Best TWAS P=1.15e-08 · Best GWAS P=1.09e-08 conditioned to 9.01e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | SP140L | 0.12 | 0.09 | enet | 17 | 0.08 | 5.0e-07 | 3.9 | -5.1 | 3.0e-07 | 0.03 | 0.95 | 0.03 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | SP140L | 0.06 | 0.02 | blup | 96 | 0.03 | 1.4e-03 | 1.6 | -5.4 | 6.5e-08 | 0.20 | 0.30 | 0.09 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SP140 | 0.04 | 0.00 | blup | 134 | 0.00 | 1.1e-01 | -5.7 | 5.3 | 9.6e-08 | -0.81 | 0.01 | 0.81 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | SP140L | 0.05 | 0.00 | blup | 96 | 0.02 | 1.0e-02 | 1.5 | -5.7 | 1.2e-08 | 0.36 | 0.26 | 0.16 | TRUE |