2.5	-2.7	-1.2	-2.5	-2.1	-1.9	-3.0	-1.7	-2.6	-2.9	-2.1	-1.8	-3.0	-2.3	-3.2
Allergy	3.4	7.9	12.0	2.8	3.1	3.1	2.9	3.5	3.1	2.9	2.8	2.6	2.6	2.7	2.8	2.8	3.4	2.1	3.0	2.5	3.1	2.9	2.6	2.5	2.5	1.8	2.9
Pulse rate	3.4	5.7	11.1	-2.2	-3.1	-2.7	-2.2	-1.6	-2.7	-2.8	-2.4	-1.9	-2.8	-2.6	-1.6	-2.9	-2.3	-2.2	-2.4	-1.4	-2.7	-2.8	-2.0	-1.5	-2.6	-0.8	-3.3
Hair/balding pattern: Pattern 4	3.4	8.2	14.7	2.7	3.4	3.0	2.8	3.3	2.9	3.0	2.8	2.5	2.9	2.9	3.5	2.7	3.8	2.6	2.9	2.2	2.8	2.6	2.5	2.4	2.7	2.2	2.9
Pain type(s) experienced in last month: Hip pain	3.4	4.3	7.6	-2.2	-2.7	-2.3	-2.2	-1.8	-2.4	-2.3	-2.2	-2.1	-2.3	-2.6	-1.9	-2.0	-2.8	-1.6	-2.2	-1.6	-2.0	-1.9	-2.2	-1.6	-1.7	-1.0	-1.5
Schizophrenia vs Biploar Disorder	3.3	4.4	7.5	2.3	2.1	2.1	2.5	2.6	1.7	2.4	1.8	2.7	2.3	2.3	2.6	1.8	1.5	2.3	1.8	1.9	1.8	1.7	2.2	2.1	2.0	1.9	1.4
Medication for cholesterol	3.3	5.0	8.0	1.5	2.1	2.4	2.3	1.1	2.3	2.4	2.5	2.3	2.3	2.1	1.4	1.6	1.2	1.6	2.8	2.5	2.4	2.8	2.5	2.6	2.8	2.4	2.2
Hypothyroidism (self reported)	3.2	7.3	10.5	2.8	2.5	2.8	2.5	2.8	2.6	2.7	3.2	2.2	2.7	2.6	2.6	2.6	3.0	1.5	3.2	3.0	2.5	3.2	2.6	3.1	3.0	2.5	2.2
Birth weight	3.2	6.9	13.5	3.4	1.9	2.7	2.0	1.9	2.2	2.8	2.9	3.0	2.6	2.7	3.0	1.4	1.7	2.5	2.5	3.7	2.5	2.8	3.2	3.6	2.6	2.1	1.2
Body fat percentage	3.2	12.8	21.6	-3.0	-4.7	-3.6	-3.9	-4.3	-3.8	-3.8	-3.3	-3.4	-4.0	-3.6	-3.1	-3.7	-3.8	-3.5	-3.6	-2.1	-3.7	-3.2	-3.1	-2.5	-3.9	-3.4	-4.4
Arm predicted mass (left)	3.2	16.4	34.6	-3.9	-5.2	-4.0	-4.2	-5.7	-4.1	-4.3	-3.6	-4.2	-4.3	-4.2	-3.8	-3.9	-5.9	-3.0	-4.1	-2.2	-3.8	-3.9	-3.3	-2.4	-4.0	-2.7	-4.5
Time employed in main current job	3.1	3.6	9.4	2.8	1.9	2.0	1.7	2.1	1.9	2.2	1.7	1.8	2.3	2.4	1.4	1.8	1.4	3.1	1.1	1.6	1.8	0.9	2.2	1.7	1.5	1.4	1.1
Medication: Omeprazole	3.1	3.7	6.9	-1.4	-2.4	-2.3	-1.6	-0.6	-2.3	-1.9	-2.5	-1.9	-1.8	-1.8	-1.4	-1.0	-1.2	-1.2	-2.6	-2.0	-2.0	-2.4	-1.7	-2.0	-2.1	-2.4	-2.0
Arm predicted mass (right)	3.1	15.7	36.1	-3.8	-5.2	-3.9	-4.0	-5.8	-3.9	-4.2	-3.4	-4.0	-4.3	-4.0	-3.7	-3.7	-6.0	-2.8	-3.9	-1.9	-3.8	-3.7	-3.2	-2.2	-3.9	-2.4	-4.5
Osteoporosis (self-reported)	3.0	3.7	6.9	1.2	2.1	2.0	1.6	0.6	2.0	2.4	2.2	1.6	2.3	2.2	1.2	1.5	2.6	1.1	2.5	1.6	1.7	2.5	1.9	1.8	2.2	1.6	1.9
Financial situation satisfaction	3.0	3.8	8.0	-2.8	-1.9	-1.8	-2.1	-2.2	-1.8	-2.0	-1.6	-1.6	-2.2	-2.2	-0.9	-1.7	-2.2	-2.8	-1.3	-1.7	-2.1	-1.5	-2.2	-1.7	-1.9	-1.5	-1.7
Impedance of whole body	3.0	15.3	35.5	3.4	5.8	3.8	3.6	6.0	4.1	3.9	3.5	3.6	3.8	3.5	3.8	3.0	5.7	0.7	4.6	1.0	3.6	4.9	2.2	1.1	4.1	1.5	6.0
Hearing difficulty/problems with background noise	2.9	4.6	6.2	1.8	2.3	2.2	2.4	2.4	2.0	2.2	2.1	2.5	2.3	2.0	2.5	2.0	1.5	1.8	2.1	2.0	2.3	2.3	2.2	2.2	2.1	1.4	2.3
Heel bone mineral density (BMD) T-score, automated (right)	2.9	6.7	10.0	-2.7	-3.1	-3.0	-1.8	-1.4	-3.0	-2.8	-3.0	-3.2	-2.4	-2.6	-1.9	-1.9	-1.6	-2.1	-3.1	-2.4	-3.0	-3.0	-2.2	-2.4	-2.7	-2.5	-3.1
Sitting height	2.8	19.6	30.0	-4.0	-3.8	-4.6	-4.7	-3.5	-4.1	-4.8	-4.9	-5.5	-4.6	-4.6	-3.8	-4.2	-4.2	-4.1	-4.9	-5.2	-4.0	-4.6	-5.1	-5.4	-4.3	-3.8	-2.5
Arm fat-free mass (left)	2.8	14.4	31.0	-3.7	-4.9	-3.8	-3.9	-5.3	-3.8	-4.0	-3.4	-3.9	-4.1	-3.9	-3.5	-3.5	-5.6	-2.7	-3.9	-2.1	-3.5	-3.6	-3.1	-2.3	-3.8	-2.6	-4.1
Medication: Amlodipine	2.7	3.8	6.4	2.2	2.2	2.1	2.0	1.3	2.3	1.8	2.1	1.3	1.9	1.8	1.3	1.5	2.5	1.3	1.8	2.1	2.4	1.7	2.1	2.2	2.2	2.2	1.9
Arm fat-free mass (right)	2.7	13.8	34.2	-3.6	-5.0	-3.6	-3.7	-5.4	-3.7	-4.0	-3.2	-3.7	-4.0	-3.8	-3.5	-3.4	-5.8	-2.6	-3.6	-1.6	-3.4	-3.5	-2.9	-1.9	-3.7	-2.3	-4.3
Qualifications: nursing, teaching	2.7	4.2	8.2	1.7	2.2	2.1	2.2	1.6	2.2	2.0	2.3	1.6	2.0	2.1	1.0	1.4	2.6	1.2	2.3	1.9	2.3	2.9	2.0	2.0	2.6	1.5	2.6
Asthma (self-reported)	2.7	5.3	7.7	-2.7	-2.3	-2.6	-2.1	-1.9	-2.6	-2.4	-2.2	-2.6	-2.3	-2.7	-1.8	-2.8	-2.6	-2.8	-1.7	-2.0	-2.4	-1.5	-2.4	-2.0	-2.0	-2.2	-2.0
Irritability	2.7	4.5	9.6	1.7	1.7	2.1	2.3	1.7	1.8	2.1	2.5	2.3	2.0	1.5	2.0	2.1	1.5	1.2	2.8	3.1	2.0	2.7	2.3	2.9	2.3	1.5	1.6
Lung FVC	2.6	13.4	25.0	3.5	3.3	4.0	3.8	2.6	3.6	3.9	3.7	3.7	3.9	3.7	2.4	3.4	2.0	4.1	3.3	4.3	4.1	2.8	4.2	4.5	3.9	5.0	2.4
Heel bone mineral density (BMD) T-score, automated (left)	2.6	5.9	11.0	-2.6	-3.0	-2.9	-1.6	-1.3	-3.0	-2.6	-2.8	-2.5	-2.2	-2.3	-1.8	-2.0	-2.2	-1.8	-2.9	-2.0	-3.0	-3.0	-1.9	-1.9	-2.5	-2.0	-3.3
Mouth/teeth dental problems	2.6	4.0	8.7	-0.8	-1.8	-2.2	-1.2	0.5	-2.2	-1.8	-2.5	-1.5	-1.5	-1.3	-1.1	-1.5	-2.7	-0.2	-2.8	-2.4	-2.1	-2.7	-1.9	-2.5	-2.5	-2.9	-2.0
Heart disease (mother)	2.6	3.1	5.0	-2.0	-2.1	-1.8	-1.4	-1.3	-1.8	-1.8	-2.0	-2.0	-1.6	-1.6	-1.9	-1.3	-1.3	-0.7	-2.2	-2.0	-1.7	-2.2	-1.8	-2.1	-1.9	-1.4	-1.8
Hypertension (Self-reported)	2.6	7.2	10.5	-2.6	-3.0	-3.0	-2.7	-2.2	-3.0	-3.0	-2.8	-2.8	-3.0	-3.0	-1.8	-2.5	-0.9	-2.9	-2.7	-2.3	-2.8	-2.2	-2.7	-2.6	-3.1	-3.2	-2.6
Illnesses of siblings: Diabetes	2.6	3.2	5.7	-1.9	-2.1	-1.7	-1.4	-1.9	-1.6	-1.7	-2.0	-2.3	-1.5	-1.7	-2.0	-1.2	-1.9	-0.2	-2.3	-2.1	-1.6	-2.4	-1.8	-1.9	-1.8	-1.0	-1.5
Crohns Disease (2017)	2.5	5.4	7.5	-2.6	-2.5	-2.6	-2.2	-2.1	-2.6	-2.5	-2.3	-1.4	-2.5	-2.6	-2.2	-2.0	-2.2	-2.6	-2.0	-2.0	-2.6	-2.1	-2.2	-2.1	-2.4	-2.0	-2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.5	3.8	7.6	-1.5	-2.3	-2.4	-2.0	-0.5	-2.5	-2.2	-2.2	-1.9	-2.0	-2.0	-0.7	-1.1	-0.5	-1.8	-2.2	-1.8	-2.6	-2.5	-1.9	-1.7	-1.9	-1.4	-2.8
