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chr22:36,707,661-41,466,229

Best TWAS P=2.37e-21 · Best GWAS P=8.99e-24 conditioned to 0.000127

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CBX7	0.09	0.07	bslmm	416	0.06	2.7e-07	-5.3	-6.0	1.8e-09	-0.07	0.86	0.14	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MICALL1	0.10	0.04	blup	388	0.05	6.2e-07	5.4	-5.5	3.6e-08	-0.03	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	POLR2F	0.06	0.05	blup	389	0.05	5.5e-07	5.0	-6.4	1.6e-10	0.04	0.99	0.00	FALSE
4	CommonMind	Brain Pre-frontal Cortex	TRIOBP	0.20	0.20	bslmm	501	0.21	4.3e-25	4.6	-5.2	1.7e-07	0.02	1.00	0.00	FALSE
5	CommonMind	Brain Pre-frontal Cortex	TST	0.13	0.11	lasso	6	0.11	2.0e-13	-7.1	-7.4	1.4e-13	-0.39	1.00	0.00	FALSE
6	GTEx	Adipose Subcutaneous	TRIOBP	0.13	0.14	lasso	7	0.14	3.9e-11	4.9	-5.3	1.2e-07	0.03	1.00	0.00	FALSE
7	GTEx	Adipose Subcutaneous	GCAT	0.16	0.12	lasso	5	0.12	9.2e-10	5.2	5.4	8.2e-08	-0.04	1.00	0.00	FALSE
8	GTEx	Adipose Subcutaneous	BAIAP2L2	0.11	0.03	lasso	5	0.04	1.8e-04	-5.7	6.8	7.5e-12	0.02	0.15	0.37	FALSE
9	GTEx	Artery Aorta	TRIOBP	0.13	0.10	lasso	8	0.11	1.1e-06	4.9	-5.2	1.6e-07	0.01	0.98	0.01	FALSE
10	GTEx	Artery Aorta	MICALL1	0.11	0.06	lasso	2	0.02	1.5e-02	5.6	5.7	1.4e-08	-0.01	0.63	0.05	FALSE
11	GTEx	Artery Aorta	RP5-1039K5.17	0.07	0.04	lasso	2	0.04	3.0e-03	5.4	5.3	9.2e-08	-0.03	0.27	0.03	FALSE
12	GTEx	Artery Coronary	TRIOBP	0.27	0.14	lasso	4	0.14	2.2e-05	5.1	-5.8	8.8e-09	0.01	0.29	0.12	FALSE
13	GTEx	Artery Tibial	GCAT	0.09	0.09	lasso	2	0.08	3.5e-07	6.9	6.8	1.3e-11	0.00	0.16	0.84	TRUE
14	GTEx	Artery Tibial	MICALL1	0.11	0.04	lasso	4	0.05	8.4e-05	5.6	5.7	1.4e-08	0.00	0.58	0.11	FALSE
15	GTEx	Artery Tibial	C22orf23	0.08	0.05	lasso	2	0.05	4.2e-05	5.6	5.7	1.2e-08	-0.02	0.96	0.02	FALSE
16	GTEx	Brain Cortex	TMEM184B	0.29	0.12	lasso	7	0.09	1.6e-03	-6.8	7.1	1.1e-12	0.01	0.02	0.82	TRUE
17	GTEx	Breast Mammary Tissue	TRIOBP	0.11	0.10	enet	13	0.09	3.3e-05	5.2	-6.0	2.7e-09	0.04	0.83	0.02	FALSE
18	GTEx	Cells Transformed fibroblasts	TRIOBP	0.08	0.03	enet	11	0.09	3.0e-07	4.6	-5.3	1.2e-07	0.01	0.96	0.00	FALSE
19	GTEx	Cells Transformed fibroblasts	PLA2G6	0.23	0.09	lasso	9	0.10	9.9e-08	-5.8	-6.2	4.3e-10	-0.08	0.24	0.76	FALSE
20	GTEx	Esophagus Mucosa	PLA2G6	0.22	0.02	lasso	6	0.04	1.9e-03	-5.8	-5.5	3.4e-08	-0.09	0.21	0.75	FALSE
