Best TWAS P=3.68e-08 · Best GWAS P=2.58e-09 conditioned to 0.0223
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | ZNF384 | 0.08 | 0.04 | lasso | 4 | 0.04 | 2.8e-04 | 4.7 | -5.4 | 8.4e-08 | -0.57 | 0.20 | 0.58 | FALSE |
| 2 | GTEx | Nerve Tibial | MLF2 | 0.20 | 0.04 | enet | 6 | 0.04 | 1.0e-03 | 4.7 | -5.2 | 2.3e-07 | -0.26 | 0.20 | 0.23 | TRUE |
| 3 | GTEx | Nerve Tibial | ZNF384 | 0.11 | 0.02 | enet | 24 | 0.04 | 7.4e-04 | -3.2 | -5.4 | 8.2e-08 | -0.37 | 0.12 | 0.73 | FALSE |
| 4 | GTEx | Stomach | ZNF384 | 0.14 | 0.00 | enet | 21 | 0.07 | 3.1e-04 | -5.2 | -5.4 | 6.7e-08 | -0.20 | 0.06 | 0.24 | FALSE |
| 5 | NTR | Blood | NCAPD2 | 0.05 | 0.04 | lasso | 7 | 0.06 | 3.9e-20 | -5.2 | -5.5 | 3.7e-08 | -0.49 | 0.12 | 0.88 | TRUE |
| 6 | The Cancer Genome Atlas | Colon Adenocarcinoma | LPAR5 | 0.05 | 0.03 | blup | 32 | 0.03 | 1.3e-02 | 4.7 | 5.2 | 2.6e-07 | 0.60 | 0.02 | 0.52 | FALSE |
| 7 | The Cancer Genome Atlas | Rectum Adenocarcinoma | GAPDH | 0.46 | 0.13 | blup | 45 | 0.16 | 1.3e-04 | 2.5 | -5.4 | 5.8e-08 | -0.69 | 0.03 | 0.07 | FALSE |