[Hub]/) : Traits : Blood Red Count :

chr8:95,139,766-96,825,195

Best TWAS P=8.44e-22 · Best GWAS P=3.3e-18 conditioned to 0.00358

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous NDUFAF6 0.10 0.02 lasso 8 0.04 1.4e-04 8.3 -7.1 1.3e-12 -0.32 0.06 0.81 FALSE
2 GTEx Adipose Visceral Omentum CCNE2 0.16 0.08 enet 20 0.06 5.8e-04 8.3 -8.2 3.1e-16 -0.50 0.04 0.95 FALSE
3 GTEx Artery Aorta TP53INP1 0.08 0.02 enet 18 0.03 9.7e-03 -5.2 6.7 1.7e-11 0.71 0.08 0.80 FALSE
4 GTEx Artery Tibial INTS8 0.11 0.11 lasso 1 0.09 7.1e-08 6.6 -6.7 3.0e-11 -0.35 0.96 0.02 FALSE
5 GTEx Brain Cerebellum NDUFAF6 0.28 0.13 lasso 7 0.14 5.8e-05 8.3 -8.3 7.6e-17 -0.42 0.03 0.95 FALSE
6 GTEx Cells EBV-transformed lymphocytes INTS8 0.27 0.26 lasso 3 0.24 1.9e-08 6.0 5.9 4.5e-09 0.56 0.96 0.01 FALSE
7 GTEx Cells Transformed fibroblasts NDUFAF6 0.07 0.03 enet 9 0.01 7.6e-02 8.3 -9.6 8.4e-22 -0.69 0.06 0.88 TRUE
8 GTEx Heart Atrial Appendage NDUFAF6 0.17 0.03 lasso 6 0.04 6.7e-03 -7.3 -9.2 2.4e-20 -0.63 0.10 0.49 FALSE
9 GTEx Heart Atrial Appendage CCNE2 0.13 0.15 lasso 4 0.15 4.2e-07 7.4 -7.6 2.8e-14 -0.48 0.46 0.30 FALSE
10 GTEx Heart Left Ventricle NDUFAF6 0.10 0.05 lasso 11 0.07 1.6e-04 7.4 -8.5 1.4e-17 -0.78 0.22 0.69 FALSE
11 GTEx Ovary NDUFAF6 0.24 0.12 enet 9 0.12 6.7e-04 4.1 -5.8 6.7e-09 -0.16 0.08 0.82 FALSE
12 GTEx Skin Sun Exposed Lower leg TP53INP1 0.09 0.06 enet 13 0.07 3.3e-06 8.3 -7.5 7.9e-14 -0.32 0.03 0.97 FALSE
13 GTEx Testis TP53INP1 0.12 0.10 enet 13 0.04 6.1e-03 7.4 -7.5 4.4e-14 -0.40 0.04 0.94 FALSE
14 GTEx Testis CCNE2 0.15 0.09 lasso 4 0.10 3.5e-05 7.3 5.3 1.4e-07 0.27 0.41 0.48 FALSE
15 GTEx Whole Blood TP53INP1 0.07 0.04 enet 13 0.02 2.9e-03 8.3 7.2 4.7e-13 0.35 0.04 0.96 FALSE
16 YFS Blood TP53INP1 0.03 0.02 lasso 5 0.02 8.0e-07 7.2 7.6 3.4e-14 0.45 0.13 0.87 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma C8orf38 0.02 0.00 blup 127 0.01 4.0e-04 8.4 -8.7 4.5e-18 -0.80 0.03 0.85 FALSE
18 The Cancer Genome Atlas Colon Adenocarcinoma C8orf38 0.10 0.03 enet 20 0.06 2.0e-04 7.4 -6.0 1.8e-09 -0.58 0.07 0.42 FALSE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C8orf38 0.07 0.04 lasso 8 0.04 5.1e-05 7.4 -8.3 1.3e-16 -0.88 0.03 0.97 FALSE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TP53INP1 0.04 0.05 blup 56 0.06 4.2e-07 8.3 8.6 1.2e-17 0.57 0.01 0.99 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C8orf38 0.06 0.04 lasso 1 0.04 7.0e-05 5.2 -5.2 2.3e-07 -0.41 0.18 0.25 FALSE
22 The Cancer Genome Atlas Lung Adenocarcinoma C8orf38 0.03 0.02 blup 127 0.02 1.6e-03 5.2 -7.9 3.2e-15 -0.69 0.06 0.62 FALSE
23 The Cancer Genome Atlas Prostate Adenocarcinoma C8orf38 0.11 0.12 lasso 4 0.11 1.8e-11 8.7 -9.5 1.9e-21 -0.98 0.00 1.00 FALSE
24 The Cancer Genome Atlas Stomach Adenocarcinoma TP53INP1 0.06 0.02 lasso 3 0.03 2.8e-03 8.3 8.3 7.6e-17 0.43 0.01 0.97 FALSE
25 The Cancer Genome Atlas Thyroid Carcinoma C8orf38 0.12 0.04 lasso 3 0.08 8.3e-08 7.4 -6.1 9.2e-10 -0.70 0.31 0.67 FALSE