Best TWAS P=2.46e-09 · Best GWAS P=9.98e-121 conditioned to 6.69e-119
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | TSPAN9 | 0.33 | 0.06 | enet | 17 | 0.10 | 3.5e-08 | -5.85 | 6.0 | 2.5e-09 | 0.05 | 0.01 | 0.99 | TRUE |
| 2 | METSIM | Adipose | CCND2 | 0.06 | 0.03 | enet | 14 | 0.02 | 1.5e-04 | -0.99 | -5.2 | 2.3e-07 | 0.16 | 0.19 | 0.04 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | AC007618.3 | 0.06 | 0.01 | blup | 525 | 0.02 | 8.4e-04 | -5.94 | -5.7 | 9.6e-09 | 0.02 | 0.17 | 0.02 | FALSE |