TWAS hub - CD36

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0620	0.0200	1.2e-04	0.035	0.035	0.031	0.034	0.034	3.7e-05	4.1e-05	1.1e-04	5.3e-05	4.7e-05
2	GTEx	Esophagus Mucosa	0.2530	0.0830	9.6e-04	0.024	NA	0.025	NA	0.021	8.9e-03	NA	8.3e-03	NA	1.5e-02
3	METSIM	Adipose	0.0462	0.0189	2.0e-03	0.034	0.017	0.037	0.025	0.045	7.0e-06	1.2e-03	2.7e-06	9.3e-05	2.1e-07
4	NTR	Blood	0.0555	0.0138	1.1e-09	0.011	0.034	0.016	0.032	0.020	1.0e-04	2.6e-11	4.9e-06	1.0e-10	2.8e-07
5	YFS	Blood	0.3706	0.0345	0.0e+00	0.282	0.315	0.353	0.325	0.345	3.3e-93	6.5e-106	9.4e-122	3.8e-110	3.7e-118
6	TCGA	Brain Lower Grade Glioma	0.0668	0.0252	2.6e-05	0.047	0.030	0.026	NA	0.039	4.4e-06	2.3e-04	5.2e-04	NA	2.8e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	3	4	5	6
Blood Platelet Count	4.5	52.0	97.8	7.5	6.2	-9.9	-9.0	6.2
Blood Red Count	4.3	41.9	102.0	-1.8	-10.1	7.0	9.3	-3.3
Supplements: Calcium	3.6	4.0	8.1	-2.2	-2.8	1.4	2.5	-1.7
Major Depression (MDD)	2.8	3.4	11.5	-0.2	0.4	-3.4	-2.0	-2.1
Unable to work because of sickness or disability	2.3	3.0	7.1	-2.5	-1.1	0.4	1.7	-2.7
Illnesses of father: None of the above (group 1)	2.2	2.7	7.6	-2.4	-1.7	-0.1	0.4	-2.8
Ever smoked	2.2	3.8	9.5	-2.5	-2.5	-0.2	0.9	-3.1
Alcohol usually taken with meals	2.0	3.2	10.8	2.4	1.3	0.8	-0.9	3.3
Age started oral contraceptive pill	2.0	2.5	6.1	-0.5	-2.2	1.5	2.5	-1.1
Depression (Nagel 2018)	1.9	2.8	8.5	-2.9	0.1	-0.7	-0.3	-2.8
Rheumatoid Arthritis	1.9	2.6	5.6	1.2	1.8	-1.2	-1.9	2.4
Average weekly spirits intake	1.9	2.3	6.8	0.1	-0.6	-2.6	-2.0	-1.6
Relative age of first facial hair	1.9	3.8	9.8	-0.7	1.5	-3.1	-2.9	-1.3
Mean Putamen Volume	1.8	2.1	5.5	1.8	2.3	-1.0	-1.2	1.2
Health satisfaction	1.7	2.2	4.3	-2.0	-1.4	-1.0	1.4	-2.1
Past tobacco smoking	1.6	2.9	6.9	1.8	2.4	1.3	-0.2	2.6
Medication: Blood pressure	1.6	2.9	5.7	2.4	1.4	-2.0	-1.9	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	8.2	0.7	0.7	-2.9	-1.5	-0.2
HDL Cholesterol	1.5	2.4	5.4	2.0	1.4	0.6	-1.7	2.3
Fasting Glucose	1.4	1.7	5.2	2.1	-0.0	0.3	-0.4	2.3
Medication: Co-codamol	1.4	1.6	2.4	-1.4	1.4	-1.6	-1.5	-1.0
Current tobacco smoking	1.4	2.3	8.2	-2.9	-0.9	0.6	1.0	-1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.9	5.6	-2.4	-0.5	0.4	1.2	-1.9
Happiness	1.4	1.7	6.4	-0.9	-2.5	0.3	1.2	-1.2
Illnesses of siblings: Diabetes	1.4	1.7	3.7	1.5	0.9	-1.2	-1.4	1.9
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	2.7	-1.5	1.4	-1.3	-1.6	-0.7
Smoking status: Current	1.4	2.2	7.5	-2.7	-0.8	0.7	1.2	-1.8
Waist Hip Ratio (WHR)	1.3	5.8	16.3	-0.0	-4.0	2.7	3.3	0.6
Sensitivity / hurt feelings	1.3	2.2	10.0	-0.3	0.1	-3.2	-1.7	0.0
Chronic bronchitis/emphysema (father)	1.3	1.5	5.3	1.9	0.2	-0.4	0.0	2.3
Ever highly irritable/argumentative for 2 days	1.3	1.6	5.6	-2.4	-1.6	0.5	0.1	-1.0
Shortness of breath walking on level ground	1.3	1.5	4.4	-1.1	-2.1	-0.2	1.3	-1.3
Mother’s age at death	1.3	1.6	4.9	0.6	0.6	-1.9	-2.2	-0.2
