[Hub]/) : Traits : Blood Red Count : ← →

chr19:17,728,502-20,451,172

Best TWAS P=4.8e-15 · Best GWAS P=8.89e-15 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellum	ATP13A1	0.17	0.03	enet	30	0.03	5.2e-02	-5.85	-5.2	2.2e-07	-0.21	0.10	0.05	TRUE
2	GTEx	Cells Transformed fibroblasts	ATP13A1	0.14	0.06	lasso	5	0.05	2.2e-04	6.24	6.0	1.7e-09	0.81	0.20	0.53	TRUE
3	GTEx	Colon Sigmoid	RFXANK	0.19	-0.01	enet	38	0.02	9.2e-02	7.75	-5.2	1.6e-07	-0.48	0.02	0.57	TRUE
4	GTEx	Esophagus Mucosa	LPAR2	0.08	0.03	lasso	2	0.01	1.1e-01	-5.37	5.1	2.8e-07	0.08	0.32	0.03	FALSE
5	GTEx	Esophagus Mucosa	SSBP4	0.14	0.10	lasso	2	0.14	1.3e-09	4.10	-5.2	2.5e-07	-0.03	0.64	0.35	FALSE
6	GTEx	Esophagus Muscularis	SSBP4	0.09	0.09	lasso	4	0.07	5.3e-05	7.38	-7.2	8.0e-13	-0.04	0.00	1.00	FALSE
7	GTEx	Esophagus Muscularis	UBA52	0.16	0.10	lasso	9	0.08	8.7e-06	3.86	-5.7	1.5e-08	-0.01	0.48	0.42	TRUE
8	GTEx	Liver	SSBP4	0.26	0.04	lasso	4	0.06	1.0e-02	6.74	-6.8	8.9e-12	-0.04	0.05	0.64	FALSE
9	GTEx	Lung	LPAR2	0.07	0.09	lasso	3	0.05	9.9e-05	-4.72	5.2	2.0e-07	0.16	0.89	0.01	FALSE
10	GTEx	Nerve Tibial	LPAR2	0.14	0.05	lasso	5	0.06	2.3e-05	-4.72	5.5	3.5e-08	0.19	0.73	0.01	TRUE
11	GTEx	Nerve Tibial	GMIP	0.19	0.09	lasso	6	0.03	3.9e-03	-5.04	6.0	2.1e-09	0.31	0.73	0.02	FALSE
12	GTEx	Pancreas	SSBP4	0.15	-0.01	lasso	5	0.02	3.1e-02	7.38	-7.3	2.8e-13	-0.04	0.03	0.58	FALSE
13	GTEx	Spleen	LPAR2	0.27	0.06	lasso	6	0.04	2.7e-02	-5.46	6.3	3.7e-10	0.22	0.12	0.08	TRUE
14	GTEx	Testis	UBA52	0.17	0.03	enet	10	0.04	5.6e-03	-4.59	-6.1	1.2e-09	-0.02	0.11	0.64	TRUE
15	GTEx	Whole Blood	LPAR2	0.10	0.07	lasso	5	0.07	8.0e-07	-4.72	6.3	3.1e-10	0.33	0.97	0.00	TRUE
16	GTEx	Whole Blood	ELL	0.10	0.03	enet	17	0.04	1.2e-04	4.53	5.6	2.7e-08	0.04	0.17	0.79	FALSE
17	GTEx	Whole Blood	LRRC25	0.12	0.01	enet	7	0.02	1.0e-02	4.48	-5.4	6.4e-08	-0.03	0.10	0.83	FALSE
18	METSIM	Adipose	GMIP	0.07	0.03	lasso	4	0.03	7.8e-05	-5.10	5.9	3.1e-09	0.47	0.42	0.20	FALSE
19	METSIM	Adipose	LRRC25	0.04	0.01	bslmm	385	0.01	2.8e-02	4.75	-6.8	1.3e-11	-0.02	0.13	0.06	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	ATP13A1	0.10	0.07	lasso	5	0.06	1.3e-08	7.15	-7.1	9.1e-13	-0.77	0.07	0.93	TRUE
21	YFS	Blood	LSM4	0.19	0.01	enet	33	0.09	3.4e-27	6.03	-6.3	3.1e-10	0.05	0.96	0.04	TRUE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	MEF2B	0.05	0.01	blup	61	0.03	3.2e-06	3.99	-6.3	3.2e-10	-0.61	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	LRRC25	0.14	0.07	enet	5	0.10	8.3e-06	4.75	-5.8	8.6e-09	-0.02	0.16	0.10	FALSE
24	The Cancer Genome Atlas	Colon Adenocarcinoma	ISYNA1	0.08	0.09	lasso	4	0.09	7.0e-06	6.90	6.8	9.2e-12	0.04	0.00	0.99	FALSE
25	The Cancer Genome Atlas	Colon Adenocarcinoma	SSBP4	0.08	0.05	enet	9	0.07	6.7e-05	4.60	-5.4	8.4e-08	0.01	0.10	0.68	FALSE
26	The Cancer Genome Atlas	Colon Adenocarcinoma	TSSK6	0.07	0.02	blup	32	0.04	2.9e-03	-4.54	-5.2	1.8e-07	-0.38	0.05	0.10	FALSE
27	The Cancer Genome Atlas	Glioblastoma Multiforme	ELL	0.13	0.10	blup	46	0.08	1.9e-03	4.73	-6.7	2.4e-11	-0.04	0.08	0.42	FALSE
