TWAS hub - GJA5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Muscularis	0.1640	0.0610	0.00550	0.065	NA	0.005	NA	0.036	8.5e-05	NA	0.1600	NA	0.00290
2	GTEx	Testis	0.2570	0.0940	0.00048	0.092	NA	0.044	NA	0.057	6.8e-05	NA	0.0051	NA	0.00160
3	TCGA	Breast Invasive Carcinoma	0.0252	0.0156	0.00065	0.016	0.009	0.011	NA	0.013	2.6e-04	0.0051	0.0020	NA	0.00075

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Reproduciblity of spirometry measurement using ERS/ATS criteria	8.8	10.4	16.6	-2.0	-4.1	3.3
Medication: Omeprazole (e.g. Zanprol)	5.5	6.7	17.9	-0.6	-1.4	4.2
Schizophrenia vs Biploar Disorder	4.6	6.0	7.1	2.7	2.5	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	4.3	6.6	8.7	-2.7	-2.0	3.0
Number of incorrect matches in round	4.2	6.9	7.8	-2.8	-2.6	2.5
Qualifications: CSEs or equivalent	3.9	5.2	8.4	0.3	-2.9	2.6
Medication: Metformin	3.7	5.3	8.5	-0.4	-2.7	2.9
Migraine (self-reported)	3.6	4.4	7.5	1.6	-1.8	2.7
Medication: Omeprazole	3.4	4.0	11.4	-0.1	-0.8	3.4
Suffer from ‘nerves’	3.3	5.2	9.5	2.0	3.1	-1.5
Body Mass Index (BMI) (2010)	3.1	4.2	6.1	-1.7	-1.9	2.5
Commuting to job workplace: Car/motor vehicle	3.1	3.5	8.2	-0.8	-1.3	2.9
Heart attack/myocardial infarction (self-reported)	3.0	3.8	6.1	-0.7	-2.5	2.2
Illness, injury, bereavement, stress in last 2 years	2.9	3.6	4.9	2.2	2.2	-1.0
Blood Red Count	2.8	27.5	78.0	-8.8	-2.0	0.7
Serious illness, injury or assault to yourself	2.8	3.3	4.9	-1.2	-2.2	1.9
Heart attack	2.8	3.6	5.4	-0.5	-2.3	2.3
Medication: Amlodipine	2.7	3.9	8.6	0.5	2.9	-1.6
Average weekly fortified wine intake	2.6	3.1	8.4	-2.9	0.4	-0.8
Commuting to job workplace: Public transport	2.6	3.1	6.0	1.3	1.3	-2.5
Pain experienced in last month	2.6	4.4	7.1	1.0	2.7	-2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.5	2.9	5.8	-0.8	-1.5	2.4
Unable to work because of sickness or disability	2.5	3.2	6.4	-0.3	-1.8	2.5
Depression (self-reported)	2.4	2.9	5.8	-0.8	-1.5	2.4
Medication: Lansoprazole	2.4	2.7	4.9	-2.2	-0.8	1.6
Lung cancer (father)	2.4	2.8	6.6	2.6	1.2	0.4
Comparative body size at age 10	2.4	6.6	11.2	1.7	3.4	-2.4
Pulse rate, automated reading	2.4	7.8	10.8	-1.9	-3.3	3.0
Medication: Atorvastatin	2.4	3.0	6.6	-0.8	-1.4	2.6
Schizophrenia (2014)	2.3	5.0	7.0	1.5	2.6	-2.4
Ever depressed for a whole week	2.3	2.9	5.9	1.2	-1.1	2.4
Mother’s age at death	2.1	2.6	3.8	-0.9	-2.0	1.8
Medication: Blood pressure	2.0	3.8	6.1	1.6	2.5	-1.7
Severe depression (siblings)	1.9	2.1	2.9	-1.3	-1.3	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.4	5.2	-0.8	-1.2	2.3
Diabetes diagnosed by doctor	1.9	3.1	7.2	-0.2	-1.4	2.7
Pack years of smoking	1.9	2.7	3.6	1.9	-1.3	1.7
Pain all over the body in last month	1.8	1.9	2.8	-0.9	-1.7	1.4
Illnesses of siblings	1.8	2.5	6.4	0.0	-2.5	1.1
