Best TWAS P=1.06e-18 · Best GWAS P=1.85e-20 conditioned to 0.00466
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | GJA5 | 0.16 | 0.07 | lasso | 6 | 0.04 | 0.0029 | 8.7 | -8.8 | 1.1e-18 | -0.95 | 0.00 | 0.99 | TRUE |
2 | GTEx | Esophagus Muscularis | RP11-433J22.2 | 0.15 | 0.02 | lasso | 7 | 0.03 | 0.0063 | 8.7 | -8.5 | 1.6e-17 | -0.84 | 0.01 | 0.98 | FALSE |