[Hub]/) : Traits : Blood Red Count :

chr1:228,715,705-232,181,815

Best TWAS P=1.01e-36 · Best GWAS P=4.25e-32 conditioned to 3.35e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RAB4A 0.04 0.00 blup 489 0.02 2.0e-03 6.3 -5.2 2.0e-07 0.06 0.02 0.83 FALSE
2 GTEx Adipose Subcutaneous C1orf131 0.11 0.00 enet 24 0.04 6.5e-04 10.2 5.5 4.7e-08 -0.26 0.06 0.36 TRUE
3 GTEx Cells Transformed fibroblasts SPRTN 0.05 0.02 enet 8 0.01 3.2e-02 -10.8 -8.7 2.7e-18 0.71 0.04 0.77 FALSE
4 GTEx Esophagus Mucosa SPRTN 0.06 0.05 lasso 3 0.02 1.8e-02 -11.3 -11.3 2.1e-29 0.97 0.06 0.88 FALSE
5 GTEx Heart Atrial Appendage GNPAT 0.13 0.00 lasso 5 0.01 1.7e-01 -2.9 6.7 2.4e-11 -0.58 0.06 0.38 FALSE
6 GTEx Nerve Tibial ARV1 0.10 0.02 enet 17 0.02 1.3e-02 -4.2 5.7 1.4e-08 -0.08 0.45 0.02 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic ARV1 0.14 -0.01 lasso 4 0.00 5.0e-01 -2.2 7.9 3.3e-15 -0.18 0.11 0.21 TRUE
8 GTEx Testis SPRTN 0.10 0.08 lasso 6 0.05 3.0e-03 -11.4 -10.8 2.3e-27 0.91 0.07 0.89 FALSE
9 GTEx Testis TTC13 0.32 0.19 lasso 3 0.23 1.5e-10 -6.1 -5.4 5.5e-08 0.03 1.00 0.00 FALSE
10 NTR Blood C1orf124 0.05 0.06 lasso 3 0.07 3.1e-21 -11.4 -11.3 1.8e-29 0.97 0.04 0.96 FALSE
11 YFS Blood ARV1 0.05 0.05 lasso 4 0.05 4.8e-16 -6.0 5.8 4.9e-09 -0.05 1.00 0.00 FALSE
12 YFS Blood EXOC8 0.06 0.08 lasso 3 0.08 8.2e-26 -10.2 -10.0 1.5e-23 0.83 1.00 0.00 FALSE
13 YFS Blood NUP133 0.02 0.00 bslmm 431 0.01 2.8e-03 3.7 -5.3 9.6e-08 0.04 0.63 0.05 FALSE
14 YFS Blood TAF5L 0.01 0.02 lasso 1 0.01 1.8e-05 6.0 -6.0 2.2e-09 -0.02 0.01 0.99 TRUE
15 The Cancer Genome Atlas Breast Invasive Carcinoma C1orf124 0.03 0.02 blup 44 0.02 3.3e-04 -11.8 -11.2 5.8e-29 0.97 0.01 0.98 FALSE
16 The Cancer Genome Atlas Colon Adenocarcinoma C1orf124 0.04 0.03 blup 44 0.04 1.9e-03 -11.1 -11.2 6.9e-29 0.98 0.03 0.71 FALSE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EGLN1 0.04 0.04 blup 64 0.03 8.9e-05 -1.9 7.3 3.4e-13 -0.83 0.17 0.75 FALSE
18 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EGLN1 0.07 0.02 blup 64 0.04 3.5e-03 -11.4 -12.7 1.0e-36 0.87 0.05 0.67 TRUE
19 The Cancer Genome Atlas Brain Lower Grade Glioma C1orf124 0.05 0.01 blup 44 0.03 5.3e-04 -11.4 -11.6 6.9e-31 0.82 0.01 0.96 FALSE
20 The Cancer Genome Atlas Lung Adenocarcinoma C1orf124 0.02 0.02 lasso 2 0.01 8.8e-03 -11.1 -11.5 1.7e-30 0.97 0.01 0.86 FALSE
21 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TTC13 0.04 0.04 blup 90 0.03 3.0e-03 -4.1 5.2 2.3e-07 -0.08 0.02 0.82 FALSE
22 The Cancer Genome Atlas Prostate Adenocarcinoma C1orf124 0.08 0.05 blup 44 0.04 2.8e-05 -11.8 -11.1 1.8e-28 0.97 0.01 0.99 FALSE
23 The Cancer Genome Atlas Prostate Adenocarcinoma EGLN1 0.02 0.02 lasso 1 0.01 1.4e-02 -11.4 -11.4 3.1e-30 0.97 0.03 0.83 FALSE
24 The Cancer Genome Atlas Rectum Adenocarcinoma EXOC8 0.16 0.03 enet 8 0.04 3.5e-02 -10.8 7.2 5.0e-13 -0.79 0.01 0.29 FALSE
25 The Cancer Genome Atlas Soft Tissue Sarcoma C1orf124 0.04 0.04 enet 7 0.05 5.2e-04 -11.7 -11.4 5.4e-30 0.97 0.02 0.92 FALSE
26 The Cancer Genome Atlas Thyroid Carcinoma C1orf124 0.04 0.05 enet 7 0.06 3.8e-06 -11.4 -10.8 4.9e-27 0.98 0.02 0.98 FALSE