Best TWAS P=3.2e-09 · Best GWAS P=6.25e-08 conditioned to 0.405
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | EIF2S2P3 | 0.32 | 0.04 | enet | 15 | 0.11 | 1.2e-03 | -4.3 | -5.2 | 1.7e-07 | -0.76 | 0.02 | 0.69 | FALSE |
| 2 | GTEx | Testis | HHEX | 0.11 | 0.02 | enet | 8 | 0.00 | 4.2e-01 | -5.0 | -5.4 | 8.0e-08 | -0.86 | 0.01 | 0.85 | FALSE |
| 3 | NTR | Blood | KIF11 | 0.11 | 0.10 | lasso | 8 | 0.10 | 3.0e-29 | 5.0 | -5.2 | 1.7e-07 | -0.91 | 0.03 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | HHEX | 0.03 | 0.00 | blup | 28 | 0.02 | 1.4e-03 | -5.0 | -5.9 | 3.2e-09 | -0.84 | 0.00 | 0.49 | TRUE |