Vascular/heart problems diagnosed by doctor	2.5	6.9	10.4	2.6	3.2	3.0	2.5	2.2	3.0	2.9	2.6	2.6	2.8	2.9	1.6	2.4	1.1	2.9	2.6	1.9	2.9	2.5	2.4	2.1	3.1	3.1	3.2
High blood pressure	2.4	6.6	9.9	-2.5	-3.1	-2.9	-2.5	-2.2	-2.9	-2.9	-2.5	-2.5	-2.9	-2.9	-1.9	-2.5	-1.3	-3.0	-2.5	-1.8	-2.7	-2.1	-2.4	-2.1	-3.0	-3.0	-2.8
Illnesses of father: High blood pressure	2.4	3.0	5.7	-0.2	-2.0	-1.9	-1.5	-0.0	-1.9	-1.9	-1.8	-1.3	-1.9	-1.3	-0.8	-2.4	-1.0	-1.2	-2.4	-1.4	-2.0	-2.0	-1.7	-1.7	-2.0	-2.4	-2.1
Heel T-Score	2.3	18.4	25.6	-4.1	-4.9	-4.6	-3.5	-3.8	-4.4	-4.7	-4.3	-4.5	-4.5	-4.0	-2.9	-4.9	-3.9	-2.9	-4.8	-4.2	-5.1	-4.9	-4.1	-4.2	-4.0	-4.0	-5.0
Asthma	2.3	4.4	7.1	-2.6	-2.1	-2.4	-2.0	-1.9	-2.5	-2.1	-2.0	-2.4	-2.1	-2.5	-1.6	-2.5	-2.6	-2.7	-1.4	-1.7	-2.2	-1.2	-2.1	-1.7	-1.7	-1.9	-1.8
Bipolar Disorder (2018)	2.2	3.5	6.7	-2.1	-1.2	-1.9	-2.0	-0.6	-1.7	-1.9	-2.0	-2.6	-1.8	-2.2	-1.5	-1.4	0.2	-2.1	-1.7	-2.6	-1.8	-1.3	-2.6	-2.5	-1.6	-2.4	-0.2
Tense / ‘highly strung’	2.2	3.7	8.8	1.7	1.9	1.7	1.7	2.0	1.7	1.9	2.0	1.1	1.8	1.7	2.4	2.1	3.0	1.4	2.1	1.7	1.9	2.4	1.9	1.8	2.3	0.9	1.9
Shortness of breath walking on level ground	2.2	2.6	4.6	-1.4	-1.6	-1.7	-1.7	-0.2	-1.8	-1.9	-1.8	-1.5	-2.0	-2.1	-0.9	-1.8	-0.7	-1.5	-1.8	-1.3	-1.7	-1.9	-1.9	-1.5	-2.1	-1.1	-1.7
Townsend deprivation index at recruitment	2.1	2.9	5.6	-1.5	-2.4	-1.9	-1.8	-2.1	-1.9	-1.9	-1.6	-1.3	-1.8	-1.8	-1.1	-1.9	-1.8	-1.7	-1.8	-0.9	-1.6	-1.7	-1.4	-1.1	-1.8	-1.6	-2.0
Medication: Levothyroxine sodium	2.1	3.5	8.1	2.1	2.1	2.0	1.7	2.8	1.9	1.9	2.0	1.8	1.9	2.1	2.5	1.3	1.7	1.7	1.7	1.6	1.8	1.4	1.8	1.7	1.6	1.8	1.4
Cholesterol lowering medication	2.1	3.1	6.7	-1.6	-1.6	-1.7	-1.8	-0.8	-1.7	-2.0	-1.9	-1.8	-1.9	-2.1	-1.2	-1.2	-0.5	-1.5	-1.9	-1.6	-1.8	-2.2	-2.1	-2.0	-2.6	-1.7	-1.8
Neuroticism (Nagel 2018)	2.0	4.7	14.5	2.0	1.9	2.0	2.1	3.0	1.6	2.0	2.3	2.5	1.7	1.6	3.8	1.9	2.0	1.0	2.5	3.0	1.7	2.2	2.5	2.8	1.9	1.1	0.6
Bipolar Disorder (2011)	2.0	1.9	4.2	-1.8	-1.1	-1.5	-1.5	-0.5	-1.3	-1.5	-1.4	-2.0	-1.5	-1.5	-1.4	-0.6	0.1	-2.1	-1.1	-1.7	-1.5	-1.2	-1.6	-1.5	-1.0	-1.0	-0.8
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	3.6	-1.8	-1.8	-1.6	-1.4	-1.5	-1.4	-1.6	-1.6	-1.9	-1.5	-1.5	-1.3	-1.7	-1.8	-1.0	-1.6	-1.0	-1.4	-1.7	-1.2	-1.1	-1.7	-0.8	-1.4
Emphysema/chronic bronchitis	2.0	2.3	4.0	-1.7	-1.9	-1.6	-1.9	-2.0	-1.6	-1.5	-1.5	-1.4	-1.7	-1.5	-0.8	-1.1	-1.2	-0.8	-1.4	-1.5	-1.5	-1.4	-1.5	-1.6	-1.4	-1.4	-1.6
Taking other prescription medications	1.9	2.9	5.4	-1.4	-2.0	-2.1	-1.9	-0.9	-2.2	-1.6	-1.9	-2.2	-1.6	-1.9	-0.3	-1.4	-0.7	-1.8	-1.8	-1.6	-1.9	-1.4	-1.7	-1.7	-1.8	-2.3	-1.8
Hair/balding pattern: Pattern 2	1.9	2.5	4.2	-1.3	-1.9	-1.7	-1.8	-1.5	-1.7	-1.7	-1.5	-1.5	-1.8	-1.4	-1.7	-1.9	-0.4	-2.0	-1.6	-1.2	-1.7	-1.1	-1.4	-1.3	-1.4	-1.8	-1.6
Father’s age at death	1.9	2.5	4.8	0.7	2.0	1.9	1.2	0.5	2.0	1.8	1.8	1.0	1.9	1.9	1.2	1.1	1.0	1.7	1.8	1.1	1.8	1.4	1.6	1.2	2.1	2.2	1.9
Age at First Birth	1.8	2.6	8.1	1.4	1.6	1.6	1.4	1.1	1.3	1.8	0.9	2.3	1.6	1.9	0.4	2.7	1.4	1.9	1.1	0.7	1.5	0.9	1.6	1.2	1.8	2.8	1.2
Blood Red Count	1.8	17.1	40.3	-4.1	-4.8	-4.5	-3.6	-3.8	-4.4	-4.2	-4.6	-3.6	-3.9	-4.3	-4.4	-4.4	-6.3	-2.8	-4.8	-3.3	-3.6	-4.5	-3.8	-3.3	-4.5	-2.5	-3.6
Worrier / anxious feelings	1.8	3.3	8.1	1.7	1.7	1.8	1.6	1.9	1.4	2.0	2.0	1.8	1.9	1.8	2.8	1.4	1.7	1.6	2.1	2.4	1.4	1.6	2.2	2.4	1.7	1.1	0.3
Noisy workplace	1.8	2.3	7.0	-0.9	-1.4	-1.6	-0.9	-0.2	-1.6	-1.8	-1.6	-1.2	-1.8	-1.5	-0.7	-0.8	-1.2	-1.1	-1.7	-1.0	-1.9	-2.1	-1.4	-1.1	-2.3	-1.5	-2.6
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.1	11.8	-1.3	-1.8	-1.1	-1.7	-3.4	-1.0	-1.1	-1.0	-1.3	-0.9	-1.4	-2.8	-1.4	-1.5	-0.7	-1.5	-0.8	-0.8	-1.5	-0.8	-0.7	-1.1	-0.2	-1.2
Eye problems/disorders: Glaucoma	1.8	2.1	4.0	-1.1	-1.7	-1.8	-1.0	-0.4	-2.0	-1.5	-1.6	-1.7	-1.4	-1.5	-0.7	-0.9	-1.9	-1.3	-1.4	-1.2	-1.8	-1.1	-1.4	-1.2	-1.3	-1.8	-1.6
Number of operations (self-reported)	1.8	2.7	11.0	-1.5	-2.8	-1.8	-0.9	-0.7	-2.0	-1.4	-1.4	-1.7	-1.3	-1.7	-0.1	-0.8	-3.3	-1.1	-1.4	-0.3	-1.6	-1.6	-0.8	-0.4	-1.7	-2.3	-2.6
Waist Hip Ratio (WHR)	1.7	7.8	16.7	-3.0	-2.3	-3.1	-3.1	-1.7	-2.9	-2.9	-3.0	-3.2	-2.9	-3.2	-1.5	-2.0	-0.6	-4.1	-2.5	-3.5	-3.2	-2.4	-3.4	-3.5	-2.6	-2.2	-1.9
Medication for pain relief, constipation, heartburn	1.7	2.8	6.0	0.8	2.5	2.0	1.3	0.9	2.1	1.6	1.9	1.6	1.3	1.5	0.9	1.9	1.8	0.8	2.4	1.1	1.8	2.3	1.1	1.1	1.9	1.6	2.4
Medication: Blood pressure	1.7	3.0	4.5	-1.8	-2.1	-2.1	-1.4	-1.4	-2.0	-1.9	-1.9	-2.0	-1.9	-1.7	-1.6	-1.5	-0.3	-1.1	-1.9	-1.6	-1.7	-1.5	-1.5	-1.7	-1.9	-1.9	-1.8
Mean time to correctly identify matches	1.7	3.2	5.8	1.6	2.3	2.1	1.7	1.1	2.1	1.9	1.6	1.1	1.8	2.1	1.6	2.0	2.1	2.4	1.5	1.3	2.1	1.4	1.6	1.3	1.6	1.9	2.2
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.5	9.8	-1.7	-2.0	-2.0	-1.9	-1.7	-1.8	-2.0	-1.8	-1.9	-1.9	-1.9	-1.3	-2.1	-3.1	-2.3	-1.8	-2.0	-1.9	-1.5	-2.0	-1.7	-1.2	-1.3	-1.0