Irritability	1.3	2.3	4.8	-1.5	-2.2	1.2	1.0	-2.0
Commuting to job workplace: Cycle	1.3	1.6	7.6	-0.2	0.3	2.8	1.1	0.6
Myopia	1.3	1.8	4.0	-1.7	-2.0	-0.2	0.8	-1.9
Pain experienced in last month	1.3	2.1	7.2	1.9	1.3	0.3	-0.5	2.7
Smoking Status	1.2	2.9	7.1	-2.7	-1.2	-1.6	-0.1	-2.5
Maternal smoking around birth	1.2	1.8	3.7	-1.7	-1.8	-0.4	0.6	-1.9
Had other major operations	1.2	1.5	4.8	-1.1	-2.2	1.4	0.9	0.1
Loud music exposure frequency	1.2	1.3	4.3	-0.9	-0.9	-2.1	0.1	-1.3
Age at first live birth	1.2	2.1	5.5	-0.2	-1.3	2.4	2.3	0.4
Family relationship satisfaction	1.2	1.4	4.6	-1.4	-2.1	0.8	1.0	-0.7
Loneliness, isolation	1.2	1.7	5.2	-1.5	-1.2	0.1	1.2	-2.3
Supplements: Fish oil (including cod liver oil)	1.2	1.6	4.3	-1.5	-0.8	1.4	2.1	-0.5
Alcohol drinker status: Previous	1.2	1.4	4.5	-0.3	-2.1	0.7	1.8	-0.1
Schizophrenia (2014)	1.1	2.5	7.2	2.7	1.6	-0.8	-1.9	1.0
Financial difficulties in last 2 years	1.1	1.5	2.8	-1.3	-1.6	1.7	1.5	0.3
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	2.2	1.1	1.5	-1.4	-1.4	1.3
Length of working week for main job	1.1	1.3	2.7	-0.7	0.9	-1.6	-1.1	-1.6
Neck or shoulder pain in last month	1.1	1.6	3.3	-1.7	-0.0	-1.6	-0.8	-1.8
Osteoporosis (self-reported)	1.1	1.4	3.2	-1.2	-1.8	-0.9	-0.1	-1.7
Miserableness	1.1	1.9	5.9	-1.5	-2.4	-0.8	-0.2	-1.7
Body Mass Index (BMI) (2010)	1.0	1.4	4.5	2.1	1.0	0.1	0.4	1.7
Frequency of depressed mood in last 2 weeks	1.0	1.3	4.0	-1.9	0.1	-0.4	0.1	-2.0
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	6.6	2.6	1.0	1.2	-0.4	2.0
Supplements: Glucosamine	1.0	1.3	4.3	1.2	0.2	1.3	0.6	2.1
Medication: Levothyroxine sodium	1.0	1.8	6.6	0.5	-2.6	-0.2	1.5	-1.2
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	3.4	1.1	1.8	-0.1	-0.9	1.3
Eye problems/disorders: None of the above	1.0	1.1	3.9	0.3	-0.7	1.4	2.0	0.7
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	2.2	1.1	1.5	-0.1	-1.4	1.3
Medication: Atorvastatin	1.0	1.3	3.7	1.9	0.5	-1.3	-1.2	0.8
Illnesses of father: High blood pressure	1.0	1.2	4.7	0.7	0.1	2.2	1.3	0.7
Heart disease (siblings)	1.0	1.2	2.3	0.7	-1.5	-1.4	-1.5	-0.7
Supplements: Zinc	0.9	1.0	3.7	0.4	-0.9	1.0	1.9	-0.5
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	4.1	-0.4	-2.0	0.5	1.6	-1.8
Number of full brothers	0.9	1.1	2.5	-0.2	-1.6	-1.1	-0.9	-1.4
Medication for cholesterol	0.9	1.3	3.2	-1.3	0.6	-1.8	-1.7	-0.1
Hearing aid user	0.9	1.0	2.9	1.7	-0.6	0.7	0.1	1.5
Medication: Bendroflumethiazide	0.9	1.3	3.3	1.8	1.1	-0.8	-1.6	-0.0
Cholesterol lowering medication	0.9	1.4	3.1	1.8	-1.2	0.9	0.9	1.4
Crohns Disease (2017)	0.8	1.8	5.5	0.3	-2.4	0.1	2.1	-0.7
Irritable Bowel Disease (IBD)	0.8	1.8	5.0	0.3	-2.2	-0.3	2.0	-1.3
Hypothyroidism (self reported)	0.8	1.7	4.4	-0.4	-1.8	1.3	2.1	-1.1
Ever used hormone-replacement therapy (HRT)	0.8	1.0	4.6	0.5	-0.1	1.0	2.1	0.2
Angina	0.8	1.0	4.0	1.2	-2.0	-0.6	-0.4	0.1
