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chr22:32,174,198-33,589,432

Best TWAS P=5.86e-52 · Best GWAS P=4.46e-42 conditioned to 0.667

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Thyroid Carcinoma	FBXO7	0.05	0.03	lasso	5	0.03	2.5e-04	-13.6	-15.2	5.9e-52	0.95	0.01	0.98	TRUE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FBXO7	0.12	0.06	lasso	1	0.06	6.4e-07	12.5	-12.5	6.5e-36	0.38	0.91	0.01	TRUE
6	GTEx	Nerve Tibial	FBXO7	0.37	0.35	lasso	2	0.33	6.0e-24	-13.6	13.6	2.2e-42	-1.00	0.00	1.00	FALSE
8	GTEx	Skin Sun Exposed Lower leg	FBXO7	0.27	0.19	enet	15	0.20	2.6e-16	12.9	13.6	3.5e-42	-0.73	0.92	0.08	FALSE
2	GTEx	Adipose Subcutaneous	FBXO7	0.13	0.04	enet	16	0.07	2.3e-06	-13.6	13.4	6.6e-41	-0.81	0.01	0.99	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	FBXO7	0.35	0.22	lasso	8	0.24	4.4e-13	13.0	12.6	2.4e-36	-0.62	0.92	0.08	FALSE
10	The Cancer Genome Atlas	Brain Lower Grade Glioma	FBXO7	0.25	0.09	enet	15	0.20	2.2e-22	-13.6	11.2	3.0e-29	-0.79	0.00	1.00	FALSE
3	GTEx	Brain Hippocampus	FBXO7	0.36	0.09	lasso	7	0.12	9.4e-04	-13.6	11.1	8.0e-29	-0.86	0.01	0.93	FALSE
4	GTEx	Esophagus Mucosa	FBXO7	0.29	0.07	lasso	6	0.11	7.4e-08	12.9	10.4	3.4e-25	-0.57	0.93	0.07	FALSE
5	GTEx	Lung	FBXO7	0.14	0.01	lasso	6	0.00	3.6e-01	2.3	10.0	1.8e-23	-0.66	0.03	0.84	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FBXO7	0.11	0.06	lasso	3	0.06	4.6e-08	2.3	8.2	2.2e-16	-0.62	0.09	0.91	FALSE