Hearing aid user	1.7	1.9	3.2	1.6	0.7	1.2	1.6	1.0	1.0	1.3	1.5	1.2	1.3	1.6	1.2	1.6	1.0	1.7	1.2	1.6	1.1	1.6	1.8	1.7	1.7	1.5	0.3
Reaction Time	1.6	3.0	4.9	1.6	2.2	2.0	1.8	1.3	1.9	1.8	1.6	1.6	1.6	2.0	2.1	1.7	1.7	2.2	1.6	1.3	1.8	1.2	1.5	1.3	1.6	1.8	1.8
Breast Cancer	1.6	3.9	6.7	2.1	1.7	2.2	2.0	1.4	2.0	2.1	2.1	2.6	2.1	2.0	2.0	1.9	0.4	2.2	2.1	2.3	1.8	1.7	2.2	2.5	1.8	2.0	1.4
Supplements: Zinc	1.6	1.7	3.2	0.8	1.6	1.5	1.5	1.8	1.5	1.5	1.1	1.0	1.6	1.4	0.9	1.2	0.8	1.4	1.3	0.8	1.5	0.9	1.3	0.9	1.3	1.5	1.6
Falls in the last year	1.6	2.1	5.5	-1.3	-0.7	-1.2	-2.1	-1.3	-0.9	-1.3	-1.4	-2.0	-1.3	-1.5	-0.9	-1.4	0.4	-1.7	-1.1	-1.9	-0.8	-0.5	-2.0	-2.2	-1.4	-2.3	0.6
Breastfed as a baby	1.6	2.0	4.8	1.1	1.7	1.8	1.5	0.5	1.9	1.4	1.6	0.9	1.5	1.2	0.7	0.9	-0.2	1.6	1.6	1.5	1.7	1.0	1.3	1.5	1.5	2.2	1.6
Medication: Aspirin	1.6	2.1	4.5	-1.3	-1.1	-1.4	-1.1	0.0	-1.3	-1.4	-1.6	-1.6	-1.3	-1.2	-1.1	-1.6	0.0	-0.9	-1.6	-1.8	-1.4	-1.7	-1.4	-1.9	-1.9	-2.1	-1.5
Lupus	1.5	2.2	5.2	-1.0	-1.0	-1.3	-2.0	-1.2	-1.2	-1.6	-1.3	-1.2	-1.8	-1.3	-0.2	-2.1	-1.3	-2.1	-1.2	-1.6	-1.3	-0.6	-2.1	-2.0	-1.3	-2.3	0.1
Mouth/teeth dental problems: Bleeding gums	1.5	2.0	6.0	-1.6	-2.2	-1.2	-1.6	-2.5	-1.4	-1.3	-0.8	-1.4	-1.3	-1.3	-2.2	-0.5	-1.5	-1.6	-0.8	0.4	-1.1	-1.0	-0.5	0.2	-1.1	0.7	-2.3
Glaucoma (self-reported)	1.5	1.8	4.3	-1.1	-1.6	-1.8	-1.1	-0.6	-1.9	-1.2	-1.6	-1.6	-1.1	-1.1	-1.0	-0.3	-1.0	-1.1	-1.5	-1.5	-1.6	-0.9	-1.2	-1.4	-1.2	-2.1	-1.1
Worry too long after embarrassment	1.5	2.6	4.6	1.0	1.5	1.6	1.6	1.3	1.4	1.6	1.9	1.9	1.5	1.4	2.1	1.2	1.0	0.8	2.0	2.1	1.5	1.6	2.0	2.2	1.6	2.1	0.6
Comparative height size at age 10	1.5	8.1	11.7	-2.7	-2.4	-3.0	-2.7	-1.8	-2.8	-3.0	-3.0	-3.2	-2.9	-3.1	-2.2	-2.7	-3.1	-3.3	-2.8	-3.4	-3.1	-3.0	-3.2	-3.3	-2.6	-2.3	-2.2
Average weekly red wine intake	1.5	2.2	6.0	1.1	2.1	1.6	1.4	1.3	1.8	1.3	1.5	1.0	1.1	1.2	0.6	1.6	2.5	0.4	2.0	0.9	1.5	1.9	1.1	0.9	1.7	1.2	2.0
Eye problems/disorders: Cataract	1.5	1.7	3.5	1.1	1.2	1.3	1.1	1.1	1.3	1.6	1.2	1.0	1.5	1.3	-0.2	1.9	1.1	1.1	1.4	0.8	1.6	1.7	1.1	1.0	1.6	1.5	1.9
Medication: Paracetamol	1.5	2.4	5.7	-0.7	-2.4	-1.7	-1.8	-1.5	-1.8	-1.5	-1.4	-1.9	-1.3	-1.3	-1.0	-1.6	-2.0	-1.1	-2.0	-0.8	-1.5	-1.8	-0.9	-0.7	-1.4	-1.0	-2.2
Supplements: Calcium	1.5	1.7	3.3	0.6	1.2	1.2	0.9	0.3	1.2	1.8	1.3	0.5	1.8	1.7	1.2	1.2	1.2	1.5	1.5	1.0	1.4	1.6	1.4	1.0	1.6	0.7	1.6
Blood Platelet Count	1.4	15.9	44.4	-4.3	-3.8	-3.9	-5.0	-3.0	-3.6	-3.8	-4.0	-6.7	-3.6	-4.2	-3.9	-4.2	-2.4	-4.9	-3.4	-4.1	-3.3	-2.8	-4.2	-4.3	-3.8	-3.8	-1.9
Chronic bronchitis/emphysema (father)	1.4	1.6	4.8	-1.2	-2.2	-1.5	-1.0	-1.3	-1.6	-1.2	-1.1	-1.5	-1.1	-1.3	-1.3	-1.2	-1.5	-0.9	-1.0	-0.6	-1.4	-1.2	-0.9	-0.4	-0.5	0.2	-2.0
Ever highly irritable/argumentative for 2 days	1.4	1.7	7.2	1.0	1.3	1.2	1.2	2.7	0.8	1.4	0.7	2.3	1.1	1.5	2.0	2.2	1.1	0.9	0.7	0.8	1.0	0.7	1.1	0.8	0.4	0.7	0.6
Age at first live birth	1.4	2.4	3.6	1.2	1.9	1.8	1.8	1.6	1.9	1.7	1.8	1.7	1.6	1.6	0.6	1.8	1.2	1.3	1.7	1.5	1.8	1.6	1.5	1.3	1.2	1.0	1.6
Health satisfaction	1.4	1.8	3.2	-0.6	-1.6	-1.4	-1.1	0.2	-1.5	-1.6	-1.6	-1.8	-1.5	-1.5	-0.4	-1.3	-1.0	-0.7	-1.7	-1.1	-1.5	-1.7	-1.5	-1.1	-1.4	-1.4	-1.4
Ever had bowel cancer screening	1.4	1.6	2.7	1.0	1.6	1.5	1.4	1.0	1.5	1.6	1.2	1.1	1.5	1.2	0.2	1.5	1.0	1.6	1.4	1.0	1.4	1.1	1.5	1.0	1.0	0.9	1.3
Average weekly beer plus cider intake	1.4	2.1	5.5	-1.0	-2.4	-1.4	-1.5	-1.6	-1.4	-1.6	-1.3	-1.4	-1.7	-1.6	-1.9	-1.3	-2.2	-1.0	-1.6	-0.9	-1.2	-1.4	-1.3	-0.7	-1.1	-0.0	-1.5
Qualifications: A levels/AS levels or equivalent	1.3	2.8	4.5	1.8	1.9	1.7	1.7	1.6	1.8	1.8	1.4	1.9	1.9	1.9	0.6	1.9	2.1	1.6	1.1	1.3	1.9	1.3	1.7	1.3	1.7	1.9	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.1	7.1	2.2	2.3	2.5	1.9	1.0	2.7	2.0	2.3	1.5	2.1	2.2	1.3	1.6	1.6	2.1	1.8	1.8	2.5	1.5	2.0	1.9	2.3	2.4	2.3
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	5.2	1.3	1.0	1.3	1.1	1.4	1.2	1.5	0.8	0.8	1.6	1.2	0.3	2.3	1.7	2.2	0.4	0.7	1.4	0.2	1.3	0.8	0.7	0.7	0.9
Nervous feelings	1.2	2.2	6.1	0.9	1.8	1.6	0.9	1.1	1.5	1.6	1.6	1.2	1.5	1.4	2.2	0.6	2.5	1.0	1.8	1.4	1.5	1.5	1.4	1.2	1.5	0.8	1.4
Forced expiratory volume in 1-second (FEV1)	1.2	4.1	7.8	2.0	2.1	2.5	2.1	1.1	2.5	1.9	2.3	1.5	2.0	1.9	1.4	1.9	1.3	1.4	2.0	2.3	2.4	1.6	2.0	2.4	2.4	2.8	1.9
Standing height	1.2	12.1	20.4	-3.7	-2.9	-3.5	-3.6	-3.0	-3.0	-3.7	-3.4	-4.2	-3.6	-3.9	-3.2	-3.4	-4.5	-4.5	-2.9	-3.9	-3.1	-2.5	-4.0	-4.0	-3.0	-3.2	-1.3
Migraine (self-reported)	1.2	1.5	6.4	-1.3	-1.4	-1.1	-1.0	-1.5	-1.1	-1.0	-1.1	-1.5	-0.9	-0.9	-0.7	-0.9	-2.5	-0.3	-1.1	-0.9	-1.3	-1.6	-0.7	-0.9	-1.1	-0.6	-1.9
Supplements: Vitamin C	1.2	1.4	3.0	0.5	1.4	1.3	1.1	1.2	1.3	1.5	1.0	0.9	1.7	1.1	0.5	1.2	0.7	1.3	1.2	0.9	1.5	0.7	1.3	1.1	1.4	1.7	1.2
Medication: Gliclazide	1.2	1.4	3.5	-1.1	-1.7	-1.2	-1.1	-1.8	-1.1	-1.1	-1.1	-1.6	-0.8	-1.0	-1.9	-1.2	-1.2	-0.8	-1.3	-0.8	-0.9	-1.0	-0.6	-0.8	-1.1	-0.8	-1.3
Medication: Lisinopril	1.2	1.5	2.7	-1.1	-1.5	-1.5	-0.9	-1.0	-1.4	-1.3	-1.3	-1.6	-1.1	-1.4	-1.4	-0.9	-1.2	-1.0	-1.3	-1.3	-1.2	-1.0	-1.2	-1.2	-1.1	-1.1	-1.0
Worry (Nagel 2018)	1.1	2.3	7.8	1.4	1.8	1.4	1.1	2.2	1.2	1.4	1.6	1.3	1.2	1.3	2.6	0.9	2.8	0.5	1.8	1.3	1.1	1.9	1.3	1.2	1.5	0.1	1.1