Medication: Seretide 50 evohaler	1.8	2.1	4.6	0.4	-1.2	2.1
Guilty feelings	1.8	2.8	6.4	1.1	2.5	-0.8
Pack years adult smoking proportion	1.7	2.6	3.8	1.3	-1.5	2.0
Tinnitus: Yes, but not now, but have in the past	1.7	1.8	2.9	1.3	0.9	-1.7
Diabetes (self-reported)	1.7	2.6	5.1	-1.1	-1.2	2.2
High blood pressure (siblings)	1.7	2.4	4.7	1.0	2.2	-1.3
Medication for cholesterol	1.7	2.5	3.6	-1.9	-1.8	0.7
Alzheimer’s Disease (in father)	1.6	1.8	3.3	0.2	1.8	-1.4
Schizophrenia (2018)	1.5	3.0	4.5	0.6	2.1	-2.1
Falls in the last year	1.5	2.0	3.4	1.1	-1.2	1.9
Headache pain in last month	1.5	2.6	4.0	1.0	-1.7	2.0
Ulcerative Colitis (UC)	1.4	2.6	4.5	-0.2	1.8	-2.1
Diabetes (father)	1.4	1.7	2.2	-1.4	1.0	-1.5
Medication: Levothyroxine sodium	1.4	2.3	2.8	-1.5	-1.4	1.7
Financial difficulties in last 2 years	1.4	1.9	2.5	0.9	-1.6	1.6
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	4.8	-0.6	-1.8	2.2
Supplements: Vitamin C	1.4	1.7	2.7	-0.7	-1.6	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	2.0	-1.4	-0.9	1.4
Mineral and other dietary supplements	1.4	1.9	4.3	-0.4	2.1	-1.1
Supplements: Fish oil (including cod liver oil)	1.4	1.8	2.9	0.3	-1.7	1.5
Myopia	1.4	2.0	3.2	-0.8	1.4	-1.8
Hair/balding pattern: Pattern 2	1.3	1.6	2.3	-0.9	-1.5	1.3
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	4.2	0.2	-0.8	2.0
Ever highly irritable/argumentative for 2 days	1.3	1.5	4.0	-0.2	2.0	-0.8
Smoking status: Previous	1.3	1.9	3.2	0.8	1.8	-1.4
Breast cancer (self-reported)	1.3	1.6	4.1	-2.0	0.8	-0.3
Basal cell carcinoma (self-reported)	1.3	1.5	3.0	-0.8	-1.7	1.0
Irritable Bowel Disease (IBD)	1.2	2.9	4.5	-1.2	1.7	-2.1
Mean Putamen Volume	1.2	1.4	2.9	0.7	0.8	-1.7
Hypothyroidism (self reported)	1.2	2.7	4.4	-0.4	-2.1	1.8
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	4.4	-0.4	-0.4	2.1
Neuroticism score	1.2	2.6	4.8	2.2	1.7	0.4
Mouth/teeth dental problems: Dentures	1.2	2.0	3.2	0.5	-1.5	1.8
Eye problems/disorders: None of the above	1.2	1.3	2.0	-0.1	1.4	-1.4
Worry (Nagel 2018)	1.1	2.3	5.2	1.3	2.3	-0.2
LDL Cholesterol	1.1	1.7	2.6	1.2	1.6	-1.1
Neuroticism	1.1	2.7	6.4	2.5	1.2	0.6
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	1.8	1.3	1.3	-0.6
Prospective memory result	1.1	1.3	2.5	1.6	1.1	-0.5
Medication for pain relief, constipation, heartburn	1.1	1.9	2.9	1.7	-0.4	-1.6
Mouth/teeth dental problems: Mouth ulcers	1.1	1.7	4.2	-2.1	1.0	0.1
Medication: Lisinopril	1.1	1.5	4.1	2.0	0.5	0.1
Supplements: Calcium	1.1	1.3	1.9	-1.4	-1.3	0.4
Neuroticism (Nagel 2018)	1.0	2.2	4.9	2.2	1.3	-0.2
Taking other prescription medications	1.0	1.6	4.2	-0.7	-0.4	2.0
Past tobacco smoking	1.0	1.9	4.7	-0.5	-2.2	0.9
Illnesses of mother	1.0	1.2	3.4	-1.8	0.3	-0.2
Exposure to tobacco smoke at home	1.0	1.1	2.6	0.0	-0.9	1.6
Breastfed as a baby	1.0	1.2	1.6	-0.9	1.3	-1.1
