Best TWAS P=1.9e-12 · Best GWAS P=9.57e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | CA8 | 0.14 | 0.12 | enet | 10 | 0.13 | 5.5e-10 | 6.7 | 7.0 | 1.9e-12 | 0.95 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Small Intestine Terminal Ileum | CA8 | 0.28 | 0.09 | lasso | 4 | 0.12 | 1.3e-03 | 1.2 | 5.2 | 2.5e-07 | 0.71 | 0.04 | 0.74 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CA8 | 0.05 | 0.04 | blup | 93 | 0.03 | 6.7e-04 | 6.7 | 5.6 | 2.8e-08 | 0.88 | 0.02 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CA8 | 0.06 | 0.02 | blup | 93 | 0.04 | 8.9e-06 | 6.8 | 6.1 | 1.1e-09 | 0.85 | 0.01 | 0.98 | FALSE |