[Hub]/) : Traits : Blood Red Count :

chr7:90,624,416-92,918,588

Best TWAS P=9.51e-19 · Best GWAS P=3.13e-18 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CYP51A1 0.05 0.08 lasso 5 0.06 2.4e-08 -8.10 7.9 3.4e-15 0.18 0.20 0.80 FALSE
2 CommonMind Brain Pre-frontal Cortex KRIT1 0.04 0.01 blup 318 0.02 1.2e-03 -8.33 5.6 2.8e-08 0.18 0.16 0.73 FALSE
3 GTEx Adrenal Gland GATAD1 0.40 0.22 lasso 7 0.25 2.0e-09 -2.56 5.5 5.1e-08 0.42 0.65 0.10 TRUE
4 GTEx Artery Aorta AC000120.7 0.06 0.09 lasso 4 0.08 3.4e-05 -8.30 8.3 1.4e-16 0.17 0.19 0.80 FALSE
5 GTEx Artery Coronary AC000120.7 0.07 0.04 lasso 4 0.02 6.8e-02 -7.88 8.5 2.3e-17 0.18 0.12 0.44 TRUE
6 GTEx Artery Tibial AC000120.7 0.08 0.06 lasso 4 0.06 3.2e-05 -7.67 7.8 4.4e-15 0.24 0.25 0.74 FALSE
7 GTEx Brain Cortex AC000120.7 0.12 0.08 enet 16 0.07 7.0e-03 -8.11 7.0 2.5e-12 0.23 0.09 0.35 FALSE
8 GTEx Cells Transformed fibroblasts AC000120.7 0.04 0.05 lasso 4 0.04 5.2e-04 -7.91 8.3 1.0e-16 0.16 0.20 0.76 FALSE
9 GTEx Colon Sigmoid AC000120.7 0.09 0.08 lasso 3 0.07 2.2e-03 -6.96 6.5 8.5e-11 0.15 0.16 0.51 TRUE
10 GTEx Colon Transverse KRIT1 0.32 0.00 lasso 8 0.00 3.7e-01 -8.30 7.0 3.7e-12 0.03 0.08 0.30 FALSE
11 GTEx Colon Transverse AC000120.7 0.09 0.04 lasso 5 0.01 9.4e-02 -8.19 8.2 3.6e-16 0.17 0.12 0.50 FALSE
12 GTEx Esophagus Mucosa AKAP9 0.04 0.03 lasso 15 0.02 2.7e-02 -8.24 -8.2 2.7e-16 -0.17 0.14 0.83 FALSE
13 GTEx Esophagus Muscularis FAM133B 0.07 0.01 enet 2 0.01 1.2e-01 8.71 8.2 2.0e-16 0.94 0.01 0.89 TRUE
14 GTEx Heart Atrial Appendage AKAP9 0.06 0.01 enet 11 0.02 4.5e-02 -7.92 8.1 5.8e-16 0.17 0.11 0.66 FALSE
15 GTEx Lung AC000120.7 0.04 0.03 lasso 3 0.01 4.8e-02 -8.17 8.2 1.5e-16 0.17 0.16 0.65 FALSE
16 GTEx Muscle Skeletal CYP51A1 0.10 0.18 enet 21 0.17 5.0e-16 -8.30 8.4 4.8e-17 0.19 0.10 0.90 FALSE
17 GTEx Muscle Skeletal AC000120.7 0.05 0.01 enet 10 0.01 5.4e-02 -8.25 6.1 1.2e-09 0.15 0.14 0.49 TRUE
18 GTEx Nerve Tibial ANKIB1 0.04 0.04 enet 2 0.02 8.5e-03 -7.30 8.2 2.7e-16 0.15 0.13 0.71 FALSE
19 GTEx Nerve Tibial AKAP9 0.03 0.05 lasso 2 0.03 2.7e-03 -8.25 -8.2 1.6e-16 -0.17 0.12 0.75 FALSE
20 GTEx Pancreas AC000120.7 0.05 0.03 enet 12 0.02 4.4e-02 -5.53 7.0 2.8e-12 0.21 0.14 0.53 FALSE
21 GTEx Prostate AC000120.7 0.13 0.09 lasso 3 0.09 2.8e-03 -8.33 8.3 1.5e-16 0.17 0.08 0.43 FALSE
22 GTEx Skin Sun Exposed Lower leg AC000120.7 0.06 0.00 enet 24 0.00 7.9e-01 -4.20 5.9 4.1e-09 0.31 0.10 0.34 FALSE
23 GTEx Spleen PEX1 0.18 0.00 enet 38 0.05 2.4e-02 -8.32 5.9 3.9e-09 0.16 0.06 0.36 FALSE
24 GTEx Spleen AC000120.7 0.10 0.07 lasso 5 0.04 3.9e-02 -8.17 8.2 2.3e-16 0.17 0.09 0.45 FALSE
25 GTEx Testis AC000120.7 0.05 0.03 enet 24 0.01 8.5e-02 -7.74 7.0 1.7e-12 0.15 0.12 0.60 FALSE
26 GTEx Thyroid AC000120.7 0.04 0.01 lasso 6 0.02 2.2e-02 -7.13 5.9 3.7e-09 0.16 0.17 0.51 TRUE
27 ROSMAP Brain Pre-frontal Cortex ANKIB1 0.03 0.03 enet 8 0.03 2.6e-04 -8.37 8.2 2.6e-16 0.15 0.06 0.92 FALSE
28 ROSMAP Brain Pre-frontal Cortex CYP51A1 0.04 0.02 blup 287 0.03 4.7e-05 -7.89 5.7 9.7e-09 0.14 0.23 0.76 FALSE
29 ROSMAP Brain Pre-frontal Cortex KRIT1 0.04 0.03 bslmm 311 0.01 9.0e-03 -8.39 -7.4 1.7e-13 -0.32 0.09 0.89 TRUE
30 ROSMAP Brain Pre-frontal Cortex MTERF 0.04 0.00 blup 375 0.02 7.5e-04 0.91 -5.7 1.3e-08 -0.12 0.09 0.37 FALSE
31 YFS Blood CYP51A1 0.03 0.06 blup 288 0.05 1.2e-16 -8.13 8.8 9.5e-19 0.28 0.17 0.83 TRUE
32 The Cancer Genome Atlas Breast Invasive Carcinoma CYP51A1 0.01 0.02 blup 51 0.02 2.0e-04 -8.29 8.5 1.9e-17 0.18 0.05 0.92 FALSE
33 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CYP51A1 0.07 0.04 lasso 2 0.04 4.3e-05 -8.37 8.3 1.2e-16 0.15 0.02 0.98 FALSE
34 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CYP51A1 0.04 0.05 blup 51 0.05 9.4e-07 -8.25 8.4 4.5e-17 0.18 0.06 0.94 FALSE
35 The Cancer Genome Atlas Brain Lower Grade Glioma CYP51A1 0.01 0.01 blup 51 0.01 1.2e-02 -8.17 8.4 4.3e-17 0.18 0.04 0.62 FALSE
36 The Cancer Genome Atlas Lung Adenocarcinoma CYP51A1 0.03 0.03 enet 12 0.03 1.2e-04 -8.39 8.6 8.4e-18 0.17 0.02 0.95 FALSE
37 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LOC401387 0.04 0.00 lasso 1 0.00 1.6e-01 -8.11 -8.1 5.1e-16 -0.19 0.03 0.58 FALSE
38 The Cancer Genome Atlas Prostate Adenocarcinoma MTERF 0.03 0.03 blup 47 0.04 1.2e-04 -7.37 -8.0 1.3e-15 -0.17 0.03 0.95 FALSE