TWAS
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Models
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Traits
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Traits
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Blood Red Count
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chr3:69,093,598-70,708,646
Best TWAS P=1.89e-16 · Best GWAS P=1.19e-34 conditioned to 0.0992
69M
69.2M
69.4M
69.6M
69.8M
70M
70.2M
70.4M
70.6M
70.8M
0
10
20
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Spleen
MITF
0.38
0.29
lasso
3
0.27
1.2e-07
-6.8
8.2
1.9e-16
0.74
0.05
0.9
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
MITF
0.12
0.08
lasso
6
0.09
1.8e-09
-7.5
-6.6
3.6e-11
-0.34
1.00
0.0
TRUE