Neuroticism (2016)	1.1	1.5	7.1	1.5	0.7	0.8	0.9	1.7	0.5	0.9	1.1	1.4	0.8	0.9	2.7	0.7	1.8	0.7	1.1	1.7	0.7	1.0	1.1	1.7	1.0	1.1	0.1
Frequency of depressed mood in last 2 weeks	1.1	1.5	3.2	-0.8	-1.2	-1.4	-1.4	-0.5	-1.4	-1.4	-1.5	-1.2	-1.3	-1.7	-0.1	-1.3	-0.6	-1.0	-1.6	-1.0	-1.2	-1.8	-1.4	-1.1	-1.4	-0.6	-1.1
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.5	-1.3	-1.6	-1.4	-0.8	-0.7	-1.4	-1.0	-1.6	-1.1	-0.6	-1.1	-1.8	-0.8	-1.9	-0.2	-1.5	-0.9	-1.0	-1.3	-0.8	-0.7	-0.7	0.0	-1.0
Number of incorrect matches in round	1.1	1.8	4.6	0.9	2.1	1.4	1.4	1.5	1.4	1.6	0.9	1.2	1.3	1.5	1.3	1.4	0.5	1.7	1.2	0.1	1.5	1.2	0.8	0.1	1.4	1.2	2.1
Neuroticism score	1.1	2.2	8.5	1.0	1.0	1.2	1.2	1.6	0.8	1.3	1.6	2.2	1.1	0.8	2.9	1.0	1.1	0.3	1.8	2.5	1.0	1.6	1.7	2.3	1.2	1.1	0.2
Pulse wave Arterial Stiffness index	1.1	1.2	3.8	-0.9	-0.5	-1.2	-1.1	-0.4	-1.0	-0.9	-1.6	-1.3	-0.8	-0.9	-0.2	-0.6	-0.5	-0.5	-1.4	-2.0	-1.0	-1.5	-1.3	-1.9	-1.1	-1.1	-0.6
Medication: Paracetamol	1.1	1.8	5.6	-0.1	-2.4	-1.4	-1.3	-0.9	-1.6	-1.2	-1.2	-1.4	-1.0	-1.1	-0.5	-1.5	-2.3	-0.6	-1.9	-0.0	-1.3	-1.8	-0.5	-0.1	-1.3	-0.7	-2.3
Chronic bronchitis/emphysema (mother)	1.1	1.3	5.8	-0.6	-1.1	-1.2	-0.9	0.2	-1.3	-0.9	-1.2	-0.8	-1.0	-0.9	-0.7	-0.7	-1.2	-0.5	-1.3	-1.2	-1.2	-1.1	-1.1	-1.3	-1.7	-2.4	-1.1
Medication: Aspirin	1.1	1.4	3.9	-1.1	-0.8	-1.2	-1.0	0.1	-1.1	-1.1	-1.3	-1.4	-1.0	-0.9	-0.8	-1.4	0.4	-0.8	-1.2	-1.5	-1.2	-1.2	-1.2	-1.6	-1.6	-2.0	-1.2
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	5.0	1.4	1.4	1.5	0.6	0.3	1.5	1.3	1.5	0.7	1.4	1.3	1.6	0.6	2.2	0.5	1.4	1.3	1.4	1.2	1.4	1.5	1.5	1.5	1.3
Schizophrenia (2014)	1.0	2.2	7.0	1.4	1.4	1.1	1.8	2.7	1.0	1.2	1.4	1.1	1.1	1.0	1.7	1.0	2.0	1.1	1.7	0.9	1.1	2.1	0.7	1.1	1.9	0.9	1.9
Blood Eosinophil Count	1.0	7.5	18.7	-3.2	-3.0	-2.7	-1.7	-2.0	-2.6	-2.9	-2.4	-2.5	-2.9	-3.0	-3.2	-2.7	-4.3	-3.1	-2.3	-1.9	-2.6	-2.1	-2.7	-2.2	-2.9	-3.0	-2.4
Chronotype (morning person)	1.0	2.2	4.4	1.5	1.5	1.4	1.7	1.7	1.2	1.6	1.7	1.3	1.7	1.6	1.5	1.5	0.7	1.3	1.7	2.1	1.1	1.3	1.8	1.9	1.4	0.8	0.5
Hayfever, allergic rhinitis or eczema	1.0	2.2	6.6	-1.6	-1.3	-1.4	-1.8	-2.6	-1.4	-1.2	-1.5	-1.2	-1.0	-1.0	-2.1	-1.0	-2.1	-0.3	-1.7	-1.6	-1.6	-1.8	-1.2	-1.4	-1.1	-0.5	-1.4
Had other major operations	1.0	1.3	3.2	-1.0	-1.0	-1.1	-1.0	-0.2	-1.2	-1.0	-1.3	-0.7	-0.9	-1.1	0.6	-0.6	-1.3	-0.8	-1.2	-0.8	-1.1	-1.7	-0.8	-0.9	-1.6	-1.8	-1.6
Length of working week for main job	1.0	1.2	2.8	-1.1	-1.1	-0.8	-1.4	-1.0	-0.9	-1.1	-0.7	-0.2	-1.5	-1.2	-0.1	-1.2	-1.2	-1.7	-0.5	-0.4	-1.1	-0.8	-1.0	-0.6	-1.2	-1.4	-1.6
Osteoarthritis (self-reported)	1.0	1.3	6.6	-1.4	-1.2	-0.9	-1.1	-1.2	-1.1	-1.1	-0.9	-0.3	-1.3	-1.3	-0.5	-1.1	-2.6	-0.7	-0.9	-0.5	-0.9	-1.2	-0.8	-0.5	-1.1	0.1	-1.8
Basal cell carcinoma (self-reported)	1.0	1.2	3.6	0.4	0.6	0.9	0.8	-0.0	0.8	1.2	1.2	1.3	1.1	1.0	0.6	0.7	1.2	0.3	1.4	1.6	1.3	1.9	1.5	1.6	0.8	0.5	1.0
Body Mass Index (BMI) (2010)	0.9	1.3	3.7	-1.4	-1.8	-1.1	-1.2	-1.9	-1.2	-1.2	-0.9	-0.9	-1.2	-1.3	-1.4	-0.8	-1.2	-0.6	-0.9	-0.1	-1.0	-0.6	-0.9	-0.4	-1.0	-0.9	-1.1
Coronary Artery Disease (CAD)	0.9	1.1	3.3	-1.2	-0.7	-1.1	-1.1	-0.6	-0.9	-1.0	-1.3	-1.1	-0.8	-1.0	-0.4	-0.6	-0.6	-0.3	-1.3	-1.8	-0.9	-1.1	-1.3	-1.8	-0.9	-1.2	0.3
Ever used hormone-replacement therapy (HRT)	0.9	1.1	3.8	1.1	1.3	1.3	0.6	0.9	1.1	1.4	0.8	1.1	1.2	1.5	0.4	1.5	1.3	2.0	0.8	0.0	0.8	0.6	0.8	0.2	0.9	0.7	0.8
Hand grip strength (right)	0.9	2.5	12.9	-1.3	-1.9	-1.6	-0.8	-1.3	-1.6	-1.7	-1.3	-1.0	-1.7	-1.4	-1.4	-2.1	-3.6	-1.5	-1.3	-0.6	-1.6	-1.4	-1.2	-0.6	-1.4	-0.3	-2.1
Fed-up feelings	0.9	1.7	5.7	1.4	0.5	0.8	1.6	2.3	0.4	0.7	0.8	1.8	0.6	0.3	2.4	1.1	0.8	0.4	0.9	2.0	0.6	0.4	1.1	2.1	1.0	2.0	-0.2
Medication: Atenolol	0.9	1.1	3.8	-1.1	-1.2	-1.2	-1.0	-0.5	-1.1	-0.9	-1.2	-1.6	-0.9	-0.7	0.0	-1.0	-0.1	-0.3	-1.2	-1.3	-1.0	-0.8	-1.0	-1.3	-0.9	-2.0	-0.8
Medication: Simvastatin	0.9	1.3	4.5	-1.4	-0.4	-1.0	-0.7	0.1	-0.9	-0.9	-1.4	-2.1	-0.8	-1.3	0.2	-0.7	0.9	-0.1	-1.1	-1.5	-1.0	-1.7	-1.4	-1.6	-1.6	-1.2	-0.5
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	4.8	1.7	1.5	1.4	1.1	2.2	1.3	1.3	1.7	0.9	1.2	1.2	1.6	1.1	1.5	0.9	1.4	1.3	1.2	1.5	1.1	1.3	1.2	1.0	1.1
Number of full sisters	0.9	1.1	3.4	-0.9	-1.6	-1.1	-1.1	-1.0	-1.3	-1.2	-1.0	-0.8	-1.2	-1.1	-0.0	-1.2	-0.8	-0.3	-1.2	0.4	-0.8	-0.9	-0.7	-0.1	-1.8	-1.0	-1.3
Breast cancer (self-reported)	0.9	1.0	3.3	-0.8	-0.5	-0.6	-1.5	-0.7	-0.6	-1.1	-0.9	-0.8	-1.3	-1.1	-0.6	-0.8	-1.0	-0.5	-1.0	-0.9	-0.9	-1.2	-1.2	-1.2	-1.8	-1.3	-0.6
Irritable Bowel Disease (IBD)	0.8	1.9	5.1	-1.4	-1.5	-1.5	-1.1	-0.6	-1.6	-1.4	-1.3	-0.1	-1.5	-1.3	-1.2	-0.8	-2.3	-1.1	-1.2	-1.0	-1.7	-1.3	-1.3	-1.3	-1.6	-1.4	-2.0
Height	0.8	15.2	23.0	-3.7	-3.4	-4.1	-4.0	-2.7	-3.7	-4.0	-4.4	-4.6	-3.9	-4.3	-3.6	-3.5	-4.8	-4.4	-3.8	-4.3	-3.6	-3.5	-4.4	-4.4	-3.8	-3.5	-2.1
Smoking Status	0.8	1.9	5.8	-0.9	-1.3	-1.2	-0.9	-0.2	-1.3	-1.5	-0.8	-1.1	-1.6	-1.8	0.9	-1.8	-1.5	-2.4	-0.7	-0.6	-1.8	-1.0	-1.6	-0.8	-1.6	-1.6	-1.6
Neuroticism	0.8	2.0	10.4	1.5	1.0	1.0	1.0	1.8	0.5	1.2	1.2	1.7	0.8	0.9	3.2	1.2	1.8	0.5	1.4	2.0	0.6	1.2	1.5	2.0	1.0	0.9	-0.2