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.6	-0.4	-1.6	1.6	0.3	-0.3
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	3.0	0.3	-1.1	-1.7	-1.1	-0.4
Qualifications: A levels/AS levels or equivalent	0.8	1.8	8.8	-0.4	-0.3	3.0	1.2	-0.2
Pulse wave Arterial Stiffness index	0.8	0.9	1.8	0.9	-0.6	0.9	1.3	1.3
Birth weight of first child	0.8	1.4	2.9	1.4	1.7	1.7	0.6	0.6
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	5.8	-0.1	0.0	2.4	1.2	0.6
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	2.8	-1.5	0.0	0.9	1.6	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	1.8	-1.3	-1.3	0.9	0.7	-1.3
Leg pain on walking	0.8	1.0	1.9	-0.7	-1.4	1.3	1.3	-0.5
Smoking status: Previous	0.8	1.2	3.1	-0.5	-1.3	-1.8	-0.7	-1.3
Handedness (chirality/laterality): Left-handed	0.8	0.9	2.6	0.0	1.3	0.9	0.7	1.6
Friendships satisfaction	0.8	1.0	2.8	1.2	-1.7	-0.8	0.8	0.6
Mineral and other dietary supplements	0.8	1.1	4.8	0.6	0.6	-1.1	-2.2	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	7.5	0.7	0.4	1.5	-0.6	2.7
Depressed Affect (Nagel 2018)	0.7	1.4	4.5	-1.0	-2.1	-0.9	-0.2	-1.4
Bipolar Disorder (2011)	0.7	0.7	1.8	-0.7	0.0	-0.4	-1.3	-1.3
Coronary Artery Disease (CAD)	0.7	0.8	2.6	0.6	1.0	-1.6	-0.7	-0.4
Medication for hormone replacement therapy	0.7	0.8	1.6	0.6	1.1	1.1	1.3	0.5
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.6	1.3	-1.1	1.1	0.7	0.1
Serious illness, injury or assault to yourself	0.7	0.8	3.9	-0.4	-2.0	-0.6	0.0	-0.7
Multivitamins +/- minerals	0.7	0.9	2.8	-0.9	-0.0	-0.2	1.7	-1.4
Hair/balding pattern: Pattern 3	0.7	1.0	4.3	1.0	0.2	0.4	-0.8	2.1
Mouth/teeth dental problems: Dentures	0.7	1.1	3.9	-1.4	-2.0	-0.2	0.7	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	4.1	-0.9	-0.2	-1.1	-2.0	-0.2
Exposure to tobacco smoke outside home	0.7	0.9	1.9	-1.1	-1.4	0.2	1.2	-0.8
Pulse wave peak to peak time	0.7	0.8	1.5	-0.8	0.7	-0.9	-1.1	-1.2
Angina (self-reported)	0.7	0.9	4.4	1.0	-2.1	-0.4	-0.1	0.2
Medication: Ibuprofen	0.7	0.8	1.7	-1.3	0.4	-1.2	1.2	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.2	0.9	0.1	1.2	0.8	1.5
Pulse rate, automated reading	0.7	2.2	6.4	0.8	-1.0	1.9	2.5	1.4
Supplements: Vitamin C	0.7	0.8	2.7	1.3	0.3	-0.3	-0.6	1.6
Illnesses of father: Heart disease	0.7	1.0	3.0	1.7	0.8	0.2	-0.6	1.5
Eye problems/disorders: Glaucoma	0.7	0.8	2.0	0.9	0.6	-1.2	-1.4	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	1.6	-1.2	-1.3	1.1	0.9	-0.7
Neuroticism (Nagel 2018)	0.6	1.4	3.9	-1.2	-2.0	-0.7	0.6	-1.4
Schizophrenia (2018)	0.6	1.3	4.5	2.1	0.9	-0.4	-1.2	0.8
LDL Cholesterol	0.6	1.0	2.3	-1.5	-0.8	-0.7	0.5	-1.5
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.8	0.8	1.0	-0.7	-1.3	0.6
Diabetes (mother)	0.6	0.7	1.9	-1.0	-0.6	0.9	1.4	-0.5
Fed-up feelings	0.6	1.2	3.5	-1.4	-1.9	-0.5	0.9	-0.7
Medication: Atenolol	0.6	0.7	3.2	0.5	1.8	0.4	-0.5	0.6
Sitting height	0.6	4.5	11.2	3.4	2.3	-0.5	-1.3	2.9
