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chr13:113,446,222-115,106,996

Best TWAS P=1.48e-12 · Best GWAS P=1.48e-23 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellar Hemisphere	TMCO3	0.17	0.07	lasso	11	0.11	8.9e-04	5.1	6.7	1.6e-11	0.32	0.14	0.05	TRUE
2	GTEx	Cells Transformed fibroblasts	TMEM255B	0.61	0.50	enet	33	0.57	5.4e-51	6.2	6.1	8.4e-10	0.57	1.00	0.00	FALSE
3	GTEx	Muscle Skeletal	TMCO3	0.25	0.18	lasso	6	0.23	2.7e-22	5.6	5.6	1.7e-08	0.15	1.00	0.00	FALSE
4	GTEx	Nerve Tibial	TMCO3	0.09	0.06	lasso	3	0.04	4.5e-04	6.2	-6.2	4.5e-10	-0.13	0.64	0.02	FALSE
5	GTEx	Thyroid	TMCO3	0.22	0.12	lasso	2	0.13	4.0e-10	6.1	-6.2	7.8e-10	-0.14	0.99	0.00	FALSE
6	METSIM	Adipose	TMEM255B	0.09	0.02	enet	29	0.07	4.1e-10	5.7	5.8	4.9e-09	0.39	0.87	0.11	FALSE
7	NTR	Blood	RASA3	0.02	0.00	bslmm	265	0.00	1.5e-02	-2.5	-7.1	1.5e-12	-0.34	0.04	0.05	TRUE
8	YFS	Blood	GAS6	0.14	0.03	lasso	8	0.07	6.8e-23	7.2	-6.7	2.1e-11	-0.54	0.91	0.09	TRUE
9	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FAM70B	0.18	0.13	enet	6	0.16	1.0e-13	-4.1	6.2	7.1e-10	0.53	1.00	0.00	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	FAM70B	0.25	0.24	enet	12	0.27	3.7e-56	-4.2	6.4	1.6e-10	0.55	1.00	0.00	FALSE
11	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FAM70B	0.31	0.18	blup	59	0.20	3.8e-10	-4.1	6.9	5.2e-12	0.62	0.92	0.07	FALSE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	FAM70B	0.07	0.06	lasso	2	0.08	1.4e-05	-4.1	6.2	5.3e-10	0.52	0.09	0.28	FALSE
13	The Cancer Genome Atlas	Esophageal Carcinoma	FAM70B	0.17	0.15	blup	59	0.15	2.4e-05	-4.2	7.0	2.8e-12	0.63	0.06	0.71	TRUE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FAM70B	0.20	0.17	enet	17	0.18	1.1e-19	-4.2	5.7	1.6e-08	0.50	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FAM70B	0.26	0.23	lasso	5	0.26	5.3e-29	-4.1	5.2	2.0e-07	0.43	1.00	0.00	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCUN1D2	0.03	0.02	blup	79	0.04	2.2e-05	5.4	-6.3	3.7e-10	-0.17	0.06	0.94	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	FAM70B	0.19	0.14	lasso	4	0.14	6.1e-16	-4.2	5.7	1.4e-08	0.49	1.00	0.00	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	TMCO3	0.05	0.04	blup	78	0.04	5.6e-05	5.5	-6.0	2.7e-09	-0.17	0.07	0.93	TRUE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	FAM70B	0.21	0.23	lasso	4	0.25	1.3e-28	-4.1	5.4	6.3e-08	0.44	1.00	0.00	FALSE
20	The Cancer Genome Atlas	Lung Adenocarcinoma	GRK1	0.04	0.02	blup	36	0.02	7.7e-04	6.6	6.7	1.5e-11	0.22	0.00	0.98	FALSE
21	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FAM70B	0.18	0.17	lasso	6	0.18	1.8e-19	-4.1	5.6	2.5e-08	0.44	1.00	0.00	FALSE
22	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FAM70B	0.23	0.24	lasso	2	0.29	3.8e-20	-4.2	6.0	2.1e-09	0.54	1.00	0.00	TRUE
23	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	FAM70B	0.46	0.21	lasso	11	0.33	1.8e-14	-4.1	6.7	2.0e-11	0.55	0.90	0.10	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	FAM70B	0.33	0.28	lasso	8	0.37	1.9e-40	-4.1	6.0	1.7e-09	0.50	1.00	0.00	FALSE
25	The Cancer Genome Atlas	Stomach Adenocarcinoma	FAM70B	0.16	0.15	lasso	5	0.13	7.5e-10	-4.1	5.5	4.6e-08	0.44	1.00	0.00	TRUE
26	The Cancer Genome Atlas	Thyroid Carcinoma	ADPRHL1	0.03	0.03	blup	70	0.03	6.9e-04	3.8	-5.5	4.9e-08	-0.17	0.09	0.25	TRUE
27	The Cancer Genome Atlas	Thyroid Carcinoma	FAM70B	0.39	0.34	lasso	7	0.38	1.6e-39	-4.2	5.9	3.3e-09	0.49	1.00	0.00	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	GRK1	0.23	0.19	enet	9	0.24	1.1e-22	4.9	5.9	4.8e-09	0.30	0.99	0.01	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	TMCO3	0.27	0.04	enet	14	0.13	9.1e-13	6.1	-6.0	1.6e-09	-0.03	0.01	0.99	TRUE
30	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	FAM70B	0.38	0.16	blup	59	0.25	1.2e-07	6.2	6.4	2.0e-10	0.57	0.19	0.64	TRUE