[Hub]/) : Traits : Blood Red Count : ← →

chr1:223,607,389-225,310,170

Best TWAS P=7.75e-13 · Best GWAS P=2.44e-09 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
18	GTEx	Muscle Skeletal	DEGS1	0.08	0.05	lasso	6	0.05	1.5e-05	4.9	7.2	7.8e-13	-0.29	0.28	0.33	TRUE
21	GTEx	Pancreas	CNIH4	0.21	0.07	enet	23	0.08	4.0e-04	5.6	-7.1	1.7e-12	0.20	0.04	0.95	TRUE
3	GTEx	Adipose Subcutaneous	CNIH4	0.24	0.16	enet	38	0.20	3.5e-16	5.9	-6.3	2.7e-10	0.28	0.03	0.97	TRUE
27	METSIM	Adipose	CNIH4	0.16	0.20	lasso	2	0.20	2.4e-29	5.9	-6.0	2.7e-09	0.21	0.02	0.98	TRUE
39	The Cancer Genome Atlas	Thyroid Carcinoma	CNIH4	0.09	0.09	enet	10	0.09	3.7e-09	5.9	-5.3	1.3e-07	0.23	0.01	0.99	TRUE
1	CommonMind	Brain Pre-frontal Cortex	CNIH4	0.07	0.04	enet	12	0.03	6.2e-05	4.9	-6.8	1.4e-11	0.40	0.48	0.36	FALSE
28	NTR	Blood	CNIH4	0.02	0.02	lasso	5	0.02	1.7e-06	5.9	-6.7	2.3e-11	0.23	0.03	0.97	FALSE
4	GTEx	Adipose Visceral Omentum	CNIH4	0.23	0.19	enet	34	0.22	1.7e-11	5.9	-6.3	2.6e-10	0.21	0.03	0.97	FALSE
29	YFS	Blood	CNIH4	0.12	0.13	bslmm	358	0.13	5.1e-40	5.7	-6.2	4.1e-10	0.23	0.04	0.96	FALSE
5	GTEx	Adrenal Gland	CNIH4	0.21	0.05	lasso	6	0.13	2.5e-05	5.9	-6.1	1.4e-09	0.24	0.03	0.96	FALSE
23	GTEx	Skin Sun Exposed Lower leg	CNIH4	0.28	0.26	lasso	8	0.26	8.6e-22	5.8	-5.9	3.0e-09	0.22	0.03	0.97	FALSE
9	GTEx	Breast Mammary Tissue (Female)	CNIH4	0.12	0.16	lasso	4	0.14	7.8e-05	5.9	-5.9	3.5e-09	0.21	0.03	0.90	FALSE
35	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CNIH4	0.19	0.22	lasso	15	0.20	7.3e-09	5.9	-5.9	4.1e-09	0.21	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FBXO28	0.03	0.01	bslmm	356	0.01	2.1e-02	-5.0	5.9	4.6e-09	-0.72	0.04	0.67	FALSE
22	GTEx	Skin Not Sun Exposed Suprapubic	CNIH4	0.22	0.22	lasso	4	0.21	7.4e-12	5.9	-5.9	4.7e-09	0.21	0.03	0.97	FALSE
19	GTEx	Muscle Skeletal	CNIH4	0.13	0.16	lasso	7	0.16	4.5e-15	5.7	-5.8	5.0e-09	0.21	0.03	0.97	FALSE
38	The Cancer Genome Atlas	Stomach Adenocarcinoma	CNIH4	0.07	0.05	lasso	10	0.04	7.1e-04	5.7	-5.8	5.8e-09	0.22	0.01	0.98	FALSE
16	GTEx	Heart Left Ventricle	CNIH4	0.11	0.09	enet	12	0.09	2.0e-05	5.8	-5.8	7.8e-09	0.21	0.03	0.95	FALSE
6	GTEx	Artery Tibial	CNIH4	0.15	0.14	lasso	4	0.16	1.1e-12	5.8	-5.8	8.1e-09	0.21	0.03	0.97	FALSE
