[Hub]/) : Traits : Blood Red Count :

chr8:47,421,087-49,584,958

Best TWAS P=1.81e-13 · Best GWAS P=5.06e-18 conditioned to 1.56e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KIAA0146 0.06 0.07 lasso 5 0.07 3.0e-09 5.7 -6.7 2.4e-11 -0.83 0.54 0.46 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100287846 0.02 0.00 blup 149 0.01 2.9e-02 7.4 -6.9 6.2e-12 -0.85 0.10 0.50 FALSE
3 CommonMind Brain Pre-frontal Cortex MCM4 0.29 0.10 enet 36 0.17 1.7e-20 7.7 -7.4 1.8e-13 -0.61 0.01 0.99 TRUE
4 GTEx Adipose Visceral Omentum RP11-697N18.3 0.10 0.12 enet 11 0.11 3.1e-06 4.0 6.3 3.2e-10 0.72 0.10 0.88 FALSE
5 GTEx Adrenal Gland RP11-697N18.3 0.14 0.01 enet 13 0.08 6.6e-04 7.7 5.5 3.3e-08 0.76 0.04 0.73 FALSE
6 GTEx Brain Frontal Cortex BA9 SPIDR 0.19 0.12 lasso 18 0.14 1.9e-04 5.7 -6.4 1.6e-10 -0.78 0.24 0.55 FALSE
7 GTEx Esophagus Mucosa SPIDR 0.09 0.01 enet 17 0.06 1.4e-04 7.1 -6.6 4.3e-11 -0.68 0.17 0.39 FALSE
8 GTEx Testis MCM4 0.11 0.00 enet 31 0.01 1.1e-01 4.6 -5.4 6.1e-08 -0.58 0.04 0.70 FALSE
9 ROSMAP Brain Pre-frontal Cortex MCM4 0.20 0.02 bslmm 184 0.08 2.8e-10 4.6 -5.7 1.4e-08 -0.38 0.05 0.94 FALSE
10 ROSMAP Brain Pre-frontal Cortex SPIDR 0.08 0.07 enet 14 0.07 1.3e-09 5.4 -6.4 1.9e-10 -0.72 0.90 0.10 FALSE
11 ROSMAP Brain Pre-frontal Cortex RP11-1134I14.8 0.06 0.04 blup 125 0.05 1.9e-07 8.3 -7.1 1.2e-12 -0.89 0.05 0.95 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma MCM4 0.02 0.01 enet 4 0.02 1.4e-04 6.1 -6.6 5.0e-11 -0.49 0.01 0.81 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma KIAA0146 0.03 0.01 blup 42 0.02 2.4e-03 7.3 -5.3 1.3e-07 -0.56 0.01 0.87 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma MCM4 0.05 0.04 lasso 2 0.04 5.1e-05 5.3 -6.4 1.4e-10 -0.56 0.01 0.80 FALSE
15 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MCM4 0.19 0.10 enet 1 0.10 3.1e-05 5.3 -5.3 1.0e-07 -0.54 0.02 0.80 FALSE