[Hub]/) : Traits : Blood Red Count :

chr7:49,817,957-51,215,365

Best TWAS P=6.42e-63 · Best GWAS P=7.47e-98 conditioned to 0.00188

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FIGNL1 0.21 0.21 enet 34 0.25 6.8e-30 -7.24 -8.7 5.3e-18 -0.43 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous FIGNL1 0.36 0.31 enet 37 0.43 5.3e-38 -8.02 -9.3 1.5e-20 -0.43 1.00 0.00 FALSE
3 GTEx Adipose Visceral Omentum FIGNL1 0.21 0.15 lasso 7 0.17 5.3e-09 -7.24 -8.9 4.5e-19 -0.45 0.98 0.02 FALSE
4 GTEx Adrenal Gland FIGNL1 0.43 0.40 enet 20 0.44 3.6e-17 -7.24 -9.6 8.8e-22 -0.43 1.00 0.00 FALSE
5 GTEx Artery Aorta FIGNL1 0.31 0.27 enet 13 0.30 9.4e-17 -7.24 -7.4 1.3e-13 -0.38 1.00 0.00 FALSE
6 GTEx Artery Coronary FIGNL1 0.30 0.07 enet 10 0.19 4.2e-07 8.60 -10.3 8.1e-25 -0.54 0.06 0.93 FALSE
7 GTEx Artery Tibial FIGNL1 0.31 0.26 lasso 12 0.28 2.5e-22 -7.88 -9.6 1.3e-21 -0.45 1.00 0.00 FALSE
8 GTEx Brain Caudate basal ganglia FIGNL1 0.18 0.13 lasso 3 0.12 2.4e-04 9.32 -9.4 3.4e-21 -0.50 0.16 0.38 FALSE
9 GTEx Brain Cerebellar Hemisphere FIGNL1 0.49 0.48 lasso 7 0.54 3.0e-16 9.32 -9.2 3.0e-20 -0.45 0.97 0.03 FALSE
10 GTEx Brain Cerebellum FIGNL1 0.54 0.54 enet 13 0.50 5.9e-17 -7.24 -8.7 2.9e-18 -0.42 1.00 0.00 FALSE
11 GTEx Brain Cortex FIGNL1 0.27 0.17 lasso 4 0.17 1.8e-05 9.32 -10.4 1.8e-25 -0.52 0.18 0.46 FALSE
12 GTEx Brain Frontal Cortex BA9 FIGNL1 0.24 0.19 enet 9 0.25 2.2e-07 9.32 -8.1 5.9e-16 -0.41 0.85 0.05 FALSE
13 GTEx Brain Hypothalamus FIGNL1 0.27 0.09 enet 26 0.18 5.9e-05 9.32 -10.2 2.6e-24 -0.51 0.18 0.67 FALSE
14 GTEx Breast Mammary Tissue FIGNL1 0.41 0.37 lasso 16 0.37 3.5e-20 -7.88 -8.6 8.6e-18 -0.43 1.00 0.00 FALSE
15 GTEx Cells EBV-transformed lymphocytes FIGNL1 0.31 0.28 lasso 15 0.33 1.6e-11 -7.24 -9.4 5.3e-21 -0.46 0.98 0.01 FALSE
16 GTEx Cells Transformed fibroblasts FIGNL1 0.18 0.10 lasso 7 0.17 1.2e-12 -5.44 -9.8 1.2e-22 -0.42 0.97 0.03 FALSE
17 GTEx Colon Sigmoid FIGNL1 0.21 0.21 lasso 4 0.25 2.0e-09 -7.24 -8.9 6.9e-19 -0.45 0.93 0.05 FALSE
18 GTEx Colon Transverse FIGNL1 0.32 0.28 enet 18 0.26 1.8e-12 -7.88 -8.5 2.1e-17 -0.39 1.00 0.00 FALSE