Hair/balding pattern: Pattern 2	0.6	0.7	2.8	1.3	1.7	-0.0	0.2	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.5	3.5	1.8	1.3	0.2	-0.7	1.9
Qualifications: None of the above	0.6	1.2	3.5	-0.6	-0.8	-1.9	-1.3	-1.0
Falls in the last year	0.6	0.9	2.4	-0.9	-1.2	1.6	0.0	-0.8
Medication: Ventolin 100micrograms inhaler	0.6	0.7	3.0	-0.3	0.8	0.1	1.7	0.8
Forced vital capacity (FVC), Best measure	0.6	2.3	8.0	1.9	0.9	1.0	-0.5	2.8
Number of children fathered	0.6	0.7	1.5	0.8	0.8	0.1	-1.2	1.1
Emphysema/chronic bronchitis	0.6	0.7	1.9	0.0	1.4	-1.2	-0.9	-0.3
Migraine (self-reported)	0.6	0.8	2.4	-1.5	-0.3	-0.3	-0.1	-1.4
Had major operations	0.6	0.7	2.1	0.8	0.6	-1.4	-1.1	0.2
Age at last live birth	0.6	0.9	2.5	-1.1	-1.0	0.8	1.6	-0.4
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.5	0.8	1.6	-1.0	-0.4	0.5
Average weekly red wine intake	0.6	0.9	2.1	1.1	0.7	0.4	-1.3	1.5
Commuting to job workplace: Walk	0.6	0.7	1.8	-0.7	-1.4	0.5	1.2	0.1
Eye problems/disorders: Cataract	0.6	0.7	1.6	-0.5	0.6	-1.3	-0.7	-1.1
Guilty feelings	0.6	0.8	2.9	-0.5	-1.7	0.5	1.1	-0.6
Ever taken oral contraceptive pill	0.6	0.7	2.3	0.2	1.3	-0.3	-1.5	0.1
Financial situation satisfaction	0.6	0.7	1.7	-1.3	-1.1	-0.2	1.1	-0.5
Alcohol drinker status: Never	0.6	0.7	1.6	0.1	1.1	-1.1	-1.3	0.6
Fractured/broken bones in last 5 years	0.6	0.7	2.3	-0.3	-1.5	1.1	0.6	-0.5
Diastolic blood pressure, automated reading	0.6	1.8	4.5	0.6	-1.6	1.6	2.1	-0.7
Ulcerative Colitis (UC)	0.5	0.9	2.6	-0.3	-1.1	-1.0	0.6	-1.6
Hearing difficulty/problems: Yes	0.5	0.7	2.1	1.4	-1.0	-1.0	-0.5	0.1
Ever had hysterectomy (womb removed)	0.5	0.6	1.8	1.3	0.1	-0.7	-1.1	-0.1
Townsend deprivation index at recruitment	0.5	0.7	1.7	-0.8	-0.9	-1.3	-0.3	-0.9
Taking other prescription medications	0.5	0.8	3.3	-0.7	-0.1	-0.5	0.8	-1.8
Age when periods started (menarche)	0.5	1.3	3.5	0.0	1.2	-1.7	-1.9	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.7	-1.3	-1.3	0.9	0.6	-0.1
Medication: Ramipril	0.5	0.6	1.6	1.2	-1.2	0.2	0.8	0.5
Father’s age at death	0.5	0.6	2.5	0.7	-0.1	1.6	0.6	0.7
Lung cancer (father)	0.5	0.5	2.0	1.0	-0.2	-0.3	-0.5	1.4
Medication: Paracetamol	0.5	0.8	2.7	-1.6	0.1	-1.1	-0.4	-0.7
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.4	1.6	-0.4	-0.1	-0.4	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.8	1.3	0.3	-0.6	-0.6	0.7
Knee pain experienced in last month	0.5	0.8	2.2	-1.0	-1.1	0.3	0.5	-1.5
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	3.4	0.7	1.8	-0.2	-0.3	1.0
Medication: Gliclazide	0.5	0.6	1.3	1.1	-1.1	1.0	0.1	-0.5
Commuting to job workplace: Public transport	0.5	0.6	1.9	1.0	-0.4	0.7	-0.6	1.4
Medication: Paracetamol	0.5	0.8	3.8	-1.9	-0.7	-0.4	0.6	-0.1
Ever depressed for a whole week	0.5	0.6	1.8	-0.6	-1.4	0.6	0.2	-1.0
Basal cell carcinoma (self-reported)	0.5	0.6	1.3	1.0	0.2	1.1	0.3	1.0
Pack years of smoking	0.5	0.7	2.3	0.9	-1.5	0.0	1.0	0.3