28	The Cancer Genome Atlas	Glioblastoma Multiforme	LRRC25	0.20	0.12	lasso	3	0.12	1.2e-04	5.06	-5.9	4.7e-09	-0.02	0.01	0.44	FALSE
29	The Cancer Genome Atlas	Glioblastoma Multiforme	UBA52	0.16	0.10	lasso	4	0.07	3.9e-03	6.42	-6.9	5.6e-12	-0.03	0.02	0.16	FALSE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SSBP4	0.04	0.03	blup	37	0.04	1.6e-05	4.73	-6.0	2.7e-09	-0.03	0.36	0.56	FALSE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ELL	0.06	0.01	blup	48	0.03	4.8e-04	6.95	5.5	4.2e-08	0.04	0.03	0.88	FALSE
32	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C19orf50	0.12	0.00	enet	11	0.01	6.5e-02	0.89	-5.1	2.9e-07	-0.01	0.01	0.54	FALSE
33	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LRRC25	0.10	0.08	lasso	3	0.08	2.0e-05	5.06	-5.6	2.1e-08	-0.02	0.06	0.93	FALSE
34	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SSBP4	0.06	0.07	enet	6	0.07	5.6e-05	4.48	-5.7	1.5e-08	-0.04	0.04	0.95	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	C19orf50	0.07	0.00	blup	42	0.04	5.6e-05	-4.59	-7.1	1.3e-12	-0.01	0.01	0.92	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	LRRC25	0.07	0.08	blup	46	0.09	2.2e-10	4.65	-5.1	3.0e-07	-0.02	0.94	0.06	FALSE
37	The Cancer Genome Atlas	Lung Adenocarcinoma	LRRC25	0.04	0.01	blup	45	0.02	6.2e-04	4.65	-5.5	2.9e-08	-0.02	0.18	0.52	FALSE
38	The Cancer Genome Atlas	Lung Adenocarcinoma	YJEFN3	0.03	0.03	blup	32	0.02	3.0e-03	-4.54	5.3	9.1e-08	0.34	0.10	0.11	FALSE
39	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SSBP4	0.02	0.03	lasso	2	0.03	5.3e-04	6.92	-6.7	1.5e-11	-0.05	0.00	0.97	FALSE
40	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LRRC25	0.07	0.03	blup	46	0.02	8.5e-03	4.75	-6.5	9.9e-11	-0.01	0.04	0.35	TRUE
41	The Cancer Genome Atlas	Prostate Adenocarcinoma	C19orf50	0.04	0.02	enet	5	0.03	1.1e-03	-4.61	-5.4	6.7e-08	0.00	0.03	0.13	TRUE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	ELL	0.03	0.03	blup	47	0.01	1.2e-02	4.88	-5.7	9.8e-09	-0.03	0.11	0.44	FALSE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	SSBP4	0.04	0.08	enet	13	0.08	8.4e-09	4.60	-5.2	2.1e-07	-0.03	0.54	0.46	FALSE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	UBA52	0.05	0.05	enet	14	0.05	1.1e-05	3.58	-7.2	4.1e-13	0.03	0.41	0.18	FALSE
45	The Cancer Genome Atlas	Stomach Adenocarcinoma	SSBP4	0.05	0.00	blup	37	0.02	8.7e-03	6.90	-7.8	4.8e-15	-0.04	0.00	0.73	TRUE
46	The Cancer Genome Atlas	Thyroid Carcinoma	ELL	0.06	0.06	blup	46	0.09	1.2e-08	4.88	-7.0	3.7e-12	-0.04	0.07	0.93	FALSE
47	The Cancer Genome Atlas	Thyroid Carcinoma	ISYNA1	0.04	0.00	blup	34	0.02	4.8e-03	6.60	6.6	5.4e-11	0.05	0.01	0.92	FALSE
48	The Cancer Genome Atlas	Thyroid Carcinoma	LRRC25	0.05	0.08	lasso	3	0.07	5.4e-07	4.75	-5.2	1.7e-07	-0.01	0.85	0.14	FALSE
49	The Cancer Genome Atlas	Thyroid Carcinoma	UBA52	0.04	0.02	blup	40	0.04	1.1e-04	-4.61	-5.4	7.3e-08	-0.03	0.08	0.87	FALSE
50	The Cancer Genome Atlas	Thyroid Carcinoma	YJEFN3	0.08	0.06	blup	33	0.08	7.1e-08	-4.52	5.5	3.1e-08	0.33	0.96	0.02	FALSE