19 GTEx Esophagus Gastroesophageal Junction FIGNL1 0.40 0.23 enet 26 0.26 5.2e-10 -8.02 -9.5 1.9e-21 -0.43 0.89 0.10 FALSE
20 GTEx Esophagus Mucosa FIGNL1 0.34 0.31 lasso 9 0.32 3.3e-22 -7.88 -9.7 2.5e-22 -0.46 1.00 0.00 FALSE
21 GTEx Esophagus Muscularis FIGNL1 0.35 0.35 enet 20 0.35 5.0e-22 -7.88 -9.5 1.4e-21 -0.46 1.00 0.00 FALSE
22 GTEx Heart Atrial Appendage FIGNL1 0.30 0.28 lasso 7 0.27 1.2e-12 -7.24 -8.2 2.4e-16 -0.48 1.00 0.00 FALSE
23 GTEx Heart Left Ventricle FIGNL1 0.12 0.10 lasso 4 0.12 5.2e-07 -8.02 -8.3 9.6e-17 -0.44 0.92 0.04 FALSE
24 GTEx Lung FIGNL1 0.28 0.22 lasso 8 0.26 1.3e-19 -7.88 -11.5 2.0e-30 -0.55 1.00 0.00 FALSE
25 GTEx Nerve Tibial FIGNL1 0.36 0.36 enet 38 0.45 2.4e-35 -7.24 -9.3 1.9e-20 -0.44 1.00 0.00 FALSE
26 GTEx Ovary FIGNL1 0.48 0.34 enet 11 0.29 6.3e-08 -7.88 -7.6 3.5e-14 -0.41 0.73 0.11 FALSE
27 GTEx Pancreas FIGNL1 0.36 0.28 enet 27 0.25 8.2e-11 -7.88 -9.7 4.1e-22 -0.45 0.95 0.05 FALSE
28 GTEx Pituitary FIGNL1 0.27 0.28 lasso 4 0.24 9.2e-07 -7.24 -9.7 2.8e-22 -0.51 0.09 0.77 FALSE
29 GTEx Prostate FIGNL1 0.52 0.29 enet 13 0.40 2.6e-11 -5.00 -8.4 6.4e-17 -0.38 0.42 0.57 FALSE
30 GTEx Skin Not Sun Exposed Suprapubic FIGNL1 0.47 0.37 enet 24 0.43 1.8e-25 -5.44 -8.6 9.9e-18 -0.38 1.00 0.00 FALSE
31 GTEx Skin Sun Exposed Lower leg FIGNL1 0.46 0.41 enet 16 0.49 3.9e-46 -8.02 -9.2 3.0e-20 -0.45 1.00 0.00 FALSE
32 GTEx Small Intestine Terminal Ileum FIGNL1 0.21 0.23 lasso 4 0.22 1.3e-05 -5.00 -6.0 2.3e-09 -0.27 0.16 0.44 FALSE
33 GTEx Spleen FIGNL1 0.58 0.48 enet 19 0.52 1.9e-15 -7.88 -8.9 7.6e-19 -0.48 0.82 0.18 FALSE
34 GTEx Stomach FIGNL1 0.30 0.12 enet 20 0.23 1.7e-11 -7.24 -8.6 1.0e-17 -0.42 1.00 0.00 FALSE
35 GTEx Testis FIGNL1 0.35 0.24 enet 28 0.27 3.0e-12 -7.24 -9.1 9.3e-20 -0.42 1.00 0.00 FALSE
36 GTEx Thyroid FIGNL1 0.39 0.42 enet 11 0.42 7.5e-35 -7.24 -9.6 6.6e-22 -0.46 1.00 0.00 FALSE
37 GTEx Uterus FIGNL1 0.28 0.06 lasso 5 0.07 1.9e-02 -5.44 -6.0 2.8e-09 -0.33 0.14 0.06 FALSE
38 GTEx Vagina FIGNL1 0.37 0.05 lasso 7 0.22 1.1e-05 -7.24 -16.7 6.4e-63 -0.79 0.01 0.98 TRUE
39 METSIM Adipose FIGNL1 0.15 0.17 lasso 12 0.15 2.2e-21 -7.24 -8.0 1.3e-15 -0.43 1.00 0.00 TRUE