Bipolar Disorder (2018)	0.4	0.6	2.0	0.9	0.1	1.4	0.3	-0.7
Bipolar Disorder or Schizophrenia	0.4	1.1	4.8	2.2	0.8	0.6	-0.8	0.2
Alzheimer’s Disease (including proxy)	0.4	0.5	2.0	0.2	1.4	0.0	0.1	1.0
Primary Biliary Cirrhosis	0.4	0.5	1.3	-0.9	-0.5	-0.8	0.4	-1.1
Height	0.4	8.3	13.2	3.6	3.5	-2.0	-2.7	3.6
Lung FVC	0.4	1.8	5.7	1.1	0.8	1.9	-0.1	2.4
Vitamin and mineral supplements	0.4	0.5	2.0	0.5	0.6	0.2	-1.4	0.7
Stomach or abdominal pain in last month	0.4	0.4	1.4	-0.1	0.2	0.9	-0.6	1.2
Number of incorrect matches in round	0.4	0.7	1.8	-1.1	-0.7	0.2	0.5	-1.4
Had menopause	0.4	0.5	1.6	0.9	-0.2	-0.7	-1.3	-0.2
Forced vital capacity (FVC)	0.4	1.4	4.1	1.4	1.4	0.5	-0.4	2.0
Mouth/teeth dental problems	0.4	0.6	1.3	0.7	1.0	1.2	0.7	0.6
Illnesses of siblings	0.4	0.6	1.2	-0.5	0.4	1.0	1.1	-0.9
Neuroticism score	0.4	0.8	2.1	-0.8	-1.4	-1.4	-0.3	-0.5
Pulse rate	0.4	0.6	1.7	-1.3	0.1	0.7	1.2	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.0	-0.4	0.7	-0.9	0.7	1.0
Standing height	0.4	3.6	9.2	2.4	3.0	-1.6	-1.3	1.6
Exposure to tobacco smoke at home	0.4	0.4	1.2	0.8	0.1	0.7	-0.4	1.1
Hair/balding pattern: Pattern 4	0.4	0.9	2.5	-0.4	-1.6	0.6	0.7	-1.3
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	1.2	0.9	-0.5	-1.0	-1.1	0.4
Blood clot in the leg (DVT)	0.4	0.6	1.5	-0.5	-1.2	0.4	0.1	-1.2
Glaucoma (self-reported)	0.4	0.5	1.3	-0.2	0.1	-0.8	-1.2	-0.8
Gout (self-reported)	0.4	0.6	2.2	0.1	1.5	0.8	-0.5	-0.6
Birth weight	0.4	0.8	2.9	0.2	1.7	-0.4	-0.2	-1.3
Qualifications: College or University degree	0.4	1.3	3.2	1.1	0.3	1.8	1.0	1.4
Medication: Omeprazole	0.4	0.4	1.3	-1.2	-0.7	-0.1	-0.0	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	3.4	-0.3	1.8	-0.8	-0.8	-0.3
Mood swings	0.4	0.8	2.5	0.8	-1.6	-0.6	-1.2	0.2
Qualifications: nursing, teaching	0.4	0.6	2.3	-0.3	1.5	1.0	0.1	-0.2
Back pain experienced in last month	0.4	0.6	1.8	-0.9	-0.4	0.2	0.9	-1.4
Breast cancer (self-reported)	0.4	0.5	2.0	-0.3	-1.4	0.3	0.6	-0.7
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.0	-0.2	0.4	-0.9	-1.4	-0.1
Medication: Blood pressure	0.4	0.8	1.3	1.1	-1.2	1.1	0.9	-0.2
High cholesterol (Self-reported)	0.4	0.7	2.4	1.0	0.4	0.9	0.2	1.6
Schizophrenia vs Biploar Disorder	0.3	0.4	0.7	0.9	-0.8	-0.1	0.7	0.5
Worry (Nagel 2018)	0.3	0.6	1.4	-1.1	-1.2	-0.4	0.4	-0.8
Reaction Time	0.3	0.6	2.2	-0.4	-0.7	1.5	0.3	-0.6
Prostate Cancer	0.3	0.4	1.0	0.9	0.1	0.7	1.0	0.4
Age at First Birth	0.3	0.4	1.2	-0.2	1.1	1.0	0.3	-0.2
HbA1C	0.3	0.4	0.9	1.0	0.5	-0.6	-0.6	0.6
Lupus	0.3	0.5	0.9	0.9	-0.7	-0.8	-0.4	0.8
Neuroticism (2016)	0.3	0.5	1.5	-0.4	-0.7	0.2	1.2	-0.8
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.9	0.9	-0.1	-1.0	-0.0	0.8
BMI	0.3	1.8	6.4	-1.2	-2.5	0.3	0.9	-1.4
Allergy or Eczema	0.3	0.7	2.2	0.3	-0.2	1.5	0.4	1.2
Lung FEV1/FVC ratio	0.3	1.5	3.6	-1.9	-1.2	-0.7	0.4	-1.9
Severe depression (siblings)	0.3	0.3	0.7	0.8	0.4	0.3	-0.5	-0.9
