TWAS hub - TSPAN9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2340	0.0600	5.1e-04	0.047	NA	0.109	NA	0.036	9.7e-05	NA	3.3e-09	NA	6.4e-04
2	GTEx	Adrenal Gland	0.5361	0.0746	2.1e-07	0.429	NA	0.455	NA	0.328	7.1e-17	NA	4.0e-18	NA	1.7e-12
3	GTEx	Artery Aorta	0.2520	0.0570	4.9e-05	0.257	NA	0.313	NA	0.333	2.0e-14	NA	9.8e-18	NA	5.3e-19
4	GTEx	Artery Tibial	0.1235	0.0470	8.3e-03	-0.003	NA	0.042	NA	0.000	8.5e-01	NA	2.9e-04	NA	3.4e-01
5	GTEx	Cells Transformed fibroblasts	0.3150	0.0580	1.0e-06	0.208	NA	0.265	NA	0.248	1.5e-15	NA	6.1e-20	NA	1.3e-18
6	GTEx	Esophagus Mucosa	0.1890	0.0610	3.8e-03	0.016	NA	0.087	NA	0.038	2.7e-02	NA	1.9e-06	NA	1.3e-03
7	GTEx	Esophagus Muscularis	0.1850	0.0670	8.1e-03	0.023	NA	0.014	NA	0.036	1.5e-02	NA	4.2e-02	NA	3.1e-03
8	GTEx	Nerve Tibial	0.6526	0.0470	0.0e+00	0.174	NA	0.399	NA	0.377	2.3e-12	NA	4.9e-30	NA	5.2e-28
9	GTEx	Spleen	0.6830	0.1240	5.8e-04	0.017	NA	-0.005	NA	0.009	1.2e-01	NA	4.4e-01	NA	1.8e-01
10	GTEx	Thyroid	0.3280	0.0620	4.5e-07	0.060	NA	0.102	NA	0.100	2.1e-05	NA	3.5e-08	NA	4.8e-08
11	GTEx	Vagina	0.7400	0.1440	9.8e-04	0.002	NA	0.013	NA	0.012	2.9e-01	NA	1.6e-01	NA	1.7e-01
12	TCGA	Head and Neck Squamous Cell Carcinoma	0.0631	0.0259	4.7e-03	0.008	0.028	0.009	NA	0.015	4.3e-02	4.1e-04	3.0e-02	NA	7.2e-03
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0630	0.0267	8.0e-03	0.005	0.012	0.014	NA	0.021	7.6e-02	1.4e-02	1.0e-02	NA	1.6e-03
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1300	0.0490	2.4e-03	0.043	0.012	0.002	NA	0.018	1.6e-03	6.5e-02	2.4e-01	NA	3.3e-02
15	TCGA	Lung Adenocarcinoma	0.1170	0.0333	4.8e-06	0.051	0.051	0.056	NA	0.055	1.4e-06	1.1e-06	3.5e-07	NA	5.3e-07
16	TCGA	Lung Squamous Cell Carcinoma	0.0557	0.0257	7.9e-03	-0.001	0.014	-0.002	NA	-0.001	4.7e-01	8.2e-03	8.4e-01	NA	5.2e-01
17	TCGA	Thyroid Carcinoma	0.3580	0.0510	0.0e+00	0.273	0.282	0.312	NA	0.289	1.3e-26	1.3e-27	7.5e-31	NA	2.7e-28

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Illnesses of mother	4.7	5.8	16.0	-2.9	-4.0	-3.9	-2.3	-0.7	-1.2	1.4	2.3	-1.7	-4.0	-0.2	-1.8	-1.6	-3.1	-0.9	-2.0	-2.4
Heel T-Score	3.4	27.0	55.2	-4.6	-7.0	-7.2	-2.9	-1.8	1.7	6.8	7.4	-4.7	-4.6	3.8	-2.2	-4.5	-5.9	-4.8	-5.6	-7.0
Osteoporosis (self-reported)	3.4	4.2	8.3	2.4	2.1	2.4	2.9	1.8	-0.4	-1.4	-2.0	0.7	2.8	-1.0	1.6	-0.1	2.7	2.6	1.8	2.8
HbA1C	2.9	3.2	17.9	1.2	-1.3	0.4	1.4	-1.4	1.3	2.9	3.2	0.7	-0.5	0.8	-1.1	-4.2	-1.6	-0.1	-1.1	-1.7
Crohns Disease (2017)	2.5	5.5	15.3	3.9	2.5	3.2	2.6	2.3	1.9	-0.6	-0.4	1.9	3.1	-0.1	3.3	0.8	1.9	1.1	3.2	2.4
Osteoarthritis (self-reported)	2.5	3.2	9.2	-3.0	-1.6	-2.5	-2.5	-1.3	-2.2	-1.5	0.1	-1.2	-2.8	-1.7	-1.8	0.3	-1.4	-0.5	-1.4	-1.0
Headache pain in last month	2.4	4.1	7.5	1.8	2.3	2.5	0.1	2.0	0.9	-1.2	-2.0	1.8	2.7	-1.5	2.1	2.6	2.7	1.2	2.7	2.0
High blood pressure (mother)	2.3	3.2	9.2	2.2	2.9	3.0	1.2	0.8	1.1	-1.1	-1.2	2.4	2.4	-1.0	1.7	1.3	2.1	1.1	0.6	1.7
Crohns Disease (2012)	2.2	3.5	9.7	2.8	1.8	2.3	2.3	1.8	2.1	0.0	-0.2	1.5	2.7	-0.3	3.1	0.2	1.7	0.6	2.0	1.7
Chronic bronchitis/emphysema (father)	2.2	2.6	8.4	1.1	2.2	1.5	0.6	0.4	-0.1	-0.8	-1.9	1.2	2.9	0.7	0.9	0.1	2.9	0.8	2.3	2.2
Number of full sisters	2.2	2.7	6.7	-2.5	-2.2	-2.5	-2.6	-2.2	-1.7	0.1	-0.5	-1.3	-1.9	-0.1	-1.8	-0.5	-0.9	-1.7	-0.6	-1.1
Fasting Glucose	2.1	2.5	9.5	-2.1	-1.1	-2.1	-1.8	-0.5	-0.5	-2.4	-1.2	-0.3	-1.7	-1.4	-0.1	0.3	1.2	3.1	-0.8	1.9
Ever had hysterectomy (womb removed)	2.1	2.3	7.0	0.9	1.8	1.4	-0.7	-0.8	-1.7	-2.2	-2.6	1.5	1.0	-2.1	-0.5	1.5	1.1	0.4	2.0	1.3
Blood clot in the leg (DVT)	2.1	2.7	8.1	0.7	1.7	1.5	2.7	0.2	-0.4	-2.3	-1.7	1.5	0.4	0.1	0.8	-0.0	2.3	2.8	0.2	2.8
Seen a psychiatrist for nerves, anxiety, tension or depression	2.1	2.8	9.0	-1.8	-1.0	-1.6	-1.2	-2.5	-0.5	1.2	1.3	-0.6	-1.3	-1.6	-3.0	-0.6	-1.8	-1.8	-2.2	-2.0
Pack years of smoking	2.1	3.0	13.5	2.5	1.5	1.6	3.7	2.4	1.4	0.9	0.5	0.6	2.9	0.5	1.2	0.8	1.4	1.1	1.3	1.3
Ever used hormone-replacement therapy (HRT)	1.9	2.5	6.5	0.6	2.4	2.0	0.2	-1.0	-0.1	-1.9	-2.5	2.3	1.5	-0.7	-0.5	0.7	2.1	0.5	1.6	1.9
Ever had prostate specific antigen (PSA) test	1.9	2.2	8.0	-1.3	-2.4	-2.2	-0.7	-0.9	0.6	0.9	1.1	-1.5	-1.2	-1.3	-2.2	-2.8	-1.1	-0.8	-0.3	-0.5
Pack years adult smoking proportion	1.8	2.7	11.5	2.2	1.4	1.4	3.4	2.1	1.1	0.5	0.2	0.3	2.8	0.7	1.4	0.9	1.8	1.5	1.2	1.6
Breastfed as a baby	1.8	2.2	9.8	3.1	1.2	2.0	1.5	1.7	2.1	0.7	0.3	1.3	2.4	-0.2	1.9	0.1	0.4	-0.1	1.0	0.6
Shortness of breath walking on level ground	1.8	2.2	7.7	1.3	1.0	1.6	1.1	2.6	0.6	0.3	0.0	1.5	2.4	0.7	1.8	0.2	1.4	0.6	2.8	1.3
Handedness (chirality/laterality): Left-handed	1.8	2.1	8.6	2.9	1.7	1.8	2.2	0.3	1.9	1.2	1.2	0.6	1.7	-0.6	1.3	-2.0	0.0	0.7	0.4	0.4
Commuting to job workplace: Walk	1.8	2.0	5.9	-0.2	1.6	0.9	-1.3	-1.4	-1.7	-0.8	-2.0	2.4	1.0	-1.2	-1.9	1.9	1.2	-1.1	1.1	-0.1
Medication for cholesterol	1.7	2.5	9.7	-0.2	-1.7	-1.7	0.0	0.3	1.4	2.5	2.2	-1.7	-0.5	0.7	1.5	-0.6	-1.6	-0.7	-3.1	-2.3
Deep venous thrombosis (DVT) (self-reported)	1.7	2.2	7.3	0.4	1.4	1.3	2.4	0.1	-0.6	-2.3	-1.4	1.0	0.0	0.3	0.8	0.3	2.0	2.7	0.2	2.7
Neuroticism (2016)	1.6	2.3	6.1	1.2	1.5	1.7	1.7	1.6	1.0	-0.7	-1.2	0.5	1.8	0.4	2.1	-0.6	2.5	2.4	1.0	2.0
Lung FVC	1.6	8.1	28.6	-0.3	-5.3	-5.0	1.4	0.3	2.9	2.0	4.6	-2.1	-3.5	0.5	-0.4	-0.6	-4.2	-1.9	-1.7	-2.7
Medication: Ibuprofen	1.6	2.0	4.1	2.0	1.9	2.0	1.9	1.3	0.9	-1.4	-1.1	2.0	1.4	-0.3	1.6	0.7	0.8	0.4	1.0	1.3