Tanning	0.8	9.7	13.5	3.2	3.5	3.2	3.3	3.4	3.3	3.5	3.0	2.6	3.7	3.5	2.9	3.4	2.4	2.9	2.9	2.0	3.3	2.9	3.0	2.4	3.6	2.8	3.4
Serious illness, injury or assault to yourself	0.8	1.0	4.1	-1.0	-1.2	-0.9	-0.9	-1.4	-0.9	-0.6	-1.1	-0.7	-0.6	-0.4	-1.5	-0.2	-0.4	-0.8	-1.3	-1.0	-0.6	-0.8	-0.6	-1.2	-1.3	-2.0	-0.6
Pain all over the body in last month	0.8	0.9	1.6	0.6	1.0	0.9	1.0	0.9	1.0	1.0	0.9	0.3	1.1	0.8	0.7	1.0	1.2	0.6	1.0	0.8	1.2	0.9	0.9	0.7	0.9	1.0	1.1
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.7	0.5	1.3	1.1	1.1	0.7	1.1	1.0	0.9	0.2	0.9	0.6	0.4	0.9	1.0	-0.2	1.2	0.7	1.1	1.1	0.7	0.9	1.0	1.6	1.3
Leg pain on walking	0.8	1.0	4.2	-0.9	-1.3	-0.8	-0.8	-0.7	-0.9	-0.9	-0.6	-1.2	-1.1	-0.9	-0.6	-1.2	-2.1	-0.8	-0.6	-0.2	-1.1	-0.8	-0.9	-0.5	-1.1	-0.9	-1.3
Mineral and other dietary supplements	0.8	1.0	4.3	1.4	1.1	0.8	0.5	1.0	0.6	0.8	0.9	1.8	0.6	0.9	1.0	1.3	2.1	0.4	1.0	0.6	0.4	1.1	0.5	0.8	1.1	0.7	0.7
Fractured/broken bones in last 5 years	0.8	1.0	3.7	0.5	1.0	1.0	0.7	-0.2	1.2	0.9	1.3	0.5	0.9	0.7	0.6	1.1	0.9	-0.4	1.4	0.8	1.2	1.7	0.7	0.6	0.9	-0.4	1.9
Blood White Count	0.7	4.9	9.7	-1.4	-2.8	-2.5	-2.4	-0.9	-2.4	-2.3	-2.2	-3.1	-2.2	-2.4	-1.4	-3.1	-0.4	-2.4	-2.3	-1.7	-2.0	-1.9	-1.9	-1.8	-2.5	-2.6	-1.9
Allergy or Eczema	0.7	1.9	4.5	-1.2	-1.1	-1.4	-1.6	-1.7	-1.5	-1.2	-1.4	-1.0	-1.1	-1.1	-1.2	-1.3	-2.1	-1.1	-1.4	-1.5	-1.7	-1.5	-1.3	-1.3	-1.0	-0.6	-1.4
Hair Pigment	0.7	18.9	25.5	-4.1	-4.8	-4.5	-5.0	-5.0	-4.4	-4.8	-4.1	-4.8	-5.0	-4.7	-4.1	-4.6	-1.1	-4.9	-4.0	-3.3	-4.5	-3.4	-4.5	-3.8	-4.8	-4.2	-4.1
Angina	0.7	0.9	3.8	-1.3	-0.8	-0.8	-0.7	-1.0	-0.7	-0.6	-1.0	-1.3	-0.3	-0.7	-0.6	-0.6	-1.0	0.8	-1.1	-1.4	-0.8	-2.0	-0.7	-1.1	-0.9	-0.6	-1.0
Pack years adult smoking proportion	0.7	1.0	2.1	-0.5	-1.3	-1.0	-1.3	-1.0	-1.0	-1.2	-0.9	-0.1	-1.4	-0.8	0.1	-1.1	-0.2	-0.7	-1.0	-0.7	-1.1	-1.1	-0.9	-0.9	-1.2	-1.2	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	3.3	-0.4	-0.6	-0.7	-1.2	0.1	-0.9	-1.0	-0.7	-0.4	-1.2	-1.4	1.3	-1.1	0.0	-1.8	-0.5	-0.3	-0.8	-0.4	-1.2	-0.6	-1.1	-1.5	-0.6
Happiness	0.7	0.8	3.5	1.3	0.6	0.9	0.4	1.4	0.6	0.8	0.6	1.0	0.7	0.6	1.0	1.4	0.9	0.9	0.4	0.8	0.6	0.2	0.6	1.1	0.8	1.9	0.2
Lung cancer (father)	0.7	0.8	1.8	-0.9	-1.1	-0.7	-1.2	-1.3	-0.8	-1.1	-0.7	-0.8	-1.3	-1.2	-0.0	-1.2	-0.9	-0.7	-0.6	-0.2	-0.7	-0.8	-0.9	-0.4	-0.8	0.0	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.4	0.6	1.1	0.8	1.0	1.1	0.9	0.8	0.5	0.7	1.0	0.9	-0.4	0.8	1.5	0.7	0.6	0.3	0.8	-0.0	1.0	0.7	0.8	1.8	0.3
Pulse wave peak to peak time	0.7	0.8	2.7	0.7	0.3	0.9	0.8	0.2	0.8	0.6	1.3	0.9	0.6	0.6	-0.0	0.4	0.2	0.2	1.2	1.6	0.8	1.4	1.0	1.6	0.9	0.8	0.6
Angina (self-reported)	0.7	0.9	4.2	-1.4	-0.8	-0.8	-0.7	-1.1	-0.6	-0.5	-1.1	-1.3	-0.2	-0.7	-0.7	-0.5	-0.8	0.8	-1.1	-1.4	-0.7	-2.0	-0.7	-1.2	-0.9	-0.6	-0.9
Guilty feelings	0.7	1.1	3.3	0.4	0.5	0.8	1.3	1.1	0.6	1.1	0.9	1.3	1.1	0.7	1.5	1.0	-0.2	1.1	0.9	1.8	1.0	0.7	1.6	1.7	0.8	1.1	-0.1
Alcohol drinker status: Previous	0.7	0.8	3.3	-0.6	-1.2	-1.0	-0.0	0.8	-1.2	-0.8	-1.0	-0.6	-0.7	-0.8	-0.9	0.1	-0.4	0.2	-1.0	-0.4	-1.0	-1.2	-0.5	-0.4	-1.2	-0.6	-1.8
Bipolar Disorder or Schizophrenia	0.6	1.6	3.9	-1.2	-0.9	-1.3	-1.0	0.5	-1.3	-1.4	-1.1	-1.6	-1.4	-1.8	-0.6	-1.4	0.7	-1.8	-0.6	-1.6	-1.3	-0.0	-2.0	-1.5	-0.4	-1.6	0.3
Depression (Nagel 2018)	0.6	0.9	2.5	-0.4	-0.7	-0.9	-1.1	0.2	-1.0	-1.1	-0.8	-0.6	-1.2	-1.4	1.1	-1.0	-0.1	-1.6	-0.6	-0.3	-0.9	-0.7	-1.1	-0.7	-1.3	-1.5	-0.8
Average weekly spirits intake	0.6	0.7	4.8	0.3	1.5	0.7	0.5	1.4	0.8	0.6	0.4	0.5	0.3	0.5	0.8	0.8	2.2	-0.3	0.8	-0.7	0.4	0.6	-0.0	-0.4	0.4	0.5	1.1
Medication for hormone replacement therapy	0.6	0.6	2.6	0.1	-0.9	-0.7	-0.5	-0.0	-0.9	-0.7	-0.7	0.2	-0.9	-0.5	-0.4	-0.6	-1.2	0.1	-1.0	-0.6	-1.1	-1.2	-0.6	-0.4	-1.0	-0.7	-1.6
Medication: Co-codamol	0.6	0.8	3.3	-0.6	-0.8	-0.9	-1.1	-0.7	-0.9	-0.7	-0.9	-0.4	-0.7	-0.4	-0.4	-1.1	0.6	0.3	-1.1	-0.8	-0.7	-0.7	-0.8	-1.3	-1.1	-1.8	-0.5
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	3.6	1.1	1.1	1.3	0.5	0.1	1.2	0.9	1.1	1.4	0.9	0.8	0.1	0.7	-0.7	0.4	1.0	1.1	1.1	0.7	0.9	1.2	1.1	1.9	0.8
Number of children fathered	0.6	0.7	3.7	-0.4	0.3	-0.7	-0.4	0.5	-0.4	-0.5	-1.0	-1.7	-0.3	-0.4	-0.2	-0.2	0.3	-0.6	-0.8	-1.9	-0.5	-0.9	-1.1	-1.6	-0.1	-0.5	0.6
Alzheimer’s Disease (in mother)	0.5	0.6	2.3	1.1	-0.8	-0.2	0.3	0.4	-0.5	0.1	-0.4	0.9	0.3	0.4	-0.3	0.7	-0.4	1.4	-1.0	0.7	0.0	-0.9	0.7	0.9	0.0	1.5	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	3.3	-0.4	-0.6	-0.1	-0.9	-1.8	-0.1	-0.4	-0.3	-0.6	-0.5	-0.3	-0.9	0.0	-1.3	0.1	-0.7	0.5	0.0	-1.1	-0.1	0.1	-1.4	-0.3	-0.6
Leg fat percentage (right)	0.5	1.9	6.4	-0.8	-2.3	-1.2	-1.5	-2.5	-1.4	-1.3	-0.9	-1.1	-1.5	-1.1	-1.3	-1.4	-1.4	-1.0	-1.3	-0.0	-1.3	-1.0	-0.6	-0.3	-1.6	-1.3	-2.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	4.5	0.3	-0.3	-0.4	-0.8	0.6	-0.5	-0.5	-0.6	-0.7	-0.4	-0.5	0.3	0.2	2.1	0.0	-1.0	-0.2	-0.5	-1.7	-0.3	-0.1	-0.6	1.0	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	3.0	-0.0	0.6	0.6	0.3	0.4	0.4	0.4	0.9	-0.6	0.5	0.1	1.7	0.1	-0.4	-0.4	1.5	1.1	0.2	0.8	0.4	1.1	0.9	1.1	-0.1
