Hub : Genes

MIPOL1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0650	0.0240	5.0e-04	0.046	0.013	0.040	0.033	0.041	2.6e-06	9.5e-03	1.1e-05	0.00006	7.9e-06
2	GTEx	Adipose Subcutaneous	0.1360	0.0430	4.4e-05	0.003	NA	0.058	NA	0.035	1.8e-01	NA	1.7e-05	NA	7.1e-04
3	GTEx	Esophagus Mucosa	0.1570	0.0680	2.2e-03	0.023	NA	0.053	NA	0.048	1.1e-02	NA	1.9e-04	NA	3.6e-04
4	GTEx	Heart Atrial Appendage	0.2170	0.0930	5.4e-03	-0.006	NA	0.043	NA	0.000	7.8e-01	NA	5.0e-03	NA	3.1e-01
5	GTEx	Pancreas	0.2530	0.0670	8.5e-07	0.190	NA	0.172	NA	0.168	1.8e-08	NA	9.7e-08	NA	1.4e-07
6	GTEx	Thyroid	0.1080	0.0410	1.4e-03	0.003	NA	0.002	NA	0.005	1.7e-01	NA	2.1e-01	NA	1.2e-01
7	NTR	Blood	0.0208	0.0099	7.7e-03	0.001	0.003	0.000	0.005	0.001	1.8e-01	3.4e-02	3.7e-01	0.00590	1.0e-01
8	TCGA	Thyroid Carcinoma	0.0500	0.0230	3.0e-06	0.072	0.059	0.056	NA	0.067	1.7e-07	2.0e-06	3.9e-06	NA	4.7e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.7	2.7	6.2	-0.1	-0.9	-0.8	-2.5	2.4	-1.7	-0.8	-2.2
Bipolar Disorder or Schizophrenia	0.4	1.0	3.4	-0.4	-0.3	-0.5	-0.5	1.8	-1.4	-0.2	-1.3
Depressed Affect (Nagel 2018)	0.6	1.3	4.5	-0.7	0.0	0.1	-1.6	1.6	-2.1	0.2	-0.4
Depression (Nagel 2018)	2.1	3.1	7.2	0.0	-1.4	-1.4	-2.4	2.1	-2.7	0.6	-1.9
Intelligence (Savage-Jansen 2018)	1.6	5.0	9.6	-0.2	-2.1	-2.3	-2.7	2.2	-1.5	2.6	-3.1
Neuroticism (Nagel 2018)	0.3	0.6	4.2	0.2	0.3	-0.1	-2.0	0.3	-0.6	-0.1	0.3
Schizophrenia (2018)	0.1	0.3	1.1	-0.4	0.4	-0.0	1.0	0.7	-0.4	0.3	0.1
Schizophrenia vs Biploar Disorder	0.5	0.6	1.8	0.0	0.2	-0.2	1.1	-0.8	-0.9	1.4	0.9
Worry (Nagel 2018)	0.3	0.6	1.5	1.2	0.6	-0.3	-0.3	-0.3	0.6	-1.1	0.9
Alzheimer’s Disease (in mother)	0.9	1.0	3.4	0.9	0.4	-1.9	-1.5	0.6	-0.9	-0.7	0.2
Alzheimer’s Disease (in father)	1.0	1.1	3.0	0.4	1.0	0.2	1.4	-0.9	1.7	-0.9	0.9
Alzheimer’s Disease (including proxy)	0.8	1.1	2.9	1.2	0.7	-1.5	-0.9	-0.2	0.0	-1.7	0.9
Crohns Disease (2017)	0.7	1.6	4.4	0.8	-1.0	-1.2	0.6	2.1	-1.3	0.5	-1.7
Irritable Bowel Disease (IBD)	0.4	1.0	2.1	1.1	-1.0	-1.3	0.2	1.4	-0.6	-0.3	-1.1
Ulcerative Colitis (UC)	0.2	0.4	1.3	0.8	-0.0	-0.5	-0.0	-0.3	0.8	-1.2	0.3
Major Depression (MDD)	0.8	1.0	1.9	-0.6	-1.3	-1.0	-0.8	1.4	-0.9	0.2	-1.3
Reaction Time	1.3	2.5	6.3	1.2	0.8	-0.2	2.5	-2.3	1.8	0.5	1.7
Verbal and Numeric Reasoning (VNR)	0.9	2.2	7.6	-0.7	-1.0	-0.4	-1.8	1.4	-0.4	2.7	-1.8
Breast Cancer	0.3	0.7	2.2	-1.5	0.9	0.9	-0.0	-0.3	0.3	1.2	-0.3
Ovarian Cancer	0.8	1.1	1.9	1.0	-1.2	-1.1	-0.7	1.1	-0.9	-1.4	-0.9
Prostate Cancer	5.7	8.0	18.9	1.1	-2.7	-3.0	-2.7	4.3	-2.4	-1.4	-3.5
Age at First Birth	0.2	0.3	1.5	-0.4	0.1	-0.8	0.4	0.5	0.2	1.2	-0.2
Bipolar Disorder (2011)	1.0	0.9	2.4	-1.6	1.1	0.8	0.0	0.1	-1.5	1.0	-0.2
Body Mass Index (BMI) (2010)	0.6	0.9	3.0	0.5	-0.2	-0.9	-0.9	-0.3	-1.4	1.7	-0.4
Coronary Artery Disease (CAD)	0.9	1.1	2.8	-1.6	1.0	0.8	0.8	-1.0	0.2	1.7	0.6
Crohns Disease (2012)	0.2	0.3	1.0	0.1	-0.2	-1.0	0.1	0.3	-0.8	0.6	-0.2
Mean Putamen Volume	0.7	0.8	3.3	-0.3	0.9	1.2	1.8	1.0	0.2	-0.2	-0.2
Fasting Glucose	0.4	0.5	1.9	0.6	0.4	0.0	-1.4	0.1	-0.2	-1.1	0.1
HbA1C	1.0	1.1	3.6	1.6	-1.4	-1.9	-0.2	0.3	-0.3	0.3	-0.4
HDL Cholesterol	1.1	1.8	6.4	-2.3	1.2	2.5	-0.8	0.5	0.3	0.6	-0.1
LDL Cholesterol	0.2	0.3	0.7	0.8	0.0	0.1	0.4	-0.5	0.5	-0.9	0.7
Lupus	0.8	1.2	3.7	1.9	-1.2	-0.9	0.8	0.0	1.6	-0.2	-0.2
Neuroticism (2016)	0.9	1.4	4.0	-0.2	-0.8	-1.0	-1.5	2.0	-0.5	-1.0	-1.3
Primary Biliary Cirrhosis	0.3	0.4	1.6	0.3	-0.2	-0.1	-0.3	-1.3	0.7	-0.7	0.6
Rheumatoid Arthritis	2.3	3.2	7.4	-1.2	1.1	1.9	1.0	-1.5	2.6	-1.5	2.7
