TWAS
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Traits
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Traits
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Blood Red Count
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chr12:2,074,022-5,113,893
Best TWAS P=2.46e-09 · Best GWAS P=9.98e-121 conditioned to 6.69e-119
2M
2.5M
3M
3.5M
4M
4.5M
5M
0
20
40
60
80
100
120
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Thyroid
TSPAN9
0.33
0.06
enet
17
0.10
3.5e-08
-5.85
6.0
2.5e-09
0.05
0.01
0.99
TRUE
2
METSIM
Adipose
CCND2
0.06
0.03
enet
14
0.02
1.5e-04
-0.99
-5.2
2.3e-07
0.16
0.19
0.04
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
AC007618.3
0.06
0.01
blup
525
0.02
8.4e-04
-5.94
-5.7
9.6e-09
0.02
0.17
0.02
FALSE