Irritable Bowel Disease (IBD)	1.5	3.5	13.2	3.6	1.7	2.4	1.0	1.5	1.4	0.4	0.7	2.0	2.8	0.8	2.9	0.5	1.2	0.5	2.3	1.6
Major Depression (MDD)	1.5	1.8	5.6	1.3	2.1	2.4	0.6	-0.0	0.2	-0.7	-1.4	1.5	1.2	0.8	1.5	1.5	1.5	1.2	1.7	1.0
Bilateral oophorectomy (both ovaries removed)	1.5	1.7	4.1	0.9	2.0	1.8	0.0	0.0	-0.0	-1.5	-1.5	0.7	1.9	-0.6	-0.2	1.3	1.5	0.6	2.0	1.7
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.8	5.1	1.9	1.7	1.6	1.9	1.1	1.2	-1.0	-1.0	2.3	1.4	0.5	2.1	0.6	0.6	0.7	0.4	1.0
Chronic bronchitis/emphysema (mother)	1.5	1.7	9.6	2.2	1.9	2.1	0.6	0.7	0.0	0.3	-1.1	0.8	3.1	1.4	-0.0	0.6	0.5	0.1	0.9	1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.1	6.8	-2.2	-2.0	-2.5	-1.5	-1.9	-0.8	1.8	1.7	-2.6	-1.6	1.5	-1.3	-0.7	-1.6	-1.3	-1.7	-2.1
Qualifications: CSEs or equivalent	1.4	1.8	7.2	-1.3	0.8	0.1	-0.1	-1.5	-2.7	-2.3	-1.3	-0.0	-0.6	-1.2	-1.5	1.0	1.6	1.7	-0.1	1.3
Stomach or abdominal pain in last month	1.4	1.7	6.7	0.2	1.9	0.9	0.0	-0.1	0.5	-1.4	-0.9	0.9	1.6	-0.7	0.6	1.4	2.6	1.3	1.5	2.0
Depression (self-reported)	1.4	1.7	3.6	-0.4	-1.2	-1.5	-0.6	-1.5	-0.6	1.5	1.9	-0.5	-1.0	1.6	-1.9	-1.5	-1.5	-0.2	-1.6	-1.2
Pulse wave Arterial Stiffness index	1.4	1.6	4.5	2.1	1.4	1.4	0.1	1.9	1.2	-0.8	-0.4	1.2	1.5	0.6	1.9	0.8	0.4	1.4	0.5	1.6
Glaucoma (self-reported)	1.4	1.7	7.0	-0.0	-1.2	-0.4	-0.6	1.2	2.6	1.9	1.6	-1.3	0.0	2.0	0.4	-0.3	-1.3	-1.0	-0.1	-1.8
Pulse wave peak to peak time	1.4	1.6	4.3	-2.0	-1.2	-1.3	0.1	-2.1	-1.4	0.5	0.3	-1.3	-1.7	-0.7	-1.9	-0.4	-0.4	-1.2	-0.6	-1.6
Ever depressed for a whole week	1.4	1.7	7.5	-1.5	-1.1	-1.5	0.0	-2.7	-0.3	0.0	0.7	-1.1	-1.9	0.5	-1.6	-0.7	-0.5	-0.6	-2.2	-0.9
Angina	1.3	1.8	6.9	0.8	1.0	0.8	-1.1	-0.9	1.2	2.0	0.8	1.3	2.6	1.6	-0.7	-0.3	0.9	-1.8	1.8	-0.2
Mouth/teeth dental problems	1.3	2.0	4.9	-1.8	-0.8	-1.8	-2.2	-2.2	-2.2	-1.0	-0.4	-0.3	-2.0	0.6	-1.2	-0.1	1.3	1.5	-0.8	0.5
Ever highly irritable/argumentative for 2 days	1.3	1.6	6.1	-1.6	-1.8	-2.5	-1.0	-1.8	-0.4	0.4	0.8	-1.0	-0.8	0.6	-1.5	-0.6	-0.9	-0.7	-1.2	-1.4
Neck or shoulder pain in last month	1.3	1.8	8.3	-1.8	-0.1	-1.1	-1.2	-2.9	-1.9	0.0	-1.1	1.0	-0.4	0.5	-2.3	0.7	-0.2	-1.7	-0.2	-0.8
Alcohol intake frequency.	1.3	3.0	7.8	0.1	2.4	1.5	-0.8	-0.3	-1.2	-2.1	-2.5	1.2	1.7	-0.2	-1.4	1.3	2.4	1.3	2.8	2.5
Angina (self-reported)	1.2	1.6	7.0	0.8	0.8	0.6	-0.8	-0.7	1.2	2.0	1.0	1.1	2.6	1.4	-0.8	0.1	0.7	-2.0	1.6	-0.2
Illnesses of siblings: Diabetes	1.2	1.5	4.4	-2.0	-1.7	-2.1	-1.3	-1.6	-0.3	0.1	0.6	-1.0	-1.2	-1.2	-1.2	0.4	-0.8	-0.8	-1.1	-1.3
Loneliness, isolation	1.2	1.6	6.0	-0.9	1.7	0.8	-0.8	-2.5	-1.4	-1.0	-1.2	1.5	0.3	-0.9	-1.4	-0.3	1.3	-0.1	2.1	0.5
Eye problems/disorders: Glaucoma	1.2	1.4	5.7	0.9	-0.9	0.3	0.2	1.3	2.4	1.2	1.1	-0.6	-0.4	2.3	0.6	0.6	-1.6	-0.8	0.1	-1.5
Medication: Atorvastatin	1.2	1.5	7.2	-0.1	1.8	0.2	-0.9	-1.6	-0.8	-1.3	-0.9	0.1	1.4	-0.0	0.5	0.4	2.7	1.0	0.7	2.1
Sensitivity / hurt feelings	1.1	1.8	12.9	-1.8	-0.3	-0.9	-1.1	-3.6	-1.1	0.0	0.1	1.4	-1.2	0.3	-1.1	-0.4	-0.0	-1.7	-1.4	-1.3
Trunk fat percentage	1.1	4.4	15.2	1.5	3.5	3.0	0.0	0.2	-1.4	-0.2	-2.4	1.8	3.9	-0.1	-0.4	0.9	2.8	1.7	2.9	2.1
Loud music exposure frequency	1.1	1.2	4.3	-0.4	0.3	0.2	0.2	-0.0	-1.5	-1.7	-1.4	-0.7	0.7	-1.5	-0.7	-0.9	2.1	1.1	0.0	1.8
Medication: Ventolin 100micrograms inhaler	1.1	1.4	3.8	-1.5	-1.4	-1.3	-1.9	-0.7	-0.3	-0.2	0.8	-2.0	-1.8	-1.5	-1.1	0.7	-0.7	-1.0	-0.8	-0.6
Forced vital capacity (FVC), Best measure	1.1	4.1	11.5	0.8	-2.8	-2.1	2.9	1.2	2.5	1.2	3.4	-1.3	-2.9	-0.1	1.6	-0.5	-2.7	-0.3	-2.2	-1.7
Body fat percentage	1.1	4.2	15.4	1.4	3.3	2.8	-0.3	-0.0	-1.8	-0.1	-2.4	1.8	3.9	-0.0	-0.8	0.8	2.6	1.4	3.0	2.0
Commuting to job workplace: Public transport	1.1	1.3	7.2	1.7	1.6	1.7	-0.7	0.7	0.8	-0.4	-0.5	0.4	0.9	0.2	2.7	0.9	0.7	1.4	0.8	0.5
Medication: Blood pressure	1.1	2.1	5.2	1.1	2.3	2.3	-0.1	0.3	-0.8	-2.0	-1.9	1.0	1.2	-1.8	-0.6	1.5	1.3	1.0	1.5	1.7
Leg fat percentage (left)	1.1	3.9	16.2	0.8	3.0	2.5	-0.7	-0.4	-2.0	-0.1	-2.6	1.8	4.0	-0.4	-1.4	0.7	2.4	0.4	3.2	1.5
Lupus	1.0	1.6	7.1	0.3	0.7	1.0	1.0	1.8	-0.3	-1.5	-1.5	1.2	0.8	-1.1	0.9	2.7	0.9	1.3	0.6	1.5
Chronotype (morning person)	1.0	2.2	6.9	-1.6	-0.8	-2.0	-1.5	-1.4	-1.0	-0.7	0.1	-2.3	-2.0	0.6	-2.6	2.2	-1.5	-0.7	0.3	-1.0
High blood pressure	1.0	2.7	7.2	1.1	2.3	1.6	-0.3	-0.9	-0.1	-2.0	-2.3	1.5	1.8	-1.9	-0.4	2.7	2.1	0.4	1.0	1.9
Impedance of leg (left)	1.0	4.8	15.9	0.0	3.1	2.4	-1.4	-1.1	-3.6	1.9	-1.5	2.6	4.0	0.6	-1.2	0.9	1.7	-2.4	3.0	-1.2
Forced vital capacity (FVC)	1.0	3.7	10.0	0.7	-2.9	-2.0	2.6	0.5	2.1	0.8	3.2	-1.8	-3.0	0.2	1.5	-0.7	-2.4	0.1	-2.4	-1.2
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	4.3	0.4	2.1	1.1	-0.9	0.1	-1.2	-1.6	-1.4	0.7	1.4	-0.6	-0.8	1.9	0.9	-0.1	0.6	0.9
Time employed in main current job	1.0	1.1	2.5	0.2	-0.8	-1.0	-1.5	-0.8	1.2	1.4	1.6	-1.0	-0.4	1.3	-0.9	-0.3	-1.4	-0.9	-0.3	-1.4
Number of live births	1.0	1.4	4.6	-0.4	-1.9	-1.8	0.1	-1.2	0.7	0.8	0.4	-0.8	-0.8	-1.0	-1.7	-2.1	-0.1	-0.9	-1.4	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	8.5	1.0	-2.2	-1.5	2.5	1.3	2.1	1.2	2.9	-0.3	-1.9	-0.0	1.7	1.1	-2.6	-0.8	-1.8	-1.9
Exposure to tobacco smoke at home	1.0	1.2	5.9	-1.7	-1.0	-2.0	-0.9	-1.3	-0.8	0.7	0.1	-0.0	-0.3	2.4	-1.2	-0.3	-0.3	-0.9	0.1	-0.5
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	5.2	0.7	0.3	1.1	2.3	1.2	1.7	1.0	0.4	0.3	1.6	0.6	1.5	0.2	-1.0	-1.4	0.9	-0.9
Leg fat percentage (right)	1.0	3.8	17.2	1.0	2.7	2.3	-0.5	-0.1	-1.7	0.1	-2.1	1.5	4.1	0.1	-1.0	1.1	2.4	0.5	3.5	1.6
