[Hub]/) : Traits : Blood Red Count : ← →

chr7:49,817,957-51,215,365

Best TWAS P=6.42e-63 · Best GWAS P=7.47e-98 conditioned to 0.00188

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
38	GTEx	Vagina	FIGNL1	0.37	0.05	lasso	7	0.22	1.1e-05	-7.24	-16.7	6.4e-63	-0.79	0.01	0.98	TRUE
39	METSIM	Adipose	FIGNL1	0.15	0.17	lasso	12	0.15	2.2e-21	-7.24	-8.0	1.3e-15	-0.43	1.00	0.00	TRUE
41	YFS	Blood	FIGNL1	0.07	0.05	bslmm	472	0.05	2.6e-17	-7.24	-11.9	1.7e-32	-0.48	1.00	0.00	FALSE
24	GTEx	Lung	FIGNL1	0.28	0.22	lasso	8	0.26	1.3e-19	-7.88	-11.5	2.0e-30	-0.55	1.00	0.00	FALSE
42	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FIGNL1	0.06	0.02	enet	11	0.05	6.9e-05	9.07	-10.6	1.9e-26	-0.36	0.02	0.92	FALSE
11	GTEx	Brain Cortex	FIGNL1	0.27	0.17	lasso	4	0.17	1.8e-05	9.32	-10.4	1.8e-25	-0.52	0.18	0.46	FALSE
46	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FIGNL1	0.19	0.10	enet	14	0.15	1.1e-08	-8.02	-10.3	7.2e-25	-0.39	0.01	0.99	FALSE
6	GTEx	Artery Coronary	FIGNL1	0.30	0.07	enet	10	0.19	4.2e-07	8.60	-10.3	8.1e-25	-0.54	0.06	0.93	FALSE
13	GTEx	Brain Hypothalamus	FIGNL1	0.27	0.09	enet	26	0.18	5.9e-05	9.32	-10.2	2.6e-24	-0.51	0.18	0.67	FALSE
45	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FIGNL1	0.12	0.07	blup	67	0.12	1.3e-13	9.22	-9.9	2.9e-23	-0.42	0.12	0.88	FALSE
55	The Cancer Genome Atlas	Thyroid Carcinoma	FIGNL1	0.16	0.10	lasso	4	0.10	3.8e-10	9.32	-9.9	5.7e-23	-0.50	0.91	0.09	FALSE
16	GTEx	Cells Transformed fibroblasts	FIGNL1	0.18	0.10	lasso	7	0.17	1.2e-12	-5.44	-9.8	1.2e-22	-0.42	0.97	0.03	FALSE
20	GTEx	Esophagus Mucosa	FIGNL1	0.34	0.31	lasso	9	0.32	3.3e-22	-7.88	-9.7	2.5e-22	-0.46	1.00	0.00	FALSE
28	GTEx	Pituitary	FIGNL1	0.27	0.28	lasso	4	0.24	9.2e-07	-7.24	-9.7	2.8e-22	-0.51	0.09	0.77	FALSE
27	GTEx	Pancreas	FIGNL1	0.36	0.28	enet	27	0.25	8.2e-11	-7.88	-9.7	4.1e-22	-0.45	0.95	0.05	FALSE
36	GTEx	Thyroid	FIGNL1	0.39	0.42	enet	11	0.42	7.5e-35	-7.24	-9.6	6.6e-22	-0.46	1.00	0.00	FALSE
4	GTEx	Adrenal Gland	FIGNL1	0.43	0.40	enet	20	0.44	3.6e-17	-7.24	-9.6	8.8e-22	-0.43	1.00	0.00	FALSE
7	GTEx	Artery Tibial	FIGNL1	0.31	0.26	lasso	12	0.28	2.5e-22	-7.88	-9.6	1.3e-21	-0.45	1.00	0.00	FALSE