Pack years adult smoking proportion	0.3	0.4	1.5	0.5	-1.2	0.0	0.9	0.1
Hand grip strength (right)	0.3	1.0	4.2	0.2	0.6	2.1	0.2	1.0
Average weekly fortified wine intake	0.3	0.3	0.9	-0.8	-0.4	0.3	-0.2	-1.0
Qualifications: CSEs or equivalent	0.3	0.4	2.0	-0.3	0.4	-1.4	-0.3	-0.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.6	-0.4	-1.2	0.4	0.1	-0.2
High blood pressure (mother)	0.3	0.4	0.9	0.7	0.4	-1.0	-0.6	0.7
Waist circumference	0.3	1.1	4.7	0.6	-2.2	0.2	1.1	-0.3
Nervous feelings	0.3	0.6	3.3	-0.1	-1.8	-0.4	0.4	-0.0
Heart attack	0.3	0.4	2.0	-0.0	-1.4	0.3	-0.2	-0.0
Time employed in main current job	0.3	0.3	0.9	-0.3	0.6	-0.9	-0.3	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.4	-0.3	-0.3	1.1	1.2	-0.5
Noisy workplace	0.3	0.4	1.0	0.8	1.0	-0.3	-0.2	0.6
Medication: Lansoprazole	0.3	0.4	1.5	0.1	1.2	-0.4	0.4	-0.6
Prospective memory result	0.3	0.4	1.0	1.0	0.7	-0.6	-0.5	-0.1
Illnesses of mother	0.3	0.4	1.3	0.2	1.0	1.2	0.3	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	3.1	0.7	0.2	1.4	0.2	1.8
Tense / ‘highly strung’	0.3	0.5	1.2	-1.1	-0.5	-0.8	0.1	-1.0
Leg fat percentage (right)	0.3	1.2	5.2	-0.6	-2.3	-0.5	0.8	-0.9
Comparative body size at age 10	0.3	0.9	2.0	-0.7	1.1	-1.2	-1.4	-0.5
Medication: Allopurinol	0.3	0.4	1.3	0.7	1.1	0.2	0.6	0.1
Overall health rating	0.3	0.6	2.0	-0.4	-0.3	-1.0	0.4	-1.4
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.4	-0.3	0.5	-0.3	-0.5	-1.2
Hypertension (Self-reported)	0.3	0.8	1.7	1.3	0.8	1.3	0.7	0.7
Long-standing illness, disability or infirmity	0.3	0.5	1.3	-0.7	-0.5	-0.6	0.7	-1.1
Average weekly champagne plus white wine intake	0.3	0.5	1.7	0.4	0.5	-0.3	-1.3	0.8
Leg fat percentage (left)	0.3	1.0	4.7	-0.2	-2.2	-0.6	0.9	-0.5
Average weekly beer plus cider intake	0.3	0.4	0.9	-0.8	-1.0	0.6	0.4	-0.5
Heart attack/myocardial infarction (self-reported)	0.3	0.3	1.9	0.1	-1.4	0.4	-0.1	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.2	-0.3	-0.9	-0.1	-0.3	-1.1
Alzheimer’s Disease (in mother)	0.2	0.3	0.6	0.2	0.4	0.4	0.8	0.8
Alzheimer’s Disease (in father)	0.2	0.3	0.7	0.2	0.7	-0.4	-0.4	0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.1	0.1	0.3	1.0	-1.0	-0.6
Breast Cancer	0.2	0.4	1.8	-0.3	-0.4	0.5	0.1	1.4
Crohns Disease (2012)	0.2	0.3	1.2	1.1	0.0	-0.8	0.0	0.4
Cardiovascular Disease	0.2	0.5	1.8	0.4	0.9	0.6	0.2	1.3
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.4	1.2	-0.3	0.6	-0.0	0.4
Neuroticism	0.2	0.5	1.1	-0.9	-1.1	-0.7	0.6	-0.5
Chronotype (morning person)	0.2	0.3	0.8	-0.9	0.2	-0.8	-0.7	0.2
Hand grip strength (left)	0.2	0.5	1.7	-0.2	1.0	-0.3	-1.3	0.4
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.6	0.2	0.4	-1.3	-0.2	-0.2
Trunk fat percentage	0.2	0.6	2.5	-0.3	-0.6	-1.6	-0.1	-1.0
Relative age voice broke	0.2	0.3	0.6	-0.5	0.7	-0.1	-0.7	-0.6
High blood pressure	0.2	0.7	1.6	1.1	0.9	1.2	0.5	0.7
Body mass index (BMI)	0.2	0.8	3.4	-0.4	-1.9	-0.3	0.4	-0.9