Schizophrenia (2014)	0.2	0.5	2.1	-0.1	0.0	0.1	1.4	0.9	-0.8	-0.1	-0.2
Triglycerides	0.3	0.5	1.8	1.3	-0.3	-0.8	-0.3	-1.0	0.2	-0.5	0.7
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.1	0.0	0.4	1.0	0.7	-0.3	0.6	0.4	0.3
Ulcerative Colitis	0.7	1.0	3.8	1.2	0.6	-1.4	-0.7	-0.0	0.5	-2.0	0.2
Blood Eosinophil Count	1.0	8.1	26.4	0.1	2.2	1.7	0.8	-3.7	3.7	-1.6	5.1
Blood Platelet Count	0.0	0.4	2.1	0.3	-1.4	-0.5	-0.3	-0.2	0.1	-0.8	0.3
Blood Red Count	2.3	22.0	51.3	-1.8	-2.7	-3.1	-4.2	6.7	-6.2	2.0	-7.2
Blood White Count	0.0	0.3	1.0	-0.7	-0.6	0.3	-0.5	0.1	1.0	-0.7	-0.1
Heel T-Score	0.1	1.2	7.8	-0.5	-0.9	-0.1	-2.8	0.3	0.0	0.6	-0.2
BMI	0.5	2.6	4.7	-2.2	2.2	2.1	-1.1	-1.0	0.3	1.4	1.7
Height	0.1	2.6	6.2	0.0	-1.4	-0.7	-1.1	2.2	-2.2	1.0	-2.5
Waist Hip Ratio (WHR)	0.9	4.0	13.0	-0.4	-1.5	-1.7	-0.4	3.6	-1.6	0.7	-3.2
Systolic Blood Pressure	0.4	2.2	6.3	-2.5	1.5	2.2	-0.1	-0.2	0.4	2.0	0.8
Smoking Status	0.6	1.5	3.9	-1.3	1.1	0.8	-0.1	2.0	-0.9	1.7	-0.8
Allergy or Eczema	2.4	6.3	11.7	-3.4	2.8	3.2	1.8	-0.6	2.3	2.7	2.1
Cardiovascular Disease	1.4	4.6	8.8	-0.4	-2.5	-1.4	-2.0	2.9	-3.0	0.4	-2.7
Hypothyroidism (self reported)	0.3	0.6	2.5	1.6	-0.7	-0.8	-0.9	0.5	-0.3	-0.6	0.1
Respiratory disease	1.8	4.0	4.9	-2.2	2.2	2.0	1.4	-2.1	1.5	2.1	2.2
Type 2 Diabetes (T2D) (2018)	0.8	1.5	5.1	-0.6	0.0	0.1	-2.3	1.9	-1.1	-0.2	-1.2
Lung FEV1/FVC ratio	0.3	1.4	5.1	1.1	-1.1	0.0	-1.8	-0.3	0.4	-2.3	0.2
Lung FVC	3.0	15.4	31.8	0.7	-4.0	-4.0	-4.3	4.6	-4.4	-0.5	-5.6
Neuroticism	0.4	1.0	5.8	-0.0	0.4	0.3	-2.4	0.3	0.4	-1.0	0.7
Chronotype (morning person)	0.8	1.9	5.4	2.3	-0.8	-1.6	-1.4	1.1	-0.5	-0.9	-1.4
Hair Pigment	0.1	2.2	5.6	0.5	1.1	0.3	2.0	-2.4	1.9	0.0	1.8
Tanning	0.1	0.7	2.3	-1.5	-0.1	0.1	1.3	0.2	0.0	1.3	-0.2
Hand grip strength (left)	0.6	1.6	3.1	1.4	0.5	1.3	-0.7	-1.8	-0.1	-1.7	1.5
Number of treatments/medications taken	0.4	0.8	2.4	-0.8	0.4	0.7	-1.3	1.6	-0.8	-0.2	-0.4
Average weekly spirits intake	0.3	0.3	1.6	0.0	-0.7	-0.2	0.1	0.4	0.5	-1.3	0.4
Sensitivity / hurt feelings	0.4	0.7	3.6	0.2	-0.4	-0.4	-1.9	0.9	-0.5	0.5	-0.7
Frequency of depressed mood in last 2 weeks	2.5	3.4	7.4	-0.5	-1.2	-1.0	-2.4	2.7	-2.6	1.1	-1.9
Hearing difficulty/problems: Yes	0.3	0.5	2.1	0.1	0.1	1.1	-1.5	-0.6	0.4	-0.3	0.1
Relative age of first facial hair	0.6	1.2	3.9	-0.6	-1.1	-1.0	-0.5	2.0	-1.0	-0.4	-1.5
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	5.6	-0.1	-0.2	-0.0	0.1	1.8	-2.0	1.1	-2.4
Ever used hormone-replacement therapy (HRT)	1.8	2.3	8.4	0.9	-1.4	-1.9	-0.1	1.7	-1.0	-0.2	-2.9
Ever had hysterectomy (womb removed)	2.0	2.3	4.3	0.6	-1.2	-1.4	-1.9	1.7	-1.8	0.4	-2.1
Systolic blood pressure, automated reading	0.5	1.3	3.4	-1.7	1.9	0.9	-0.6	0.7	0.5	1.5	0.0
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.5	1.0	-1.2	-0.2	0.2	1.1	-0.7	-0.0	-0.8
Angina	0.6	0.8	3.5	-0.4	0.6	1.9	0.1	-0.8	0.5	-0.6	1.1
Medication for hormone replacement therapy	2.0	2.2	4.3	1.5	-0.9	-2.1	0.8	1.4	-1.8	0.7	-2.1
Vitamin and mineral supplements	2.3	3.2	5.8	-1.0	2.1	2.3	0.9	-1.6	2.4	0.2	2.3
Supplements: Zinc	1.5	1.6	4.4	-2.0	0.7	1.5	2.1	-0.2	0.7	1.0	0.7
Medication: Co-codamol	1.5	1.7	3.8	0.4	-1.9	-1.7	0.2	1.4	-1.0	0.8	-1.9
Medication: Metformin	1.8	2.6	8.4	-0.1	-1.4	-0.4	-0.4	2.9	-2.7	0.3	-1.7
Diabetes (father)	0.7	0.8	3.7	0.7	-0.7	-0.8	1.9	0.3	-0.3	1.0	-0.2
Diabetes (mother)	0.1	0.2	0.5	0.1	-0.7	-0.3	-0.7	-0.0	-0.5	-0.2	0.2
Severe depression (siblings)	0.6	0.6	1.2	0.5	-1.1	-1.1	-0.8	0.8	-0.1	-1.0	-0.4
Pack years adult smoking proportion	0.5	0.8	1.9	-0.7	0.7	1.2	-0.6	-1.2	0.3	-0.3	1.4