Eye problems/disorders: None of the above	1.0	1.1	3.1	0.2	1.3	0.5	0.1	0.2	-1.4	-1.2	-1.8	0.5	0.8	-1.6	0.3	-1.2	1.6	0.8	0.0	1.6
Commuting to job workplace: Car/motor vehicle	1.0	1.1	3.1	-0.6	-0.9	-1.1	1.1	-1.0	0.7	1.1	1.8	-0.3	-1.0	1.3	-1.0	-0.7	-1.1	-1.3	-1.4	-0.9
Supplements: Vitamin C	1.0	1.1	5.2	0.7	0.6	0.8	0.7	-0.2	2.3	0.3	-0.6	1.3	0.9	2.1	-0.3	-1.6	0.8	0.6	0.0	0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	8.9	-0.2	-0.1	0.3	1.0	0.1	-0.2	-3.0	-0.2	-0.7	-1.8	-2.4	1.2	0.7	1.0	3.0	-0.6	1.8
Mineral and other dietary supplements	1.0	1.3	3.8	-0.6	-1.3	-1.1	-0.6	-0.8	0.9	1.4	1.0	-1.6	-1.3	0.4	-0.3	-0.0	-1.9	-1.6	0.2	-1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.0	5.7	1.0	-2.2	-1.1	1.4	1.4	2.4	1.1	2.2	-0.2	-0.7	-0.6	1.0	0.7	-2.4	-0.8	-0.8	-1.5
Medication: Bendroflumethiazide	1.0	1.5	7.4	0.8	1.0	0.7	0.6	1.1	-0.8	-1.9	-1.0	0.3	0.6	-2.7	0.6	1.0	0.6	1.9	0.2	1.7
Average weekly spirits intake	0.9	1.1	5.3	-0.4	0.4	-0.3	-0.9	-0.9	-1.0	0.7	0.0	0.1	0.7	0.8	-1.9	1.6	-0.7	-2.3	0.1	-1.3
Vitamin and mineral supplements	0.9	1.2	3.3	-1.0	0.1	-1.1	-1.2	-1.1	-1.2	-0.1	0.1	-1.7	-0.7	-0.7	-1.3	1.8	-1.3	-1.6	-0.2	-1.2
Severe depression (siblings)	0.9	1.0	5.2	-0.5	-0.3	-0.8	-2.3	-0.8	0.6	1.2	1.1	-1.3	-0.3	0.3	0.3	1.4	-0.6	-0.7	0.7	-1.6
Townsend deprivation index at recruitment	0.9	1.2	4.3	-1.3	0.8	0.1	-0.2	-0.8	-1.2	-2.1	-1.7	1.4	0.1	0.0	0.0	-0.9	1.6	1.0	0.2	1.7
Illnesses of siblings	0.9	1.3	3.0	1.6	1.0	1.6	0.6	0.8	-0.1	-0.7	-0.9	1.1	-0.1	0.9	1.3	-0.5	1.3	1.6	1.4	1.7
Hip circumference	0.9	3.9	9.4	1.8	2.4	2.6	1.5	1.2	-0.6	-2.4	-2.6	0.7	2.2	-1.8	-0.1	1.1	2.4	2.3	1.9	3.1
Father’s age at death	0.9	1.3	4.0	0.2	-1.1	-0.1	0.8	0.7	0.5	1.4	1.5	-0.2	-0.5	0.5	0.6	-1.6	-1.8	-2.0	1.2	-1.5
Hair/balding pattern: Pattern 3	0.9	1.3	7.5	1.6	-0.1	-0.2	0.4	1.3	2.7	-0.0	0.3	-0.6	1.1	-0.9	2.1	1.6	0.2	0.2	-0.8	0.6
Mouth/teeth dental problems: Loose teeth	0.9	1.1	5.0	0.7	0.1	0.1	2.2	1.2	1.9	-0.4	-0.4	0.4	1.2	0.8	0.8	-0.2	1.2	-0.3	1.3	1.1
Migraine (self-reported)	0.9	1.1	4.2	1.3	1.3	0.8	0.7	1.2	0.3	0.5	-0.4	1.4	2.1	0.1	0.2	1.8	0.6	0.5	1.4	0.2
Heart disease (mother)	0.9	1.0	5.7	1.8	1.2	1.2	1.0	-0.1	0.2	0.6	0.6	0.3	2.4	1.1	1.0	0.1	1.1	0.2	0.7	0.5
Hypertension (Self-reported)	0.9	2.5	5.5	1.2	2.3	1.5	-0.3	-1.3	-0.1	-1.7	-1.8	1.8	1.7	-2.2	-0.6	2.3	2.0	0.4	0.8	1.9
Illnesses of father: Heart disease	0.9	1.2	4.4	0.9	1.3	0.8	1.2	-1.3	-1.6	0.1	0.3	1.5	0.8	-1.7	-2.1	-0.5	0.5	-0.9	-0.1	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	3.3	-0.4	-0.7	-0.9	-1.0	-0.4	0.8	1.3	1.4	-1.3	-0.7	1.8	-1.1	-1.0	-1.1	-0.3	-0.8	-0.8
Bipolar Disorder or Schizophrenia	0.8	1.8	4.9	-1.5	-1.9	-1.9	-2.2	-1.4	-0.6	0.7	1.2	-0.5	-0.9	-1.4	-1.6	1.1	-1.2	-1.2	0.5	-1.8
Schizophrenia (2018)	0.8	1.7	5.4	-1.8	-1.7	-1.6	-1.4	-1.9	-1.4	0.1	0.7	-0.0	-0.6	-1.1	-2.3	0.5	-1.0	-1.4	0.5	-1.3
Ulcerative Colitis (UC)	0.8	1.6	6.2	2.5	1.0	1.5	0.2	0.6	0.7	0.8	1.0	1.8	1.9	1.5	2.0	0.2	0.7	0.5	0.8	0.9
Ovarian Cancer	0.8	1.1	5.4	-0.9	-0.3	-0.6	-1.1	-0.6	-2.3	-1.6	-0.9	-0.5	-1.8	-1.3	-0.0	1.0	-0.5	0.9	0.0	-0.2
LDL Cholesterol	0.8	1.3	3.5	0.5	-0.4	-0.1	0.4	-0.6	0.4	1.8	1.6	1.8	0.1	1.9	0.4	-1.1	-1.1	-0.9	-1.6	-1.6
Primary Biliary Cirrhosis	0.8	1.1	3.5	1.7	0.7	1.0	0.5	1.0	0.8	0.7	-0.6	1.9	1.4	0.6	1.1	-0.5	0.7	1.0	1.5	0.8
Ulcerative Colitis	0.8	1.2	3.8	1.5	0.7	0.9	0.3	1.1	0.9	0.5	0.3	2.0	1.5	0.4	1.9	0.1	1.0	0.4	1.5	1.0
Waist Hip Ratio (WHR)	0.8	3.7	21.6	-1.6	-0.7	-1.9	-1.6	-4.7	-2.9	1.5	0.8	1.5	-0.4	-0.1	-3.4	-1.2	-0.7	-1.7	-0.2	-1.2
Lung FEV1/FVC ratio	0.8	4.2	18.7	2.2	-0.0	0.9	1.6	2.8	2.6	1.9	0.8	1.9	3.0	0.3	1.9	4.3	-1.4	-2.1	1.1	-1.6
Medication for hormone replacement therapy	0.8	0.9	4.6	0.7	-0.1	0.2	0.6	0.6	0.9	-0.1	0.1	0.9	-0.3	0.6	0.6	-1.5	1.1	0.8	2.1	1.6
Medication: Metformin	0.8	1.1	5.1	-0.0	1.1	0.5	-0.1	-1.8	-2.3	-0.1	-1.4	0.9	0.8	0.1	-1.7	0.2	0.1	-1.1	1.1	-0.1
Impedance of leg (right)	0.8	4.0	15.1	0.3	2.6	2.1	-1.2	-0.7	-3.1	2.2	-0.9	1.9	3.9	1.0	-0.8	1.1	1.6	-2.0	3.2	-1.1
Average weekly fortified wine intake	0.8	0.9	3.8	1.2	0.1	0.2	1.4	1.7	0.1	-0.6	-0.2	-0.1	0.1	-1.9	1.4	-0.0	0.6	1.1	0.8	0.9
Age when periods started (menarche)	0.8	2.0	6.1	-1.4	-2.5	-2.3	-0.7	-0.9	-0.2	0.5	0.8	-1.1	-2.4	0.3	-1.1	-1.7	-2.1	-0.5	-0.7	-1.1
Multivitamins +/- minerals	0.8	1.0	3.4	0.2	-0.1	0.7	1.1	0.2	-0.2	-0.6	-0.7	1.5	0.3	-0.7	0.7	-1.7	1.6	1.8	0.0	1.4
Qualifications: None of the above	0.8	1.8	5.1	-1.6	-1.6	-1.7	-1.6	-0.2	1.0	1.2	1.0	-1.2	0.1	1.8	-1.5	-0.1	-1.3	-2.2	1.1	-1.3
Noisy workplace	0.8	0.9	3.4	0.4	0.1	0.6	1.9	1.8	0.5	0.1	-0.0	1.4	0.9	-1.3	1.2	0.7	0.2	0.4	1.2	0.7
Pulse wave reflection index	0.8	1.0	2.9	0.7	-0.4	-0.1	-0.3	1.2	1.7	0.1	0.4	-0.5	0.6	1.3	1.5	-1.1	1.1	1.7	0.5	1.5
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	4.7	-0.5	-1.2	-1.2	-0.9	-0.7	0.1	1.4	0.7	0.1	-0.8	0.8	-1.2	-1.6	-2.2	-1.9	-1.6	-1.6
Comparative body size at age 10	0.8	2.3	7.5	1.6	1.4	1.3	1.4	1.2	1.5	-2.2	-0.7	-0.1	1.5	-1.0	2.0	0.8	1.9	1.9	0.0	2.7
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	3.4	-0.7	-1.3	-1.1	-0.2	0.1	-0.1	0.0	-0.2	-1.2	-1.8	-1.2	0.2	-0.8	-0.9	-0.2	-1.8	-0.7
Medication: Omeprazole	0.8	0.9	2.9	0.2	-1.0	-0.8	0.4	0.3	1.7	1.6	1.7	-1.0	-0.1	0.3	1.1	-0.5	-1.0	-0.2	-1.2	-0.9
Suffer from ‘nerves’	0.8	1.3	7.8	1.1	-0.4	-0.4	1.8	0.3	0.7	2.3	2.8	1.3	0.5	-0.6	0.8	-0.9	-0.1	-0.3	-0.1	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	6.6	-0.6	0.2	-0.1	0.2	-2.6	-0.2	-0.0	-0.1	1.4	-0.0	-1.4	-1.3	0.2	-0.2	-0.3	-1.3	-0.7