40 ROSMAP Brain Pre-frontal Cortex FIGNL1 0.29 0.30 lasso 6 0.32 1.1e-42 -7.24 -8.8 1.0e-18 -0.44 1.00 0.00 FALSE
41 YFS Blood FIGNL1 0.07 0.05 bslmm 472 0.05 2.6e-17 -7.24 -11.9 1.7e-32 -0.48 1.00 0.00 FALSE
42 The Cancer Genome Atlas Bladder Urothelial Carcinoma FIGNL1 0.06 0.02 enet 11 0.05 6.9e-05 9.07 -10.6 1.9e-26 -0.36 0.02 0.92 FALSE
43 The Cancer Genome Atlas Breast Invasive Carcinoma FIGNL1 0.07 0.06 enet 9 0.06 1.9e-12 -8.02 -8.5 1.3e-17 -0.44 1.00 0.00 FALSE
44 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FIGNL1 0.04 0.03 lasso 1 0.02 6.2e-03 -7.24 -7.2 4.6e-13 -0.39 0.02 0.35 FALSE
45 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FIGNL1 0.12 0.07 blup 67 0.12 1.3e-13 9.22 -9.9 2.9e-23 -0.42 0.12 0.88 FALSE
46 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FIGNL1 0.19 0.10 enet 14 0.15 1.1e-08 -8.02 -10.3 7.2e-25 -0.39 0.01 0.99 FALSE
47 The Cancer Genome Atlas Brain Lower Grade Glioma FIGNL1 0.24 0.16 enet 21 0.15 6.5e-17 -8.02 -7.6 2.7e-14 -0.31 1.00 0.00 FALSE
48 The Cancer Genome Atlas Lung Adenocarcinoma FIGNL1 0.03 0.01 blup 69 0.02 4.7e-03 -7.24 -8.4 3.3e-17 -0.45 0.06 0.38 FALSE
49 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FIGNL1 0.07 0.08 lasso 4 0.07 1.1e-08 -8.02 -8.9 3.4e-19 -0.46 0.92 0.08 FALSE
50 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IKZF1 0.03 0.00 blup 81 0.01 3.7e-02 -0.54 6.1 1.1e-09 0.35 0.02 0.05 FALSE
51 The Cancer Genome Atlas Prostate Adenocarcinoma DDC 0.10 0.07 lasso 4 0.09 3.2e-09 -7.24 8.1 6.3e-16 0.44 1.00 0.00 FALSE
52 The Cancer Genome Atlas Prostate Adenocarcinoma FIGNL1 0.14 0.15 blup 69 0.17 2.2e-17 -8.02 -8.6 9.9e-18 -0.42 1.00 0.00 FALSE
53 The Cancer Genome Atlas Soft Tissue Sarcoma FIGNL1 0.06 0.06 lasso 1 0.03 3.9e-03 9.32 -9.3 1.2e-20 -0.50 0.03 0.44 FALSE
54 The Cancer Genome Atlas Stomach Adenocarcinoma FIGNL1 0.05 0.00 blup 68 0.01 5.4e-02 -5.44 -6.7 2.2e-11 -0.36 0.02 0.17 FALSE
55 The Cancer Genome Atlas Thyroid Carcinoma FIGNL1 0.16 0.10 lasso 4 0.10 3.8e-10 9.32 -9.9 5.7e-23 -0.50 0.91 0.09 FALSE
56 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma FIGNL1 0.13 0.13 lasso 10 0.16 2.4e-05 8.46 -8.2 1.9e-16 -0.41 0.27 0.43 FALSE