Impedance of leg (right)	0.1	0.3	1.0	1.0	-0.6	-1.0	-0.1	0.2	-0.2	-0.2	-0.4
Leg fat-free mass (left)	0.2	0.9	1.8	-1.2	0.2	1.0	-1.3	0.1	-1.0	1.3	-0.2
Trunk fat percentage	0.2	1.0	2.0	-1.4	0.9	0.7	-1.3	0.2	0.7	1.3	0.7
Hand grip strength (right)	0.5	1.4	3.7	0.7	-0.2	1.5	0.3	-1.8	0.9	-0.7	1.9
Townsend deprivation index at recruitment	0.5	0.7	2.0	-0.7	-0.1	0.8	-1.4	-0.1	-1.4	-0.5	-0.0
Current tobacco smoking	0.5	0.8	2.3	-0.5	-0.1	0.2	0.7	1.1	-1.5	1.2	-0.6
Average weekly fortified wine intake	0.6	0.7	1.7	-0.9	0.9	1.3	-0.4	0.7	-0.5	-1.2	-0.5
Maternal smoking around birth	0.6	0.8	2.1	-0.4	-1.4	-0.5	-0.6	1.4	-0.1	0.7	-1.2
Fed-up feelings	1.0	1.8	4.4	-2.1	0.4	1.4	-1.4	1.7	-1.7	0.7	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	3.1	-0.2	-0.8	-0.5	0.1	1.5	-1.3	0.5	-1.8
Relative age voice broke	1.3	1.9	3.8	1.1	-1.5	-1.4	1.6	1.1	-2.0	-0.3	-1.5
Taking other prescription medications	1.0	1.5	5.2	-2.3	0.6	2.1	-0.4	1.1	-0.1	0.5	-0.1
Age when periods started (menarche)	0.5	1.3	3.5	0.5	0.6	-0.0	1.0	-1.9	1.9	0.3	1.2
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	4.6	-1.1	-0.3	-0.5	-1.7	1.6	-1.0	-0.8	-2.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.0	-0.4	0.6	0.7	-0.8	0.1	1.0	-0.1	0.3
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	2.5	-1.1	0.0	0.4	-1.6	-0.4	-0.2	1.2	0.1
Qualifications: CSEs or equivalent	0.5	0.7	3.0	-0.2	-1.7	-0.1	-0.3	0.8	-0.4	0.2	-1.1
Serious illness, injury or assault to yourself	3.9	4.7	8.2	-2.6	-1.6	0.3	-2.2	2.9	-2.1	1.6	-2.9
High blood pressure	0.8	2.1	4.6	-0.7	-0.9	-0.4	-2.1	1.8	-2.0	1.1	-1.7
Hayfever, allergic rhinitis or eczema	1.9	4.1	7.5	-2.7	2.3	2.7	1.4	-0.8	1.3	2.5	1.6
Multivitamins +/- minerals	1.8	2.2	5.6	0.6	-1.3	-1.7	-0.4	1.6	-2.4	-0.5	-2.1
Stomach or abdominal pain in last month	0.4	0.5	1.9	0.9	-0.6	-0.3	-1.4	-0.1	-0.8	-0.6	0.1
Supplements: Glucosamine	1.9	2.5	7.2	-0.6	-0.9	-1.1	-1.9	2.4	-1.1	-0.3	-2.7
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.8	0.7	-0.0	-0.5	-1.4	0.1	-0.7	0.6	0.2
Medication: Atenolol	0.3	0.4	2.1	0.4	-0.3	-0.1	0.0	0.6	-0.4	-1.5	-0.4
Medication: Levothyroxine sodium	0.1	0.2	0.4	-0.6	-0.1	0.7	-0.2	0.4	0.5	0.4	-0.1
Sitting height	0.8	5.8	14.3	1.0	-2.2	-1.8	-1.1	2.7	-3.8	1.4	-3.5
Chronic bronchitis/emphysema (father)	3.6	4.3	6.8	0.8	-2.3	-2.6	-2.2	2.6	-1.9	-0.2	-2.5
High blood pressure (mother)	1.1	1.6	6.3	-2.5	0.0	0.8	0.2	0.6	-0.2	2.2	0.1
Body mass index (BMI)	0.5	2.0	3.7	-1.9	1.6	1.9	-1.5	-0.6	0.5	1.0	1.4
Impedance of leg (left)	0.1	0.3	0.9	0.9	-0.3	-0.7	0.6	-0.2	0.5	0.3	0.1
Leg predicted mass (left)	0.2	0.9	1.9	-1.3	0.2	1.0	-1.3	0.1	-1.1	1.4	-0.3
Trunk fat mass	0.2	1.1	2.5	-1.5	0.9	0.8	-1.3	0.4	0.3	1.6	0.5
Waist circumference	0.2	0.9	2.9	-1.7	0.9	0.9	-0.7	0.3	0.1	1.4	0.2
Number of incorrect matches in round	1.4	2.3	6.5	0.6	2.0	1.1	0.7	-2.1	1.2	-0.2	2.6
Past tobacco smoking	0.4	0.7	3.3	0.6	-1.8	-0.9	0.5	-0.2	-0.3	-0.6	-0.4
Alcohol usually taken with meals	1.4	2.3	6.1	0.4	-1.8	-2.5	-0.8	1.9	-0.8	-0.5	-1.9
Nervous feelings	0.3	0.5	1.3	0.7	0.6	0.5	0.2	-0.8	0.8	-0.4	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.3	0.0	0.1	-0.0	-0.5	0.3	-0.3	-0.5	0.3
Hearing difficulty/problems with background noise	0.2	0.3	1.0	0.5	-0.5	-0.4	-1.0	0.0	-0.5	0.1	-0.0
Hair/balding pattern: Pattern 2	1.2	1.6	4.1	0.4	-1.7	-1.0	0.1	1.0	-1.7	0.5	-2.0
Had menopause	0.4	0.6	1.5	-0.0	0.0	-0.6	-0.6	1.0	0.7	-0.9	-1.2
Had other major operations	0.8	1.0	2.8	-0.2	0.2	0.6	-1.5	1.7	-0.2	-1.4	-0.8
