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chr19:20,885,811-22,643,745

Best TWAS P=1.06e-09 · Best GWAS P=1.19e-09 conditioned to 0.000105

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC641367 0.26 0.17 enet 16 0.19 4.6e-22 -5.0 -5.6 2.1e-08 0.22 0.48 0.51 FALSE
2 GTEx Artery Aorta ZNF493 0.16 0.15 lasso 4 0.18 5.1e-10 -5.9 -5.5 2.8e-08 0.91 0.01 0.99 FALSE
3 GTEx Brain Cerebellar Hemisphere ZNF493 0.26 0.04 lasso 6 0.15 1.2e-04 4.2 -5.8 8.5e-09 0.64 0.10 0.36 FALSE
4 GTEx Cells Transformed fibroblasts ZNF493 0.13 0.14 lasso 5 0.15 1.7e-11 -5.9 -5.7 1.2e-08 0.93 0.00 1.00 FALSE
5 GTEx Colon Transverse ZNF100 0.60 0.32 lasso 7 0.41 9.0e-21 -5.0 -5.2 1.8e-07 0.17 0.48 0.51 FALSE
6 GTEx Esophagus Gastroesophageal Junction ZNF100 0.69 0.28 enet 28 0.53 2.2e-22 -5.0 -5.2 1.9e-07 0.18 0.53 0.46 FALSE
7 GTEx Lung ZNF100 0.70 0.34 lasso 11 0.50 4.6e-43 -5.0 -5.2 2.5e-07 0.21 0.48 0.51 FALSE
8 GTEx Muscle Skeletal ZNF100 0.47 0.14 lasso 11 0.36 1.7e-36 -3.3 -6.1 1.1e-09 0.40 0.95 0.05 FALSE
9 GTEx Prostate ZNF493 0.37 0.21 enet 27 0.36 5.4e-10 -6.1 -5.6 2.2e-08 0.82 0.01 0.99 FALSE
10 GTEx Skin Sun Exposed Lower leg ZNF100 0.58 0.30 enet 32 0.42 8.5e-38 -5.0 -5.2 2.3e-07 0.20 0.48 0.51 FALSE
11 GTEx Testis ZNF493 0.12 0.12 lasso 5 0.10 4.2e-05 -6.1 -5.9 4.0e-09 0.99 0.00 0.99 FALSE
12 METSIM Adipose ZNF429 0.14 0.13 lasso 8 0.14 1.3e-20 4.2 -5.3 1.3e-07 0.79 0.95 0.05 FALSE
13 NTR Blood ZNF100 0.12 0.05 lasso 8 0.06 2.3e-18 -5.0 -6.1 1.1e-09 0.42 0.48 0.51 TRUE
14 YFS Blood ZNF493 0.25 0.28 lasso 9 0.33 8.8e-113 4.2 -5.2 2.3e-07 0.75 0.96 0.04 FALSE