Medication: Gliclazide	0.8	0.9	5.2	0.7	0.2	0.2	-1.9	-0.5	-0.4	1.0	-0.6	1.1	1.2	-0.7	-0.4	0.2	0.5	-0.4	2.3	-0.2
Age started oral contraceptive pill	0.8	0.9	4.8	-0.8	0.3	0.5	-0.5	-1.0	-1.3	-1.0	-0.8	-0.4	-0.6	-2.2	-1.5	-0.0	-0.2	-0.3	-1.5	-0.5
Diastolic blood pressure, automated reading	0.8	2.6	7.3	2.1	2.4	2.7	-0.1	1.1	1.2	-1.2	-0.6	1.7	1.8	0.1	1.1	-0.1	2.0	2.2	1.6	2.1
Vascular/heart problems diagnosed by doctor	0.8	2.2	5.3	-1.1	-2.3	-1.6	0.5	1.3	-0.2	1.5	2.0	-1.8	-1.8	1.3	0.5	-1.9	-1.8	-0.0	-1.1	-1.7
Cholesterol lowering medication	0.8	1.2	3.3	-0.9	-0.2	-0.5	-1.3	-0.8	-0.6	-1.6	-1.6	-1.3	-0.1	0.3	-1.8	1.7	0.6	-0.5	1.1	1.0
Impedance of whole body	0.8	3.9	14.4	0.4	3.4	2.8	-1.1	-0.6	-2.1	2.3	-0.9	2.1	3.8	1.6	-0.6	0.6	1.6	-1.3	2.8	-1.1
Mean Putamen Volume	0.7	0.8	3.2	-0.3	0.2	0.3	-0.6	0.4	-1.7	0.3	-0.1	1.6	-0.2	-1.8	-0.8	1.0	-0.8	-0.6	0.5	-1.1
HDL Cholesterol	0.7	1.2	3.3	-0.9	0.6	0.1	0.2	-0.5	-1.5	-1.8	-1.5	-0.3	-0.4	0.6	-1.0	0.7	1.7	1.6	0.7	1.5
Blood Red Count	0.7	7.2	35.6	3.5	3.6	3.7	1.5	1.8	1.6	0.8	-0.2	2.6	6.0	-0.6	1.4	0.9	3.4	0.8	3.7	1.8
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.5	0.6	0.7	0.5	0.2	-0.8	0.9	-0.8	-0.9	1.2	0.9	-0.7	0.9	0.6	1.5	-0.1	1.6	1.5
Medication: Co-codamol	0.7	0.8	3.4	-0.2	1.2	0.1	-0.5	-1.2	0.4	-0.2	-0.7	1.2	1.5	-0.1	-1.8	-0.6	1.0	-0.9	0.3	0.6
Relative age voice broke	0.7	1.1	3.9	-0.3	-0.5	-0.5	-0.5	0.6	-0.5	-2.0	-0.7	-1.9	-0.9	0.8	1.4	1.8	0.0	1.5	0.1	0.9
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	2.1	-1.1	-1.1	-1.0	-0.8	0.5	0.4	0.7	0.0	-1.0	-0.8	0.4	1.2	-0.5	-1.3	-0.5	0.2	-1.4
Medication: Atenolol	0.7	0.9	3.2	0.9	1.6	1.4	-1.1	0.4	0.6	-0.0	-0.4	0.7	1.8	-0.9	-0.1	1.2	0.5	1.4	0.4	0.3
Trunk fat mass	0.7	2.9	6.8	1.5	2.5	2.3	0.8	0.5	-0.8	-0.9	-1.8	0.9	2.6	-0.5	0.2	0.8	2.3	2.3	1.8	2.5
Past tobacco smoking	0.7	1.2	9.0	-0.3	1.5	0.9	-1.5	0.8	-1.1	-1.3	-0.6	-0.5	-0.2	-0.7	1.0	3.0	0.3	0.9	-0.5	0.1
Had menopause	0.7	0.9	3.1	0.0	0.9	1.0	-0.5	0.2	0.0	-0.9	-1.8	1.6	1.3	-0.3	-0.2	-0.1	1.5	0.6	0.7	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	3.5	-1.4	-1.3	-1.6	-1.1	-1.5	-0.9	1.4	1.3	-1.9	-1.3	1.6	-1.2	-0.3	-1.1	-1.0	-0.8	-1.6
Heart attack	0.7	1.0	4.8	0.4	1.2	0.3	-1.3	-1.2	-0.7	0.6	-0.5	0.4	2.2	-0.0	-1.0	-0.8	1.3	-0.9	0.8	0.8
Trunk fat-free mass	0.7	4.2	10.6	0.8	-2.0	-1.2	3.1	1.1	1.4	-2.9	1.2	-2.3	-3.3	-2.1	1.8	-0.0	-0.7	2.6	-2.6	2.1
Alcohol intake versus 10 years previously	0.7	1.1	2.8	-1.0	-1.2	-1.4	-1.2	-1.1	-1.3	0.9	0.8	-0.1	-0.4	0.3	-1.7	-0.4	-0.9	-1.5	0.6	-1.0
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	6.5	0.8	-2.1	-1.3	2.1	0.4	1.9	0.5	2.5	-0.6	-2.2	-0.1	1.5	1.1	-2.3	-0.4	-2.2	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.2	0.3	1.1	1.0	1.5	-0.0	-0.8	-0.9	-0.9	0.9	0.0	-0.3	0.6	0.7	0.6	0.7	1.4	1.3
Trunk predicted mass	0.7	4.1	10.5	0.9	-2.0	-1.2	3.0	1.1	1.4	-2.9	1.1	-2.3	-3.2	-2.1	1.8	0.0	-0.7	2.6	-2.5	2.1
Medication: Amlodipine	0.7	0.9	2.9	0.3	1.1	0.8	-0.2	-1.6	-0.5	-1.2	-1.7	0.1	-0.2	-1.5	-1.1	0.5	0.9	0.7	0.5	1.2
Mean time to correctly identify matches	0.7	1.3	7.6	0.7	-1.0	-0.4	-0.7	0.8	2.8	1.8	1.2	0.5	0.1	1.3	-0.6	-0.1	-1.7	-0.7	0.4	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	5.4	-1.6	-0.5	-0.4	-0.8	1.1	-2.3	-1.1	-1.1	0.2	-0.9	-0.3	-0.4	-0.1	-0.0	0.6	-0.2	-0.1
Leg fat mass (right)	0.7	2.6	6.4	1.0	2.1	1.7	0.7	0.1	-1.2	-1.1	-1.9	0.8	2.5	-0.9	-0.3	0.8	2.4	1.8	2.1	2.5
Knee pain experienced in last month	0.7	1.0	4.4	-0.3	-0.1	-0.3	1.3	1.1	0.4	-2.1	-1.1	-0.2	-0.3	-0.7	0.5	0.1	0.7	1.7	1.1	1.8
Whole body fat-free mass	0.7	3.8	9.7	0.8	-1.3	-0.8	3.0	0.9	1.3	-3.1	0.6	-1.8	-2.8	-2.2	1.7	-0.1	-0.1	3.1	-2.2	2.6
Eye problems/disorders: Cataract	0.7	0.8	6.3	0.4	-1.0	-0.5	-0.2	-0.1	2.5	0.7	1.3	-0.4	-0.0	0.3	-0.0	1.6	-0.4	-0.7	-0.0	-0.7
Whole body water mass	0.7	3.8	9.6	0.8	-1.2	-0.8	3.0	0.9	1.3	-3.1	0.6	-1.8	-2.8	-2.1	1.6	-0.1	-0.0	3.0	-2.2	2.7
Financial situation satisfaction	0.7	0.9	6.0	0.3	0.4	1.2	0.5	0.8	-0.1	0.3	-0.6	2.5	0.4	0.2	1.3	0.4	1.1	-0.2	1.5	-0.3
Average weekly beer plus cider intake	0.7	1.1	7.7	0.6	-0.3	-0.2	0.6	1.1	2.8	0.8	0.5	-0.6	0.6	1.7	1.9	0.5	-0.3	-0.3	-0.4	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	3.2	0.7	-0.9	-0.5	0.1	0.5	1.8	1.8	1.6	-0.4	0.5	0.4	1.1	-0.3	-0.8	-0.5	-0.7	-1.1
Supplements: Calcium	0.7	0.8	2.8	0.5	0.5	1.4	1.7	0.8	0.6	-0.9	-0.7	0.7	1.2	-0.2	0.1	-0.6	1.4	1.0	0.6	0.9
Heart attack/myocardial infarction (self-reported)	0.7	1.0	3.4	0.1	0.9	-0.0	-1.7	-1.4	-0.8	1.0	-0.2	0.0	1.8	0.0	-1.4	-0.9	0.8	-1.3	0.6	0.3
Schizophrenia vs Biploar Disorder	0.6	0.7	2.4	-1.2	-0.1	-0.7	-0.0	-0.6	-1.6	-1.2	-1.1	0.2	0.0	-1.3	-0.1	0.8	0.6	1.2	-0.8	0.7
Age at First Birth	0.6	0.9	3.3	-0.1	-1.1	-0.3	0.3	1.8	0.1	-0.7	0.6	-1.6	-1.0	0.4	0.4	-1.5	-0.4	1.8	0.6	0.7
Frequency of depressed mood in last 2 weeks	0.6	0.9	4.3	-0.5	1.6	0.8	-1.4	-1.7	-0.5	-0.2	-0.2	2.1	0.1	0.4	0.2	0.4	0.9	0.3	0.8	0.2
Leg fat-free mass (left)	0.6	3.2	11.2	0.9	-0.6	-0.4	2.9	0.8	1.6	-2.7	0.4	-1.6	-2.1	-1.5	1.7	-0.1	0.5	3.3	-1.7	2.7
Leg predicted mass (left)	0.6	3.3	12.0	1.0	-0.7	-0.4	2.9	0.9	1.6	-2.6	0.5	-1.6	-2.1	-1.5	1.9	-0.2	0.5	3.5	-1.8	2.8
Pain all over the body in last month	0.6	0.7	2.2	0.1	-0.8	-0.7	-0.5	0.1	0.6	0.0	1.2	-1.5	-1.1	0.2	-0.1	0.7	-1.2	1.4	-1.1	-0.0
Impedance of arm (right)	0.6	2.8	10.5	1.3	2.7	2.6	-0.6	0.1	-0.4	2.4	-0.3	1.6	3.2	1.9	0.1	0.3	1.0	-0.8	2.4	-0.9