21	GTEx	Esophagus Muscularis	TRIOBP	0.07	0.06	lasso	3	0.06	1.7e-04	5.6	-5.7	1.4e-08	0.03	0.70	0.02	FALSE
22	GTEx	Esophagus Muscularis	GCAT	0.11	0.12	lasso	3	0.12	1.1e-07	4.9	5.4	6.7e-08	-0.04	0.99	0.00	FALSE
23	GTEx	Heart Left Ventricle	TRIOBP	0.16	0.04	lasso	4	0.08	6.2e-05	4.6	-5.4	6.9e-08	0.03	0.84	0.05	FALSE
24	GTEx	Lung	GCAT	0.10	0.09	lasso	2	0.07	9.7e-06	5.2	5.3	1.4e-07	-0.04	0.97	0.01	FALSE
25	GTEx	Nerve Tibial	TRIOBP	0.20	0.18	lasso	7	0.22	9.1e-16	4.9	-5.6	2.3e-08	0.02	1.00	0.00	FALSE
26	GTEx	Nerve Tibial	PLA2G6	0.34	0.08	lasso	8	0.11	2.9e-08	3.5	-5.2	1.5e-07	-0.07	0.27	0.73	FALSE
27	GTEx	Nerve Tibial	MAFF	0.14	0.06	lasso	3	0.05	1.2e-04	-7.0	7.1	1.7e-12	0.05	0.01	0.99	FALSE
28	GTEx	Pancreas	GCAT	0.32	0.23	lasso	6	0.26	2.4e-11	5.3	-5.3	1.4e-07	0.06	1.00	0.00	FALSE
29	GTEx	Pancreas	PLA2G6	0.28	0.00	lasso	6	0.01	1.4e-01	3.5	-6.8	9.4e-12	-0.06	0.10	0.12	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	TRIOBP	0.12	0.04	lasso	3	0.05	7.0e-04	5.1	-5.3	1.1e-07	0.01	0.57	0.06	FALSE
31	GTEx	Skin Sun Exposed Lower leg	TRIOBP	0.06	0.06	lasso	4	0.06	1.7e-05	5.1	-5.2	2.0e-07	-0.01	0.88	0.03	FALSE
32	GTEx	Skin Sun Exposed Lower leg	BAIAP2L2	0.09	0.09	lasso	4	0.09	5.5e-08	-5.5	5.5	3.4e-08	0.11	0.43	0.56	FALSE
33	GTEx	Testis	ADSL	0.18	0.13	lasso	4	0.10	5.2e-05	5.0	5.5	3.4e-08	-0.07	0.20	0.35	FALSE
34	GTEx	Whole Blood	TRIOBP	0.18	0.05	enet	29	0.14	1.7e-12	4.9	-7.0	2.2e-12	0.03	1.00	0.00	FALSE
35	GTEx	Whole Blood	CBX6	0.08	0.03	enet	15	0.03	1.4e-03	1.8	5.2	1.9e-07	0.02	0.04	0.67	FALSE
36	GTEx	Whole Blood	H1F0	0.10	0.04	enet	17	0.08	1.1e-07	6.9	6.2	7.1e-10	0.02	0.15	0.85	FALSE
37	NTR	Blood	SH3BP1	0.02	0.00	blup	497	0.01	5.0e-03	2.8	5.9	3.4e-09	-0.06	0.06	0.37	FALSE
38	YFS	Blood	CBX7	0.04	0.02	blup	395	0.02	1.2e-08	6.7	-6.2	6.6e-10	-0.03	0.01	0.99	TRUE
39	YFS	Blood	H1F0	0.42	0.34	lasso	7	0.42	6.3e-150	6.9	5.8	4.9e-09	0.01	0.12	0.88	FALSE
40	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIOBP	0.04	0.05	enet	16	0.06	3.0e-13	4.9	-5.6	1.7e-08	0.02	0.29	0.71	FALSE
41	The Cancer Genome Atlas	Glioblastoma Multiforme	GALR3	0.09	0.04	blup	27	0.06	8.8e-03	6.9	6.2	4.8e-10	-0.02	0.01	0.80	FALSE
42	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADSL	0.04	0.03	enet	6	0.03	1.6e-04	5.6	6.4	1.2e-10	-0.02	0.03	0.49	TRUE
