Best TWAS P=4.25e-10 · Best GWAS P=6.56e-08 conditioned to 0.122
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells EBV-transformed lymphocytes | SMARCB1 | 0.31 | 0.15 | lasso | 16 | 0.12 | 7.6e-05 | -5.4 | -5.1 | 2.7e-07 | 0.95 | 0.01 | 0.97 | FALSE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C22orf15 | 0.04 | 0.00 | blup | 38 | 0.02 | 1.3e-03 | 4.1 | 6.2 | 4.2e-10 | -0.69 | 0.01 | 0.46 | TRUE |