Pain all over the body in last month	0.2	0.2	0.5	-0.5	0.6	-0.7	0.6	-0.2
Diabetes (self-reported)	0.2	0.3	0.8	0.7	0.3	0.4	-0.4	0.9
Medication: Simvastatin	0.2	0.3	1.1	-0.0	-0.4	0.4	-0.1	1.1
Fluid intelligence score	0.2	0.4	1.0	-0.4	-0.9	0.4	-0.4	-1.0
Impedance of arm (right)	0.2	0.9	2.5	-0.3	1.5	-1.6	-0.7	0.1
Arm fat percentage (right)	0.2	0.7	1.8	-0.5	-1.4	-1.3	0.0	-0.8
Hip circumference	0.2	0.9	3.8	1.0	0.4	-1.9	-0.7	-0.0
Alcohol intake versus 10 years previously	0.2	0.3	1.4	-0.1	-0.3	0.1	-0.1	-1.2
Worrier / anxious feelings	0.2	0.5	2.3	0.2	-1.5	-0.3	-0.5	0.2
Number of live births	0.2	0.3	1.0	-0.3	-0.5	-1.0	-0.3	0.4
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	2.2	0.5	0.8	0.9	0.3	1.5
Medication: Cholesterol lowering	0.2	0.3	0.7	-0.3	-0.3	0.3	-0.9	0.7
Depression (self-reported)	0.2	0.3	0.8	-0.9	0.5	0.4	-0.5	-0.4
Breastfed as a baby	0.2	0.2	0.6	-0.2	-0.8	0.8	0.1	0.3
Pulse wave reflection index	0.2	0.3	1.1	0.6	-1.1	-0.3	0.2	-0.1
High blood pressure (siblings)	0.2	0.3	1.1	-0.7	-1.0	0.3	0.3	0.1
Body fat percentage	0.2	0.7	1.7	-0.4	-1.2	-1.3	0.1	-1.0
Worry too long after embarrassment	0.2	0.4	1.4	0.1	-0.3	-1.2	0.2	0.9
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.0	-0.5	0.2	-1.0	-0.3	-0.2
Medication: Seretide 50 evohaler	0.2	0.2	0.7	-0.7	-0.8	0.5	0.4	-0.0
Leg fat mass (right)	0.2	0.9	2.9	0.1	-1.7	-1.1	0.3	-1.0
Comparative height size at age 10	0.2	0.9	2.5	1.0	0.6	-0.0	1.2	1.6
Number of full sisters	0.2	0.2	0.8	-0.6	0.1	-0.3	-0.1	-0.9
Chest pain or discomfort	0.2	0.2	0.6	-0.6	-0.1	-0.7	-0.8	-0.1
Medication: Aspirin	0.2	0.3	0.9	0.1	-0.9	1.0	0.3	-0.0
Arm fat percentage (left)	0.2	1.0	2.2	-0.9	-1.5	-1.0	0.3	-1.3
Ever had bowel cancer screening	0.2	0.3	0.9	0.4	0.5	-0.3	-1.0	0.3
Osteoarthritis (self-reported)	0.2	0.2	0.4	0.3	0.6	-0.6	0.2	0.6
Number of self-reported non-cancer illnesses	0.2	0.3	1.1	0.4	0.4	-0.7	-1.0	-0.1
Wears glasses or contact lenses	0.2	0.3	1.0	1.0	-0.1	-0.5	-0.2	0.7
Medication: Lisinopril	0.2	0.2	1.0	-0.2	-0.1	-1.0	-0.6	0.2
Risk taking	0.2	0.2	0.5	-0.7	0.6	-0.1	0.2	-0.7
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.7	0.2	0.7	-0.3	-0.8	0.5
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.4	-0.9	-0.1	-1.2	-0.7	-0.8
Impedance of whole body	0.2	0.8	2.3	-0.2	1.5	-1.5	-0.5	0.2
Leg fat mass (left)	0.2	0.8	2.5	0.3	-1.6	-1.2	0.4	-0.7
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.1	0.1	-0.1	0.2	-1.0	-1.1
Ovarian Cancer	0.1	0.1	0.4	-0.6	-0.2	0.2	-0.0	-0.2
Triglycerides	0.1	0.1	0.4	-0.6	-0.5	-0.3	0.0	-0.3
Ulcerative Colitis	0.1	0.2	0.3	0.2	-0.6	-0.5	0.4	-0.4
Blood Eosinophil Count	0.1	0.5	1.7	1.3	-0.8	-0.6	-0.2	0.6
Blood White Count	0.1	0.7	2.5	-0.0	0.0	-1.2	1.6	-0.3
Heel T-Score	0.1	1.2	6.2	-0.1	2.5	0.4	-0.5	0.7
Respiratory disease	0.1	0.2	0.6	0.4	0.4	-0.8	0.6	0.0
Hair Pigment	0.1	2.4	8.5	-0.8	1.9	-2.9	-0.9	-1.0