Pulse rate	0.6	1.1	3.5	0.4	0.6	1.2	-1.1	0.6	0.3	-1.1	-1.0	1.4	-1.2	1.1	1.4	1.9	-1.2	0.3	-0.7	-0.7
Lung cancer (father)	0.6	0.7	2.7	0.3	-0.4	0.1	1.1	1.2	1.7	-0.7	-0.4	0.1	0.6	-0.7	1.6	1.1	0.1	0.2	-0.2	0.4
Impedance of arm (left)	0.6	2.8	9.8	1.0	2.7	2.5	-0.7	0.2	-0.0	2.5	-0.1	1.4	3.1	2.6	0.2	0.5	0.8	-0.7	2.1	-1.2
Birth weight of first child	0.6	1.1	3.1	-1.5	0.2	-0.2	-0.7	-0.7	-1.8	-1.6	-1.6	-0.6	-0.6	-1.6	-1.0	1.5	0.2	-0.5	-0.2	-0.2
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	3.0	-0.1	1.0	1.4	0.2	1.4	0.3	-1.7	-1.6	-0.5	-0.2	0.6	0.7	0.7	0.7	1.2	0.9	0.9
High blood pressure (siblings)	0.6	0.8	2.8	-1.3	-0.2	-0.7	-1.6	-0.5	-0.1	0.4	0.1	-1.0	-0.5	-0.4	-0.8	1.0	-0.6	-1.0	-1.7	-1.2
Arm fat-free mass (right)	0.6	2.9	8.5	0.5	-0.7	-0.6	2.9	0.4	0.3	-2.9	0.1	-1.1	-2.1	-2.4	1.2	0.0	0.4	2.6	-2.2	2.5
Number of full brothers	0.6	0.7	2.1	0.4	-0.8	-0.2	0.1	1.2	0.5	1.5	0.3	-0.6	1.3	1.3	-1.1	0.2	0.2	-0.8	1.3	-0.2
Emphysema/chronic bronchitis	0.6	0.7	5.0	-0.3	-0.1	-0.4	0.1	0.2	-0.8	-0.7	-0.5	-1.6	-0.6	0.4	0.5	-0.3	0.6	2.2	0.3	1.2
Whole body fat mass	0.6	2.3	5.9	1.2	2.1	1.8	0.7	0.5	-1.0	-1.0	-1.8	0.7	2.2	-0.5	0.0	0.7	2.0	2.2	1.8	2.4
Family relationship satisfaction	0.6	0.7	3.3	0.1	0.9	1.0	1.8	0.5	0.2	-0.4	-0.7	1.2	-0.0	-0.0	1.2	-1.3	0.8	0.1	-0.1	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	3.3	1.0	0.0	0.1	-0.0	0.9	1.1	0.7	1.4	0.3	0.7	1.2	1.0	1.8	-0.3	0.1	-0.4	-0.4
Leg fat-free mass (right)	0.6	3.1	9.3	0.6	-0.6	-0.4	2.8	0.5	1.5	-2.9	0.3	-1.4	-2.5	-1.6	1.4	-0.4	0.2	3.0	-2.1	2.6
Arm fat percentage (left)	0.6	2.3	8.4	1.1	2.3	2.0	-0.4	0.0	-0.8	-0.2	-1.9	0.9	2.9	0.2	-0.6	0.7	1.9	1.6	2.3	1.7
Friendships satisfaction	0.6	0.8	3.7	-0.3	0.1	0.7	0.6	0.6	-0.8	-1.9	-1.0	-0.7	-1.3	-0.3	0.5	-0.1	0.4	1.4	0.4	1.3
Breast cancer (self-reported)	0.6	0.7	2.6	-0.7	-1.2	-1.3	-0.0	0.5	0.2	-0.5	0.2	-0.0	-0.9	-1.6	0.5	0.7	-1.4	0.7	-1.2	-0.4
Smoking status: Current	0.6	1.0	4.3	-0.3	-0.7	-0.2	0.4	2.1	0.8	0.9	0.3	-1.0	1.1	1.8	1.3	-0.3	0.6	-0.7	1.3	0.0
Leg predicted mass (right)	0.6	3.1	9.6	0.7	-0.6	-0.4	2.8	0.5	1.5	-2.9	0.2	-1.3	-2.5	-1.6	1.5	-0.4	0.2	3.1	-2.0	2.6
Average weekly champagne plus white wine intake	0.6	0.8	4.6	1.0	1.2	1.0	1.8	0.9	2.1	0.5	0.7	-0.5	0.4	-0.6	0.4	-0.6	-0.1	0.4	-0.1	0.2
Miserableness	0.6	1.0	4.1	-0.3	0.7	0.5	-0.2	-0.7	-1.7	-1.1	-0.8	2.0	0.2	-1.3	0.0	0.1	1.8	1.0	0.5	1.3
Ever taken oral contraceptive pill	0.6	0.7	5.7	-0.4	-0.4	-0.4	-1.0	-1.2	-2.4	-0.3	-0.5	-0.1	-0.8	-0.7	-0.4	-0.8	0.3	0.3	-0.0	0.2
Ever smoked	0.6	1.0	5.9	-0.1	-1.8	-1.5	0.8	-0.8	1.2	1.1	0.3	0.2	-0.1	0.8	-0.7	-2.4	0.1	-1.0	0.4	0.0
Basal metabolic rate	0.6	3.1	9.5	0.8	-0.8	-0.4	2.9	0.8	0.9	-2.9	0.3	-1.6	-2.2	-1.9	1.5	0.0	0.2	3.1	-1.8	2.6
Arm fat-free mass (left)	0.6	2.9	9.1	0.0	-1.3	-1.1	2.4	0.2	-0.1	-3.0	0.2	-1.6	-2.6	-2.5	0.7	-0.3	0.1	2.4	-2.0	2.3
Commuting to job workplace: Cycle	0.6	0.8	3.7	0.1	0.4	-0.3	-1.9	-0.8	0.7	-0.8	-1.8	-0.0	0.3	-1.0	-1.1	1.3	-0.2	0.0	-0.4	-0.2
Leg fat mass (left)	0.6	2.5	6.0	0.8	2.1	1.7	0.5	-0.2	-1.4	-1.2	-2.1	0.8	2.4	-1.0	-0.5	0.5	2.3	1.7	1.8	2.4
Arm predicted mass (left)	0.6	2.9	9.7	0.3	-1.1	-0.7	2.2	0.6	-0.0	-3.1	-0.2	-1.6	-2.4	-2.5	1.0	0.0	0.3	2.7	-1.7	2.5
Depression (Nagel 2018)	0.5	0.7	2.7	-0.2	1.3	0.7	-1.5	-1.6	-0.3	0.0	-0.0	1.2	0.7	1.2	-0.2	0.7	0.9	0.5	0.4	0.0
Bipolar Disorder (2011)	0.5	0.5	1.7	0.2	-0.7	-0.2	-1.1	1.3	0.8	1.0	1.0	-1.3	-0.2	-0.2	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.5	0.6	2.4	0.7	-0.8	-0.1	-0.4	0.4	-0.3	0.2	1.6	-0.2	-0.8	-1.1	0.3	-0.9	-1.4	0.9	1.0	-0.0
Triglycerides	0.5	0.8	5.6	0.7	1.4	1.2	0.3	-0.5	-0.5	-0.7	-0.7	2.4	0.6	-1.2	0.5	0.2	0.5	0.6	-0.2	0.8
Hypothyroidism (self reported)	0.5	1.2	3.3	-0.4	-1.3	-1.1	-0.5	-0.2	-0.3	1.3	0.6	1.1	-1.0	-0.1	-1.4	-1.8	-1.6	-1.5	-1.4	-1.1
Type 2 Diabetes (T2D) (2018)	0.5	0.9	4.9	-0.8	-0.2	-0.4	-1.8	-2.2	-0.8	0.1	-0.6	-0.3	-0.2	-0.8	-1.9	-0.4	-0.6	-0.8	-0.1	-0.3
Relative age of first facial hair	0.5	1.1	2.9	0.4	1.0	1.0	-0.6	0.8	-0.1	-1.0	-1.1	0.7	1.2	-0.6	1.0	0.7	1.5	1.4	1.7	1.4
Diabetes (mother)	0.5	0.6	3.8	-0.2	0.8	0.4	0.4	-0.5	-0.1	-1.0	-1.3	-0.2	0.5	-0.4	-0.4	2.0	1.2	0.1	0.4	0.5
Current tobacco smoking	0.5	0.8	3.0	-0.4	-0.8	-0.3	0.1	1.7	0.9	0.4	0.2	-1.2	0.8	1.7	1.4	0.0	0.7	-0.4	1.0	0.2
Fed-up feelings	0.5	0.9	2.6	-1.6	-0.2	-0.2	-1.6	-1.2	-1.5	-0.5	-0.3	0.1	-1.2	-0.5	-0.2	-1.3	0.3	0.9	-1.1	0.2
Medication: Levothyroxine sodium	0.5	0.9	4.0	-0.0	-1.1	-0.9	-0.7	-0.0	-0.1	0.8	0.5	-0.0	-0.8	-0.0	-1.0	-0.6	-2.0	-1.6	-1.3	-1.2
Sitting height	0.5	3.4	11.2	1.1	0.6	0.8	3.3	0.0	-0.7	-2.9	0.1	-0.5	-2.7	-0.9	2.2	-0.3	0.9	3.4	-1.9	2.6
Waist circumference	0.5	1.7	4.2	1.0	1.4	1.2	0.2	-0.5	-1.5	-1.0	-1.6	0.9	1.9	-1.2	-1.0	0.2	1.6	1.5	1.8	2.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	2.8	-0.1	1.2	0.3	-0.3	-1.7	-0.6	-1.2	-0.1	0.8	0.6	-1.4	-0.5	0.9	1.0	0.3	0.3	0.8
Hair/balding pattern: Pattern 2	0.5	0.6	3.3	0.5	0.9	0.9	0.9	0.1	-1.0	-0.4	-0.2	1.0	0.1	-1.1	0.2	0.4	0.2	0.5	1.8	0.6
Medication: Ramipril	0.5	0.7	1.8	-0.0	0.3	-0.4	-0.9	-0.5	0.2	1.4	0.5	0.3	1.1	0.9	0.3	1.3	-0.4	-1.3	-0.7	-1.3
Fluid intelligence score	0.5	1.1	4.0	-1.0	0.7	0.7	-0.2	-1.4	-0.5	-1.7	-2.0	0.6	-0.6	0.2	0.0	-1.3	1.7	0.5	-0.2	1.4
Arm fat percentage (right)	0.5	1.9	6.5	0.9	2.0	1.7	-0.7	-0.1	-1.1	-0.2	-1.9	0.7	2.5	0.0	-0.8	0.5	1.7	1.5	2.1	1.5
Happiness	0.5	0.6	3.6	0.3	0.6	0.9	1.9	-0.2	-0.6	0.0	0.1	1.6	-0.1	-0.5	0.2	-1.4	0.5	-0.4	0.6	0.1