Had major operations	0.5	0.6	2.9	0.4	-0.6	0.3	0.6	0.1	0.2	0.5	0.9	0.3	0.5	0.5	0.9	0.0	-0.1	0.0	0.9	1.7	0.7	1.3	1.2	1.7	1.0	0.4	-0.1
Family relationship satisfaction	0.5	0.6	2.4	0.4	-0.3	-0.5	0.1	1.5	-0.6	-0.5	-0.5	-0.8	-0.5	-0.5	0.8	0.5	1.2	-0.5	-0.6	-0.7	-1.1	-1.4	-0.8	-0.4	-0.2	0.3	-1.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.6	0.2	-0.7	-0.8	-0.9	0.4	-0.9	-0.7	-0.8	-0.8	-0.8	-0.2	0.9	-0.0	1.2	-0.7	-1.0	-0.7	-0.8	-0.6	-0.5	-0.6	-0.5	-1.3	-0.9
Friendships satisfaction	0.5	0.6	2.6	1.0	0.6	0.7	0.9	1.6	0.6	0.7	0.4	0.5	0.7	0.6	0.8	1.3	0.6	0.9	0.1	0.1	0.3	-0.3	0.5	0.5	0.9	1.6	0.0
Tinnitus: Yes, now most or all of the time	0.5	0.5	1.8	-0.5	-1.4	-1.1	-0.3	-0.5	-1.1	-0.7	-0.5	-0.3	-0.5	-0.4	-1.1	-0.6	-0.7	-0.0	-0.7	-0.2	-0.8	-0.2	-0.0	-0.2	-0.6	-1.1	-1.3
High cholesterol (Self-reported)	0.5	0.9	2.2	-1.1	-0.6	-1.0	-1.0	-0.5	-0.9	-1.0	-0.7	-1.4	-0.9	-1.2	0.7	-1.1	0.2	-1.5	-0.6	-0.8	-1.0	-0.6	-1.2	-1.0	-1.0	-1.2	-0.4
Medication: Bendroflumethiazide	0.5	0.8	2.2	-0.1	-0.4	-0.9	-0.3	1.0	-0.9	-0.7	-1.3	-1.0	-0.6	-0.5	-0.3	-0.6	-0.1	0.5	-1.5	-1.3	-0.8	-1.2	-1.0	-1.3	-1.3	-1.1	-0.2
Leg fat percentage (left)	0.5	1.9	6.3	-0.7	-2.2	-1.1	-1.4	-2.4	-1.4	-1.3	-0.9	-0.9	-1.6	-1.1	-1.1	-1.5	-1.7	-1.0	-1.2	0.1	-1.3	-1.1	-0.6	-0.2	-1.6	-1.1	-2.5
Ever depressed for a whole week	0.5	0.7	4.9	-0.8	-0.6	-0.3	-0.1	0.0	-0.6	-0.5	0.2	0.1	-0.7	-0.7	0.5	-0.8	-1.8	-2.2	0.6	0.5	-1.0	0.1	-0.2	0.5	-0.1	0.4	-1.5
Depressed Affect (Nagel 2018)	0.4	0.9	5.0	1.0	0.1	0.4	0.9	2.0	-0.1	0.5	0.5	1.3	0.3	0.0	2.2	0.8	0.2	-0.4	0.7	1.6	0.2	0.4	1.0	1.6	0.3	0.4	-0.8
Systolic Blood Pressure	0.4	2.0	4.7	-0.5	-0.5	-1.2	-1.8	0.3	-0.9	-1.6	-1.3	-1.9	-1.5	-1.6	-1.3	-1.5	1.4	-1.9	-1.4	-2.2	-1.3	-1.1	-2.1	-2.1	-1.0	-0.7	-0.3
Hand grip strength (left)	0.4	1.1	8.5	-1.1	-1.5	-1.2	-0.3	-0.6	-1.3	-1.0	-0.8	-0.4	-0.9	-0.8	-1.0	-1.6	-2.9	-0.6	-0.8	-0.2	-1.0	-0.5	-0.4	-0.1	-0.8	-0.4	-1.3
Current tobacco smoking	0.4	0.7	1.7	-0.6	-0.9	-0.9	-0.6	-0.2	-1.0	-1.1	-0.6	-0.2	-1.1	-1.2	1.0	-1.3	-0.3	-1.1	-0.3	-0.3	-1.1	-0.4	-1.1	-0.4	-0.7	-0.6	-0.7
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.3	-0.5	-0.1	-0.5	-0.8	-0.1	-0.6	-0.5	-0.6	-0.7	-0.4	-0.6	0.2	-0.9	-0.5	-0.9	-0.4	-0.9	-0.7	-0.1	-0.8	-1.0	-0.4	-1.5	0.1
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.8	0.6	0.4	0.4	0.5	0.7	0.1	0.6	0.5	0.9	0.4	0.7	1.7	0.8	0.4	0.0	0.6	0.8	-0.0	0.1	0.5	0.8	0.3	1.1	-0.6
Fluid intelligence score	0.4	0.8	3.1	-1.0	-0.6	-0.8	-0.9	-1.1	-0.5	-0.5	-1.1	-1.2	-0.2	-0.7	-1.8	0.1	1.0	-0.1	-1.3	-1.2	-0.4	-1.2	-0.6	-0.9	-0.5	0.0	0.0
Impedance of arm (right)	0.4	1.9	9.1	0.2	2.0	0.3	0.3	3.0	0.6	0.3	0.2	0.1	0.4	-0.2	0.8	-0.1	2.5	-2.4	1.1	-1.6	0.3	1.5	-1.0	-1.7	0.6	-1.4	2.6
Impedance of arm (left)	0.4	1.9	8.1	0.2	2.1	0.5	0.6	2.8	0.9	0.5	0.4	0.4	0.5	0.1	0.6	0.1	2.6	-2.0	1.4	-1.4	0.5	1.9	-0.8	-1.4	0.9	-1.1	2.7
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	3.1	0.5	1.4	0.7	0.6	0.6	0.9	0.7	0.6	0.5	0.8	0.6	0.8	0.8	1.0	0.6	0.4	0.1	0.9	0.5	0.2	0.1	0.6	0.4	1.8
Commuting to job workplace: Walk	0.4	0.4	1.1	0.4	0.9	0.6	0.4	0.3	0.7	0.9	0.2	-0.1	1.0	0.9	-0.4	0.7	1.0	0.8	0.2	-0.4	0.7	0.1	0.5	-0.4	0.7	0.4	1.0
Smoking status: Current	0.4	0.7	1.5	-0.5	-1.0	-1.0	-0.6	-0.1	-1.0	-1.0	-0.7	-0.3	-1.0	-1.1	1.0	-1.2	-0.5	-1.0	-0.5	-0.4	-1.2	-0.7	-1.0	-0.4	-0.7	-0.6	-0.8
Miserableness	0.4	0.7	5.3	0.4	-0.0	0.3	0.3	0.8	-0.0	0.1	0.7	0.9	-0.1	-0.3	2.3	-0.1	-0.4	-1.6	0.9	1.5	0.1	0.6	0.5	1.4	0.6	0.7	-0.5
Ever smoked	0.4	0.7	5.3	-1.0	-0.3	-0.5	-0.2	-0.5	-0.4	-0.8	-0.0	-0.7	-0.8	-1.0	1.3	-0.9	-1.3	-2.3	0.4	-0.2	-0.8	0.4	-1.0	-0.5	-0.5	-0.8	0.0
Unable to work because of sickness or disability	0.4	0.6	2.2	-0.5	-0.5	-0.6	-1.5	-1.4	-0.7	-0.6	-0.5	0.2	-0.9	-0.5	-0.2	-0.1	1.4	-1.1	-0.3	-0.6	-0.7	-0.2	-0.7	-0.6	-0.6	-0.8	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.4	-0.2	-0.9	-0.9	-0.5	-0.3	-0.9	-1.1	-0.4	-0.1	-1.2	-0.6	0.5	-1.0	0.5	-0.9	-0.6	-0.0	-1.0	-0.5	-0.7	-0.3	-0.7	-0.7	-1.2
Heart disease (siblings)	0.4	0.4	1.3	-0.9	-0.2	-0.5	-0.1	-0.3	-0.5	-0.5	-0.7	-0.8	-0.4	-0.7	-0.1	-0.2	-0.8	-0.1	-0.7	-1.0	-0.5	-0.9	-0.8	-1.1	-0.9	-0.9	-0.3
Alzheimer’s Disease (including proxy)	0.3	0.4	1.5	-0.4	-0.7	-0.6	-0.5	0.0	-0.7	-0.4	-0.8	-0.6	-0.4	-0.4	-0.7	0.3	0.2	0.3	-1.0	-0.3	-0.5	-1.2	-0.3	-0.1	-0.4	0.9	-1.1
Verbal and Numeric Reasoning (VNR)	0.3	0.8	3.9	-1.1	-0.0	-0.8	-1.1	-0.9	-0.5	-0.5	-1.2	-1.2	-0.3	-0.6	-1.3	-0.0	2.0	-0.5	-0.9	-1.3	-0.4	-0.9	-0.7	-1.2	-0.7	-0.1	0.3
Sensitivity / hurt feelings	0.3	0.4	1.9	-0.5	0.3	0.6	0.4	-0.2	0.3	0.6	0.9	1.1	0.4	0.1	1.1	0.1	-0.1	0.3	1.1	1.4	0.3	0.7	0.6	1.2	0.4	0.6	-0.0
Hearing difficulty/problems: Yes	0.3	0.4	1.1	0.3	0.8	0.4	0.6	0.9	0.4	0.6	0.5	-0.1	0.7	0.8	0.6	0.9	0.6	1.1	0.4	-0.2	0.4	0.8	0.3	-0.0	0.6	-0.3	0.9
Ever had hysterectomy (womb removed)	0.3	0.4	1.1	0.2	0.4	0.4	0.9	0.8	0.4	0.5	0.7	0.0	0.6	0.7	0.8	-0.1	0.3	0.1	0.8	0.5	0.2	1.1	0.5	0.4	0.6	-1.0	0.5
Severe depression (siblings)	0.3	0.3	0.9	-0.3	-0.6	-0.6	-1.0	-0.2	-0.7	-0.5	-0.8	-0.5	-0.6	-0.5	-0.3	0.1	-0.1	0.0	-0.7	-0.7	-0.8	-0.6	-0.6	-0.5	-0.3	-0.0	-0.9