Number of treatments/medications taken	0.1	0.2	0.5	-0.5	0.1	-0.5	0.4	-0.7
Systolic blood pressure, automated reading	0.1	0.3	1.1	0.9	-1.0	-0.0	-0.1	0.3
Medication: Metformin	0.1	0.1	0.5	0.5	0.3	0.7	0.1	0.2
Impedance of leg (right)	0.1	0.5	2.1	-0.4	0.2	-1.4	-0.7	-0.3
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.8	-0.4	-0.9	-0.1	-0.0	0.5
Impedance of leg (left)	0.1	0.5	2.7	-0.1	0.4	-1.7	-0.4	0.3
Leg predicted mass (left)	0.1	0.3	0.8	0.9	0.6	-0.6	-0.6	-0.2
Trunk fat mass	0.1	0.5	2.1	0.1	-0.4	-1.5	-0.1	-0.7
Hearing difficulty/problems with background noise	0.1	0.2	0.7	0.3	0.1	-0.8	-0.4	-0.5
Allergy	0.1	0.2	0.4	-0.0	0.6	0.5	0.3	-0.6
Weight	0.1	0.3	0.9	0.8	-0.4	-0.9	-0.2	-0.1
Trunk fat-free mass	0.1	0.3	0.6	0.8	0.7	-0.4	-0.6	0.5
Asthma	0.1	0.2	0.7	0.5	0.2	-0.8	-0.1	0.1
Impedance of arm (left)	0.1	0.6	2.1	-0.5	1.5	-1.1	-0.6	-0.2
Arm fat mass (right)	0.1	0.4	1.3	0.0	-0.9	-1.1	-0.1	-0.6
Trunk predicted mass	0.1	0.4	0.6	0.7	0.7	-0.5	-0.8	0.5
Peak expiratory flow (PEF)	0.1	0.3	0.7	-0.7	0.6	-0.2	-0.2	0.9
Headache pain in last month	0.1	0.2	0.6	-0.5	-0.3	0.8	-0.2	0.3
Medication: Amlodipine	0.1	0.1	0.3	0.3	-0.0	0.4	-0.6	-0.5
Wheeze or whistling in the chest in last year	0.1	0.3	0.8	0.8	-0.1	-0.9	-0.5	-0.2
Medication for pain relief, constipation, heartburn	0.1	0.1	0.2	0.5	-0.3	0.4	0.4	-0.3
Mean time to correctly identify matches	0.1	0.1	0.5	0.4	-0.4	0.7	-0.1	0.0
Heart disease (mother)	0.1	0.2	0.4	0.2	-0.7	0.2	-0.5	0.4
Whole body fat mass	0.1	0.6	1.7	-0.2	-0.8	-1.3	-0.0	-1.0
Suffer from ‘nerves’	0.1	0.1	0.4	-0.6	-0.2	-0.6	-0.2	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.4	0.4	0.6	-0.5	0.2	0.3
Leg fat-free mass (right)	0.1	0.3	1.0	1.0	0.7	-0.6	-0.5	0.2
Diabetes diagnosed by doctor	0.1	0.1	0.3	0.3	0.2	0.3	-0.4	0.6
Leg predicted mass (right)	0.1	0.3	0.8	0.9	0.6	-0.5	-0.4	0.1
Arm fat mass (left)	0.1	0.5	1.0	-0.3	-1.0	-1.0	0.1	-0.8
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.3	0.0	0.2	-0.3	0.6	-0.2
Basal metabolic rate	0.1	0.3	0.8	0.9	0.4	-0.7	-0.5	0.2
Arm fat-free mass (left)	0.1	0.4	1.3	1.2	0.2	-0.6	-0.5	0.6
Number of operations (self-reported)	0.1	0.2	0.8	0.3	-0.9	-0.0	0.2	0.3
Arm predicted mass (left)	0.1	0.3	1.1	1.1	-0.1	-0.6	-0.2	0.6
Systolic Blood Pressure	0.0	0.2	0.9	0.7	-0.1	-0.9	0.1	0.1
Tanning	0.0	0.3	0.9	0.2	0.4	0.8	0.9	0.0
Diabetes (father)	0.0	0.0	0.1	-0.2	0.2	0.3	-0.1	0.1
Leg fat-free mass (left)	0.0	0.2	0.5	0.7	0.5	-0.6	-0.5	-0.3
Arm fat-free mass (right)	0.0	0.3	1.2	1.1	0.4	-0.3	-0.2	0.2
Arm predicted mass (right)	0.0	0.1	0.5	0.7	0.1	-0.1	-0.0	0.1
Alcohol intake frequency.	0.0	0.1	0.3	0.1	-0.1	0.6	0.1	-0.3
Whole body fat-free mass	0.0	0.3	0.7	0.8	0.6	-0.5	-0.6	0.2
Asthma (self-reported)	0.0	0.1	0.4	0.4	-0.2	-0.6	0.0	0.1
Medication: Aspirin	0.0	0.0	0.1	-0.0	-0.2	0.3	0.0	-0.3
Whole body water mass	0.0	0.2	0.7	0.8	0.5	-0.4	-0.4	0.3

Hub : Genes

CD36

Models

Trait associations