Mouth/teeth dental problems: Dentures	0.5	0.8	2.3	0.6	-0.3	0.2	-0.3	1.0	1.3	1.5	1.5	-0.2	0.3	0.7	-0.4	-0.7	-1.2	-0.6	-1.0	-1.1
Prospective memory result	0.5	0.6	2.7	0.5	0.9	0.6	-0.3	1.6	0.6	-0.1	-0.9	-0.2	0.9	0.6	0.5	1.6	0.2	0.4	0.5	0.6
Medication: Paracetamol	0.5	0.8	3.0	0.9	1.4	1.2	0.4	-0.3	0.5	-0.7	-0.9	1.7	0.4	-1.5	0.2	0.1	0.5	0.1	1.3	1.1
Gout (self-reported)	0.5	0.7	2.7	-0.2	0.8	0.3	1.0	-1.1	-1.0	-1.7	-0.5	0.2	-1.1	0.0	-0.2	-1.4	0.7	0.4	0.6	0.9
Exposure to tobacco smoke outside home	0.5	0.7	2.6	-1.2	-0.7	-0.5	-1.6	-1.6	-0.6	0.2	-0.3	-0.3	-0.9	-0.5	-0.2	-0.5	-0.4	-1.0	-0.6	-0.9
Worry too long after embarrassment	0.5	0.9	4.4	0.1	-0.0	-0.7	1.2	-1.6	-0.6	1.0	1.3	0.5	-0.3	-0.7	1.0	-2.1	0.6	-0.1	-1.1	-0.3
Medication: Allopurinol	0.5	0.6	3.7	-0.2	0.2	0.3	1.1	-1.0	-1.1	-0.6	0.3	0.5	-0.9	-0.8	-0.6	-1.9	-0.0	-0.4	0.8	0.4
Arm predicted mass (right)	0.5	2.7	9.5	0.1	-0.8	-0.8	2.5	0.1	0.1	-3.1	-0.0	-1.1	-2.2	-2.2	1.1	0.3	0.4	2.5	-2.1	2.3
Age at last live birth	0.5	0.7	3.9	-0.1	0.1	-0.1	0.6	-1.0	0.5	-0.6	-0.5	0.6	-0.4	-2.0	-0.7	-1.0	0.4	1.1	-1.6	0.3
Medication: Aspirin	0.5	0.6	2.2	0.6	0.5	0.2	1.3	-0.5	0.5	0.5	-0.5	0.5	1.5	0.5	-0.2	-1.4	1.3	-0.4	0.7	0.7
Smoking status: Previous	0.5	0.8	4.2	0.4	-0.8	-0.4	1.4	-1.5	0.7	0.4	-0.2	0.9	-0.0	0.2	-1.2	-2.1	-0.1	-0.6	0.3	0.2
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	8.6	0.7	-0.4	0.0	0.9	1.3	-0.0	0.2	-0.0	-0.6	0.4	-2.9	0.3	0.5	-0.5	-0.3	-0.1	-0.0
Guilty feelings	0.5	0.7	5.2	-0.2	0.8	-0.2	0.3	-2.3	0.7	0.9	1.4	0.4	-0.4	-0.2	-0.1	-0.8	0.4	0.5	-0.9	-0.2
Mother’s age at death	0.5	0.6	2.4	0.3	1.1	0.5	-1.0	-0.1	-1.1	-1.0	-0.9	0.1	0.3	-1.1	-0.6	1.6	0.3	-0.2	-0.5	0.1
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.3	0.4	1.0	0.7	-0.4	-0.4	-0.2	-0.9	-0.9	1.2	0.6	-0.9	0.4	1.5	0.9	0.4	0.2	1.0
Supplements: Fish oil (including cod liver oil)	0.5	0.7	3.8	0.0	0.9	0.7	0.3	0.0	-2.0	-0.7	-0.7	1.2	0.6	0.6	-0.8	-0.6	1.1	0.6	0.1	1.0
Medication: Paracetamol	0.5	0.8	2.8	0.8	1.4	1.2	0.5	-0.7	0.2	-0.8	-0.9	1.7	0.3	-1.2	-0.4	-0.5	0.5	-0.5	1.4	1.0
Alcohol drinker status: Never	0.5	0.6	2.9	-0.2	-0.3	-0.4	0.4	-0.1	0.8	1.2	0.9	-1.1	0.5	1.7	-0.3	-0.5	-0.5	-1.1	0.1	-0.8
Unable to work because of sickness or disability	0.5	0.7	4.7	-0.6	-0.4	-0.6	-0.3	-1.4	0.2	0.7	0.6	1.4	-0.1	2.2	-0.4	0.5	-0.4	-0.6	0.2	-0.6
Heart disease (siblings)	0.5	0.6	1.9	-0.2	-0.7	-0.7	1.0	-0.7	0.4	1.2	1.2	-0.4	0.7	-0.1	-1.1	0.2	-0.7	-1.4	-0.2	-0.9
Bipolar Disorder (2018)	0.4	0.7	2.7	-0.1	-0.9	-0.9	-1.6	0.2	0.9	1.0	1.1	-0.8	-0.4	-0.7	0.4	1.1	-0.6	-0.3	0.3	-1.2
Worry (Nagel 2018)	0.4	0.9	4.0	1.0	0.6	0.3	1.4	0.5	0.5	1.2	2.0	1.1	0.9	0.2	1.5	0.9	-0.0	0.2	0.3	-0.4
Alzheimer’s Disease (in mother)	0.4	0.5	1.3	0.8	0.7	1.1	1.0	-0.0	0.7	0.1	-0.2	0.0	0.7	0.1	-0.4	1.0	0.3	-0.7	1.2	-0.7
Alzheimer’s Disease (in father)	0.4	0.5	1.7	-1.1	-0.8	0.1	-0.2	-0.3	-1.3	0.2	-0.2	0.5	-0.9	-1.0	-0.8	-0.7	0.2	-0.3	-0.4	-0.7
Verbal and Numeric Reasoning (VNR)	0.4	0.9	7.9	-0.2	-0.2	0.5	1.2	-0.8	1.4	0.5	-0.1	0.1	-0.7	0.8	0.0	-2.8	0.2	-0.4	-1.2	-0.1
Rheumatoid Arthritis	0.4	0.5	1.6	0.0	-0.0	0.2	-0.5	1.1	0.8	1.0	0.4	-0.6	0.6	1.3	0.3	1.1	-0.0	-0.5	0.9	-0.6
Schizophrenia (2014)	0.4	0.9	2.7	-0.9	-1.5	-0.9	-1.4	-0.1	-0.6	-0.2	0.1	-0.1	-0.6	-1.4	-1.3	1.7	-1.1	-1.1	0.3	-0.8
Blood Eosinophil Count	0.4	2.9	10.0	1.6	1.6	1.2	1.9	0.8	2.0	1.1	-1.1	2.0	3.2	2.4	1.9	-0.1	2.2	1.3	-0.2	1.2
Blood Platelet Count	0.4	4.3	16.5	2.1	2.4	2.5	1.2	1.7	-0.4	0.7	-1.2	1.2	4.1	1.4	1.3	-0.5	3.2	2.5	2.7	2.2
Cardiovascular Disease	0.4	1.5	4.1	1.3	2.0	1.4	-0.6	-1.7	0.6	-0.1	-0.4	0.4	2.0	-0.6	-1.1	1.7	1.0	-1.0	1.3	0.8
Neuroticism	0.4	1.0	4.1	-0.6	-0.7	-0.7	0.3	-1.1	0.1	1.5	1.6	0.6	-0.9	0.4	-0.0	-1.4	-0.4	-0.4	-2.0	-1.1
Number of treatments/medications taken	0.4	0.8	2.2	0.9	0.8	0.4	-0.1	-1.2	0.1	0.2	-0.2	1.5	1.3	-1.1	-1.4	0.1	0.1	-1.2	0.9	0.2
Supplements: Zinc	0.4	0.5	2.4	-0.4	-0.4	0.3	-0.9	-0.8	0.5	0.7	0.5	0.5	-1.0	0.6	-0.2	-0.9	-0.2	0.2	-1.5	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.9	-1.2	0.6	0.2	-0.6	-1.7	-1.0	-0.5	-0.4	0.9	0.1	0.0	0.4	0.7	0.8	0.7	0.7	0.0
Supplements: Glucosamine	0.4	0.5	2.8	-0.0	0.0	-0.8	-0.5	-1.3	0.4	0.5	0.8	0.6	0.3	0.0	-1.0	-0.1	0.3	-0.4	-1.7	-0.2
Body mass index (BMI)	0.4	1.6	5.2	0.6	1.1	1.0	-0.0	0.2	-0.7	-1.7	-2.1	0.3	1.4	-1.1	-0.4	0.8	1.6	1.8	1.6	2.3
Alcohol usually taken with meals	0.4	0.7	2.0	-1.3	0.8	-0.3	-1.3	-0.9	-0.3	-0.8	-0.9	0.7	0.0	0.6	-0.4	1.4	1.1	0.7	0.5	0.6
Nervous feelings	0.4	0.8	4.3	-0.1	-0.2	-0.9	1.0	-0.7	0.8	1.1	2.1	0.9	0.3	-0.2	0.6	-0.3	-0.1	-0.2	-1.6	-0.7
Financial difficulties in last 2 years	0.4	0.5	1.7	-0.9	0.0	-0.2	-0.1	-0.0	-0.5	-0.8	-1.1	0.8	0.1	-0.9	0.4	0.8	1.2	0.3	1.3	0.5
Diabetes (self-reported)	0.4	0.6	3.6	-0.8	0.1	-0.2	-1.2	-1.9	-1.3	-0.1	-1.0	-0.0	-0.0	-0.8	-1.3	-0.3	0.2	-0.2	0.0	0.0
Weight	0.4	2.2	8.7	1.3	1.0	1.1	1.9	0.6	0.0	-2.4	-1.2	-0.2	0.3	-1.4	0.8	0.7	1.4	2.8	0.5	2.9
Falls in the last year	0.4	0.5	3.4	0.6	0.5	0.3	-0.9	-1.3	0.3	-0.1	-0.1	0.1	-0.0	-1.2	-0.6	-0.4	0.1	-0.5	1.8	-0.0
Arm fat mass (right)	0.4	1.5	4.7	0.7	1.2	1.1	0.3	0.1	-0.9	-1.5	-1.7	0.0	1.2	-1.2	-0.5	0.6	1.5	2.0	1.2	2.2
Standing height	0.4	3.7	18.7	1.8	-0.1	0.6	4.3	1.2	1.4	-1.7	1.7	-1.3	-2.1	-1.2	2.9	0.2	-0.2	2.5	-2.6	1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	3.2	-0.4	-0.1	-0.6	0.2	-1.2	0.2	0.5	1.5	0.4	-0.3	-0.6	-0.8	-0.2	-0.6	-0.1	-1.8	-0.6