Stomach or abdominal pain in last month	0.3	0.4	1.5	-0.4	-1.1	-0.5	-0.6	-0.2	-0.7	-0.5	-0.4	-0.0	-0.4	-0.6	0.2	-0.9	-1.0	-0.4	-0.6	0.4	-0.3	-0.5	-0.1	-0.1	-1.0	-1.2	-1.0
Past tobacco smoking	0.3	0.6	4.4	0.8	0.3	0.4	0.3	0.3	0.4	0.7	0.1	0.6	0.8	1.0	-1.2	1.1	1.3	2.1	-0.1	0.2	0.8	-0.2	0.9	0.3	0.6	0.9	0.2
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.4	0.8	0.8	0.7	0.8	0.0	0.7	0.4	0.7	1.0	0.4	0.5	0.6	0.9	0.0	0.7	0.6	0.4	0.4	0.4	0.2	0.5	0.8	1.2	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.9	0.7	-0.8	-0.3	0.5	0.1	-0.3	-0.3	0.4	0.1	-0.0	-0.2	0.5	-0.7	-1.0	-1.4	0.1	0.8	-0.3	0.4	0.4	0.9	0.5	0.2	-0.5
Medication: Cholesterol lowering	0.3	0.4	3.0	-0.4	0.3	-0.0	0.4	1.0	0.0	0.3	0.3	-0.7	0.4	0.2	1.7	-0.2	1.6	0.1	0.6	0.1	0.1	0.8	0.2	0.1	0.3	-1.0	0.8
Birth weight of first child	0.3	0.5	5.8	0.6	0.3	0.5	-0.0	-0.8	0.4	0.1	0.5	0.3	0.2	0.0	0.6	-0.1	-2.4	0.6	0.2	0.7	0.2	-0.2	0.2	0.7	0.3	1.7	-0.1
Qualifications: College or University degree	0.3	1.0	2.5	1.1	1.0	1.2	0.5	-0.1	1.3	1.0	0.8	1.2	1.0	1.2	-0.6	1.1	1.1	1.0	0.4	0.6	1.1	0.4	0.8	0.7	1.1	1.6	1.3
Medication: Ibuprofen	0.3	0.4	1.6	0.8	-0.6	-0.1	0.6	-0.1	-0.1	0.0	0.7	0.4	0.2	0.1	0.6	-0.0	-0.7	-1.0	0.3	1.2	-0.0	0.5	0.7	1.3	0.6	0.8	-0.6
Medication: Seretide 50 evohaler	0.3	0.4	1.3	1.1	0.2	0.4	1.1	0.6	0.5	0.5	0.8	0.7	0.6	0.6	0.5	0.3	0.6	0.5	0.4	0.4	0.5	0.6	0.8	0.8	0.8	0.3	0.3
Age at last live birth	0.3	0.5	1.6	0.2	0.9	0.8	0.4	0.3	0.9	0.7	0.7	0.8	0.5	0.5	0.1	0.1	0.5	0.0	1.0	0.5	0.9	1.3	0.5	0.4	0.6	-0.1	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.1	-0.7	-0.6	-0.5	-0.6	-0.7	-0.6	-0.3	-0.8	-0.2	-0.3	-0.4	-0.8	-0.4	-0.5	0.2	-0.9	-0.2	-0.2	-1.0	-0.1	-0.2	-1.0	-0.1	-0.8
Loneliness, isolation	0.3	0.4	1.5	-0.0	-0.4	-0.7	-0.3	0.8	-0.9	-0.3	-1.0	0.2	-0.1	-0.6	1.0	1.0	0.1	-0.0	-0.9	-0.2	-0.5	-1.2	-0.1	-0.1	-0.5	-0.0	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.6	0.6	-0.5	-0.3	-0.9	-0.0	-0.4	-0.6	-0.1	-0.6	-0.6	-0.3	-0.4	-0.8	-1.2	0.4	-0.6	-0.4	-0.7	-0.6	-0.7	-0.3	-0.2	0.1	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	2.5	0.1	-0.4	-0.3	-0.1	0.2	-0.3	-0.4	0.0	0.5	-0.5	-0.4	1.4	-1.6	-0.5	-0.8	0.1	0.2	-0.4	-0.1	-0.2	0.2	-0.3	-0.9	-0.7
Illnesses of father: None of the above (group 1)	0.3	0.4	1.1	0.3	1.0	0.8	0.3	-0.0	0.9	0.4	0.7	0.4	0.3	0.3	0.7	0.1	0.8	-0.2	1.0	0.6	0.8	0.9	0.3	0.4	0.7	0.9	1.0
Wears glasses or contact lenses	0.3	0.3	0.8	0.9	0.5	0.7	0.6	0.1	0.8	0.4	0.9	-0.4	0.5	0.4	0.1	0.2	0.4	0.3	0.7	0.8	0.6	0.7	0.7	0.8	0.5	0.7	0.1
Commuting to job workplace: Public transport	0.3	0.4	3.4	-0.7	-0.6	-0.7	-0.7	-1.0	-0.7	-0.2	-0.6	-0.4	-0.2	-0.4	-1.8	0.4	-0.4	-0.1	-0.3	-0.5	-0.1	0.8	-0.2	-0.5	0.2	-0.1	0.4
Medication: Atorvastatin	0.3	0.4	1.5	-0.4	-0.5	-0.6	-0.6	0.2	-0.5	-0.8	-0.3	-0.2	-0.7	-0.4	0.4	-1.0	-0.7	-0.9	-0.2	-0.2	-0.8	-0.3	-0.4	-0.4	-0.9	-1.2	-1.0
Risk taking	0.3	0.4	2.3	-0.0	-1.1	-0.6	-0.2	0.1	-0.7	-0.6	-0.2	-0.3	-0.7	-0.8	0.7	-0.4	-1.5	-1.2	-0.1	0.2	-0.6	-0.3	-0.1	0.3	-0.0	-0.3	-1.3
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.8	0.2	0.2	0.3	0.4	-0.2	0.5	0.7	-0.1	-0.4	1.0	0.9	-0.9	0.1	-0.1	1.4	-0.4	-0.3	0.7	-0.4	0.8	0.0	0.3	0.4	0.5
Myopia	0.3	0.5	2.5	0.5	1.1	0.5	0.3	-0.3	0.7	0.5	0.3	0.6	0.8	0.6	-0.3	1.4	1.6	0.8	0.1	0.0	0.7	0.0	0.5	0.1	0.2	1.0	0.8
Pack years of smoking	0.3	0.4	1.1	-0.1	-0.7	-0.5	-0.9	-0.6	-0.5	-0.7	-0.5	0.3	-0.9	-0.3	0.5	-0.7	0.4	-0.2	-0.6	-0.3	-0.7	-0.7	-0.5	-0.6	-0.9	-1.1	-1.0
Alzheimer’s Disease (in father)	0.2	0.2	1.0	-1.0	0.6	0.1	-0.1	0.7	0.1	0.1	-0.2	-0.8	-0.0	-0.3	-0.1	0.6	1.0	-0.1	0.2	-0.8	-0.1	-0.4	-0.4	-0.6	-0.2	0.2	0.1
Ulcerative Colitis (UC)	0.2	0.4	2.2	0.5	0.4	0.4	0.6	1.2	0.3	0.5	0.6	1.5	0.4	0.6	0.5	0.7	-0.9	0.9	0.6	0.6	0.2	0.4	0.4	0.5	0.2	0.2	-0.1
Major Depression (MDD)	0.2	0.2	1.0	-0.2	-0.8	-0.5	-0.1	0.4	-0.7	-0.2	-0.3	-0.7	-0.0	-0.2	0.7	-0.3	0.4	-0.6	-0.2	0.3	-0.5	-0.2	0.2	0.3	-0.1	-0.6	-1.0
Rheumatoid Arthritis	0.2	0.2	0.9	0.3	0.4	0.5	0.4	0.9	0.4	0.3	0.5	0.3	0.1	0.2	0.5	0.6	0.7	-0.5	0.6	0.6	0.4	0.5	0.2	0.5	0.3	0.3	0.2
Maternal smoking around birth	0.2	0.2	1.4	0.8	-0.5	-0.3	0.0	1.2	-0.5	-0.3	-0.4	-0.3	-0.4	-0.4	-0.4	0.4	-0.1	-0.1	-0.8	-0.2	-0.3	-0.5	-0.5	0.1	-0.4	0.2	-0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.8	-0.5	-0.5	-0.3	-0.1	-0.4	-0.4	-0.4	-0.4	0.1	-0.4	-0.5	-0.2	0.2	-0.4	-0.2	-0.6	0.1	-0.2	-0.9	-0.4	-0.1	-0.6	0.6	-0.5
Supplements: Glucosamine	0.2	0.3	1.8	0.3	-0.4	0.4	0.6	0.3	0.5	0.3	0.4	-0.2	0.4	0.2	0.1	-0.1	-1.3	-0.2	-0.0	1.0	0.8	-0.2	0.9	0.9	-0.0	0.2	-0.3
Alcohol usually taken with meals	0.2	0.3	1.8	0.7	0.6	0.3	-0.2	-0.1	0.4	0.5	0.0	0.2	0.6	0.6	-0.5	0.4	1.4	0.1	0.0	-0.2	0.4	0.2	0.4	-0.0	0.6	-0.1	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	2.2	0.3	-0.4	-0.1	-0.1	0.7	-0.5	-0.1	-0.3	0.1	-0.2	-0.5	1.5	-0.1	-0.6	-0.2	-0.4	0.5	-0.4	-0.6	-0.3	0.1	-0.6	-0.9	-0.9
Hair/balding pattern: Pattern 3	0.2	0.4	1.8	0.7	0.4	0.5	0.7	1.3	0.4	0.6	0.2	0.4	0.8	0.7	0.9	0.1	0.3	0.5	-0.0	0.6	0.7	0.0	0.7	0.6	0.5	0.7	0.6
Number of live births	0.2	0.3	1.6	0.0	0.0	0.4	0.2	-0.5	0.3	0.5	0.6	0.1	0.6	0.8	1.3	-0.1	0.3	0.6	0.8	0.9	0.3	0.8	1.0	0.6	0.3	-0.5	0.2