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	1.7	-1.3	-0.8	1.3
Neck or shoulder pain in last month	1.0	1.5	3.3	0.2	-1.1	1.8
Fasting Glucose	0.9	1.1	1.7	0.4	1.3	-1.2
Ever had hysterectomy (womb removed)	0.9	1.0	2.9	-0.2	1.7	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	3.8	-1.9	-1.0	1.3
Father’s age at death	0.9	1.2	1.9	-0.3	1.4	-1.3
Number of children fathered	0.9	1.0	1.8	-0.5	-1.0	1.3
Medication: Allopurinol	0.9	1.2	1.5	1.2	-0.9	1.2
Friendships satisfaction	0.9	1.2	2.8	1.7	0.4	0.7
Coronary Artery Disease (CAD)	0.8	1.0	1.1	-1.0	-0.9	1.0
Medication: Co-codamol	0.8	0.9	1.8	-0.7	-0.5	1.4
Fed-up feelings	0.8	1.4	3.1	-0.6	-0.9	1.8
Nervous feelings	0.8	1.5	3.8	0.3	2.0	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	2.9	-0.9	0.2	1.7
Mouth/teeth dental problems	0.8	1.2	2.6	0.6	0.7	-1.6
Mouth/teeth dental problems: Loose teeth	0.8	0.9	1.7	0.1	-1.3	1.0
Emphysema/chronic bronchitis	0.8	0.9	1.0	-0.9	-1.0	0.9
Overall health rating	0.8	1.7	4.5	0.4	-0.7	2.1
Medication: Aspirin	0.8	1.1	2.6	-1.6	0.7	0.2
Medication: Gliclazide	0.8	0.9	1.5	-1.2	-0.8	0.6
Ever taken oral contraceptive pill	0.8	0.9	1.5	0.5	-1.2	1.0
Fractured/broken bones in last 5 years	0.8	1.0	2.5	-0.3	-1.6	0.6
Neuroticism (2016)	0.7	0.9	2.3	-0.3	1.5	-0.7
Primary Biliary Cirrhosis	0.7	1.0	1.5	0.7	0.9	-1.2
Type 2 Diabetes (T2D) (2018)	0.7	1.4	3.5	0.1	-0.8	1.9
Average weekly spirits intake	0.7	0.8	2.0	-0.1	-0.7	1.4
Sensitivity / hurt feelings	0.7	1.2	3.2	1.8	0.4	0.2
Medication for hormone replacement therapy	0.7	0.8	1.4	-0.2	1.2	-1.0
Vitamin and mineral supplements	0.7	1.0	1.2	1.0	1.1	-0.9
Maternal smoking around birth	0.7	1.0	2.0	1.4	1.0	0.1
High blood pressure	0.7	1.9	3.8	1.0	1.9	-0.9
Chronic bronchitis/emphysema (father)	0.7	0.8	1.0	0.7	1.0	-0.9
Time employed in main current job	0.7	0.8	1.6	-0.8	-0.2	1.3
Worrier / anxious feelings	0.7	1.4	2.6	1.2	1.6	-0.1
Medication: Cholesterol lowering	0.7	1.0	2.9	-0.4	-0.3	1.7
Age at first live birth	0.7	1.3	2.5	0.0	1.2	-1.6
Family relationship satisfaction	0.7	0.8	2.0	1.4	0.7	0.1
Loneliness, isolation	0.7	0.9	1.6	-0.7	0.8	-1.3
Financial situation satisfaction	0.7	0.8	1.7	-0.0	-0.9	1.3
Number of operations (self-reported)	0.7	1.1	1.3	1.1	-1.0	1.0
Irritability	0.7	1.2	2.5	1.6	0.1	1.0
Bipolar Disorder or Schizophrenia	0.6	1.5	3.0	0.3	1.2	-1.7
Crohns Disease (2017)	0.6	1.3	2.0	-1.2	0.8	-1.4
Crohns Disease (2012)	0.6	0.9	1.7	-0.9	-1.3	0.2
HbA1C	0.6	0.6	1.4	-0.4	-1.2	0.6
Rheumatoid Arthritis	0.6	0.8	1.1	-0.8	-1.0	0.8
Supplements: Glucosamine	0.6	0.8	2.1	-0.1	-1.5	0.6
High blood pressure (mother)	0.6	0.8	2.2	1.5	-0.3	-0.4
Alcohol usually taken with meals	0.6	1.0	2.0	-0.6	-0.8	1.4
Had menopause	0.6	0.7	1.8	-0.3	1.4	-0.5
Alcohol intake versus 10 years previously	0.6	0.9	2.2	-0.3	-1.5	0.7