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.8	-0.2	-0.1	-0.1	1.1	-0.7	-0.4	-0.3	0.1	1.4	-1.2	-1.4	0.1	-1.7	0.1	0.4	-0.4	-0.1
Age at first live birth	0.4	0.7	4.0	-0.5	-0.4	-0.5	-0.1	-1.0	0.3	-0.0	0.9	-0.7	-1.0	-1.3	-0.1	-0.6	-1.0	0.7	-2.0	-0.9
Medication for pain relief, constipation, heartburn	0.4	0.7	2.3	-1.3	-1.0	-0.6	-1.3	0.4	-1.5	-0.4	0.1	-1.5	-1.0	0.4	-0.1	1.0	-0.2	0.3	-0.2	-0.6
Medication: Seretide 50 evohaler	0.4	0.5	1.2	0.8	0.1	0.4	0.9	0.5	1.0	-0.1	0.2	-1.0	1.1	-0.3	0.4	-0.4	0.8	1.1	0.3	1.1
Pulse rate, automated reading	0.4	1.3	6.4	-0.4	0.5	0.4	-1.0	-0.3	-0.7	-2.2	-1.9	0.3	-0.4	-1.5	-0.1	2.5	0.4	0.7	1.6	0.3
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	2.8	1.1	0.3	0.5	0.8	0.5	0.7	0.8	0.2	-0.5	0.9	0.8	0.2	-0.2	0.1	-0.7	-1.7	-0.4
Mood swings	0.4	0.7	1.7	-0.1	0.5	1.1	-0.6	1.2	-0.6	-0.8	-0.8	0.6	0.5	-0.6	0.2	-0.6	1.3	1.1	1.1	1.1
Back pain experienced in last month	0.4	0.6	2.6	1.1	0.8	1.2	1.4	-0.1	-0.5	-0.2	-0.1	1.6	0.5	-0.7	0.5	-0.0	-0.4	-0.4	-0.1	-0.0
Medication: Aspirin	0.4	0.5	2.2	0.2	0.1	-0.2	1.2	-0.9	0.4	0.4	-0.1	0.7	0.8	0.4	-0.1	-1.5	1.1	-0.5	0.0	0.5
Illnesses of father: None of the above (group 1)	0.4	0.5	1.8	-1.3	-0.8	-1.1	-0.6	0.5	0.0	-0.8	-0.3	-0.8	-0.6	0.2	0.1	1.2	-0.6	0.3	-0.2	-0.5
Arm fat mass (left)	0.4	1.5	4.7	0.8	1.4	1.1	0.4	0.1	-0.7	-1.4	-1.5	0.1	1.4	-0.9	-0.3	0.8	1.6	2.2	1.2	2.2
Number of self-reported non-cancer illnesses	0.4	0.7	2.7	0.4	1.0	0.3	-1.3	-1.6	-0.1	0.2	-0.4	0.6	0.7	-0.1	-0.9	1.0	-0.4	-1.5	0.0	-0.7
Hearing aid user	0.4	0.5	3.6	-0.6	-0.3	-0.3	-0.3	0.4	-0.4	-1.3	-0.7	-0.4	-0.7	-1.9	0.4	-0.2	-0.0	0.1	-0.3	0.8
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.2	0.2	-0.7	-0.8	-0.5	-0.4	-0.2	0.8	1.0	-0.5	-0.2	-0.1	-1.1	0.9	-0.3	-0.9	0.7	-1.0
High cholesterol (Self-reported)	0.4	0.6	1.7	-0.1	-0.3	-0.7	-0.9	-1.0	-1.1	0.1	0.4	-1.3	0.7	0.3	-0.6	1.2	0.2	-1.3	1.1	0.3
Illnesses of father: High blood pressure	0.4	0.5	1.8	0.2	-0.9	-0.1	0.1	0.1	-0.6	-0.0	0.7	-1.3	-1.2	-0.5	0.0	-0.4	-1.2	-0.9	-0.4	-0.3
Number of operations (self-reported)	0.4	0.7	5.3	1.1	0.5	0.9	0.1	-0.3	0.8	0.2	-0.0	0.1	1.2	0.2	-0.1	-0.7	0.1	-0.9	2.3	0.4
Fractured/broken bones in last 5 years	0.4	0.5	3.2	0.4	-0.1	0.9	0.0	0.8	0.5	-0.5	-0.3	-0.1	0.7	-0.6	1.8	-0.9	0.4	0.8	0.6	0.7
Alcohol drinker status: Previous	0.4	0.5	1.8	-1.1	0.3	-0.5	-0.3	-0.6	-1.1	-0.9	-0.9	-1.3	-0.1	0.2	-0.6	0.1	0.8	0.5	-0.2	0.3
Reaction Time	0.3	0.5	2.2	0.2	-1.0	-0.7	-0.8	-0.4	1.5	0.5	0.8	-0.2	-0.9	0.4	-0.6	0.1	-1.1	-0.4	0.0	-0.6
Body Mass Index (BMI) (2010)	0.3	0.4	1.7	0.9	0.1	0.2	0.2	0.1	1.3	0.1	0.9	0.8	0.1	-0.9	-1.2	-0.1	-0.3	0.1	0.3	0.2
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.0	0.5	-0.7	-0.6	0.3	0.5	0.8	-0.3	0.2	-1.0	0.4	-0.8	0.7	0.5	0.4	-0.4	0.2	0.4
Blood White Count	0.3	2.0	7.3	1.2	0.0	1.2	1.3	2.4	1.7	-0.8	-0.4	-0.9	1.0	2.5	2.7	0.6	1.2	1.3	0.9	1.1
Smoking Status	0.3	0.8	2.8	0.5	-1.2	-0.3	1.0	0.4	0.9	1.6	0.8	-0.1	1.0	0.2	-0.0	-1.7	0.4	-1.1	1.3	-0.3
Hand grip strength (left)	0.3	0.7	2.9	1.1	-1.0	-0.6	1.2	0.6	0.8	0.5	1.7	-0.4	-0.6	-0.1	1.5	-0.7	-0.8	0.3	-0.4	0.0
Hearing difficulty/problems: Yes	0.3	0.5	1.5	-0.8	-0.4	-0.8	1.0	1.0	-0.4	-0.7	-0.5	-0.7	0.6	-0.6	0.1	-0.2	0.7	-0.2	1.2	0.5
Diabetes (father)	0.3	0.4	4.0	-0.6	0.1	-0.4	-2.0	-0.6	-0.5	0.5	-0.0	-0.1	0.1	-0.1	-0.5	-1.0	0.3	0.0	0.2	0.1
Maternal smoking around birth	0.3	0.5	2.4	0.9	0.4	0.8	0.4	1.0	0.1	1.1	0.4	-0.7	0.9	-0.1	1.5	-0.2	-0.1	0.2	0.4	-0.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	2.8	-0.1	0.1	0.2	0.9	-0.6	-0.0	-0.2	-0.2	1.7	-0.8	-0.1	0.1	-0.7	0.7	0.3	-0.4	0.4
Number of incorrect matches in round	0.3	0.5	1.8	-0.6	-0.5	-1.3	-0.6	-0.4	0.8	1.2	0.9	0.5	0.3	-0.7	-0.7	-0.4	0.1	-1.2	-0.3	-0.5
Medication: Simvastatin	0.3	0.5	1.4	0.3	-0.5	-0.4	0.1	-0.2	0.1	-0.0	-0.8	-0.9	0.8	-0.8	-1.1	1.1	-0.4	-0.9	1.2	0.2
Neuroticism score	0.3	0.6	2.7	-1.0	0.1	-0.5	0.1	-1.6	-0.9	0.3	0.8	1.1	-0.7	-0.4	-0.1	-0.8	0.4	-0.1	-1.1	-0.4
Worrier / anxious feelings	0.3	0.7	2.5	0.0	1.6	1.1	0.4	-0.4	-0.3	-0.9	-0.5	1.5	0.5	0.7	0.6	0.9	0.8	0.7	-0.5	0.4
Medication: Cholesterol lowering	0.3	0.5	2.2	0.6	-0.2	-0.9	0.1	-0.8	-0.2	1.5	0.9	0.5	1.2	-1.3	0.3	-0.5	0.1	-0.7	0.1	-0.1
Medication: Lansoprazole	0.3	0.4	1.5	0.9	-0.3	-0.2	0.4	-0.5	0.3	0.5	0.3	0.2	1.0	0.2	-1.2	0.4	-0.2	-0.8	0.8	-0.3
Length of working week for main job	0.3	0.4	2.3	-0.1	-0.2	-0.6	-1.5	-0.3	0.4	-0.3	-0.4	-0.2	-0.2	-0.7	1.1	-0.3	0.7	0.7	-0.3	0.5
Tense / ‘highly strung’	0.3	0.5	1.8	-0.7	0.7	-0.1	0.3	-0.2	-1.1	-0.6	1.0	0.5	0.0	-1.2	0.7	1.3	0.2	0.0	0.1	0.6
Hair/balding pattern: Pattern 4	0.3	0.8	3.8	-0.9	-0.2	0.1	-2.0	0.1	-1.1	-0.7	-0.9	-0.1	0.2	0.7	-1.8	-0.4	0.8	-0.1	0.7	0.7
Peak expiratory flow (PEF)	0.3	0.8	5.5	0.9	-0.5	-0.0	1.3	-0.3	0.9	-0.3	0.5	0.3	-0.1	-0.5	1.2	2.3	-0.4	-0.6	-1.1	-0.3
Birth weight	0.3	0.5	2.4	0.6	-0.9	-0.4	0.6	0.6	1.3	0.4	1.6	-1.2	-0.4	0.0	0.1	-0.2	-1.1	-0.4	-0.1	-0.3
Wheeze or whistling in the chest in last year	0.3	0.5	2.2	-0.5	0.3	-0.3	-0.1	0.1	-0.2	-1.2	-0.7	-0.5	0.6	0.4	0.4	0.3	0.7	1.5	-0.0	1.4
Health satisfaction	0.3	0.4	1.9	-0.1	0.5	0.7	0.3	-0.6	-1.2	-0.6	0.1	0.9	0.0	-0.4	0.0	-0.5	0.7	-0.0	1.4	0.6
Qualifications: College or University degree	0.3	0.8	3.6	1.0	0.6	0.5	1.9	0.6	-0.1	0.2	0.3	0.7	0.1	0.1	1.7	-1.3	0.4	1.2	-1.3	0.1
Medication: Blood pressure	0.3	0.6	2.8	-0.6	-0.5	-1.3	-0.8	-1.7	-1.0	0.3	-0.0	0.5	0.3	-0.8	-0.5	0.3	0.3	-0.4	-1.3	-0.2
