Best TWAS P=1.89e-16 · Best GWAS P=1.19e-34 conditioned to 0.0992
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | MITF | 0.38 | 0.29 | lasso | 3 | 0.27 | 1.2e-07 | -6.8 | 8.2 | 1.9e-16 | 0.74 | 0.05 | 0.9 | TRUE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | MITF | 0.12 | 0.08 | lasso | 6 | 0.09 | 1.8e-09 | -7.5 | -6.6 | 3.6e-11 | -0.34 | 1.00 | 0.0 | TRUE |