Number of live births	0.6	0.9	1.2	0.8	-1.1	0.9
Noisy workplace	0.6	0.8	1.8	0.1	-1.3	0.7
Birth weight of first child	0.6	1.1	3.0	-0.4	-1.7	0.1
Medication: Paracetamol	0.6	1.0	1.1	-1.1	1.0	1.0
Number of full sisters	0.6	0.7	1.5	-0.0	0.7	-1.2
Chest pain or discomfort	0.6	0.9	1.6	-0.7	-0.7	1.3
Leg pain on walking	0.6	0.8	2.0	-0.4	-0.5	1.4
Medication: Aspirin	0.6	0.8	1.6	-1.3	0.8	0.1
Illnesses of father: Heart disease	0.6	0.8	1.7	0.1	-1.3	0.9
Osteoarthritis (self-reported)	0.6	0.8	1.5	0.1	-0.9	1.2
Miserableness	0.6	1.1	2.6	1.6	0.7	0.4
Medication: Paracetamol	0.6	1.0	2.0	-0.6	1.4	0.8
Alcohol drinker status: Never	0.6	0.7	1.5	-1.2	-0.5	0.7
Alzheimer’s Disease (in mother)	0.5	0.6	1.0	-1.0	0.4	-0.8
Frequency of depressed mood in last 2 weeks	0.5	0.6	1.1	-0.9	0.1	1.0
Age when periods started (menarche)	0.5	1.3	2.0	-1.0	1.4	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.4	-0.3	-0.3	1.5
Tense / ‘highly strung’	0.5	0.8	1.3	-0.8	1.2	0.7
Hair/balding pattern: Pattern 4	0.5	1.2	2.0	-0.1	1.2	-1.4
Loud music exposure frequency	0.5	0.6	1.5	1.2	-0.4	0.3
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.0	0.1	-1.0	-0.9
Exposure to tobacco smoke outside home	0.5	0.6	0.8	-0.7	-0.7	-0.9
Pulse wave peak to peak time	0.5	0.5	0.6	0.7	-0.7	-0.8
Alcohol intake frequency.	0.5	1.3	2.1	-0.2	-1.3	1.4
Hypertension (Self-reported)	0.5	1.3	3.5	0.5	1.9	-0.5
Long-standing illness, disability or infirmity	0.5	0.8	1.8	-0.5	0.4	1.4
Commuting to job workplace: Walk	0.5	0.5	0.6	0.6	-0.8	-0.7
Illnesses of father: None of the above (group 1)	0.5	0.6	1.6	-0.2	-0.5	1.3
Hearing aid user	0.5	0.5	1.1	-1.1	-0.6	0.3
Eye problems/disorders: Glaucoma	0.5	0.5	1.0	-0.3	0.8	-1.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	0.7	-0.7	0.9	0.8
Ever smoked	0.5	1.0	2.5	0.4	1.6	-0.4
Average weekly beer plus cider intake	0.5	0.7	1.6	-1.3	0.5	-0.6
Cholesterol lowering medication	0.5	0.7	1.6	0.2	-0.6	1.3
Intelligence (Savage-Jansen 2018)	0.4	1.1	1.9	0.7	-0.9	1.4
Alzheimer’s Disease (including proxy)	0.4	0.6	1.2	-0.3	1.1	-0.8
Breast Cancer	0.4	0.9	1.7	1.1	1.3	-0.1
Ulcerative Colitis	0.4	0.6	1.1	0.4	1.0	-0.7
Systolic Blood Pressure	0.4	1.9	5.4	2.3	0.6	-0.0
Smoking Status	0.4	0.9	1.8	-0.5	1.4	-0.7
Cardiovascular Disease	0.4	1.2	2.7	0.8	1.6	-0.6
Respiratory disease	0.4	0.9	1.5	0.4	-1.1	1.2
Number of treatments/medications taken	0.4	0.7	1.7	0.6	0.3	1.3
Impedance of leg (right)	0.4	2.2	4.1	-2.0	-0.8	1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	1.6	-1.3	-0.4	0.8
Hair/balding pattern: Pattern 3	0.4	0.6	1.5	0.3	-0.6	1.2
Pulse wave Arterial Stiffness index	0.4	0.5	0.9	-0.7	0.9	0.4
Pulse wave reflection index	0.4	0.5	1.4	-0.4	1.2	-0.0
Worry too long after embarrassment	0.4	0.7	1.1	0.8	0.5	1.0