Forced vital capacity (FVC)	2.7	10.4	25.2	1.0	-3.6	-2.9	-2.0	4.1	-3.8	-1.2	-5.0
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	4.3	-0.8	0.3	0.6	-2.1	0.6	0.8	0.1	0.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.3	-0.5	-0.0	-0.7	-0.6	0.3	-1.1	0.9	-0.2
Qualifications: None of the above	0.4	0.9	3.3	0.9	-0.5	-1.8	-0.6	0.6	-1.1	-0.9	-0.5
Financial difficulties in last 2 years	1.1	1.5	3.2	-0.9	-1.2	0.8	-0.6	1.5	-1.8	1.1	-1.6
Mouth/teeth dental problems	0.3	0.5	2.5	-0.6	-1.6	-0.1	-0.4	0.5	0.3	0.5	-0.8
Heart attack	0.7	0.9	1.9	-0.6	0.7	1.3	0.8	0.4	1.0	-1.4	1.0
Allergy	2.5	5.6	10.3	2.8	-2.8	-3.2	-1.9	1.4	-2.1	-1.8	-2.4
Pain all over the body in last month	2.9	3.1	9.9	0.8	-1.3	-1.8	-0.9	1.5	-2.5	0.6	-3.1
Diabetes (self-reported)	1.3	2.0	5.9	-0.1	-0.1	-1.0	-2.4	2.4	-0.8	-0.5	-1.4
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	4.2	-1.6	0.6	1.1	1.4	-1.2	0.5	2.0	0.8
Medication: Ramipril	0.9	1.2	5.8	0.1	-0.5	-0.5	-2.4	1.3	-0.2	-1.2	-0.0
Medication: Simvastatin	0.7	1.0	3.6	0.5	0.2	-0.2	-1.9	0.8	-0.5	-1.8	-0.3
Fluid intelligence score	0.9	1.9	12.2	-1.1	0.4	0.3	-1.2	-0.2	-0.3	3.5	-0.3
Illnesses of siblings	0.3	0.4	0.9	0.8	-0.9	0.2	0.8	0.4	-0.4	-0.5	-0.4
Neuroticism score	0.4	0.7	2.4	-0.1	0.9	0.9	-1.0	-0.8	0.3	0.1	1.5
Weight	0.3	1.3	2.8	-1.7	1.0	1.4	-1.6	0.1	-0.3	1.3	0.4
Impedance of arm (right)	0.2	0.9	2.4	1.1	-0.7	-1.6	-0.1	0.8	-0.1	-1.2	-0.8
Arm fat percentage (right)	0.3	1.1	2.7	-1.4	1.3	0.8	-1.6	-0.1	0.5	0.9	1.0
Trunk fat-free mass	0.1	0.8	1.9	-0.6	-0.3	0.7	-1.2	-0.0	-1.4	1.3	-0.5
Hip circumference	0.3	1.3	2.4	-1.1	1.5	1.5	-0.5	-1.0	1.0	0.3	1.6
Time employed in main current job	0.8	0.9	2.5	1.5	0.8	-1.1	-0.7	-0.1	0.0	-1.6	0.2
Alcohol intake versus 10 years previously	0.4	0.6	1.7	-0.8	0.3	1.2	1.3	-0.2	0.5	0.0	0.8
Father’s age at death	1.2	1.5	5.5	0.2	0.8	-0.6	-2.3	-1.2	-0.5	2.0	0.0
Worrier / anxious feelings	0.6	1.2	3.4	0.4	1.8	0.6	-0.6	-1.1	1.2	-0.9	1.2
Frequency of tiredness / lethargy in last 2 weeks	3.5	5.7	11.6	0.2	-2.3	-2.1	-2.6	2.7	-3.4	0.5	-3.2
Falls in the last year	0.9	1.2	2.2	-1.4	0.0	1.2	-0.5	1.2	-1.5	1.4	-0.2
Hair/balding pattern: Pattern 3	0.2	0.4	1.0	-0.2	0.7	-0.1	-0.8	-0.4	0.7	0.0	1.0
Number of live births	0.6	0.9	2.5	-0.2	-0.8	-0.5	0.7	1.0	-0.2	1.6	-1.5
Forced expiratory volume in 1-second (FEV1)	3.6	12.1	24.9	1.7	-4.3	-3.1	-2.9	3.9	-4.0	-1.6	-5.0
Pulse rate	0.1	0.1	0.4	-0.5	0.0	0.1	0.7	0.5	0.3	-0.0	-0.3
Happiness	0.8	0.9	3.4	-0.2	1.0	1.8	0.3	-1.0	0.7	0.2	1.2
Noisy workplace	0.5	0.6	2.4	-0.6	-0.3	0.3	1.5	0.8	-0.7	0.9	-0.5
Qualifications: A levels/AS levels or equivalent	0.7	1.5	3.7	-1.6	-0.2	-0.1	-1.9	1.2	-0.5	0.7	-1.7
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.0	9.6	-0.4	-0.3	-0.6	-1.5	0.5	-3.1	1.4	-1.3
Mouth/teeth dental problems: Dentures	0.6	1.0	3.1	0.6	1.5	0.1	0.7	0.3	0.5	-1.8	1.0
Asthma	1.9	3.7	6.9	-1.9	2.6	2.2	1.5	-1.5	1.6	1.5	2.3
Medication: Ibuprofen (e.g. Nurofen)	3.6	4.6	7.9	0.5	-2.6	-2.0	-1.6	2.8	-2.8	-0.4	-2.7
Medication: Cholesterol lowering	0.5	0.7	1.7	-1.0	0.9	0.8	-1.3	1.2	0.2	-0.5	0.4
Depression (self-reported)	0.8	1.0	2.6	-0.7	-1.6	-0.6	-0.9	1.1	-0.7	-0.3	-1.3
Medication: Lansoprazole	0.4	0.5	1.1	0.8	0.6	0.3	-0.5	-0.7	0.5	-1.0	0.8
Prospective memory result	0.2	0.3	1.3	-0.4	-0.0	0.2	0.9	-0.2	1.1	-0.1	0.4
Lung cancer (father)	0.5	0.6	2.2	-0.5	1.5	0.7	0.5	0.2	1.1	-0.1	0.3
Illnesses of mother	0.7	0.9	4.8	1.1	-0.0	-0.0	2.2	-0.7	-0.6	0.5	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	2.7	8.7	18.3	0.9	-3.7	-2.2	-2.8	3.5	-3.3	-1.4	-4.3