Overall health rating	0.3	0.6	1.9	-0.7	0.4	-0.0	-0.5	-1.3	-1.2	-1.1	0.1	0.3	0.4	-0.5	-0.5	1.1	1.4	0.5	0.7	1.0
Had major operations	0.3	0.4	1.5	0.4	0.3	0.7	-0.2	-0.7	1.2	0.8	0.6	0.2	0.5	0.3	0.4	-1.1	-0.0	-0.6	0.7	0.1
Leg pain on walking	0.3	0.4	1.6	0.3	-0.3	-0.3	-0.8	-0.0	1.2	0.3	0.4	0.0	0.4	0.1	0.3	0.3	0.8	-0.2	1.3	1.0
Long-standing illness, disability or infirmity	0.3	0.4	2.1	0.4	0.3	0.0	-0.5	-1.4	0.7	0.4	-0.1	1.3	0.5	-1.1	-0.3	-0.4	0.1	-0.4	-0.0	-0.0
Diabetes diagnosed by doctor	0.3	0.5	2.0	-0.1	0.2	0.1	-1.3	-1.4	-1.3	0.0	-1.0	0.4	0.7	-0.8	-0.9	-0.1	0.4	-0.1	0.7	0.5
Qualifications: nursing, teaching	0.3	0.5	2.2	0.2	0.5	0.6	-1.4	-1.5	-0.5	-0.0	-0.3	0.0	-1.0	-0.6	0.1	-0.3	0.2	0.7	-0.9	-0.1
Wears glasses or contact lenses	0.3	0.4	2.5	0.7	0.0	-0.3	-0.3	-0.3	-0.6	0.4	0.2	-0.1	1.1	0.3	0.8	1.6	-0.2	-0.7	-0.3	-0.2
Medication: Lisinopril	0.3	0.4	1.4	1.1	-0.2	0.2	0.0	0.8	0.1	-0.3	-0.2	0.2	1.0	-0.7	0.3	1.2	0.5	0.5	0.7	1.0
Irritability	0.3	0.5	2.1	-0.9	-0.6	-0.0	-0.3	-0.7	-0.5	-0.6	0.2	-0.5	-1.0	-1.4	-0.5	-0.7	-0.5	0.3	-1.3	-0.1
Risk taking	0.3	0.5	3.7	-0.4	-0.1	0.1	-0.3	0.7	0.2	-0.5	-0.6	0.0	0.2	0.8	0.8	1.0	0.8	-0.1	1.9	0.2
Myopia	0.3	0.4	2.1	0.5	0.6	0.2	0.9	-0.3	-0.2	0.6	0.3	-0.2	0.5	-1.1	-0.3	-0.8	0.4	-0.2	-1.5	-0.4
Pain experienced in last month	0.3	0.5	3.8	0.4	-0.2	-0.4	-0.3	-0.2	0.3	1.4	0.6	-0.9	0.0	-0.1	-0.0	-1.9	-0.3	-0.3	-0.0	-0.8
Basal cell carcinoma (self-reported)	0.3	0.3	1.2	-0.3	0.3	-0.3	-0.0	-1.0	-0.4	0.3	-0.1	0.4	0.5	1.1	-0.7	0.5	0.0	-0.9	-0.4	-0.6
Depressed Affect (Nagel 2018)	0.2	0.3	1.7	-0.1	0.5	0.8	-1.3	-0.2	-0.8	0.1	-0.2	0.8	0.2	-0.3	-0.5	-0.4	0.9	0.4	0.1	0.4
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.8	-0.5	-0.6	0.2	0.7	-0.0	1.2	-0.1	-0.3	-0.7	-0.5	-0.3	1.4	-1.3	-0.0	0.4	-1.4	-0.2
Neuroticism (Nagel 2018)	0.2	0.4	2.1	0.5	0.3	0.5	0.1	-0.7	0.0	1.3	1.5	1.2	0.5	0.0	0.7	-0.3	0.5	0.0	-0.2	-0.5
Alzheimer’s Disease (including proxy)	0.2	0.3	1.0	-0.1	-0.3	0.7	1.0	0.0	-0.1	0.3	-0.3	0.4	-0.1	-0.6	-0.7	-0.1	0.1	-0.8	0.3	-1.0
BMI	0.2	1.4	6.7	0.3	0.7	0.1	1.1	0.0	0.1	-1.6	-1.5	0.4	1.3	-1.2	-0.9	-0.5	1.6	1.9	0.8	2.6
Height	0.2	4.7	31.3	1.4	0.0	-0.1	5.6	0.9	1.6	-1.7	1.3	-0.4	-1.5	-1.6	3.9	0.6	0.5	2.1	-3.3	1.6
Systolic Blood Pressure	0.2	1.1	3.5	-0.3	1.9	1.3	-1.4	-1.0	-0.5	-0.0	-0.9	1.2	1.5	0.2	-1.3	0.1	1.5	-0.1	1.4	0.5
Allergy or Eczema	0.2	0.5	4.2	0.6	0.5	0.5	0.2	0.2	-0.7	-0.1	0.2	0.8	0.6	-0.2	-0.8	2.1	-0.3	-0.6	-0.3	-0.1
Respiratory disease	0.2	0.5	1.8	0.3	0.2	0.3	-0.4	-0.1	0.6	-0.5	-0.3	-0.9	0.4	1.3	0.9	1.3	0.6	1.2	0.1	0.8
Hand grip strength (right)	0.2	0.6	1.6	0.1	-0.9	-1.0	1.2	0.3	0.6	-0.5	1.0	-1.0	-1.1	0.3	1.3	0.2	-0.4	0.1	-0.3	0.3
Taking other prescription medications	0.2	0.3	1.3	0.5	0.2	0.0	-0.3	-0.7	0.6	0.3	0.0	0.1	0.5	-0.3	-1.2	0.1	-0.8	-1.0	-0.4	-0.8
Serious illness, injury or assault to yourself	0.2	0.2	1.4	-0.4	0.2	0.0	0.2	-0.8	-0.8	0.1	-0.4	-0.2	0.1	-0.4	-0.2	-1.2	0.4	0.0	-0.2	0.2
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.5	1.2	0.2	0.5	0.5	0.9	0.2	0.6	1.0	0.9	0.6	0.3	-0.5	1.2	-0.7	-0.5	-0.5	-0.3
Hearing difficulty/problems with background noise	0.2	0.3	1.0	-1.0	-0.5	-0.7	0.1	0.2	-0.4	-0.6	-0.7	-0.9	-0.5	-0.8	-0.1	0.4	0.8	0.4	0.4	0.6
Had other major operations	0.2	0.2	1.0	0.5	-0.5	0.3	0.1	-0.2	-0.0	0.6	0.7	0.7	0.1	0.1	0.5	-0.8	0.1	0.2	1.0	0.1
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.3	-0.2	-0.0	-0.3	-0.2	-0.9	-0.1	0.2	0.9	0.5	-0.0	0.6	-0.2	-1.1	0.5	0.8	-0.0	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.4	-0.8	0.5	0.5	0.1	-1.0	-0.8	-1.2	-0.3	0.6	-0.3	-0.4	-0.2	0.5	0.4	-0.0	-0.3	0.5
Qualifications: A levels/AS levels or equivalent	0.2	0.5	2.1	0.5	0.9	0.7	1.1	-0.2	0.1	0.1	0.3	1.4	-0.0	-0.2	0.2	-1.4	0.9	0.8	-0.8	0.2
Asthma	0.2	0.5	2.4	-1.1	-0.1	-0.3	-1.6	-1.2	-0.9	-0.5	-0.9	-0.3	0.3	0.7	-0.1	0.5	0.5	0.1	-0.3	-0.1
Number of children fathered	0.2	0.2	1.7	0.5	0.3	-0.0	0.3	0.0	0.8	0.5	0.7	0.0	-0.1	1.3	0.4	-0.1	-0.4	0.5	0.1	0.1
Chest pain or discomfort	0.2	0.2	1.2	-0.4	0.1	-0.4	-0.3	-0.6	-0.6	-0.2	0.3	1.1	0.1	-0.3	-0.6	-0.4	0.3	-0.2	0.6	0.7
Average weekly red wine intake	0.2	0.3	3.6	0.2	0.0	0.1	-0.6	-0.4	-0.1	0.4	0.0	-0.1	-0.4	1.9	0.1	0.7	0.0	0.4	0.8	0.1
Ever had bowel cancer screening	0.2	0.3	1.4	0.4	-0.2	0.4	0.4	-0.5	0.8	0.3	0.2	0.4	-0.4	0.6	-0.4	-0.1	-1.2	-0.7	-0.1	-0.7
Asthma (self-reported)	0.2	0.4	2.6	-0.8	-0.1	-0.3	-1.6	-1.1	-0.8	-0.5	-0.7	-0.4	0.2	0.4	0.1	0.6	0.2	0.1	-0.1	-0.1
Tanning	0.1	1.5	6.6	-0.2	1.0	0.8	2.6	0.8	-1.7	-1.4	-0.9	0.5	0.4	-0.4	-0.5	0.2	1.3	0.6	2.2	1.9
Systolic blood pressure, automated reading	0.1	0.3	1.0	0.1	0.7	0.9	-1.0	0.2	-0.3	-0.2	-0.5	0.6	0.6	-0.4	-0.7	-0.6	0.6	0.5	0.4	0.4
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	0.6	0.1	-0.4	-0.2	-0.2	-0.5	-0.5	0.8	0.1	0.5	0.0	-0.5	-0.3	-0.6	0.0	-0.1	-0.3	-0.6
Allergy	0.1	0.3	1.2	-0.2	-0.4	-0.7	-0.3	-0.3	0.2	0.4	-0.0	-0.3	-0.5	-0.9	-0.3	-1.1	-0.3	-0.6	1.0	-0.4
Comparative height size at age 10	0.1	0.7	2.6	1.4	0.3	0.5	1.6	-0.2	0.9	-0.8	1.1	-0.6	-0.3	-1.1	0.6	1.0	-0.3	0.6	-1.2	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.5	0.1	-0.4	-0.2	-0.6	-0.1	-0.4	0.2	-0.5	0.5	0.0	0.7	-0.3	-0.4	-0.2	0.1	0.0	0.1
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	1.1	7.6	1.0	0.2	0.9	1.3	2.8	2.1	-0.1	0.2	-0.6	1.0	0.0	1.2	0.7	0.5	0.2	-0.1	0.4

Hub : Genes

TSPAN9

Models

Trait associations