Wheeze or whistling in the chest in last year	0.4	0.7	1.2	0.5	-1.1	0.8
Shortness of breath walking on level ground	0.4	0.5	1.2	0.2	1.1	-0.5
Medication: Blood pressure	0.4	0.7	2.1	0.2	-0.3	1.5
Comparative height size at age 10	0.4	2.1	4.2	-1.2	0.7	-2.1
Average weekly red wine intake	0.4	0.6	1.2	-0.7	-0.4	-1.1
Ever had bowel cancer screening	0.4	0.5	0.8	0.6	-0.6	0.9
Eye problems/disorders: Cataract	0.4	0.5	0.8	0.2	-0.8	0.9
Ever had prostate specific antigen (PSA) test	0.4	0.4	1.2	-0.0	1.1	0.3
Diastolic blood pressure, automated reading	0.4	1.3	2.6	1.6	-1.0	0.6
Vascular/heart problems diagnosed by doctor	0.4	1.2	2.1	-1.2	-1.4	0.3
Heart disease (siblings)	0.4	0.5	1.3	-0.2	1.1	0.4
Depression (Nagel 2018)	0.3	0.4	1.3	-0.1	-0.1	1.1
Verbal and Numeric Reasoning (VNR)	0.3	0.6	1.7	0.4	0.0	1.3
Ovarian Cancer	0.3	0.4	0.7	0.7	0.2	0.9
Prostate Cancer	0.3	0.4	1.1	1.1	0.1	0.0
Lupus	0.3	0.5	1.6	1.2	0.1	0.1
Triglycerides	0.3	0.5	0.8	-0.8	-0.9	-0.2
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.5	-0.6	-0.7	0.1
Blood Platelet Count	0.3	3.8	7.2	2.7	0.5	-2.0
Waist Hip Ratio (WHR)	0.3	1.3	2.6	-1.6	1.0	0.4
Lung FVC	0.3	1.5	2.2	-0.5	-1.4	1.5
Chronotype (morning person)	0.3	0.8	1.3	-1.0	-1.1	-0.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.0	0.3	1.0	-0.1
Systolic blood pressure, automated reading	0.3	0.9	2.1	1.4	-0.0	0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.0	-0.0	0.1	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.0	-0.4	-0.4	1.0
Relative age voice broke	0.3	0.4	0.9	0.0	-1.0	0.5
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.3	0.5	-0.6	0.5
Had other major operations	0.3	0.4	1.0	0.3	1.0	-0.1
Forced vital capacity (FVC)	0.3	1.3	2.6	-0.2	-1.6	1.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.7	-0.8	0.6	-0.4
Medication: Ramipril	0.3	0.4	0.5	0.7	0.6	-0.4
Pulse rate	0.3	0.5	0.6	-0.7	-0.7	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.9	0.3	-0.1	-1.0
Blood clot in the leg (DVT)	0.3	0.4	0.8	0.9	0.0	0.7
Glaucoma (self-reported)	0.3	0.4	1.2	-1.1	0.1	-0.2
Qualifications: College or University degree	0.3	0.8	2.3	-1.5	0.2	0.3
Medication: Ibuprofen	0.3	0.4	0.6	0.8	0.8	0.0
Had major operations	0.3	0.4	1.0	0.4	-1.0	0.2
Age at last live birth	0.3	0.5	0.7	0.8	0.4	-0.8
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.7	-0.8	-0.1	-0.7
High cholesterol (Self-reported)	0.3	0.6	0.9	0.7	-0.5	0.9
Illnesses of father: High blood pressure	0.3	0.3	0.7	0.3	-0.8	-0.4
Age started oral contraceptive pill	0.3	0.4	0.6	0.8	0.2	0.6
Commuting to job workplace: Cycle	0.3	0.4	0.7	0.0	0.6	-0.8
Depressed Affect (Nagel 2018)	0.2	0.5	1.5	1.2	0.3	-0.2
Reaction Time	0.2	0.3	0.5	-0.7	-0.6	0.4
Blood White Count	0.2	1.3	3.3	0.6	1.8	-0.4
Heel T-Score	0.2	1.9	5.0	-0.8	2.2	-0.1
Lung FEV1/FVC ratio	0.2	0.8	1.1	-1.0	0.8	-0.9