Exposure to tobacco smoke at home	0.2	0.2	0.8	0.2	0.7	0.6	0.4	0.8	0.6	0.4	0.5	0.0	0.4	0.4	0.5	0.4	0.5	-0.1	0.4	-0.1	0.4	0.5	-0.0	-0.1	-0.1	-0.4	0.9
Pulse wave reflection index	0.2	0.3	1.2	0.1	0.3	-0.2	-0.4	-0.2	-0.1	0.3	-0.7	-0.2	0.3	0.3	0.2	0.9	1.0	0.3	-0.6	-1.1	0.2	-0.3	-0.2	-0.9	0.0	-0.5	0.6
Blood clot in the leg (DVT)	0.2	0.3	0.9	0.1	-0.6	-0.6	-0.3	-0.1	-0.7	-0.8	-0.1	0.1	-0.9	-0.4	0.7	-0.9	0.5	-0.6	-0.4	0.2	-0.8	-0.2	-0.5	-0.0	-0.4	-0.5	-1.0
Comparative body size at age 10	0.2	0.5	4.8	-0.3	-0.7	-0.7	-0.3	-0.6	-0.6	-0.3	-0.6	-0.3	-0.3	0.2	-1.4	0.3	2.2	0.1	-0.9	-0.7	-0.3	-0.1	-0.1	-0.5	-0.4	-0.5	-0.4
Illnesses of father: Heart disease	0.2	0.3	2.7	0.4	-0.0	-0.1	0.0	-0.2	-0.2	0.1	-0.4	0.0	0.3	0.5	0.1	0.2	-0.0	1.6	-1.0	-0.3	-0.3	-1.2	0.2	-0.2	-0.7	-0.0	-0.6
Smoking status: Previous	0.2	0.3	1.7	-0.6	-0.2	-0.1	-0.2	-0.3	-0.2	-0.3	0.0	-0.7	-0.5	-0.5	0.7	-0.7	-0.9	-1.3	0.1	-0.0	-0.5	0.3	-0.5	-0.2	-0.6	-1.1	-0.2
Intelligence (Savage-Jansen 2018)	0.1	0.4	3.5	-0.5	0.1	-0.5	-0.7	-0.6	-0.2	-0.4	-0.7	-0.9	-0.1	-0.6	-0.9	-0.0	1.9	-0.8	-0.6	-0.6	0.0	-0.5	-0.4	-0.5	-0.3	0.1	0.5
Schizophrenia (2018)	0.1	0.2	1.1	0.1	-0.2	-0.2	0.3	1.0	-0.3	-0.2	0.2	0.1	-0.3	-0.6	0.5	-0.7	0.8	-0.6	0.5	0.0	-0.2	1.0	-0.5	0.1	0.7	-0.1	0.5
Mean Putamen Volume	0.1	0.1	1.2	0.1	0.1	0.2	0.1	-0.1	0.3	0.2	0.0	0.2	0.3	0.3	0.5	0.1	-0.0	1.1	-0.2	-0.3	0.2	-0.1	0.1	-0.3	0.1	-0.0	0.3
Primary Biliary Cirrhosis	0.1	0.1	0.6	-0.5	-0.5	-0.1	-0.0	-0.3	-0.3	0.0	0.1	0.5	-0.0	-0.2	-0.2	-0.7	-0.4	-0.1	0.3	0.8	0.0	0.3	0.2	0.5	-0.2	-0.5	-0.6
Ulcerative Colitis	0.1	0.2	0.8	0.4	0.1	0.1	0.3	0.8	0.0	0.3	0.3	0.4	0.2	0.4	0.3	0.8	-0.9	0.6	0.2	0.5	0.0	0.3	0.3	0.3	0.1	-0.1	-0.2
Relative age of first facial hair	0.1	0.2	0.9	0.3	-0.3	-0.2	-0.3	-0.3	-0.2	-0.1	0.0	-0.2	-0.1	-0.0	-0.3	-0.8	-0.9	-0.8	0.0	0.2	-0.0	0.4	-0.1	0.0	-0.2	-1.0	-0.1
Systolic blood pressure, automated reading	0.1	0.4	1.8	-0.2	-0.1	-0.0	-1.1	-0.6	0.1	-0.3	-0.5	-1.2	-0.3	-0.3	-1.4	-0.6	0.8	0.5	-0.8	-1.1	-0.1	-0.5	-0.6	-0.9	-0.1	0.5	0.4
Vitamin and mineral supplements	0.1	0.1	1.1	0.2	0.4	-0.0	0.0	0.6	-0.1	-0.2	-0.1	0.4	-0.2	-0.2	0.8	0.3	1.0	-0.3	0.0	0.1	-0.1	-0.1	-0.2	0.1	-0.2	0.2	0.1
Relative age voice broke	0.1	0.2	1.6	-0.2	0.0	-0.0	-0.2	-0.2	-0.1	-0.1	0.0	0.7	-0.2	-0.2	-1.3	-0.2	0.2	-1.0	0.2	-0.0	-0.1	0.3	-0.3	0.1	-0.1	0.1	-0.1
Age when periods started (menarche)	0.1	0.3	1.4	0.9	0.3	0.6	0.4	0.5	0.5	0.4	0.7	0.4	0.4	0.2	-0.1	0.4	-0.1	0.4	0.5	1.2	0.6	0.4	0.6	1.2	0.2	1.0	0.3
Multivitamins +/- minerals	0.1	0.2	0.8	-0.1	-0.3	-0.3	-0.2	-0.2	-0.1	-0.2	-0.3	-0.6	-0.2	-0.1	-0.8	-0.1	-0.3	0.4	-0.5	-0.9	-0.3	-0.5	-0.4	-0.9	-0.1	-0.2	-0.2
Forced vital capacity (FVC)	0.1	0.3	2.0	-0.5	-0.1	0.2	-0.1	-0.7	0.2	-0.2	0.2	-0.6	-0.2	-0.6	-0.3	-0.3	-1.4	-1.0	0.2	0.4	0.2	-0.2	-0.1	0.4	0.2	0.8	0.1
Qualifications: None of the above	0.1	0.3	1.9	0.8	-0.0	-0.1	0.2	1.3	-0.3	-0.1	0.1	0.6	-0.6	0.1	1.4	-0.5	0.0	0.3	0.4	0.3	-0.4	0.4	-0.2	0.1	-0.3	-0.1	-0.7
Medication: Lansoprazole	0.1	0.2	1.2	0.2	-0.5	-0.3	-0.1	-0.4	-0.5	-0.2	-0.3	0.5	-0.2	-0.2	-0.1	0.2	-1.1	0.1	-0.2	0.4	-0.3	-0.2	0.1	0.4	-0.4	0.1	-0.7
Prospective memory result	0.1	0.1	1.1	0.4	0.3	0.3	-0.0	0.5	0.3	-0.0	0.2	-0.4	-0.1	0.1	0.7	0.2	1.0	0.7	0.1	0.2	0.1	0.1	-0.2	0.0	0.1	0.1	0.3
Gout (self-reported)	0.1	0.2	0.9	0.3	-0.2	-0.3	0.1	0.7	-0.6	-0.1	-0.6	0.0	0.0	-0.3	1.0	0.4	0.3	0.1	-0.7	-0.3	-0.3	-0.6	-0.1	-0.1	-0.2	0.1	-0.2
Forced vital capacity (FVC), Best measure	0.1	0.2	1.5	-0.4	-0.1	0.0	-0.5	-1.0	0.2	-0.4	0.0	-0.7	-0.4	-0.4	-0.7	-0.7	-1.2	-0.5	-0.3	-0.3	-0.0	-0.4	-0.4	-0.2	-0.1	0.2	0.2
Eye problems/disorders: None of the above	0.1	0.1	0.7	-0.1	0.3	0.0	-0.1	0.1	0.0	-0.3	-0.1	0.4	-0.4	-0.2	0.4	-0.5	0.3	0.2	-0.2	0.1	-0.3	-0.8	-0.1	-0.0	-0.5	0.1	-0.5
Medication: Allopurinol	0.1	0.2	1.3	0.1	-0.0	-0.2	0.2	1.0	-0.4	0.0	-0.4	0.5	0.1	-0.1	0.9	0.1	1.1	-0.0	-0.3	-0.3	-0.2	-0.3	0.0	-0.1	-0.2	0.3	-0.5
Suffer from ‘nerves’	0.1	0.2	0.8	-0.1	0.2	0.4	-0.4	-0.2	0.3	0.2	0.8	0.4	-0.0	0.1	0.7	-0.3	0.9	-0.4	0.9	0.8	0.2	0.7	0.3	0.7	0.4	0.1	0.0
Commuting to job workplace: Car/motor vehicle	0.1	0.2	0.8	0.8	0.1	0.5	0.4	0.9	0.6	0.0	0.5	-0.3	-0.1	0.1	0.8	0.1	-0.0	0.1	0.2	0.5	0.2	-0.4	0.1	0.3	-0.3	-0.2	-0.3
Mood swings	0.1	0.2	1.1	-0.3	-0.1	0.1	0.5	0.7	-0.1	0.1	0.3	0.3	0.2	-0.3	1.0	0.3	-0.3	-0.4	0.6	0.9	0.1	0.3	0.4	0.7	0.2	0.1	-0.6
Average weekly champagne plus white wine intake	0.1	0.1	0.6	0.3	-0.8	-0.6	0.3	0.2	-0.4	-0.4	-0.3	0.1	-0.1	-0.1	-0.6	-0.0	0.4	-0.4	-0.6	-0.2	-0.4	-0.4	-0.0	-0.1	0.0	-0.5	-0.5
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.4	-0.4	-0.2	0.1	0.5	0.0	0.2	0.1	-0.1	-0.5	0.3	0.1	-0.3	0.0	-0.5	0.5	-0.2	0.1	0.4	-0.3	0.5	0.2	-0.1	0.7	-0.2
Alcohol drinker status: Never	0.1	0.1	0.5	0.7	-0.2	0.1	0.2	-0.2	0.1	0.3	0.2	0.2	0.3	0.5	0.1	-0.2	-0.5	0.7	-0.1	0.7	0.2	-0.1	0.6	0.7	0.1	0.1	-0.3
Commuting to job workplace: Cycle	0.1	0.2	1.4	0.2	-0.0	0.2	0.2	-0.4	0.1	-0.2	0.3	1.2	-0.3	-0.2	-0.5	-0.4	-0.6	-0.6	0.1	0.6	-0.1	-0.0	-0.1	0.5	0.1	0.7	-0.5

Hub : Genes

PABPC4

Models

Trait associations