Best TWAS P=7.84e-13 · Best GWAS P=1.14e-16 conditioned to 1.49e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pancreas | MIPOL1 | 0.25 | 0.19 | enet | 52 | 0.17 | 9.7e-08 | -7.2 | 6.7 | 2.4e-11 | -0.79 | 0.06 | 0.93 | FALSE |
| 2 | GTEx | Thyroid | MIPOL1 | 0.11 | 0.00 | lasso | 2 | 0.01 | 1.2e-01 | -6.5 | -6.2 | 7.6e-10 | 0.67 | 0.17 | 0.14 | FALSE |
| 3 | The Cancer Genome Atlas | Rectum Adenocarcinoma | FOXA1 | 0.11 | 0.03 | blup | 41 | 0.03 | 7.6e-02 | -4.5 | -5.9 | 4.6e-09 | 0.79 | 0.01 | 0.67 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MIPOL1 | 0.05 | 0.07 | lasso | 2 | 0.07 | 4.6e-07 | -7.2 | -7.2 | 7.8e-13 | 0.92 | 0.33 | 0.67 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC25A21 | 0.15 | 0.12 | blup | 353 | 0.11 | 5.2e-11 | -7.1 | -5.9 | 3.1e-09 | 0.72 | 0.05 | 0.95 | FALSE |