TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood Red Count
:
←
→
chr14:36,900,126-38,715,739
Best TWAS P=7.84e-13 · Best GWAS P=1.14e-16 conditioned to 1.49e-05
37M
37.5M
38M
38.5M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Thyroid Carcinoma
MIPOL1
0.05
0.07
lasso
2
0.07
4.6e-07
-7.2
-7.2
7.8e-13
0.92
0.33
0.67
TRUE
1
GTEx
Pancreas
MIPOL1
0.25
0.19
enet
52
0.17
9.7e-08
-7.2
6.7
2.4e-11
-0.79
0.06
0.93
FALSE
2
GTEx
Thyroid
MIPOL1
0.11
0.00
lasso
2
0.01
1.2e-01
-6.5
-6.2
7.6e-10
0.67
0.17
0.14
FALSE
5
The Cancer Genome Atlas
Thyroid Carcinoma
SLC25A21
0.15
0.12
blup
353
0.11
5.2e-11
-7.1
-5.9
3.1e-09
0.72
0.05
0.95
FALSE
3
The Cancer Genome Atlas
Rectum Adenocarcinoma
FOXA1
0.11
0.03
blup
41
0.03
7.6e-02
-4.5
-5.9
4.6e-09
0.79
0.01
0.67
FALSE