21	GTEx	Esophagus Muscularis	FIGNL1	0.35	0.35	enet	20	0.35	5.0e-22	-7.88	-9.5	1.4e-21	-0.46	1.00	0.00	FALSE
19	GTEx	Esophagus Gastroesophageal Junction	FIGNL1	0.40	0.23	enet	26	0.26	5.2e-10	-8.02	-9.5	1.9e-21	-0.43	0.89	0.10	FALSE
8	GTEx	Brain Caudate basal ganglia	FIGNL1	0.18	0.13	lasso	3	0.12	2.4e-04	9.32	-9.4	3.4e-21	-0.50	0.16	0.38	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	FIGNL1	0.31	0.28	lasso	15	0.33	1.6e-11	-7.24	-9.4	5.3e-21	-0.46	0.98	0.01	FALSE
53	The Cancer Genome Atlas	Soft Tissue Sarcoma	FIGNL1	0.06	0.06	lasso	1	0.03	3.9e-03	9.32	-9.3	1.2e-20	-0.50	0.03	0.44	FALSE
2	GTEx	Adipose Subcutaneous	FIGNL1	0.36	0.31	enet	37	0.43	5.3e-38	-8.02	-9.3	1.5e-20	-0.43	1.00	0.00	FALSE
25	GTEx	Nerve Tibial	FIGNL1	0.36	0.36	enet	38	0.45	2.4e-35	-7.24	-9.3	1.9e-20	-0.44	1.00	0.00	FALSE
9	GTEx	Brain Cerebellar Hemisphere	FIGNL1	0.49	0.48	lasso	7	0.54	3.0e-16	9.32	-9.2	3.0e-20	-0.45	0.97	0.03	FALSE
31	GTEx	Skin Sun Exposed Lower leg	FIGNL1	0.46	0.41	enet	16	0.49	3.9e-46	-8.02	-9.2	3.0e-20	-0.45	1.00	0.00	FALSE
35	GTEx	Testis	FIGNL1	0.35	0.24	enet	28	0.27	3.0e-12	-7.24	-9.1	9.3e-20	-0.42	1.00	0.00	FALSE
49	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FIGNL1	0.07	0.08	lasso	4	0.07	1.1e-08	-8.02	-8.9	3.4e-19	-0.46	0.92	0.08	FALSE
3	GTEx	Adipose Visceral Omentum	FIGNL1	0.21	0.15	lasso	7	0.17	5.3e-09	-7.24	-8.9	4.5e-19	-0.45	0.98	0.02	FALSE
17	GTEx	Colon Sigmoid	FIGNL1	0.21	0.21	lasso	4	0.25	2.0e-09	-7.24	-8.9	6.9e-19	-0.45	0.93	0.05	FALSE
33	GTEx	Spleen	FIGNL1	0.58	0.48	enet	19	0.52	1.9e-15	-7.88	-8.9	7.6e-19	-0.48	0.82	0.18	FALSE
40	ROSMAP	Brain Pre-frontal Cortex	FIGNL1	0.29	0.30	lasso	6	0.32	1.1e-42	-7.24	-8.8	1.0e-18	-0.44	1.00	0.00	FALSE
10	GTEx	Brain Cerebellum	FIGNL1	0.54	0.54	enet	13	0.50	5.9e-17	-7.24	-8.7	2.9e-18	-0.42	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FIGNL1	0.21	0.21	enet	34	0.25	6.8e-30	-7.24	-8.7	5.3e-18	-0.43	1.00	0.00	FALSE
14	GTEx	Breast Mammary Tissue	FIGNL1	0.41	0.37	lasso	16	0.37	3.5e-20	-7.88	-8.6	8.6e-18	-0.43	1.00	0.00	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	FIGNL1	0.47	0.37	enet	24	0.43	1.8e-25	-5.44	-8.6	9.9e-18	-0.38	1.00	0.00	FALSE