25	GTEx	Thyroid	CNIH4	0.20	0.23	lasso	3	0.25	8.4e-19	5.8	-5.8	8.1e-09	0.21	0.03	0.97	FALSE
15	GTEx	Heart Atrial Appendage	CNIH4	0.20	0.11	lasso	6	0.07	3.3e-04	5.7	-5.8	8.3e-09	0.21	0.04	0.95	FALSE
34	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CNIH4	0.02	0.02	lasso	5	0.01	1.0e-02	5.7	-5.8	8.4e-09	0.21	0.01	0.87	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	CNIH4	0.08	0.14	enet	13	0.15	2.4e-15	5.7	-5.7	9.3e-09	0.22	0.02	0.98	FALSE
10	GTEx	Cells Transformed fibroblasts	CNIH4	0.14	0.07	enet	9	0.10	3.3e-08	5.9	-5.7	1.0e-08	0.18	0.03	0.97	FALSE
31	The Cancer Genome Atlas	Esophageal Carcinoma	CNIH4	0.10	0.07	lasso	7	0.06	7.3e-03	5.7	-5.7	1.1e-08	0.21	0.01	0.71	FALSE
26	GTEx	Whole Blood	CNIH4	0.07	0.04	lasso	2	0.05	2.0e-05	5.6	-5.7	1.2e-08	0.22	0.03	0.96	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	DEGS1	0.09	0.06	lasso	4	0.05	7.6e-06	-5.4	5.7	1.2e-08	-0.51	0.08	0.91	FALSE
8	GTEx	Breast Mammary Tissue (Male)	CNIH4	0.26	0.16	lasso	4	0.11	2.0e-03	5.7	-5.7	1.4e-08	0.21	0.03	0.85	FALSE
30	YFS	Blood	FBXO28	0.26	0.37	lasso	6	0.37	1.4e-129	-5.8	-5.6	1.8e-08	0.99	0.02	0.98	FALSE
7	GTEx	Breast Mammary Tissue	CNIH4	0.25	0.19	lasso	5	0.22	1.6e-11	5.7	-5.6	2.0e-08	0.23	0.03	0.97	FALSE
20	GTEx	Nerve Tibial	CNIH4	0.26	0.20	lasso	10	0.22	6.2e-16	5.7	-5.6	2.8e-08	0.21	0.03	0.97	FALSE
17	GTEx	Lung	CNIH4	0.25	0.20	lasso	15	0.25	1.9e-19	5.7	-5.5	3.0e-08	0.23	0.03	0.97	FALSE
12	GTEx	Esophagus Gastroesophageal Junction	CNIH4	0.21	0.13	lasso	5	0.11	9.8e-05	5.7	-5.5	3.3e-08	0.23	0.04	0.95	FALSE
14	GTEx	Esophagus Muscularis	CNIH4	0.23	0.22	lasso	4	0.24	8.0e-15	5.6	-5.5	4.1e-08	0.22	0.04	0.96	FALSE
33	The Cancer Genome Atlas	Lung Adenocarcinoma	CNIH4	0.03	0.01	blup	33	0.01	6.1e-02	5.8	-5.5	4.8e-08	0.22	0.01	0.96	FALSE
11	GTEx	Colon Transverse	CNIH4	0.28	0.20	enet	37	0.23	1.9e-11	5.8	-5.5	5.0e-08	0.31	0.04	0.96	FALSE
24	GTEx	Skin Sun Exposed Lower leg	WDR26	0.08	0.00	lasso	2	0.01	5.1e-02	-2.6	-5.3	1.2e-07	0.22	0.06	0.62	FALSE
32	The Cancer Genome Atlas	Brain Lower Grade Glioma	DEGS1	0.03	0.03	enet	5	0.03	2.9e-04	-5.5	5.2	1.9e-07	-0.40	0.04	0.58	FALSE
13	GTEx	Esophagus Mucosa	CNIH4	0.20	0.19	lasso	5	0.18	2.0e-12	5.7	-5.1	2.8e-07	0.21	0.04	0.96	FALSE