43	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLA2G6	0.05	0.01	blup	76	0.01	7.7e-02	-6.4	-6.9	5.2e-12	-0.06	0.01	0.81	FALSE
44	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TRIOBP	0.11	0.09	enet	10	0.11	5.5e-12	5.1	-5.3	1.1e-07	0.01	0.83	0.17	FALSE
45	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TRIOBP	0.12	0.14	enet	8	0.12	3.1e-07	5.3	-5.8	5.5e-09	-0.01	0.09	0.91	FALSE
46	The Cancer Genome Atlas	Brain Lower Grade Glioma	GALR3	0.04	0.04	lasso	2	0.05	3.4e-06	5.6	5.8	7.5e-09	-0.01	0.04	0.95	FALSE
47	The Cancer Genome Atlas	Brain Lower Grade Glioma	GCAT	0.07	0.06	lasso	4	0.06	2.0e-07	5.3	-5.4	5.9e-08	0.04	0.71	0.29	FALSE
48	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRIOBP	0.08	0.07	enet	11	0.08	6.1e-09	5.3	-5.7	1.6e-08	0.03	0.05	0.95	FALSE
49	The Cancer Genome Atlas	Lung Adenocarcinoma	ADSL	0.03	0.00	blup	33	0.01	8.9e-03	5.7	5.2	2.5e-07	0.02	0.01	0.53	FALSE
50	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ADSL	0.06	0.02	lasso	2	0.03	6.6e-03	5.8	5.4	8.5e-08	-0.06	0.02	0.13	FALSE
51	The Cancer Genome Atlas	Prostate Adenocarcinoma	ADSL	0.08	0.02	enet	5	0.02	2.3e-03	4.6	5.6	2.3e-08	0.03	0.05	0.36	FALSE
52	The Cancer Genome Atlas	Prostate Adenocarcinoma	GALR3	0.11	0.16	lasso	4	0.15	4.9e-15	5.2	5.3	1.2e-07	-0.04	0.94	0.06	FALSE
53	The Cancer Genome Atlas	Prostate Adenocarcinoma	SGSM3	0.06	0.01	lasso	4	0.01	7.4e-02	-6.5	5.5	4.5e-08	0.05	0.00	0.94	FALSE
54	The Cancer Genome Atlas	Soft Tissue Sarcoma	KCTD17	0.08	0.00	enet	7	0.00	4.7e-01	-3.8	-5.3	1.4e-07	-0.62	0.07	0.06	FALSE
55	The Cancer Genome Atlas	Thyroid Carcinoma	GCAT	0.02	0.03	blup	29	0.03	1.4e-03	4.9	5.4	8.0e-08	-0.03	0.04	0.41	FALSE
56	The Cancer Genome Atlas	Thyroid Carcinoma	MPST	0.08	0.09	lasso	5	0.06	1.4e-06	8.2	8.4	6.5e-17	0.75	0.47	0.52	FALSE
57	The Cancer Genome Atlas	Thyroid Carcinoma	PLA2G6	0.03	0.02	lasso	2	0.03	6.5e-04	-5.9	-5.9	4.1e-09	-0.05	0.06	0.41	FALSE
58	The Cancer Genome Atlas	Thyroid Carcinoma	POLR2F	0.02	0.02	blup	34	0.02	9.4e-03	5.4	5.2	1.8e-07	-0.04	0.03	0.48	FALSE
59	The Cancer Genome Atlas	Thyroid Carcinoma	TST	0.05	0.04	lasso	2	0.04	9.9e-05	8.2	9.5	2.4e-21	0.82	0.00	0.95	TRUE
60	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	GCAT	0.17	0.05	blup	29	0.07	4.8e-03	6.9	-6.2	5.6e-10	-0.01	0.00	0.92	FALSE