Pulse wave Arterial Stiffness index	1.3	1.5	3.0	0.1	1.2	-0.5	1.7	-1.7	0.4	1.6	1.2
Impedance of arm (left)	0.2	0.8	3.1	1.2	-0.8	-1.8	-0.0	0.4	-0.3	-0.6	-0.7
Arm fat mass (right)	0.2	1.0	2.7	-1.4	1.0	1.0	-1.6	0.2	0.2	0.9	0.5
Trunk predicted mass	0.1	0.8	2.2	-0.6	-0.4	0.6	-1.3	0.0	-1.5	1.3	-0.5
Standing height	0.2	1.6	4.1	0.6	-1.5	-0.9	-0.6	1.2	-1.7	0.9	-2.0
Length of working week for main job	0.9	1.0	3.5	-0.5	-0.7	0.5	0.1	0.4	-1.5	1.9	-1.1
Exposure to tobacco smoke at home	0.2	0.2	1.2	-0.3	0.2	0.3	-1.1	0.5	-0.0	-0.2	-0.0
Breastfed as a baby	2.0	2.5	9.5	0.2	1.2	0.4	0.5	-1.9	3.1	-1.2	1.8
Tense / ‘highly strung’	0.2	0.3	1.0	0.7	0.3	0.2	-0.1	-0.1	0.5	-1.0	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.5	4.9	1.3	-1.8	-1.8	-2.2	2.2	-2.0	-1.7	-1.7
Hair/balding pattern: Pattern 4	2.1	5.2	12.4	1.1	2.0	0.9	-0.6	-3.1	3.2	-1.6	3.5
Birth weight of first child	1.0	1.9	6.4	0.3	0.2	-1.2	-2.5	1.9	-1.0	-0.6	-1.4
Peak expiratory flow (PEF)	0.7	1.5	3.6	1.3	-1.1	-0.3	-1.5	1.0	-0.6	-1.9	-1.4
Pulse wave reflection index	0.5	0.7	1.9	0.8	-0.9	-1.4	-0.2	-0.5	-1.0	0.6	-0.4
Ever highly irritable/argumentative for 2 days	0.7	0.9	2.0	1.3	0.5	-0.6	-0.4	-1.3	0.5	-0.7	1.4
Loud music exposure frequency	2.0	2.2	8.5	0.0	0.7	0.7	2.9	-1.3	1.3	1.6	1.4
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	4.6	-2.1	1.3	1.0	-1.4	-0.3	0.9	2.2	-0.5
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	4.8	1.5	0.3	-1.0	-0.3	-2.2	-0.2	0.7	1.4
Blood clot in the leg (DVT)	2.3	3.0	8.2	0.6	1.1	1.1	1.4	-1.9	2.9	-1.4	2.4
Medication: Paracetamol	1.9	3.2	11.4	-1.7	-0.0	0.1	-1.4	1.5	-3.4	2.1	-1.7
Headache pain in last month	0.7	1.3	4.2	-0.1	-1.1	-0.7	-0.3	1.1	-2.1	0.7	-1.6
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.2	0.7	-0.9	-0.9	1.5	-0.4	-0.4	0.6	-0.8
Glaucoma (self-reported)	0.6	0.7	2.2	-1.4	0.4	0.5	0.5	0.4	-0.7	1.5	-0.4
Gout (self-reported)	0.1	0.2	0.5	-0.0	0.0	0.2	-0.7	0.2	0.4	-0.5	0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.7	0.8	-0.5	-0.8	-0.8	0.7	0.2	-0.2	-0.2
Medication: Amlodipine	0.1	0.1	0.3	-0.4	-0.0	0.5	0.3	0.0	0.4	0.0	-0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.7	-0.8	-0.3	-0.5	0.1	-0.3	-0.1	0.9	0.6
Birth weight	0.8	1.7	4.0	0.6	-1.1	-1.4	-0.1	1.5	-1.3	2.0	-1.5
Chronic bronchitis/emphysema (mother)	2.3	2.6	8.8	-1.4	-1.1	0.7	-0.2	3.0	-1.9	-0.5	-2.1
High blood pressure (siblings)	0.5	0.7	3.1	0.9	0.2	-0.8	-1.8	0.3	-0.7	0.4	-0.4
Forced vital capacity (FVC), Best measure	2.5	9.2	21.1	0.5	-3.5	-2.5	-2.5	3.7	-3.5	-1.1	-4.6
Body fat percentage	0.3	1.3	2.4	-1.5	1.3	0.8	-1.5	0.0	0.8	1.3	1.0
Leg fat percentage (right)	0.7	2.4	4.2	-1.7	2.1	1.5	-1.8	-0.8	1.2	1.3	1.7
Arm fat-free mass (right)	0.1	0.6	2.2	-0.9	-0.1	0.9	-0.8	0.0	-0.7	1.5	-0.2
Exposure to tobacco smoke outside home	0.4	0.6	1.2	-0.8	1.1	1.1	1.1	0.3	0.1	-0.0	0.4
Comparative body size at age 10	0.6	1.7	4.2	-2.0	-0.0	0.8	-0.2	1.6	-0.6	2.0	-1.4
Number of full brothers	0.6	0.8	2.8	-0.3	-1.1	-0.1	0.4	0.3	-1.7	1.1	-0.7
Worry too long after embarrassment	1.8	3.0	6.9	0.4	1.3	0.9	-1.7	-2.6	2.2	0.4	2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.1	9.0	1.4	-2.2	-2.0	1.2	1.2	-3.0	-0.2	-1.4
Wheeze or whistling in the chest in last year	0.5	1.0	3.0	-1.2	1.0	-0.3	-0.4	0.1	-1.4	1.7	0.3
Number of children fathered	2.0	2.3	6.5	-0.1	-0.8	-1.6	-0.7	2.4	-1.4	-0.0	-2.5
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	3.3	-0.5	-0.5	-0.7	-1.3	1.8	-1.1	1.1	-1.5
Age at first live birth	0.4	0.7	3.6	-0.1	0.9	0.8	0.0	-0.8	0.3	1.9	0.5