52	The Cancer Genome Atlas	Prostate Adenocarcinoma	FIGNL1	0.14	0.15	blup	69	0.17	2.2e-17	-8.02	-8.6	9.9e-18	-0.42	1.00	0.00	FALSE
34	GTEx	Stomach	FIGNL1	0.30	0.12	enet	20	0.23	1.7e-11	-7.24	-8.6	1.0e-17	-0.42	1.00	0.00	FALSE
43	The Cancer Genome Atlas	Breast Invasive Carcinoma	FIGNL1	0.07	0.06	enet	9	0.06	1.9e-12	-8.02	-8.5	1.3e-17	-0.44	1.00	0.00	FALSE
18	GTEx	Colon Transverse	FIGNL1	0.32	0.28	enet	18	0.26	1.8e-12	-7.88	-8.5	2.1e-17	-0.39	1.00	0.00	FALSE
48	The Cancer Genome Atlas	Lung Adenocarcinoma	FIGNL1	0.03	0.01	blup	69	0.02	4.7e-03	-7.24	-8.4	3.3e-17	-0.45	0.06	0.38	FALSE
29	GTEx	Prostate	FIGNL1	0.52	0.29	enet	13	0.40	2.6e-11	-5.00	-8.4	6.4e-17	-0.38	0.42	0.57	FALSE
23	GTEx	Heart Left Ventricle	FIGNL1	0.12	0.10	lasso	4	0.12	5.2e-07	-8.02	-8.3	9.6e-17	-0.44	0.92	0.04	FALSE
56	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	FIGNL1	0.13	0.13	lasso	10	0.16	2.4e-05	8.46	-8.2	1.9e-16	-0.41	0.27	0.43	FALSE
22	GTEx	Heart Atrial Appendage	FIGNL1	0.30	0.28	lasso	7	0.27	1.2e-12	-7.24	-8.2	2.4e-16	-0.48	1.00	0.00	FALSE
12	GTEx	Brain Frontal Cortex BA9	FIGNL1	0.24	0.19	enet	9	0.25	2.2e-07	9.32	-8.1	5.9e-16	-0.41	0.85	0.05	FALSE
51	The Cancer Genome Atlas	Prostate Adenocarcinoma	DDC	0.10	0.07	lasso	4	0.09	3.2e-09	-7.24	8.1	6.3e-16	0.44	1.00	0.00	FALSE
47	The Cancer Genome Atlas	Brain Lower Grade Glioma	FIGNL1	0.24	0.16	enet	21	0.15	6.5e-17	-8.02	-7.6	2.7e-14	-0.31	1.00	0.00	FALSE
26	GTEx	Ovary	FIGNL1	0.48	0.34	enet	11	0.29	6.3e-08	-7.88	-7.6	3.5e-14	-0.41	0.73	0.11	FALSE
5	GTEx	Artery Aorta	FIGNL1	0.31	0.27	enet	13	0.30	9.4e-17	-7.24	-7.4	1.3e-13	-0.38	1.00	0.00	FALSE
44	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FIGNL1	0.04	0.03	lasso	1	0.02	6.2e-03	-7.24	-7.2	4.6e-13	-0.39	0.02	0.35	FALSE
54	The Cancer Genome Atlas	Stomach Adenocarcinoma	FIGNL1	0.05	0.00	blup	68	0.01	5.4e-02	-5.44	-6.7	2.2e-11	-0.36	0.02	0.17	FALSE
50	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IKZF1	0.03	0.00	blup	81	0.01	3.7e-02	-0.54	6.1	1.1e-09	0.35	0.02	0.05	FALSE
32	GTEx	Small Intestine Terminal Ileum	FIGNL1	0.21	0.23	lasso	4	0.22	1.3e-05	-5.00	-6.0	2.3e-09	-0.27	0.16	0.44	FALSE
37	GTEx	Uterus	FIGNL1	0.28	0.06	lasso	5	0.07	1.9e-02	-5.44	-6.0	2.8e-09	-0.33	0.14	0.06	FALSE