Hand grip strength (left)	0.2	0.6	1.8	-1.3	-0.0	0.4
Angina	0.2	0.3	0.7	-0.2	-0.3	0.8
Supplements: Zinc	0.2	0.2	0.4	0.5	-0.6	0.1
Diabetes (mother)	0.2	0.3	0.8	-0.1	0.2	0.9
Hand grip strength (right)	0.2	0.5	1.4	-1.2	-0.4	0.2
Townsend deprivation index at recruitment	0.2	0.3	0.8	-0.9	-0.1	0.1
Current tobacco smoking	0.2	0.4	0.7	-0.5	0.8	0.4
Stomach or abdominal pain in last month	0.2	0.2	0.3	0.2	0.4	0.6
Impedance of leg (left)	0.2	1.0	2.7	-1.6	-0.2	0.3
Qualifications: None of the above	0.2	0.5	1.3	1.1	-0.3	-0.3
Medication: Simvastatin	0.2	0.3	0.4	-0.6	0.4	0.6
Fluid intelligence score	0.2	0.5	1.1	-1.0	0.6	0.4
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.2	-0.4	-1.1	0.6
Happiness	0.2	0.3	0.5	0.7	-0.4	0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.4	0.7	0.8	0.6	-0.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	0.9	-0.9	-0.0	-0.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.9	0.3	-0.5	-1.0
Gout (self-reported)	0.2	0.2	0.4	0.7	0.4	-0.3
Leg fat percentage (right)	0.2	0.8	2.0	-0.2	-0.6	1.4
Health satisfaction	0.2	0.3	0.4	0.6	0.5	0.5
Angina (self-reported)	0.2	0.3	0.8	0.2	-0.3	0.9
Knee pain experienced in last month	0.2	0.4	0.6	-0.7	-0.1	0.8
Illnesses of siblings: Diabetes	0.2	0.3	0.7	-0.9	0.2	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.9	-0.2	-0.0	-1.0
Mood swings	0.2	0.4	1.1	-0.1	-0.0	1.0
Back pain experienced in last month	0.2	0.3	0.6	0.3	-0.5	0.8
Smoking status: Current	0.2	0.4	0.9	-0.4	1.0	0.3
Number of self-reported non-cancer illnesses	0.2	0.3	0.7	-0.2	0.2	0.8
Medication: Bendroflumethiazide	0.2	0.2	0.6	0.8	0.4	0.1
Risk taking	0.2	0.3	0.6	0.7	0.5	0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.2	0.5	0.4	0.4
Alcohol drinker status: Previous	0.2	0.2	0.5	0.2	0.5	-0.7
Bipolar Disorder (2018)	0.1	0.2	0.6	-0.3	-0.8	-0.2
Major Depression (MDD)	0.1	0.2	0.4	0.2	-0.6	0.3
Age at First Birth	0.1	0.1	0.2	0.4	0.2	0.3
Bipolar Disorder (2011)	0.1	0.1	0.3	-0.3	0.6	-0.0
HDL Cholesterol	0.1	0.2	0.5	0.1	-0.0	-0.7
Blood Eosinophil Count	0.1	1.0	1.8	-0.7	0.8	-1.4
BMI	0.1	0.3	0.7	0.5	-0.8	0.2
Tanning	0.1	1.0	2.2	0.7	0.7	-1.5
Relative age of first facial hair	0.1	0.3	0.4	0.5	-0.7	0.5
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.3	0.6	0.1	0.4
Multivitamins +/- minerals	0.1	0.1	0.2	0.0	-0.4	-0.3
Medication: Atenolol	0.1	0.1	0.3	0.0	0.5	-0.1
Sitting height	0.1	1.0	1.6	-0.5	-1.2	1.1
Body mass index (BMI)	0.1	0.6	1.1	0.7	-0.3	1.0
Hearing difficulty/problems with background noise	0.1	0.2	0.4	-0.6	-0.4	-0.2
Impedance of arm (right)	0.1	0.5	1.0	-1.0	0.3	-0.7
Trunk fat-free mass	0.1	0.6	1.2	0.4	1.1	-0.7
Hip circumference	0.1	0.3	0.8	0.9	-0.2	-0.2
Asthma	0.1	0.3	0.4	0.5	-0.5	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.4	0.1	0.3	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	0.7	-0.9	0.2	-0.1