Pulse wave peak to peak time	1.0	1.2	2.5	-0.1	-1.0	0.7	-1.6	1.5	-0.1	-1.6	-1.0
Health satisfaction	0.3	0.4	1.5	-0.5	-0.4	-0.5	-0.8	0.2	-0.6	1.2	-0.4
Shortness of breath walking on level ground	0.3	0.4	1.4	0.1	-0.3	-0.3	0.4	1.2	-0.9	-0.0	-0.4
Qualifications: College or University degree	0.2	0.7	1.6	-0.5	-0.3	-0.8	-0.7	1.0	-1.1	0.2	-1.3
Eye problems/disorders: None of the above	0.9	1.0	2.8	0.8	0.6	0.1	1.0	-1.4	1.7	0.4	1.1
Mouth/teeth dental problems: Loose teeth	1.0	1.2	3.6	-0.9	1.9	0.6	0.9	-0.7	-0.4	1.9	-0.1
Emphysema/chronic bronchitis	0.6	0.7	2.3	-1.0	1.5	1.3	-0.1	-0.6	0.2	0.2	0.4
Medication for pain relief, constipation, heartburn	2.9	4.9	10.7	0.9	1.3	1.1	2.9	-2.9	3.3	0.4	2.7
Neck or shoulder pain in last month	0.6	0.8	2.9	-0.1	-0.3	-0.2	-0.6	1.1	-1.7	0.5	-1.2
Medication: Blood pressure	0.2	0.4	2.2	-0.1	0.7	0.5	-1.5	0.1	0.3	0.4	0.5
Angina (self-reported)	0.7	0.9	3.9	-0.4	0.8	2.0	0.2	-0.7	0.4	-0.8	1.0
Migraine (self-reported)	2.1	2.6	4.4	1.3	-1.8	-2.0	1.1	1.7	-1.6	1.0	-2.1
Medication: Ibuprofen	1.3	1.6	3.3	0.4	-1.7	-1.1	-0.8	1.8	-1.3	-1.0	-1.3
Medication: Allopurinol	0.1	0.1	0.3	-0.5	-0.2	0.2	-0.2	0.5	-0.3	-0.0	0.0
Medication: Omeprazole	1.3	1.5	3.9	-0.6	-0.8	0.3	-1.6	2.0	-0.7	-1.5	-1.4
Medication: Seretide 50 evohaler	4.7	5.4	12.2	-1.7	3.0	3.5	3.3	-1.2	2.1	0.0	1.5
Mean time to correctly identify matches	0.7	1.2	3.6	0.9	0.9	-0.7	1.2	-1.3	1.9	0.2	1.0
Heart disease (mother)	1.1	1.3	3.0	-1.2	1.4	1.4	0.4	-0.4	1.7	-0.1	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.4	0.2	0.5	0.4	0.3	0.2	-0.3	-0.1	-0.7
Whole body fat mass	0.3	1.2	2.8	-1.6	1.0	0.9	-1.7	0.2	0.2	1.5	0.6
Leg fat mass (right)	0.4	1.7	3.5	-1.6	1.4	1.2	-1.9	-0.2	0.3	1.6	1.0
Arm predicted mass (right)	0.2	0.8	2.6	-1.1	-0.0	1.2	-0.9	0.0	-0.6	1.6	-0.1
Pulse rate, automated reading	0.2	0.6	1.6	1.1	-0.9	-1.3	-0.2	0.8	0.1	-0.1	-0.7
Alcohol intake frequency.	0.4	0.8	4.9	0.3	0.1	0.9	-0.0	-0.5	0.7	-2.2	0.3
Comparative height size at age 10	0.4	2.2	5.2	-0.1	-1.4	-1.0	0.3	2.3	-2.1	1.0	-2.0
Number of full sisters	2.3	2.7	8.4	2.3	-2.3	-2.9	-1.4	-0.1	0.4	0.1	-0.9
Suffer from ‘nerves’	0.2	0.4	1.1	0.9	-0.6	-0.0	-0.3	0.8	-0.1	-1.0	-0.2
Overall health rating	0.4	0.8	1.8	-0.5	0.3	0.6	-0.4	1.2	-1.1	1.3	-0.9
Chest pain or discomfort	2.8	4.0	13.2	-2.9	-0.0	0.5	-1.5	1.0	-2.2	3.6	-1.3
Had major operations	2.6	3.1	8.6	-2.9	1.3	2.9	0.1	-0.6	-0.1	1.6	1.8
Age at last live birth	0.7	1.0	6.9	0.0	-0.1	-0.5	0.4	0.2	-0.5	2.6	-0.7
Family relationship satisfaction	1.6	1.9	6.3	-0.5	2.5	1.3	0.9	-1.4	1.1	0.1	1.8
Leg pain on walking	1.2	1.5	4.3	-0.2	-0.7	-0.8	-0.5	1.9	-2.1	-0.4	-1.5
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	2.1	-0.1	-0.4	1.2	-0.5	-1.5	0.5	0.5	1.1
Commuting to job workplace: Car/motor vehicle	1.8	2.0	5.5	2.3	-1.6	-1.4	0.2	-0.1	0.8	-2.3	0.2
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	4.1	1.0	0.1	-0.2	1.6	-1.7	2.0	-0.9	1.3
Medication: Aspirin	0.5	0.7	2.1	-0.1	0.4	0.4	-0.8	1.2	-0.5	-1.4	-0.6
Supplements: Vitamin C	0.7	0.8	1.9	0.9	-1.1	-1.4	-0.3	0.5	-0.1	-1.1	-0.9
Knee pain experienced in last month	0.7	1.1	3.0	-0.9	1.1	1.1	-0.9	-0.3	1.7	-1.0	0.8
Hypertension (Self-reported)	0.5	1.4	4.3	-0.5	-0.6	-0.0	-2.1	1.6	-1.5	0.5	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.6	-0.3	0.3	1.1	1.2	-1.0	0.5	-0.5	0.9
Illnesses of father: Heart disease	2.4	3.3	9.3	-1.5	0.6	-0.2	-3.1	2.2	-2.0	1.2	-2.0
Illnesses of siblings: Diabetes	0.2	0.2	0.7	-0.7	0.1	-0.3	0.4	0.3	0.8	-0.1	-0.3
