Best TWAS P=2.54e-09 · Best GWAS P=3.99e-10 conditioned to 0.0559
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | LAMC1 | 0.08 | 0.05 | enet | 21 | 0.04 | 1.0e-04 | -4 | -5.6 | 2.3e-08 | -0.82 | 0.19 | 0.81 | FALSE |
| 2 | NTR | Blood | LAMC1 | 0.05 | 0.07 | lasso | 11 | 0.07 | 3.7e-21 | 6 | -5.9 | 3.9e-09 | -0.95 | 0.01 | 0.99 | FALSE |
| 3 | YFS | Blood | LAMC1 | 0.10 | 0.17 | lasso | 21 | 0.17 | 2.7e-52 | 6 | -6.0 | 2.5e-09 | -0.94 | 0.01 | 0.99 | TRUE |