Best TWAS P=1.24e-09 · Best GWAS P=8.16e-09 conditioned to 0.0189
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZMAT3 | 0.02 | 0.01 | enet | 10 | 0.02 | 1e-05 | -4.9 | -6.1 | 1.2e-09 | -0.66 | 0.02 | 0.93 | TRUE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZMAT3 | 0.06 | 0.02 | lasso | 2 | 0.03 | 5e-04 | -4.9 | -5.6 | 1.9e-08 | -0.57 | 0.03 | 0.81 | FALSE |