Smoking status: Previous	0.4	0.6	2.0	-0.4	1.4	0.7	-1.2	0.5	0.8	-0.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	3.6	-0.4	-1.4	-0.3	0.9	1.3	-1.9	1.8	-1.5
Whole body fat-free mass	0.2	0.9	2.4	-1.0	-0.1	0.9	-1.2	0.1	-1.1	1.5	-0.4
Leg fat-free mass (right)	0.1	0.8	2.5	-1.2	0.2	1.2	-0.7	-0.2	-0.8	1.6	-0.0
Arm fat percentage (left)	0.3	1.1	2.0	-1.4	1.3	0.8	-1.3	-0.3	0.5	1.0	1.1
Average weekly red wine intake	0.5	0.7	1.7	-1.3	0.4	-0.5	-1.0	1.1	-0.1	0.2	-1.1
Handedness (chirality/laterality): Left-handed	1.2	1.4	5.4	-2.3	0.7	1.9	-0.4	0.3	-0.6	0.4	-0.7
Mood swings	0.5	0.8	3.3	-1.8	0.3	1.1	0.0	0.4	-1.0	0.7	0.5
Loneliness, isolation	2.8	3.8	9.4	0.2	-0.9	-1.4	-2.6	2.5	-3.1	0.8	-2.1
Long-standing illness, disability or infirmity	2.7	4.2	10.5	-1.3	-0.9	-0.0	-2.0	3.1	-2.4	1.1	-3.2
Ever had bowel cancer screening	1.1	1.3	3.8	0.1	-0.9	-0.7	-0.9	1.2	-1.6	0.3	-1.9
Diabetes diagnosed by doctor	0.9	1.4	5.3	-0.1	-0.3	-0.5	-1.5	2.3	-1.1	-0.7	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	3.2	-1.0	0.2	0.4	0.0	1.8	0.7	0.4	-1.1
Friendships satisfaction	1.2	1.5	4.7	-0.5	2.2	1.2	-0.2	-1.3	-0.7	1.4	1.1
Qualifications: nursing, teaching	0.6	0.9	2.5	-0.8	1.3	1.6	0.4	-0.3	0.5	1.4	-0.1
Commuting to job workplace: Walk	0.4	0.4	1.3	-1.1	0.2	0.4	-0.8	0.5	-0.6	0.1	-0.7
Eye problems/disorders: Cataract	1.1	1.3	3.6	0.1	-1.2	-1.0	-1.9	1.0	-1.4	-1.1	-0.7
Mouth/teeth dental problems: Mouth ulcers	1.5	2.3	7.3	1.6	-1.0	-0.9	-1.5	1.4	-0.8	-2.7	-1.5
Medication for cholesterol	1.9	2.9	5.7	-0.9	1.8	2.3	1.2	-1.8	2.0	0.2	2.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.1	3.7	7.0	0.7	-2.1	-2.4	-2.3	1.7	-2.6	0.6	-1.8
Back pain experienced in last month	5.2	7.7	19.4	0.4	-2.1	-1.9	-2.0	4.1	-3.5	-0.3	-4.4
Mineral and other dietary supplements	1.3	1.8	4.7	1.1	0.3	1.0	1.8	-2.2	0.1	0.2	1.9
Breast cancer (self-reported)	0.4	0.5	1.5	-0.8	1.2	0.6	-1.1	-0.2	0.1	0.5	-0.4
Asthma (self-reported)	2.0	4.0	8.2	-1.7	2.9	2.2	1.4	-1.7	1.8	1.3	2.5
Osteoporosis (self-reported)	1.7	2.1	6.3	0.9	-1.5	-1.6	-0.6	1.0	-1.1	1.6	-2.5
Osteoarthritis (self-reported)	1.3	1.6	6.5	-1.2	-0.5	-0.4	0.3	2.5	-1.2	0.5	-1.8
Medication: Aspirin	0.7	0.9	2.4	-0.1	0.2	0.2	-1.3	1.5	-0.7	-1.6	-0.9
Medication: Gliclazide	0.7	0.8	2.3	-0.1	1.5	1.5	-0.5	-0.1	0.5	-0.8	1.0
Illnesses of father: None of the above (group 1)	1.1	1.3	3.0	0.8	0.0	0.5	1.4	-1.1	1.3	-1.7	1.3
Smoking status: Current	0.4	0.7	1.9	-0.8	0.2	0.4	0.8	0.8	-1.4	1.3	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.3	9.0	22.2	-0.2	-2.5	-1.7	-4.7	3.9	-2.8	-1.3	-4.0
Whole body water mass	0.1	0.8	2.1	-0.8	-0.2	0.8	-1.2	0.1	-1.2	1.4	-0.4
Leg predicted mass (right)	0.2	0.9	3.0	-1.2	0.2	1.2	-0.8	-0.2	-0.8	1.7	-0.0
Arm fat mass (left)	0.2	1.0	2.2	-1.5	0.9	1.0	-1.4	-0.0	0.0	1.3	0.6
Number of self-reported non-cancer illnesses	0.9	1.6	5.4	-2.3	0.3	1.0	-0.4	2.2	-0.4	0.3	-1.0
Average weekly champagne plus white wine intake	1.6	2.2	4.2	1.1	-1.8	-1.3	-0.8	1.7	-1.3	-2.0	-1.4
Miserableness	0.3	0.5	1.9	-0.1	0.7	0.6	-1.1	0.1	-1.4	0.5	0.4
Guilty feelings	1.1	1.6	4.2	1.8	-0.8	-1.0	-2.1	-0.8	-0.1	-1.6	0.7
Wears glasses or contact lenses	0.5	0.6	2.4	0.1	-0.3	0.1	0.3	1.5	-0.4	-0.6	-1.1
Ever taken oral contraceptive pill	0.7	0.8	3.1	1.8	-1.4	-0.5	0.8	-0.1	-0.2	-0.7	-0.1
Hearing aid user	0.2	0.3	1.5	0.1	-0.5	0.2	-0.4	0.3	1.2	0.0	0.0
Mother’s age at death	2.1	2.6	6.3	2.5	1.0	-1.0	-0.7	-2.1	1.5	-1.7	1.7
Financial situation satisfaction	1.2	1.5	5.8	0.4	-0.3	1.3	0.2	-0.9	2.4	-1.4	1.3
