Best TWAS P=6.61e-24 · Best GWAS P=5.6e-20 conditioned to 0.827
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | SEMA3C | 0.19 | 0.07 | bslmm | 532 | 0.18 | 6.9e-21 | 0.072 | 6.4 | 1.5e-10 | -0.12 | 1.00 | 0.00 | TRUE |
2 | METSIM | Adipose | CD36 | 0.05 | 0.03 | lasso | 3 | 0.05 | 2.1e-07 | 8.933 | -10.1 | 6.6e-24 | 0.50 | 0.03 | 0.97 | TRUE |
3 | NTR | Blood | CD36 | 0.06 | 0.01 | blup | 456 | 0.03 | 2.5e-11 | -3.526 | 7.0 | 2.7e-12 | -0.43 | 0.65 | 0.35 | FALSE |
4 | YFS | Blood | CD36 | 0.37 | 0.28 | enet | 53 | 0.35 | 9.4e-122 | -9.084 | 9.3 | 1.7e-20 | -0.90 | 0.00 | 1.00 | TRUE |