Trunk predicted mass	0.1	0.7	1.3	0.4	1.1	-0.8
Standing height	0.1	1.4	2.6	-0.5	1.2	-1.6
Length of working week for main job	0.1	0.1	0.1	-0.3	-0.0	0.4
Peak expiratory flow (PEF)	0.1	0.1	0.4	-0.1	-0.6	-0.1
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	0.5	0.3	-0.0
Forced vital capacity (FVC), Best measure	0.1	0.2	0.3	-0.4	-0.5	0.5
Number of full brothers	0.1	0.2	0.3	0.1	-0.4	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.3	-0.4	-0.2	-0.5
Mean time to correctly identify matches	0.1	0.2	0.3	-0.6	0.0	0.3
Heart disease (mother)	0.1	0.1	0.1	-0.3	0.4	0.2
Leg fat mass (right)	0.1	0.5	1.1	-0.0	-0.6	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.1	-0.3	-0.3	-0.2
Whole body fat-free mass	0.1	0.5	0.8	0.3	0.9	-0.8
Leg fat-free mass (right)	0.1	0.8	1.3	0.5	0.8	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.2	-0.2	-0.4	-0.5
Asthma (self-reported)	0.1	0.3	0.5	0.2	-0.6	0.7
Osteoporosis (self-reported)	0.1	0.1	0.2	-0.5	-0.3	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.6	-0.1	0.7	-0.1
Whole body water mass	0.1	0.6	0.9	0.4	1.0	-0.8
Leg predicted mass (right)	0.1	0.8	1.4	0.5	0.8	-1.2
Average weekly champagne plus white wine intake	0.1	0.1	0.2	0.1	-0.3	-0.4
Wears glasses or contact lenses	0.1	0.1	0.1	-0.2	0.1	0.4
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	0.1	-0.5	-0.2
Basal metabolic rate	0.1	0.4	0.6	0.4	0.8	-0.7
Leg fat percentage (left)	0.1	0.3	0.7	0.2	-0.3	0.8
Impedance of whole body	0.1	0.7	1.8	-1.3	-0.4	0.2
Leg fat mass (left)	0.1	0.3	0.6	0.2	-0.4	0.7
Arm predicted mass (left)	0.1	0.3	0.3	0.5	0.5	-0.6
Height	0.0	0.4	0.8	-0.4	0.5	-0.9
Allergy or Eczema	0.0	0.1	0.2	-0.1	-0.4	0.3
Hair Pigment	0.0	0.4	0.8	0.6	0.9	-0.3
Hearing difficulty/problems: Yes	0.0	0.0	0.1	0.2	-0.1	-0.1
Leg fat-free mass (left)	0.0	0.2	0.3	0.3	0.4	-0.5
Trunk fat percentage	0.0	0.1	0.2	-0.2	-0.5	0.3
Leg predicted mass (left)	0.0	0.2	0.3	0.3	0.4	-0.6
Trunk fat mass	0.0	0.0	0.0	-0.2	-0.1	0.1
Waist circumference	0.0	0.2	0.4	0.1	0.3	0.6
Allergy	0.0	0.1	0.2	-0.2	-0.4	-0.3
Weight	0.0	0.1	0.2	0.5	0.2	0.3
Arm fat percentage (right)	0.0	0.1	0.1	0.2	-0.1	0.4
Impedance of arm (left)	0.0	0.2	0.4	-0.7	0.1	-0.4
Arm fat mass (right)	0.0	0.1	0.1	0.3	0.2	0.3
Birth weight	0.0	0.1	0.1	0.2	0.3	-0.2
Body fat percentage	0.0	0.1	0.3	-0.0	-0.4	0.5
Arm fat-free mass (right)	0.0	0.2	0.3	0.4	0.6	-0.4
Whole body fat mass	0.0	0.0	0.0	-0.1	-0.1	0.2
Arm predicted mass (right)	0.0	0.1	0.2	0.1	0.5	-0.3
Arm fat percentage (left)	0.0	0.1	0.3	0.2	-0.3	0.5
Qualifications: nursing, teaching	0.0	0.0	0.0	0.1	-0.2	0.0
Arm fat mass (left)	0.0	0.1	0.2	0.2	-0.1	0.4
Arm fat-free mass (left)	0.0	0.2	0.3	0.6	0.5	-0.4

Hub : Genes

GJA5

Models

Trait associations