Tinnitus: Yes, now most or all of the time	0.8	1.0	3.8	1.0	-0.2	0.2	2.0	0.1	-0.7	1.4	-0.5
Commuting to job workplace: Public transport	1.7	2.0	6.1	-2.1	2.5	1.4	0.2	-0.5	0.3	1.8	0.4
Eye problems/disorders: Glaucoma	0.7	0.8	3.0	-1.5	0.4	0.8	0.4	0.0	-0.8	1.7	0.0
Medication: Blood pressure	0.3	0.6	1.6	-0.3	-0.8	0.1	-1.0	1.3	-0.6	-0.1	-1.1
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.0	0.3	0.0	-0.0	0.4	0.8	-0.7	1.0	-0.5
Supplements: Fish oil (including cod liver oil)	1.4	1.8	5.6	-0.9	-0.5	-1.1	-1.1	2.4	-0.9	-0.4	-2.1
High cholesterol (Self-reported)	0.8	1.5	4.0	0.0	-0.6	-0.6	-2.0	2.0	-0.8	-1.2	-1.2
Medication: Bendroflumethiazide	0.2	0.3	1.1	-0.6	1.0	0.7	-0.2	-0.5	-0.1	0.2	0.6
Medication: Paracetamol	2.1	3.2	8.1	-2.2	0.5	0.7	-1.8	1.3	-2.8	2.5	-0.9
Medication: Lisinopril	0.2	0.3	0.6	-0.1	0.7	0.8	-0.4	0.6	0.2	0.1	-0.6
Medication: Atorvastatin	0.2	0.3	0.8	-0.0	-0.1	0.6	0.6	0.3	0.0	0.6	0.9
Illnesses of father: High blood pressure	0.4	0.5	1.9	-0.5	0.5	-0.0	-1.4	0.3	-0.7	0.9	-0.5
Alcohol drinker status: Never	1.1	1.3	3.9	-1.4	0.8	2.0	0.7	-1.2	0.8	0.7	0.9
Ever smoked	0.1	0.2	0.7	0.3	0.9	-0.0	-0.4	-0.1	-0.2	0.8	0.3
Basal metabolic rate	0.2	0.9	2.4	-1.0	0.1	1.0	-1.2	-0.1	-1.0	1.6	-0.1
Leg fat percentage (left)	0.8	2.8	5.3	-1.7	2.3	1.6	-1.5	-0.9	1.6	1.4	1.9
Arm fat-free mass (left)	0.2	0.9	2.3	-1.1	0.1	1.2	-1.3	0.1	-0.6	1.5	-0.2
Number of operations (self-reported)	2.2	3.2	10.5	-3.2	1.5	2.9	-1.2	1.3	-1.1	0.6	0.0
Average weekly beer plus cider intake	1.3	1.8	4.0	-1.1	1.4	1.1	1.2	-1.5	0.2	2.0	1.5
Irritability	0.8	1.3	4.9	-2.0	0.6	0.6	-0.7	0.1	-0.2	2.2	0.4
Risk taking	0.5	0.8	1.9	-1.0	-0.4	1.4	1.3	0.0	-0.6	-0.9	-0.2
Ever had prostate specific antigen (PSA) test	1.4	1.7	3.7	-1.5	0.0	-1.0	-1.9	1.4	-0.4	1.4	-1.5
Fractured/broken bones in last 5 years	1.8	2.4	6.6	-1.7	-0.9	0.2	-0.9	1.9	-2.6	0.8	-1.8
Age started oral contraceptive pill	0.7	0.9	2.8	-0.2	1.2	0.4	1.0	-0.2	1.7	-1.1	0.7
Diastolic blood pressure, automated reading	0.1	0.5	1.9	-0.5	0.2	-0.4	-1.4	1.0	-0.5	0.4	-0.1
Ever depressed for a whole week	1.6	2.0	6.3	0.7	-1.0	-2.5	-1.8	1.2	-1.2	0.1	-1.3
Unable to work because of sickness or disability	1.7	2.2	5.0	0.2	-1.9	-0.6	-0.2	1.4	-2.0	1.7	-2.2
Commuting to job workplace: Cycle	0.8	1.0	1.9	-1.1	0.2	1.2	0.7	-0.8	1.4	0.9	1.0
Myopia	1.2	1.7	3.7	-1.1	1.4	1.9	-1.5	-0.8	0.4	-1.5	1.1
Vascular/heart problems diagnosed by doctor	0.8	2.1	4.6	-0.0	1.4	1.0	2.1	-2.0	1.8	-0.3	1.6
Cholesterol lowering medication	0.7	1.0	1.9	0.0	-0.9	-0.6	-1.3	1.4	-0.7	-0.9	-1.3
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	4.8	-1.1	-0.4	0.2	-2.2	1.4	-0.4	-1.3	-1.1
Pain experienced in last month	2.1	3.6	8.3	-0.2	1.3	1.7	1.7	-2.4	2.6	0.6	2.9
Supplements: Calcium	0.7	0.8	2.6	-0.8	-0.1	-0.1	0.2	1.2	-1.1	0.5	-1.6
Basal cell carcinoma (self-reported)	0.6	0.7	1.5	0.4	0.4	0.2	-1.2	1.2	-1.1	0.5	-1.1
Heart attack/myocardial infarction (self-reported)	0.9	1.1	2.3	-0.7	0.8	1.5	1.2	0.3	1.1	-1.2	1.2
Deep venous thrombosis (DVT) (self-reported)	2.4	3.1	9.0	0.6	1.1	1.0	1.3	-1.9	3.0	-1.4	2.5
Heart disease (siblings)	1.3	1.6	4.6	-0.6	1.6	0.2	0.4	-2.1	0.9	0.6	1.9
Alcohol drinker status: Previous	0.6	0.6	2.3	-1.1	0.0	1.5	-0.9	0.6	0.1	-0.2	-0.7
Pack years of smoking	1.1	1.6	4.1	-0.9	1.3	1.6	-0.4	-1.6	0.8	-0.3	2.0
Impedance of whole body	0.1	0.6	1.9	1.2	-0.8	-1.4	0.4	0.3	0.3	-0.3	-0.4
Leg fat mass (left)	0.4	1.6	2.7	-1.6	1.5	1.2	-1.6	-0.2	0.5	1.5	1.1
Arm predicted mass (left)	0.2	1.0	3.2	-1.2	0.0	1.1	-1.3	0.3	-0.8	1.8	-0.4